IL117349A - תולדות n (-3בנזופוראניל) אוריאה, הכנתן ותכשירי רוקחות המכילים אותן - Google Patents
תולדות n (-3בנזופוראניל) אוריאה, הכנתן ותכשירי רוקחות המכילים אותןInfo
- Publication number
- IL117349A IL117349A IL11734996A IL11734996A IL117349A IL 117349 A IL117349 A IL 117349A IL 11734996 A IL11734996 A IL 11734996A IL 11734996 A IL11734996 A IL 11734996A IL 117349 A IL117349 A IL 117349A
- Authority
- IL
- Israel
- Prior art keywords
- carbon atoms
- chain
- straight
- branched alkyl
- denotes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/86—Benzo [b] furans; Hydrogenated benzo [b] furans with an oxygen atom directly attached in position 7
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Furan Compounds (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9504460.8A GB9504460D0 (en) | 1995-03-06 | 1995-03-06 | N-(3-Benzofuranyl)urea-derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL117349A0 IL117349A0 (en) | 1996-07-23 |
| IL117349A true IL117349A (he) | 2002-09-12 |
Family
ID=10770709
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL11734996A IL117349A (he) | 1995-03-06 | 1996-03-04 | תולדות n (-3בנזופוראניל) אוריאה, הכנתן ותכשירי רוקחות המכילים אותן |
Country Status (42)
| Country | Link |
|---|---|
| US (2) | US6399657B1 (he) |
| EP (1) | EP0731099B1 (he) |
| JP (1) | JP3204901B2 (he) |
| KR (2) | KR100405579B1 (he) |
| CN (2) | CN1176651C (he) |
| AR (1) | AR002710A1 (he) |
| AT (1) | ATE193704T1 (he) |
| BG (2) | BG62732B1 (he) |
| BR (1) | BR9600930A (he) |
| CA (1) | CA2170824A1 (he) |
| CO (1) | CO4370145A1 (he) |
| CZ (1) | CZ66796A3 (he) |
| DE (1) | DE69608721T2 (he) |
| DK (1) | DK0731099T3 (he) |
| DZ (1) | DZ1998A1 (he) |
| EE (1) | EE03921B1 (he) |
| ES (1) | ES2147320T3 (he) |
| FI (1) | FI960998A (he) |
| GB (1) | GB9504460D0 (he) |
| GR (1) | GR3034240T3 (he) |
| HK (1) | HK1013285A1 (he) |
| HR (1) | HRP960071B1 (he) |
| HU (1) | HU222282B1 (he) |
| IL (1) | IL117349A (he) |
| MA (1) | MA23815A1 (he) |
| MY (1) | MY117526A (he) |
| NO (1) | NO313672B1 (he) |
| NZ (1) | NZ286107A (he) |
| PE (1) | PE43597A1 (he) |
| PL (1) | PL189206B1 (he) |
| PT (1) | PT731099E (he) |
| RO (1) | RO116622B1 (he) |
| RU (1) | RU2162845C2 (he) |
| SI (1) | SI0731099T1 (he) |
| SK (1) | SK281817B6 (he) |
| SV (1) | SV1996000015A (he) |
| TN (1) | TNSN96035A1 (he) |
| TR (1) | TR199600177A2 (he) |
| TW (1) | TW336934B (he) |
| UA (1) | UA46714C2 (he) |
| YU (1) | YU49359B (he) |
| ZA (1) | ZA961774B (he) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9312853D0 (en) | 1993-06-22 | 1993-08-04 | Euro Celtique Sa | Chemical compounds |
| US5922751A (en) | 1994-06-24 | 1999-07-13 | Euro-Celtique, S.A. | Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same |
| US5591776A (en) | 1994-06-24 | 1997-01-07 | Euro-Celtique, S.A. | Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV |
| GB9504460D0 (en) * | 1995-03-06 | 1995-04-26 | Bayer Ag | N-(3-Benzofuranyl)urea-derivatives |
| US6166041A (en) | 1995-10-11 | 2000-12-26 | Euro-Celtique, S.A. | 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma |
| GB9525262D0 (en) * | 1995-12-11 | 1996-02-07 | Bayer Ag | Heterocyclylcarbonyl substituted benzofuranyl-ureas |
| US6075016A (en) | 1996-04-10 | 2000-06-13 | Euro-Celtique S.A. | 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity |
| GB9614718D0 (en) * | 1996-07-12 | 1996-09-04 | Bayer Ag | 3-ureido-pyridofurans and -pyridothiophenes |
| JPH10168095A (ja) * | 1996-12-10 | 1998-06-23 | Cci Corp | 炎症性腸疾患予防および治療剤 |
| JP2002529444A (ja) * | 1998-11-12 | 2002-09-10 | アリアド・ファーマシューティカルズ・インコーポレイテッド | 二環式シグナル伝達阻害剤、それを含む組成物とその用途 |
| GB2350111A (en) * | 1999-05-17 | 2000-11-22 | Bayer Ag | Oligohydroxyl substituted 3-urea-benzofuran and pyridofuran derivatives |
| GB2350112A (en) * | 1999-05-17 | 2000-11-22 | Bayer Ag | Pharmaceutically active cycloalkyl ketones |
| GB2350110A (en) * | 1999-05-17 | 2000-11-22 | Bayer Ag | Pharmaceutically active benzofurans |
| GB2350109A (en) * | 1999-05-17 | 2000-11-22 | Bayer Ag | Pharmaceutically active benzofuranyl sulfonates |
| BR0307905A (pt) * | 2002-02-22 | 2006-04-04 | Bayer Pharmaceuticals Corp | derivados de benzotiofeno e benzofurano úteis no tratamento de distúrbios hiperproliferativos |
| US7144885B2 (en) | 2002-02-22 | 2006-12-05 | Bayer Pharmaceuticals Corporation | Fused tricyclic heterocycles useful for treating hyper-proliferative disorders |
| CA2506415A1 (en) | 2002-11-19 | 2004-06-03 | Achillion Pharmaceuticals, Inc. | Substituted aryl thioureas and releated compounds; inhibitors of viral replication |
| WO2004063181A1 (en) * | 2003-01-03 | 2004-07-29 | Genzyme Corporation | Urea derivatives and their use as anti-inflammatory agents |
| TW200528459A (en) * | 2004-01-06 | 2005-09-01 | Achillion Pharmaceuticals Inc | Azabenzofuran substituted thioureas; inhibitors of viral replication |
| TW200600492A (en) * | 2004-05-18 | 2006-01-01 | Achillion Pharmaceuticals Inc | Substituted aryl acylthioureas and related compounds; inhibitors of viral replication |
| WO2006137350A1 (ja) * | 2005-06-22 | 2006-12-28 | Kissei Pharmaceutical Co., Ltd. | 新規なフロピリジン誘導体、それを含有する医薬組成物およびそれらの用途 |
| WO2008003701A2 (en) | 2006-07-05 | 2008-01-10 | Nycomed Gmbh | Combination of hmg-coa reductase inhibitors with phosphodiesterase 4 inhibitors for the treatment of inflammatory pulmonary diseases |
| US20140057978A1 (en) | 2011-03-17 | 2014-02-27 | Algiax Pharmaceuticals Gmbh | Novel use of benzofuranylsulfonates |
| WO2013156232A1 (en) * | 2012-04-16 | 2013-10-24 | Algiax Pharmaceuticals Gmbh | Use of benzofuranylsulfonates in neuropathic pain |
| JP6488000B2 (ja) | 2014-03-18 | 2019-03-20 | アルジアックス ファーマシューティカルズ ゲーエムベーハー | ２−シアノ−３−シクロプロピル−３−ヒドロキシ−ｎ−アリール−チオアクリルアミド誘導体 |
