WO1999019480A3 - Human receptor proteins; related reagents and methods - Google Patents

Human receptor proteins; related reagents and methods Download PDF

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Publication number
WO1999019480A3
WO1999019480A3 PCT/US1998/020939 US9820939W WO9919480A3 WO 1999019480 A3 WO1999019480 A3 WO 1999019480A3 US 9820939 W US9820939 W US 9820939W WO 9919480 A3 WO9919480 A3 WO 9919480A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
receptor proteins
human receptor
related reagents
reagents
Prior art date
Application number
PCT/US1998/020939
Other languages
French (fr)
Other versions
WO1999019480A2 (en
Inventor
Jacqueline C Timans
Johannes Eduard Maria A Debets
Theodore R Sana
J Fernando Bazan
Robert A Kastelein
Original Assignee
Schering Corp
Jacqueline C Timans
Johannes Eduard Maria A Debets
Theodore R Sana
J Fernando Bazan
Robert A Kastelein
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp, Jacqueline C Timans, Johannes Eduard Maria A Debets, Theodore R Sana, J Fernando Bazan, Robert A Kastelein filed Critical Schering Corp
Priority to AU97864/98A priority Critical patent/AU9786498A/en
Priority to JP2000516032A priority patent/JP2004512801A/en
Priority to CA002306455A priority patent/CA2306455A1/en
Priority to EP98952080A priority patent/EP1029043A1/en
Publication of WO1999019480A2 publication Critical patent/WO1999019480A2/en
Publication of WO1999019480A3 publication Critical patent/WO1999019480A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Abstract

Nucleic acids encoding mammalian, e.g., human receptors, purified receptor proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.
PCT/US1998/020939 1997-10-15 1998-10-14 Human receptor proteins; related reagents and methods WO1999019480A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU97864/98A AU9786498A (en) 1997-10-15 1998-10-14 Human receptor proteins; related reagents and methods
JP2000516032A JP2004512801A (en) 1997-10-15 1998-10-14 Human receptor proteins; related reagents and methods
CA002306455A CA2306455A1 (en) 1997-10-15 1998-10-14 Human receptor proteins; related reagents and methods
EP98952080A EP1029043A1 (en) 1997-10-15 1998-10-14 Human receptor proteins; related reagents and methods

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
US95182997A 1997-10-15 1997-10-15
US08/951,829 1997-10-15
US97163597A 1997-11-17 1997-11-17
US08/971,635 1997-11-17
US7800898P 1998-03-12 1998-03-12
US60/078,008 1998-03-12
US4071498A 1998-03-18 1998-03-18
US09/040,714 1998-03-18
US8188398P 1998-04-15 1998-04-15
US60/081,883 1998-04-15
US9598798P 1998-08-10 1998-08-10
US60/095,987 1998-08-10

Publications (2)

Publication Number Publication Date
WO1999019480A2 WO1999019480A2 (en) 1999-04-22
WO1999019480A3 true WO1999019480A3 (en) 1999-06-24

Family

ID=27556387

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1998/020939 WO1999019480A2 (en) 1997-10-15 1998-10-14 Human receptor proteins; related reagents and methods

Country Status (6)

Country Link
EP (1) EP1029043A1 (en)
JP (1) JP2004512801A (en)
AR (1) AR017518A1 (en)
AU (1) AU9786498A (en)
CA (1) CA2306455A1 (en)
WO (1) WO1999019480A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL136620A0 (en) * 1997-12-23 2001-06-14 Immunex Corp Tigirr dna and polypeptides
AU750767B2 (en) * 1998-01-23 2002-07-25 Immunex Corporation ACPL DNA and polypeptides
US20020155526A1 (en) 1998-09-30 2002-10-24 Busfield Samantha J. Novel secreted immunomodulatory proteins and uses thereof
AU2019306217B2 (en) 2018-07-16 2024-01-25 Regeneron Pharmaceuticals, Inc. Anti-IL36R antibodies

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996007739A2 (en) * 1994-09-09 1996-03-14 Neurocrine Biosciences, Incorporated Interleukin-1 type 3 receptors

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996007739A2 (en) * 1994-09-09 1996-03-14 Neurocrine Biosciences, Incorporated Interleukin-1 type 3 receptors

Non-Patent Citations (10)

* Cited by examiner, † Cited by third party
Title
A.O. CHUA AND U. GUBLER: "Sequence of the cDNA for the human fibroblast type interleukin-1 receptor", NUCLEIC ACIDS RESEARCH, vol. 17, no. 23, 11 December 1989 (1989-12-11), IRL PRESS LIMITED,OXFORD,ENGLAND, pages 10114, XP002091875 *
C.J. MCMAHAN ET AL.: "A novel Il-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types", EMBO J., vol. 10, no. 10, October 1991 (1991-10-01), OXFORD UNIVERSITY PRESS,GB;, pages 2821 - 2832, XP002091855 *
D. BUCK: "Human DNA sequence from cosmid cU72E5, between markers DXS366 and DS87", EMBL SEQUENCE DATABASE, 24 December 1995 (1995-12-24), Heidelberg, FRG, XP002099439 *
D. MUZNY ET AL.: "Xp22-164-166; HTG phase 1, 73 unordered pieces", EMBL SEQUENCE DATABASE, 5 October 1998 (1998-10-05), Heidelberg, FRG, XP002099440 *
J.E. SIMS ET AL.: "cDNA expression cloning of the IL-1 receptor, a member of the immunglobulin superfamily", SCIENCE, vol. 241, 29 July 1988 (1988-07-29), AAAS,WASHINGTON,DC,US, pages 585 - 589, XP002091876 *
P. PARNET ET AL.: "IL-1Rrp is similar to the type I interleukin-1 reecptor and its homologues T1/ST2 and IL-1R AcP", J. BIOL. CHEM., vol. 271, no. 8, 23 February 1996 (1996-02-23), AM. SOC. BIOCHEM. MOL.BIOL.,INC.,BALTIMORE,US, pages 3967 - 3970, XP002091852 *
S. TOMINAGA: "A putative protein of a growth-specific cDNA from BALB/c-3T3cells is highly similar to the extracellular portion of mouse interleukin I receptor", FEBS LETTERS, vol. 258, 1989, ELSEVIER, AMSTERDAM, NL, pages 301 - 304, XP002091854 *
S.A. GREENFEDER ET AL.: "Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex", J. BIOL. CHEM., vol. 270, no. 23, 9 June 1995 (1995-06-09), AM. SOC. BIOCHEM. MOL.BIOL.,INC.,BALTIMORE,US, pages 13757 - 13756, XP002091874 *
T. TETSUKA ET AL.: "Nucleotide sequence of a complementary DNA for human ST2", EMBL SEQUENCE DATABASE, 3 September 1992 (1992-09-03), Heidelberg, FRG, XP002091853 *
T.L. BORN ET AL.: "Cloning of a novel receptor subunit, AcPL, required for interleukin-18 signalling", J. BIOL. CHEM., vol. 273, no. 45, 6 November 1998 (1998-11-06), AM. SOC. BIOCHEM. MOL.BIOL.,INC.,BALTIMORE,US, pages 29445 - 29450, XP002091850 *

Also Published As

Publication number Publication date
JP2004512801A (en) 2004-04-30
AU9786498A (en) 1999-05-03
WO1999019480A2 (en) 1999-04-22
AR017518A1 (en) 2001-09-12
EP1029043A1 (en) 2000-08-23
CA2306455A1 (en) 1999-04-22

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