IE64006B1 - Antigens particulary envelope antigens of the virus of lymphadenopathies and of the acquired immune-deficiency syndrome and virus process for producing virus envelope antigens use of said antigens in the preparation of immunogenic compositions or for the diagnosis of the presence of antibodies against this virus - Google Patents
Antigens particulary envelope antigens of the virus of lymphadenopathies and of the acquired immune-deficiency syndrome and virus process for producing virus envelope antigens use of said antigens in the preparation of immunogenic compositions or for the diagnosis of the presence of antibodies against this virusInfo
- Publication number
- IE64006B1 IE64006B1 IE258785A IE258785A IE64006B1 IE 64006 B1 IE64006 B1 IE 64006B1 IE 258785 A IE258785 A IE 258785A IE 258785 A IE258785 A IE 258785A IE 64006 B1 IE64006 B1 IE 64006B1
- Authority
- IE
- Ireland
- Prior art keywords
- asn
- ser
- thr
- leu
- gly
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1036—Retroviridae, e.g. leukemia viruses
- C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
- C07K16/1054—Lentiviridae, e.g. HIV, FIV, SIV gag-pol, e.g. p17, p24
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/702—Specific hybridization probes for retroviruses
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/702—Specific hybridization probes for retroviruses
- C12Q1/703—Viruses associated with AIDS
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
- C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16311—Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
- C12N2740/16322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Oncology (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- AIDS & HIV (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Urology & Nephrology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8416013A FR2571968B1 (fr) | 1984-10-18 | 1984-10-18 | Virus purifie des lymphadenopathies et du syndrome d'immuno-depression acquise et antigenes d'enveloppe de ce virus, procede d'obtention de ce virus et de ces antigenes d'enveloppe de ce virus, applications de ce virus ou de ces antigenes a la preparation de compositions immunogenes ou pour le diagnostic des susdites affections. |
| GB848429099A GB8429099D0 (en) | 1984-11-16 | 1984-11-16 | Closed dna sequences |
| GB858501473A GB8501473D0 (en) | 1985-01-21 | 1985-01-21 | Cloned dna sequences |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE852587L IE852587L (en) | 1986-04-18 |
| IE64006B1 true IE64006B1 (en) | 1995-06-28 |
Family
ID=27251244
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE258785A IE64006B1 (en) | 1984-10-18 | 1985-10-18 | Antigens particulary envelope antigens of the virus of lymphadenopathies and of the acquired immune-deficiency syndrome and virus process for producing virus envelope antigens use of said antigens in the preparation of immunogenic compositions or for the diagnosis of the presence of antibodies against this virus |
Country Status (15)
| Country | Link |
|---|---|
| EP (5) | EP0462627B2 (cg-RX-API-DMAC7.html) |
| JP (4) | JP2752329B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR930000189B1 (cg-RX-API-DMAC7.html) |
| AT (6) | ATE86636T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU603543B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA1341620C (cg-RX-API-DMAC7.html) |
| DE (7) | DE3588248T2 (cg-RX-API-DMAC7.html) |
| DK (2) | DK174910B1 (cg-RX-API-DMAC7.html) |
| ES (3) | ES8705522A1 (cg-RX-API-DMAC7.html) |
| GR (1) | GR852522B (cg-RX-API-DMAC7.html) |
| HK (1) | HK1050215B (cg-RX-API-DMAC7.html) |