| EP3165224A1 (en) | 2015-11-09 | 2017-05-10 | Albert-Ludwigs-Universität Freiburg | Use of pde4 inhibitors for the prophylaxis and/or therapy of dyslipoproteinaemia and related disorders |
| WO2017089347A1 (en) | 2015-11-25 | 2017-06-01 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Methods and pharmaceutical compositions for the treatment of braf inhibitor resistant melanomas |
| JP6788966B2 (ja) * | 2015-12-24 | 2020-11-25 | 丸善製薬株式会社 | 化粧料 |
| EP4020024A1 (en) | 2020-12-22 | 2022-06-29 | Paul Scherrer Institut | Method for producing high aspect ratio fan-shaped optics |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA824343B (en) * | 1981-07-01 | 1983-04-27 | Upjohn Co | Pyridinyl- and imidazolyl-benzofurane and benzothiophenes |
| US4822803A (en) * | 1983-10-31 | 1989-04-18 | Merck Frosst Canada, Inc. | Benzofuran 2-carboxylic acid hydrazides useful as inhibitors of leukotriene biosynthesis |
| US4933351A (en) * | 1983-10-31 | 1990-06-12 | Merck Frosst Canada, Inc. | Benzofuran 2-carbox amides useful as inhibitors of leukoriene biosynthesis |
| US4663347A (en) | 1983-10-31 | 1987-05-05 | Merck Frosst Canada, Inc. | Benzofuran 2-carboxylic acid esters useful as inhibitors of leukotriene biosynthesis |
| EP0146243A1 (en) * | 1983-10-31 | 1985-06-26 | Merck Frosst Canada Inc. | Lipoxygenase inhibitors |
| US5087638A (en) * | 1984-06-20 | 1992-02-11 | Merck Frosst Canada, Inc. | Benzofuran derivatives |
| GB9200623D0 (en) * | 1992-01-13 | 1992-03-11 | Bayer Ag | Benzofuranyl and thiophenyl-methylthio-alkanecarboxylic acid derivatives |
| GB9309324D0 (en) * | 1993-05-06 | 1993-06-16 | Bayer Ag | Venzofuranyl-and-thiophenyl-alkanecarboxyclic acids derivatives |
| GB9504460D0 (en) * | 1995-03-06 | 1995-04-26 | Bayer Ag | N-(3-Benzofuranyl)urea-derivatives |
-
1995
- 1995-03-06 GB GBGB9504460.8A patent/GB9504460D0/en active Pending
-
1996
- 1996-02-13 HR HR960071A patent/HRP960071B1/xx not_active IP Right Cessation
- 1996-02-22 PT PT96102650T patent/PT731099E/pt unknown
- 1996-02-22 EP EP96102650A patent/EP0731099B1/en not_active Expired - Lifetime
- 1996-02-22 DK DK96102650T patent/DK0731099T3/da active
- 1996-02-22 AT AT96102650T patent/ATE193704T1/de not_active IP Right Cessation
- 1996-02-22 ES ES96102650T patent/ES2147320T3/es not_active Expired - Lifetime
- 1996-02-22 DE DE69608721T patent/DE69608721T2/de not_active Expired - Fee Related
- 1996-02-22 SI SI9630186T patent/SI0731099T1/xx unknown
- 1996-02-28 AR ARP960101567A patent/AR002710A1/es unknown
- 1996-02-29 RO RO96-00425A patent/RO116622B1/ro unknown
- 1996-03-01 MA MA24172A patent/MA23815A1/fr unknown
- 1996-03-01 CA CA002170824A patent/CA2170824A1/en not_active Abandoned
- 1996-03-01 NZ NZ286107A patent/NZ286107A/en unknown
- 1996-03-04 PL PL96313070A patent/PL189206B1/pl not_active IP Right Cessation
- 1996-03-04 BG BG100396A patent/BG62732B1/bg unknown
- 1996-03-04 FI FI960998A patent/FI960998A/fi not_active IP Right Cessation
