IL130921A - History of tetrahydroisoindole and xahydroisoindole - Google Patents

History of tetrahydroisoindole and xahydroisoindole

Info

Publication number
IL130921A
IL130921A IL13092195A IL13092195A IL130921A IL 130921 A IL130921 A IL 130921A IL 13092195 A IL13092195 A IL 13092195A IL 13092195 A IL13092195 A IL 13092195A IL 130921 A IL130921 A IL 130921A
Authority
IL
Israel
Prior art keywords
methyl
isoindole
halogen
ome
tetrahydro
Prior art date
Application number
IL13092195A
Other languages
English (en)
Hebrew (he)
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of IL130921A publication Critical patent/IL130921A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cosmetics (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Luminescent Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL13092195A 1994-10-04 1995-10-02 History of tetrahydroisoindole and xahydroisoindole IL130921A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4435479A DE4435479A1 (de) 1994-10-04 1994-10-04 Chinolon- und Naphthyridoncarbonsäure-Derivate
IL11549295A IL115492A (en) 1994-10-04 1995-10-02 Quinolone and naphthyridonecarboxylic acid derivatives their preparation and antibacterial compositions containing them

Publications (1)

Publication Number Publication Date
IL130921A true IL130921A (en) 2001-10-31

Family

ID=6529941

Family Applications (2)

Application Number Title Priority Date Filing Date
IL11549295A IL115492A (en) 1994-10-04 1995-10-02 Quinolone and naphthyridonecarboxylic acid derivatives their preparation and antibacterial compositions containing them
IL13092195A IL130921A (en) 1994-10-04 1995-10-02 History of tetrahydroisoindole and xahydroisoindole

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL11549295A IL115492A (en) 1994-10-04 1995-10-02 Quinolone and naphthyridonecarboxylic acid derivatives their preparation and antibacterial compositions containing them

Country Status (40)

Country Link
US (1) US5679689A (sk)
EP (1) EP0705828B1 (sk)
JP (1) JP3794737B2 (sk)
KR (1) KR100371883B1 (sk)
CN (1) CN1063747C (sk)
AT (1) ATE187171T1 (sk)
AU (1) AU697608B2 (sk)
BG (1) BG62965B1 (sk)
CA (1) CA2159547A1 (sk)
CO (1) CO4480031A1 (sk)
CU (1) CU22751A3 (sk)
CZ (1) CZ291616B6 (sk)
DE (2) DE4435479A1 (sk)
DK (1) DK0705828T3 (sk)
DZ (1) DZ1933A1 (sk)
EE (1) EE03443B1 (sk)
ES (1) ES2140599T3 (sk)
FI (1) FI954680A (sk)
GR (1) GR3032659T3 (sk)
HR (1) HRP950469B1 (sk)
HU (1) HUT73429A (sk)
IL (2) IL115492A (sk)
MA (1) MA23682A1 (sk)
MY (1) MY113196A (sk)
NO (1) NO307514B1 (sk)
NZ (1) NZ280129A (sk)
PE (1) PE29698A1 (sk)
PL (1) PL182812B1 (sk)
PT (1) PT705828E (sk)
RO (1) RO115261B1 (sk)
RU (1) RU2145604C1 (sk)
SG (1) SG38880A1 (sk)
SI (1) SI0705828T1 (sk)
SK (1) SK280877B6 (sk)
SV (1) SV1995000063A (sk)
TN (1) TNSN95099A1 (sk)
TW (1) TW364908B (sk)
UA (1) UA42797C2 (sk)
YU (1) YU63595A (sk)
ZA (1) ZA958296B (sk)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4435479A1 (de) * 1994-10-04 1996-04-11 Bayer Ag Chinolon- und Naphthyridoncarbonsäure-Derivate
DE19751948A1 (de) 1997-11-24 1999-05-27 Bayer Ag Verfahren zur Herstellung von 8-Methoxy-Chinoloncarbonsäuren
US8163769B2 (en) * 2002-03-12 2012-04-24 Abbott Laboratories Antibacterial compounds
JP2006514964A (ja) * 2003-03-12 2006-05-18 アボット・ラボラトリーズ 抗菌剤としてのナフチリジン誘導体
CA2674369C (en) 2007-01-05 2012-04-03 Daiichi Sankyo Company, Limited Fused substituted aminopyrrolidine derivative
PE20231098A1 (es) * 2019-11-28 2023-07-18 Bayer Ag Aminoquinolonas sustituidas como inhibidores de dgk alfa para la activacion inmune
KR102151969B1 (ko) * 2019-12-11 2020-09-04 주식회사 지투비 투과도 가변창의 제조방법 및 그에 의해 제조된 투과도 가변창

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0262875A (ja) * 1988-05-23 1990-03-02 Wakunaga Pharmaceut Co Ltd 新規イソインドリン誘導体
CA2030217A1 (en) * 1989-11-21 1991-05-22 Jun Imose Pyridone-carboxylic acid derivatives useful as veterinary medicines
JPH03181478A (ja) * 1989-12-08 1991-08-07 Banyu Pharmaceut Co Ltd ピリドンカルボン酸誘導体
JPH04253973A (ja) 1990-04-20 1992-09-09 Banyu Pharmaceut Co Ltd ピリドンカルボン酸誘導体
CA2076982A1 (en) * 1990-12-27 1992-06-28 Akira Okura Pyridonecarboxylic acid derivatives
DE4120646A1 (de) 1991-06-22 1992-12-24 Bayer Ag 7-isoindolinyl-chinolon- und naphthyridoncarbonsaeure-derivate
DE4121214A1 (de) * 1991-06-27 1993-01-14 Bayer Ag 7-azaisoindolinyl-chinolon- und -naphthyridoncarbonsaeure-derivate
DE4230804A1 (de) * 1992-09-15 1994-03-17 Bayer Ag 7-Isoindolinyl-chinolon- und -naphthyridon-Derivate
DE4329600A1 (de) * 1993-09-02 1995-03-09 Bayer Ag Pyrido [1,2,3-d,e] [1,3,4] benzoxadiazinderivate
DE69526595T2 (de) * 1994-02-04 2002-08-22 Dainippon Pharmaceutical Co., Ltd. Pyridoncarbonsäurederivate substituiert von bicyclischer aminogruppe, deren ester und salze, und bicyclisches amin als zwischenprodukt davon
DE4435479A1 (de) * 1994-10-04 1996-04-11 Bayer Ag Chinolon- und Naphthyridoncarbonsäure-Derivate

