WO2001036467A3 - Mammalian receptor proteins; related reagents and methods - Google Patents

Mammalian receptor proteins; related reagents and methods Download PDF

Info

Publication number
WO2001036467A3
WO2001036467A3 PCT/US2000/031363 US0031363W WO0136467A3 WO 2001036467 A3 WO2001036467 A3 WO 2001036467A3 US 0031363 W US0031363 W US 0031363W WO 0136467 A3 WO0136467 A3 WO 0136467A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
receptor proteins
related reagents
mammalian receptor
mammalian
Prior art date
Application number
PCT/US2000/031363
Other languages
French (fr)
Other versions
WO2001036467A2 (en
Inventor
Daniel M Gorman
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Priority to EP00982122A priority Critical patent/EP1230368A2/en
Priority to JP2001538956A priority patent/JP2003523179A/en
Priority to AU19192/01A priority patent/AU1919201A/en
Priority to MXPA02005058A priority patent/MXPA02005058A/en
Priority to CA002392109A priority patent/CA2392109A1/en
Publication of WO2001036467A2 publication Critical patent/WO2001036467A2/en
Publication of WO2001036467A3 publication Critical patent/WO2001036467A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

Nucleic acids encoding mammalian, e.g., primate, receptors, purified receptor proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are described.
PCT/US2000/031363 1999-11-18 2000-11-16 Mammalian receptor proteins; related reagents and methods WO2001036467A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
EP00982122A EP1230368A2 (en) 1999-11-18 2000-11-16 Mammalian receptor proteins; related reagents and methods
JP2001538956A JP2003523179A (en) 1999-11-18 2000-11-16 Mammalian receptor proteins; related reagents and methods
AU19192/01A AU1919201A (en) 1999-11-18 2000-11-16 Mammalian receptor proteins; related reagents and methods
MXPA02005058A MXPA02005058A (en) 1999-11-18 2000-11-16 Mammalian receptor proteins; related reagents and methods.
CA002392109A CA2392109A1 (en) 1999-11-18 2000-11-16 Mammalian receptor proteins; related reagents and methods

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US44306099A 1999-11-18 1999-11-18
US09/443,060 1999-11-18
US17032099P 1999-12-13 1999-12-13
US60/170,320 1999-12-13

Publications (2)

Publication Number Publication Date
WO2001036467A2 WO2001036467A2 (en) 2001-05-25
WO2001036467A3 true WO2001036467A3 (en) 2002-05-10

Family

ID=26865975

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/031363 WO2001036467A2 (en) 1999-11-18 2000-11-16 Mammalian receptor proteins; related reagents and methods

Country Status (6)