| IE (1) | IE64006B1 (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ230372A (cg-RX-API-DMAC7.html) |
| PT (1) | PT81338B (cg-RX-API-DMAC7.html) |
| WO (1) | WO1986002383A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (89)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8423659D0 (en) * | 1984-09-19 | 1984-10-24 | Pasteur Institut | Cloned dna sequences |
| US5610035A (en) * | 1983-12-05 | 1997-03-11 | Institut Pasteur Centre National De La Recherche Scientific | Methods for the preparation of hybridomas producing lymphadenopathy-associated virus (LAV) GP110-specific monoclonal antibodies and methods for the purification of GP110 employing said monoclonal antibodies |
| US9328391B1 (en) | 1984-08-22 | 2016-05-03 | The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Cloning and expression of HIV-1 DNA |
| US7285271B1 (en) | 1984-10-31 | 2007-10-23 | Novartis Vaccines And Diagnostics, Inc. | Antigenic composition comprising an HIV gag or env polypeptide |
| US7393949B1 (en) | 1987-12-24 | 2008-07-01 | Novartis Vaccines And Diagnostics, Inc. | Human immunodeficiency virus (HIV) nucleotide sequences |
| CA1341423C (en) | 1984-10-31 | 2003-03-04 | Paul A. Luciw | Recombinant proteins of viruses associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome |
| US7273695B1 (en) | 1984-10-31 | 2007-09-25 | Novartis Vaccines And Diagnostics, Inc. | HIV immunoassays using synthetic envelope polypeptides |
| US4725669A (en) * | 1984-11-09 | 1988-02-16 | President And Fellows Of Harvard College | Assay for detecting infection by human T-cell lymphotropic virus-III |
| US6534285B1 (en) | 1984-12-24 | 2003-03-18 | Genentech, Inc. | Molecularly cloned acquired immunodeficiency syndrome polypeptides and their methods of use |
| JP2869063B2 (ja) * | 1985-04-08 | 1999-03-10 | ジエネテイツク システムズ コ−ポレイシヨン | LAVに対する抗体と免疫的に反応性であるgagによりコードされたペプチドの発現及び使用 |
| US5773210A (en) * | 1985-04-19 | 1998-06-30 | The United States Of America As Represented By The Department Of Health And Human Services | Acquired immune deficiency syndrome (AIDS) viral envelope protein and method of testing for AIDS |
| DK171119B1 (da) * | 1985-04-19 | 1996-06-17 | Hoffmann La Roche | AIDS-viruskappeprotein, ekspressionsvektor bærende viruskappeproteinet, transformanter transformeret med ekspressionsvektoren, fremgangsmåde til fremstilling af viruskappeproteinet, fremgangsmåde til detektion af AIDS-antistoffer, fremgangsmåde til bestemmelse af AIDS-virus, vaccine mod AIDS, antistoffer mod viruskappeproteinet samt anvendelse af dette til fremstilling af en vaccine og til testnin |
| WO1986006414A1 (en) | 1985-04-29 | 1986-11-06 | Genetic Systems Corporation | Synthetic antigens for the detection of aids-related disease |
| GR862412B (en) * | 1985-09-25 | 1987-01-23 | Oncogen | Vaccines and immuinoassays for acquired immune deficiency syndrome |
| FR2593519B1 (fr) * | 1985-09-25 | 1994-01-07 | Oncogen | Vaccin contre le syndrome immunodeficitaire acquis et intermediaires pour la preparation de ce vaccin |
| GB8525615D0 (en) * | 1985-10-17 | 1985-11-20 | Hoffmann La Roche | Polypeptides |
| DE3689941D1 (de) * | 1985-10-24 | 1994-08-04 | Southwest Found Biomed Res | Synthetische peptide und deren verwendung zur diagnose und impfung für aids und arc. |
| US4839288A (en) * | 1986-01-22 | 1989-06-13 | Institut Pasteur | Retrovirus capable of causing AIDS, antigens obtained from this retrovirus and corresponding antibodies and their application for diagnostic purposes |
| US6514691B1 (en) | 1986-01-22 | 2003-02-04 | Institut Pasteur | Peptides of human immunodeficiency virus type 2 (HIV-2), antibodies against peptides of HIV-2, and methods and kits for detecting HIV-2 |