Also Published As

Publication number Publication date
ES2140599T3 (es) 2000-03-01
SG38880A1 (en) 1997-04-17
KR960014118A (ko) 1996-05-22
NO953931L (no) 1996-04-09
RU2145604C1 (ru) 2000-02-20
DE4435479A1 (de) 1996-04-11
HU9502888D0 (en) 1995-11-28
SK123895A3 (en) 1996-06-05
HRP950469A2 (en) 1997-08-31
YU63595A (sh) 1998-08-14
EE9500069A (et) 1996-04-15
SK280877B6 (sk) 2000-08-14
TW364908B (en) 1999-07-21
FI954680A0 (fi) 1995-10-02
CA2159547A1 (en) 1996-04-05
NO307514B1 (no) 2000-04-17
HRP950469B1 (en) 2000-12-31
ZA958296B (en) 1996-05-07
ATE187171T1 (de) 1999-12-15
CN1063747C (zh) 2001-03-28
IL115492A (en) 1999-12-22
JPH08225567A (ja) 1996-09-03
FI954680A (fi) 1996-04-05
GR3032659T3 (en) 2000-06-30
IL115492A0 (en) 1996-01-19
AU3291995A (en) 1996-04-18
DE59507324D1 (de) 2000-01-05
NO953931D0 (no) 1995-10-03
SI0705828T1 (en) 2000-02-29
CZ256895A3 (en) 1996-04-17
MY113196A (en) 2001-12-31
KR100371883B1 (ko) 2003-03-29
BG100041A (bg) 1996-05-31
NZ280129A (en) 1996-06-25
MA23682A1 (fr) 1996-07-01
PT705828E (pt) 2000-04-28
CZ291616B6 (cs) 2003-04-16
HUT73429A (en) 1996-07-29
CO4480031A1 (es) 1997-07-09
BG62965B1 (bg) 2000-12-29
RO115261B1 (ro) 1999-12-30
CN1126211A (zh) 1996-07-10
UA42797C2 (uk) 2001-11-15
CU22751A3 (es) 2002-02-28
DZ1933A1 (fr) 2002-02-17
EP0705828A1 (de) 1996-04-10
JP3794737B2 (ja) 2006-07-12
AU697608B2 (en) 1998-10-15
SV1995000063A (es) 1996-07-24
EP0705828B1 (de) 1999-12-01
PL310747A1 (en) 1996-04-15
TNSN95099A1 (fr) 1996-02-06
US5679689A (en) 1997-10-21
PE29698A1 (es) 1998-08-27
EE03443B1 (et) 2001-06-15
DK0705828T3 (da) 2000-05-15
PL182812B1 (pl) 2002-03-29

Similar Documents

Publication Publication Date Title
US8969561B2 (en) Apixaban preparation process
EP0916675B1 (en) Process for preparing sildenafil
JP6061158B2 (ja) 6−(7−((1−アミノシクロプロピル)メトキシ)−6−メトキシキノリン−4−イルオキシ)−n−メチル−1−ナフトアミド、またはそれの薬学的に許容される塩の合成中間体およびその使用
RU2138483C1 (ru) Способ получения производных 3-хинолонкарбоновой кислоты
JPH0737460B2 (ja) ピラノインドリジン誘導体及びその製造法
KR20150040340A (ko) 인테그라아제 저해제 제조를 위한 방법 및 중간체
JP2005187481A (ja) 鏡像的に純粋なシクロペンタン
IL130921A (en) History of tetrahydroisoindole and xahydroisoindole
JPH01268679A (ja) 1―シクロプロピル―キノロンカルボン酸及びその誘導体の製造方法
US20080255347A1 (en) Process for making galantamine
US5849945A (en) Aminotetralone derivatives and preparation process thereof
EP0273321B1 (en) 7-bromo-beta-carboline compound and method for producing same
JPH0524158B2 (sk)
EP3911660B1 (en) Process for preparation of 2-amino-5-hydroxy propiophenone
KR20000064811A (ko) 테트라히드로인돌리진 유도체의 제조법
JP2979358B2 (ja) フェノチアジン誘導体
CN1033583C (zh) 制备福司可林的6-(取代氨基丙酰基)衍生物的方法
EP0008610B1 (en) Furonaphthyridine compounds, process for their preparation and pharmaceutical compositions containing them
JPH07121931B2 (ja) ベンゾ〔b〕フラン誘導体
EP0216696A2 (en) Process for preparing cotarnine
JP2000007606A (ja) 7−(2−フルオロフェニル)−1−ベンゾスベロンの製造法
WO2019168025A1 (ja) モルヒナン誘導体の製造方法
Hagishita et al. Chiroptical properties of 10, 11-dihydro-5, 10-methano-5H-dibenzo (a, d) cycloheptene derivatives.
JPH05163279A (ja) オキサゾピロロキノリンエステルの製造法
JPH0539241A (ja) α,β−不飽和ケトエステル誘導体