Country Link
EP (1) EP1230368A2 (en)
JP (1) JP2003523179A (en)
AU (1) AU1919201A (en)
CA (1) CA2392109A1 (en)
MX (1) MXPA02005058A (en)
WO (1) WO2001036467A2 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6057128A (en) 1998-03-17 2000-05-02 Genetics Institute, Inc. MU-1, member of the cytokine receptor family
US7198789B2 (en) 1998-03-17 2007-04-03 Genetics Institute, Llc Methods and compositions for modulating interleukin-21 receptor activity
WO2001040467A1 (en) 1999-12-03 2001-06-07 Zymogenetics, Inc. Human cytokine receptor
US20030170823A1 (en) 1999-12-23 2003-09-11 Presnell Scott R. Novel cytokine ZCYTO18
DE60123998T2 (en) 2000-08-08 2007-09-06 Zymogenetics, Inc., Seattle SOLUBLE ZCYCTOR 11 CYTOKIN RECEPTORS
US7268223B2 (en) 2000-09-22 2007-09-11 Wyeth Isolated nucleic acid molecules which encode a soluble IL-TIF receptor or binding protein which binds to IL-TIF/IL-22, and uses thereof
US7094570B2 (en) 2003-03-11 2006-08-22 Ludwig Institute For Cancer Research Isolated nucleic acid molecules which encode a soluble IL-TIF/IL-22 receptor or binding protein which binds to IL-TIF/IL-22, and uses thereof
EP1191035A3 (en) * 2000-09-25 2002-04-17 Schering Aktiengesellschaft Three members of the cytokin-receptor class II family
WO2002066647A2 (en) * 2001-01-12 2002-08-29 Genetics Institute, Llc. Type 2 ctokine receptor and nucleic acids encoding same
CA2439636A1 (en) 2001-03-02 2002-09-12 Zymogenetics, Inc. Mouse cytokine receptor
AU2002252460A1 (en) * 2001-03-27 2002-10-08 Zymogenetics, Inc. Human cytokine receptor
IL164181A0 (en) 2002-03-22 2005-12-18 Zymogenetics Inc Anti-il-tif antibodies and methods of using in inflammation
GB0216661D0 (en) * 2002-07-17 2002-08-28 Ares Trading Sa Protein
BRPI0408315A (en) 2003-03-14 2006-03-07 Wyeth Corp isolated antibody, pharmaceutical composition, isolated nucleic acid, expression vector, host cell, methods of producing an antibody, generating an antibody or antigen binding fragment, regulating an immune response, treating or preventing a disorder associated with an immune cell in a patient to treat or prevent a hyperproliferative disorder in a patient, and diagnostic kit
DE602004028347D1 (en) 2003-03-24 2010-09-09 Zymogenetics Inc ANTI-IL-22RA ANTIBODIES AND BINDING PARTNERS AND USE METHODS OF INFLAMMATION
EP1812476B1 (en) 2004-10-22 2010-07-21 ZymoGenetics, Inc. Anti-il-22ra antibodies and binding partners and methods of using in inflammation
US7737259B2 (en) 2005-12-02 2010-06-15 Genentech, Inc. Compositions and methods for the treatment of diseases and disorders associated with cytokine signaling
WO2023187201A1 (en) * 2022-04-01 2023-10-05 Universite Catholique De Louvain Thrombopoietin receptor fragments and uses thereof

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0395853A1 (en) * 1989-03-07 1990-11-07 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Recombinant interleukin-2 receptor
WO1998037193A1 (en) * 1997-02-20 1998-08-27 Zymogenetics, Inc. Zcytor7 cytokine receptor
WO1999007848A1 (en) * 1997-08-05 1999-02-18 Zymogenetics, Inc. Mammalian cytokine receptor-11
WO1999040195A1 (en) * 1998-02-06 1999-08-12 Schering Corporation Mammalian receptor proteins; related reagents and methods
WO2000008152A1 (en) * 1998-08-04 2000-02-17 Regeneron Pharmaceuticals, Inc. Novel orphan cytokine receptors
WO2000027882A1 (en) * 1998-11-06 2000-05-18 Smithkline Beecham Corporation Hnovilr
WO2000069880A1 (en) * 1999-05-18 2000-11-23 Millennium Pharmaceuticals, Inc. Il-9/il-2 receptor-like molecules and uses thereof
WO2001040467A1 (en) * 1999-12-03 2001-06-07 Zymogenetics, Inc. Human cytokine receptor
WO2001046422A1 (en) * 1999-12-23 2001-06-28 Zymogenetics, Inc. Novel cytokine zcyto18

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0395853A1 (en) * 1989-03-07 1990-11-07 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Recombinant interleukin-2 receptor
WO1998037193A1 (en) * 1997-02-20 1998-08-27 Zymogenetics, Inc. Zcytor7 cytokine receptor
WO1999007848A1 (en) * 1997-08-05 1999-02-18 Zymogenetics, Inc. Mammalian cytokine receptor-11
WO1999040195A1 (en) * 1998-02-06 1999-08-12 Schering Corporation Mammalian receptor proteins; related reagents and methods
WO2000008152A1 (en) * 1998-08-04 2000-02-17 Regeneron Pharmaceuticals, Inc. Novel orphan cytokine receptors
WO2000027882A1 (en) * 1998-11-06 2000-05-18 Smithkline Beecham Corporation Hnovilr
WO2000069880A1 (en) * 1999-05-18 2000-11-23 Millennium Pharmaceuticals, Inc. Il-9/il-2 receptor-like molecules and uses thereof
WO2001040467A1 (en) * 1999-12-03 2001-06-07 Zymogenetics, Inc. Human cytokine receptor
WO2001046422A1 (en) * 1999-12-23 2001-06-28 Zymogenetics, Inc. Novel cytokine zcyto18