| ATE195148T1 (de) * | 1986-01-22 | 2000-08-15 | Pasteur Institut | Prozess zur rekombinanten herstellung von hiv-2 - proteinen sowie zellen, die hiv-2 - proteine exprimiert |
| US4734362A (en) * | 1986-02-03 | 1988-03-29 | Cambridge Bioscience Corporation | Process for purifying recombinant proteins, and products thereof |
| US4772547A (en) * | 1986-02-03 | 1988-09-20 | Hoffmann-La Roche Inc. | HTLV-III envelope peptides |
| US6130314A (en) * | 1986-03-26 | 2000-10-10 | Genetic Systems Corporation | Synthetic antigen for the detection of AIDS-related disease |
| US5075211A (en) * | 1986-03-26 | 1991-12-24 | Genetic Systems Corporation | Synthetic antigen for the detection of AIDS-related disease |
| US4879212A (en) * | 1986-04-02 | 1989-11-07 | United Biomedical Inc. | Peptide composition and method for the detection of antibodies to HTLV-III |
| US4943627A (en) * | 1986-06-12 | 1990-07-24 | Biogen, Inc. | Peptides involved in the pathogenesis of HIV infection |
| WO1987007616A1 (en) * | 1986-06-12 | 1987-12-17 | Biogen N.V. | Peptides involved in the pathogenesis of hiv infection |
| US5017688A (en) * | 1986-06-12 | 1991-05-21 | Biogen, Inc. | Peptides involved in the pathogenesis of HIV infection |
| DE3722272A1 (de) * | 1986-07-08 | 1988-01-21 | Bio Rad Laboratories | Differenzierung des krankheitszustandes bei aids-antikoerpertests |
| EP0525828A3 (en) * | 1986-08-01 | 1993-02-24 | Repligen Corporation | Recombinant polypeptides and their uses, including assay for aids virus |
| US5166050A (en) * | 1986-08-20 | 1992-11-24 | Bristol-Myers Squibb Company | Monoclonal antibodies and peptides useful in treating and diagnosing HIV infections |
| NZ221440A (en) * | 1986-08-20 | 1991-11-26 | Genetic Systems Corp | Composition containing monoclonal antibodies/peptides useful in treating and diagnosing hiv infections |
| ES2056054T3 (es) * | 1986-09-19 | 1994-10-01 | Oncogen | Uso de linfocitos t activados para preparar una composicion farmaceutica para el tratamiento del sida. |
| US5976541A (en) * | 1988-01-26 | 1999-11-02 | The United States Of America As Represented By The Department Of Health And Human Services | Potent peptide for stimulation of cytotoxic T lymphocytes specific for the HIV-1 envelope |
| AU592258B2 (en) * | 1986-12-30 | 1990-01-04 | United States of America, as represented by the Secretary, U.S. Department of Commerce, The | Synthetic peptides which induce cellular immunity to the aids virus and aids viral proteins |
| FR2614025B1 (fr) * | 1987-04-15 | 1990-05-18 | Pasteur Institut | Peptides susceptibles d'etre reconnus par des anticorps induits contre des retrovirus d'immunodeficience humaine (virus hiv) leurs applications au diagnostic des infections dues a certains de ces virus et, le cas echeant, a la vaccination contre le sida |
| ATE154808T1 (de) * | 1987-01-16 | 1997-07-15 | Pasteur Institut | Peptide mit den immunologischen eigenschaften von hiv-2 |
| FR2610632B1 (fr) * | 1987-02-11 | 1990-12-21 | Pasteur Institut | Peptides caracteristiques des retrovirus d'immunodeficience humaine (virus hiv) leurs applications au diagnostic des infections dues a certains de ces virus et, le cas echeant, a la vaccination contre le sida |
| ES2102347T3 (es) * | 1987-02-20 | 1997-08-01 | Genentech Inc | Metodos y composiciones para la utilizacion de polipeptidos env y anticuerpos anti-env de hiv. |
| NO881151L (no) * | 1987-03-27 | 1988-09-28 | Syntello Ab | Syntetisk hiv-1-antigen. |
| AU1711888A (en) * | 1987-04-24 | 1988-12-02 | Biogen, Inc. | Immunotherapeutic methods and compositions |