- 1996-03-04 IL IL11734996A patent/IL117349A/he not_active IP Right Cessation
- 1996-03-04 BG BG100396A patent/BG100396A/bg unknown
- 1996-03-04 TN TNTNSN96035A patent/TNSN96035A1/fr unknown
- 1996-03-05 KR KR1019960005676A patent/KR100405579B1/ko not_active IP Right Cessation
- 1996-03-05 TR TR96/00177A patent/TR199600177A2/xx unknown
- 1996-03-05 JP JP07308496A patent/JP3204901B2/ja not_active Expired - Fee Related
- 1996-03-05 UA UA96030864A patent/UA46714C2/uk unknown
- 1996-03-05 RU RU96104360/04A patent/RU2162845C2/ru not_active IP Right Cessation
- 1996-03-05 NO NO19960884A patent/NO313672B1/no unknown
- 1996-03-05 DZ DZ960039A patent/DZ1998A1/fr active
- 1996-03-05 YU YU13396A patent/YU49359B/sh unknown
- 1996-03-05 MY MYPI96000815A patent/MY117526A/en unknown
- 1996-03-05 EE EE9600030A patent/EE03921B1/xx not_active IP Right Cessation
- 1996-03-05 CZ CZ96667A patent/CZ66796A3/cs unknown
- 1996-03-05 ZA ZA961774A patent/ZA961774B/xx unknown
- 1996-03-05 TW TW085102648A patent/TW336934B/zh active
- 1996-03-05 HU HU9600549A patent/HU222282B1/hu not_active IP Right Cessation
- 1996-03-05 SK SK297-96A patent/SK281817B6/sk unknown
- 1996-03-06 CN CNB011033924A patent/CN1176651C/zh not_active Expired - Fee Related
- 1996-03-06 CN CN96103073A patent/CN1134419A/zh active Pending
- 1996-03-06 BR BR9600930A patent/BR9600930A/pt not_active Application Discontinuation
- 1996-03-06 SV SV1996000015A patent/SV1996000015A/es unknown
- 1996-03-06 CO CO96010870A patent/CO4370145A1/es unknown
- 1996-03-06 PE PE1996000153A patent/PE43597A1/es not_active Application Discontinuation
-
1998
- 1998-12-22 HK HK98114554A patent/HK1013285A1/xx not_active IP Right Cessation
-
1999
- 1999-05-21 US US09/316,536 patent/US6399657B1/en not_active Expired - Fee Related
-
2000
- 2000-08-23 GR GR20000401927T patent/GR3034240T3/el not_active IP Right Cessation
-
2002
- 2002-05-24 US US10/154,743 patent/US6677372B2/en not_active Expired - Fee Related
-
2003
- 2003-06-24 KR KR1020030040949A patent/KR100438633B1/ko not_active IP Right Cessation
Also Published As
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| Publication | Publication Date | Title |
|---|---|---|
| IL117349A (he) | תולדות n (-3בנזופוראניל) אוריאה, הכנתן ותכשירי רוקחות המכילים אותן | |
| US6169092B1 (en) | 3-Ureido-pyridofurans and -pyridothiophenes for the treatment of inflammatory processes | |
| EP0779291B1 (en) | Heterocyclylcarbonyl substituted benzofuranyl-ureas | |
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| US6610687B1 (en) | Benzofuranylsulfonates | |
| JPH0673012A (ja) | ４−イミノキノリン、その製法およびその使用 | |
| WO2000069841A2 (en) | Benzofuranylaminoalcohols | |
| GB2350112A (en) | Pharmaceutically active cycloalkyl ketones | |
| WO2000069844A1 (en) | Oligohydroxyl substituted benzofuran-3-yl and pyridofuranylurea derivatives as phosphodiesterase iv inhibitors |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |