IE66042B1 - Fused ring analogs of nitrogen containing nonaromatic heterocycles - Google Patents

Fused ring analogs of nitrogen containing nonaromatic heterocycles

Info

Publication number
IE66042B1
IE66042B1 IE339691A IE339691A IE66042B1 IE 66042 B1 IE66042 B1 IE 66042B1 IE 339691 A IE339691 A IE 339691A IE 339691 A IE339691 A IE 339691A IE 66042 B1 IE66042 B1 IE 66042B1
Authority
IE
Ireland
Prior art keywords
alkyl
compound
amino
phenyl
formula
Prior art date
Application number
IE339691A
Other languages
English (en)
Other versions
IE913396A1 (en
Inventor
Manoj C Desai
Harry R Howard
Terry J Rosen
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IE913396A1 publication Critical patent/IE913396A1/en
Publication of IE66042B1 publication Critical patent/IE66042B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
  • Electroluminescent Light Sources (AREA)
  • Eye Examination Apparatus (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
IE339691A 1990-09-28 1991-09-27 Fused ring analogs of nitrogen containing nonaromatic heterocycles IE66042B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59042390A 1990-09-28 1990-09-28

Publications (2)

Publication Number Publication Date
IE913396A1 IE913396A1 (en) 1992-04-08
IE66042B1 true IE66042B1 (en) 1995-12-13

Family

ID=24362216

Family Applications (1)

Application Number Title Priority Date Filing Date
IE339691A IE66042B1 (en) 1990-09-28 1991-09-27 Fused ring analogs of nitrogen containing nonaromatic heterocycles

Country Status (22)

Country Link
EP (1) EP0550635B1 (OSRAM)
JP (1) JPH0772175B2 (OSRAM)
CN (1) CN1060285A (OSRAM)
AT (1) ATE121389T1 (OSRAM)
AU (1) AU651145B2 (OSRAM)
BR (1) BR9106905A (OSRAM)
CA (1) CA2089736A1 (OSRAM)
CZ (1) CZ387492A3 (OSRAM)
DE (1) DE69109125T2 (OSRAM)
DK (1) DK0550635T3 (OSRAM)
ES (1) ES2071334T3 (OSRAM)
FI (1) FI931370L (OSRAM)
HU (1) HUT68667A (OSRAM)
IE (1) IE66042B1 (OSRAM)
IL (1) IL99525A0 (OSRAM)
MX (1) MX9101274A (OSRAM)
NO (1) NO931151L (OSRAM)
PT (1) PT99064A (OSRAM)
TW (1) TW199144B (OSRAM)
WO (1) WO1992006079A1 (OSRAM)
YU (1) YU159291A (OSRAM)
ZA (1) ZA917744B (OSRAM)

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US6048859A (en) * 1992-06-29 2000-04-11 Merck & Co., Inc. Morpholine and thiomorpholine tachykinin receptor antagonists
US5637699A (en) * 1992-06-29 1997-06-10 Merck & Co., Inc. Process for preparing morpholine tachykinin receptor antagonists
AU4396193A (en) * 1992-08-04 1994-03-03 Pfizer Inc. 3-benzylamino-2-phenyl-piperidine derivatives as substance p receptor antagonists
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US5387595A (en) * 1992-08-26 1995-02-07 Merck & Co., Inc. Alicyclic compounds as tachykinin receptor antagonists
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US5344830A (en) * 1992-12-10 1994-09-06 Merck & Co., Inc. N,N-diacylpiperazine tachykinin antagonists
US5830854A (en) * 1992-12-14 1998-11-03 Merck Sharp & Dohme, Limited Method of treating cystic fibrosis using a tachykinin receptor antagonist
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US5393762A (en) * 1993-06-04 1995-02-28 Pfizer Inc. Pharmaceutical agents for treatment of emesis
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Also Published As

Publication number Publication date
WO1992006079A1 (en) 1992-04-16
HUT68667A (en) 1995-07-28
ATE121389T1 (de) 1995-05-15
IE913396A1 (en) 1992-04-08
MX9101274A (es) 1992-05-04
PT99064A (pt) 1992-08-31
ZA917744B (en) 1993-03-29
DK0550635T3 (da) 1995-09-04
HU9300898D0 (en) 1993-06-28
FI931370A0 (fi) 1993-03-26
CZ387492A3 (en) 1994-02-16
JPH06501267A (ja) 1994-02-10
DE69109125T2 (de) 1995-09-28
NO931151D0 (no) 1993-03-26
AU651145B2 (en) 1994-07-14
FI931370A7 (fi) 1993-03-26
NO931151L (no) 1993-03-26
IL99525A0 (en) 1992-08-18
FI931370L (fi) 1993-03-26
CN1060285A (zh) 1992-04-15
BR9106905A (pt) 1993-08-17
CA2089736A1 (en) 1992-03-29
TW199144B (OSRAM) 1993-02-01
AU8746391A (en) 1992-04-28
EP0550635A1 (en) 1993-07-14
JPH0772175B2 (ja) 1995-08-02
DE69109125D1 (de) 1995-05-24
YU159291A (sh) 1994-01-20
ES2071334T3 (es) 1995-06-16
EP0550635B1 (en) 1995-04-19

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