| US5834599A (en) * | 1987-05-29 | 1998-11-10 | Tanox Biosystems, Inc. | Immunoconjugates which neutralize HIV-1 infection |
| US5981278A (en) * | 1987-05-29 | 1999-11-09 | Tanox, Inc. | Chimeric monoclonal antibodies which neutralize HIV-1 infection and their applications in therapy and prevention for AIDS |
| WO1988009181A2 (en) * | 1987-05-29 | 1988-12-01 | Tanox Biosystems, Inc. | Monoclonal antibodies neutralizing hiv-1 |
| FI872409A0 (fi) * | 1987-05-29 | 1987-05-29 | Labsystems Oy | Foerfarande foer detektering av hiv-1 motkroppar. |
| US6657050B1 (en) | 1987-05-29 | 2003-12-02 | Tanox, Inc. | Chimeric viral-neutralizing immunoglobulins |
| GB8714802D0 (en) * | 1987-06-24 | 1987-07-29 | Proteus Biotech Ltd | Synthetic polypeptides |
| NL8702403A (nl) * | 1987-10-09 | 1989-05-01 | Stichting Centr Diergeneeskund | Oligopeptiden en gebruik daarvan voor diagnostische en vaccinatiedoeleinden voor aids en arc. |
| EP0317804B1 (en) * | 1987-11-24 | 1995-10-04 | Abbott Laboratories | HIV peptides and methods for detection of HIV |
| SE8705197D0 (sv) * | 1987-12-30 | 1987-12-30 | Jonas Blomberg | New peptides, two diagnostic methods using the peptides and a medicament based on the peptides |
| US5820865A (en) * | 1988-01-26 | 1998-10-13 | The United States Of America As Represented By The Department Of Health And Human Services | Method to induce cytotoxic T Lymphocytes specific for a broad array of HIV-1 isolates using hybrid synthetic peptides |
| DE68926499T2 (de) * | 1988-01-26 | 1996-12-19 | The United States Of America, Represented By The Secretary, U.S. Department Of Commerce, Springfield, Va. | Synthetisches antigen zum bewirken einer anti-hiv-reaktion |
| CA1341285C (en) * | 1988-02-12 | 2001-08-14 | Chang Yi Wang | Synthetic peptides for the detection of antibodies to hiv gp120 envelope protein for diagnosis of aids and pre-aids conditions and as vaccines |
| US5763160A (en) * | 1988-02-12 | 1998-06-09 | United Biomedical, Inc. | Synthetic peptides and process of using same for the detection of antibodies to human immunodeficiency virus (HIV) gp120 envelope protein, diagnosis of AIDS and pre-AIDS conditions and as vaccines |
| US5562905A (en) * | 1988-04-26 | 1996-10-08 | E. I. Du Pont De Nemours And Company | Human immunodeficiency virus (hiv) env-coded peptide capable of eliciting hiv-inhibiting antibodies in mammals |
| EP0339504A3 (en) * | 1988-04-26 | 1990-09-12 | The Du Pont Merck Pharmaceutical Company | Human immunodeficiency virus (hiv) env-coded peptide capable of eliciting hiv-inhibiting antibodies in mammals |
| FR2632310B1 (fr) * | 1988-06-06 | 1992-04-10 | Pasteur Institut | Peptides ayant des proprietes protectrices d'un virus pathogene du type hiv dans des cellules sensibles |
| EP0345375B1 (en) * | 1988-06-09 | 1995-03-22 | N.V. Innogenetics S.A. | HIV-3 retrovirus and its use |
| EP0346022B1 (en) * | 1988-06-10 | 1996-02-14 | United Biomedical, Inc. | Peptide fragments of HIV |
| US5185147A (en) * | 1988-08-19 | 1993-02-09 | Cellular Products, Inc. | Short polypeptide sequences useful in the production and detection of antibodies against human immunodeficiency virus |
| WO1990009805A1 (en) * | 1989-02-28 | 1990-09-07 | New York University | Human monoclonal antibodies to human immunodeficiency virus |
| US5731189A (en) * | 1989-02-28 | 1998-03-24 | New York University | Human monoclonal antibodies to human immunodeficiency virus |
| GB8910145D0 (en) * | 1989-05-03 | 1989-06-21 | Connaught Lab | Synthetic peptides for an hiv-1 vaccine |