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL SEQUENCE LIBRARY 26 June 1997 (1997-06-26), ADAMS, M.D.: "Homo sapiens Chromosome 16 BAC clone CIT987-SKA-670B5 - complete genomic", XP002173708 *
DATABASE EMBL SEQUENCE LIBRARY 26 May 1999 (1999-05-26), PHILLIMORE, B.: "Human DNA sequence from clone 503F13 on chromosome 6q24.1-25.2. Contains the IFNGR1 gene for interferon gamma receptor 1 (interferon-gamma receptor alpha chain), ESTs, STSs, GSSs and a putative CpG island", XP002180424 *

Also Published As

Publication number Publication date
MXPA02005058A (en) 2002-11-07
WO2001036467A2 (en) 2001-05-25
AU1919201A (en) 2001-05-30
CA2392109A1 (en) 2001-05-25
JP2003523179A (en) 2003-08-05
EP1230368A2 (en) 2002-08-14

Similar Documents

Publication Publication Date Title
WO2001090358A3 (en) Mammalian receptor proteins; related reagents and methods
WO2001085790A3 (en) Mammalian cytokine receptor subunit proteins, related reagents and methods
WO2002020569A3 (en) Mammalian genes; related reagents and methods
ZA200604026B (en) IL-23 and its receptor ; related reagents and methods
WO2001090151A3 (en) Human receptor proteins; related reagents and methods
CY1109093T1 (en) Mammalian Receptor Proteins, Related Reagents, and Related Methods
WO2001036467A3 (en) Mammalian receptor proteins; related reagents and methods
EP2292760A3 (en) Mammalian cytokines, receptors, related reagents and methods
EP2305715A3 (en) Monoclonal antibody to osteoprotegerin binding protein
WO1999046379A3 (en) Human receptor proteins; related reagents and methods
NZ515382A (en) OX2 receptor homologs
WO2001057219A3 (en) Mammalian interleukin-1-delta and -epsilon. their use in therapeutic and diagnostic methods
WO2005065711A3 (en) Mammalian receptor proteins; related reagents and methods
WO1998032858A3 (en) Mammalian chemokines; receptors; reagents; uses
WO2001025432A3 (en) Histamine receptor
WO1999019480A3 (en) Human receptor proteins; related reagents and methods
WO1998031810A3 (en) Mammalian chemokines; receptors; reagents; uses
WO2000017363A3 (en) Interleukin-1 like molecule: interleukin-1-zeta; nucleic acids, polypeptides, antibodies, their uses
WO2001046419A3 (en) Mammalian prion proteins; related reagents and methods
CY1114280T1 (en) ANTI-COMPETITIVE ANTI-COMPETITIVE ANTI-COMPETITIVE COMPETITORS OR THEIR RELIGIONS

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CZ DE DK DM DZ EE ES FI GB GD GE HR HU ID IL IN IS JP KG KR KZ LC LK LR LT LU LV MA MD MG MK MN MX MZ NO NZ PL PT RO RU SE SG SI SK SL TJ TM TR TT TZ UA UZ VN YU ZA

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWE Wipo information: entry into national phase

Ref document number: 2392109

Country of ref document: CA

ENP Entry into the national phase

Ref document number: 2001 538956

Country of ref document: JP

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: PA/a/2002/005058

Country of ref document: MX

Ref document number: 2000982122

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2000982122

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWW Wipo information: withdrawn in national office

Ref document number: 2000982122

Country of ref document: EP