| FR2647810B1 (fr) * | 1989-06-02 | 1994-07-22 | Pasteur Institut | Amorces oligonucleotidiques pour l'amplification du genome des retrovirus du type hiv-2 et siv, et leurs applications au diagnostic in vitro des infections dues a ces virus |
| WO1990015066A2 (fr) * | 1989-06-02 | 1990-12-13 | Institut Pasteur | Sequences nucleotidiques issues du genome des retrovirus du type hiv-1, hiv-2 et siv, et leurs applications notamment pour l'amplification des genomes de ces retrovirus et pour le diagnostic in vitro des infections dues a ces virus |
| US7022814B1 (en) | 1992-01-21 | 2006-04-04 | Institut Pasteur And Institut National De La Sante Et De La Recherche Medicale | Nucleotide sequences derived from the genome of retroviruses of the HIV-1, HIV-2 and SIV type, and their uses in particular for the amplification of the genomes of these retroviruses and for the in vitro diagnosis of the diseases due to these viruses |
| US6165710A (en) * | 1989-10-23 | 2000-12-26 | Robinson; James E. | Method for immobilizing viral glycoproteins for use in solid-phase immunoassays |
| US6248574B1 (en) | 1989-12-13 | 2001-06-19 | Avigdor Shaffermann | Polypeptides selectively reactive with antibodies against human immunodeficiency virus and vaccines comprising the polypeptides |
| WO1991009869A1 (en) * | 1990-01-05 | 1991-07-11 | Medical Research Council | Hiv-1 core protein fragments |
| SE468168B (sv) * | 1990-02-20 | 1992-11-16 | Replico Medical Ab | Hiv-1, p24 peptider, diagnostiska antigener och foerfarande foer saerskiljande diagnostik av preliminaert hiv-1 positiva serumprov |
| DE69009066T3 (de) | 1990-06-15 | 2001-07-19 | Innogenetics N.V., Gent | SIV cpz-ant Retrovirus und seine Anwendungen. |
| US5346989A (en) * | 1990-08-22 | 1994-09-13 | Syntello Vaccine Development Kb | Peptides for use in induction of T cell activation against HIV-1 |
| DE69117965T2 (de) * | 1990-09-27 | 1996-11-14 | Pasteur Institut | Peptide, welche hiv-retroviren-hemmende antikörper induzieren, sowie gegen diese peptide gerichtete antikörper |
| WO1992005800A1 (en) * | 1990-09-27 | 1992-04-16 | Syntello Vaccin Development Kb | Peptides for use in vaccination and induction of neutralizing antibodies against human immunodeficiency virus |
| US5840313A (en) * | 1990-09-27 | 1998-11-24 | Syntello Vaccine Development Kb | Peptides for use in vaccination and induction of neutralizing antibodies against human immunodeficiency virus |
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| JPS59104325A (ja) * | 1982-12-07 | 1984-06-16 | Japan Found Cancer | ヒト白血病ウイルスの遺伝子rnaに相補性を示すdna |
| EP0115459A3 (en) * | 1983-01-26 | 1986-11-20 | University Of Medicine And Dentistry Of New Jersey | Hematological prediction of sepsis and other disease states |
| JP2780020B2 (ja) * | 1983-04-27 | 1998-07-23 | プレジデント アンド フェロウズ オブ ハーバード カレッジ | ヒトt細胞白血病ウイルス抗原及び該抗原を用いる検出方法 |
| GB8423659D0 (en) * | 1984-09-19 | 1984-10-24 | Pasteur Institut | Cloned dna sequences |
| US4520113A (en) * | 1984-04-23 | 1985-05-28 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Serological detection of antibodies to HTLV-III in sera of patients with AIDS and pre-AIDS conditions |
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| JPS60246102A (ja) * | 1984-05-21 | 1985-12-05 | Matsushita Electric Ind Co Ltd | 分布結合回路 |
| US9328391B1 (en) | 1984-08-22 | 2016-05-03 | The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Cloning and expression of HIV-1 DNA |
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| CA1341423C (en) * | 1984-10-31 | 2003-03-04 | Paul A. Luciw | Recombinant proteins of viruses associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome |
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