ATE195148T1 - Prozess zur rekombinanten herstellung von hiv-2 - proteinen sowie zellen, die hiv-2 - proteine exprimiert - Google Patents

Prozess zur rekombinanten herstellung von hiv-2 - proteinen sowie zellen, die hiv-2 - proteine exprimiert

Info

Publication number
ATE195148T1
ATE195148T1 AT89101328T AT89101328T ATE195148T1 AT E195148 T1 ATE195148 T1 AT E195148T1 AT 89101328 T AT89101328 T AT 89101328T AT 89101328 T AT89101328 T AT 89101328T AT E195148 T1 ATE195148 T1 AT E195148T1
Authority
AT
Austria
Prior art keywords
proteins
hiv
cells
recombinant production
express
Prior art date
Application number
AT89101328T
Other languages
English (en)
Inventor
Luc Montagnier
Solange Chamaret
Denise Guetard
Marc Alizon
Francois Clavel
Mireille Guyader
Pierre Sonigo
Francoise Brun-Vezinet
Marianne Rey
Christine Rouzioux
Christine Katlama
Original Assignee
Pasteur Institut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27576220&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE195148(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from FR8600910A external-priority patent/FR2593189B1/fr
Priority claimed from FR8600911A external-priority patent/FR2593190B1/fr
Priority claimed from FR8601635A external-priority patent/FR2593922B1/fr
Priority claimed from FR8601985A external-priority patent/FR2594229B1/fr
Priority claimed from US06/835,228 external-priority patent/US4839288A/en
Priority claimed from FR8603881A external-priority patent/FR2596063B1/fr
Priority claimed from FR8604215A external-priority patent/FR2597500B1/fr
Application filed by Pasteur Institut filed Critical Pasteur Institut
Application granted granted Critical
Publication of ATE195148T1 publication Critical patent/ATE195148T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G01N33/56988—HIV or HTLV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/15—Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus, feline leukaemia virus, human T-cell leukaemia-lymphoma virus
    • G01N2333/155—Lentiviridae, e.g. visna-maedi virus, equine infectious virus, FIV, SIV
    • G01N2333/16—HIV-1, HIV-2
    • G01N2333/162—HIV-1, HIV-2 env, e.g. gp160, gp110/120, gp41, V3, peptid T, DC4-Binding site
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Communicable Diseases (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Wood Science & Technology (AREA)
  • AIDS & HIV (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
AT89101328T 1986-01-22 1987-01-22 Prozess zur rekombinanten herstellung von hiv-2 - proteinen sowie zellen, die hiv-2 - proteine exprimiert ATE195148T1 (de)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
FR8600910A FR2593189B1 (fr) 1986-01-22 1986-01-22 Nouveau retrovirus susceptible de provoquer le sida, antigenes obtenus a partir de ce retrovirus et anticorps correspondants et leurs applications au diagnostic du sida
FR8600911A FR2593190B1 (fr) 1986-01-22 1986-01-22 Nouveau retrovirus susceptible de provoquer le sida, antigenes obtenus a partir de ce retrovirus et anticorps correspondants et leurs applications au diagnostic du sida
FR8601635A FR2593922B1 (fr) 1986-02-06 1986-02-06 Nouveau retrovirus susceptible de provoquer le sida, antigenes obtenus a partir de ce retrovirus et anticorps correspondants et leurs applications au diagnostic du sida
FR8601985A FR2594229B1 (fr) 1986-02-13 1986-02-13 Nouveau retrovirus du type lav-ii susceptible de provoquer le sida, antigenes obtenus a partir de ce retrovirus et anticorps correspondants et leurs applications au diagnostic du sida
US06/835,228 US4839288A (en) 1986-01-22 1986-03-03 Retrovirus capable of causing AIDS, antigens obtained from this retrovirus and corresponding antibodies and their application for diagnostic purposes
FR8603881A FR2596063B1 (fr) 1986-03-18 1986-03-18 Nouveau retrovirus susceptible de provoquer le sida, antigenes obtenus a partir de ce retrovirus et anticorps correspondants et leurs applications au diagnostic du sida
FR8604215A FR2597500B1 (fr) 1986-03-24 1986-03-24 Nouveau retrovirus susceptible de provoquer le sida, antigenes obtenus a partir de ce retrovirus et anticorps correspondants et leurs applications au diagnostic du sida
US91608086A 1986-10-06 1986-10-06
US93318486A 1986-11-21 1986-11-21

Publications (1)

Publication Number Publication Date
ATE195148T1 true ATE195148T1 (de) 2000-08-15

Family

ID=27576220

Family Applications (2)

Application Number Title Priority Date Filing Date
AT87400151T ATE47725T1 (de) 1986-01-22 1987-01-22 Zum hervorrufen von aids geeigneter retrovirus vom typ hiv-2, sowie seine antigen- und nukleinsaeure-bestandteile.
AT89101328T ATE195148T1 (de) 1986-01-22 1987-01-22 Prozess zur rekombinanten herstellung von hiv-2 - proteinen sowie zellen, die hiv-2 - proteine exprimiert

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT87400151T ATE47725T1 (de) 1986-01-22 1987-01-22 Zum hervorrufen von aids geeigneter retrovirus vom typ hiv-2, sowie seine antigen- und nukleinsaeure-bestandteile.

Country Status (15)

Country Link
EP (2) EP0320495B1 (de)
JP (7) JP2611106B2 (de)
AR (1) AR243931A1 (de)
AT (2) ATE47725T1 (de)
AU (1) AU601397B2 (de)
DE (3) DE239425T1 (de)
DK (2) DK175959B1 (de)
ES (1) ES2150897T3 (de)
GR (3) GR880300056T1 (de)
HK (1) HK62091A (de)
NZ (1) NZ219024A (de)
OA (1) OA08468A (de)
PT (1) PT84182B (de)
SG (1) SG28591G (de)
WO (1) WO1987004459A1 (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987002892A1 (en) * 1985-11-14 1987-05-21 President And Fellows Of Harvard College T-lymphotrophic virus
AU608294B2 (en) * 1987-01-16 1991-03-28 Institut Pasteur Peptides having immunological properties 2-hiv-2
EP0750041B1 (de) * 1987-01-16 2008-12-10 Institut Pasteur HIV-2 und SIV-1 Nukleotidsequenzen
EP0287226A1 (de) * 1987-03-23 1988-10-19 Hiver Limited Impfstoff
SE8701765L (sv) * 1987-04-28 1988-10-29 Statens Bakteriologiska Lab Analysmetod och medel foer denna
US4812556A (en) * 1987-05-18 1989-03-14 Virovahl Synthetic peptide antigen for the detection of HIV-2 infection
FR2620030B1 (fr) * 1987-09-07 1990-03-23 Transgene Sa Vecteur d'expression des proteines du virus hiv-2, un agent causal du sida, culture cellulaire infectee ou transformee par ce vecteur, proteines obtenues, vaccin et anticorps obtenus
US5780038A (en) * 1987-11-16 1998-07-14 Roche Diagnostic Systems, Inc. HIV-2 envelope polypeptides
ATE87487T1 (de) * 1987-11-16 1993-04-15 Hoffmann La Roche Rekombinante hiv-2 polypeptide.
AU3063389A (en) * 1988-01-08 1989-08-01 Dpz Deutsches Primatenzentrum Gesellschaft M.B.H. Hiv-2-type retroviruses of primates, vaccines, diagnostic and pharmaceutical compositions
US6210874B1 (en) 1988-01-27 2001-04-03 Biochem Immunosystems, Inc. Synthetic peptides and mixtures thereof for detecting HIV antibodies
WO1989009815A1 (en) * 1988-04-04 1989-10-19 Research Corporation Technologies, Inc. Novel virus of the hiv-2 family and methods of detection therefor
US5208321A (en) 1988-06-09 1993-05-04 Institut Pasteur HIV-2 transmembrane glycoprotein homodimer (GP 80)
US6197496B1 (en) 1988-06-09 2001-03-06 Institut Pasteur Immunological reagents and diagnostic methods for the detection of human immunodeficiency virus type 2 utilizing multimeric forms of the envelope proteins gp300, p200, and p90/80
ATE120234T1 (de) * 1988-06-09 1995-04-15 Innogenetics Nv Hiv-3-retrovirus und seine verwendung.
EP0345559A3 (de) * 1988-06-10 1990-07-11 Abbott Laboratories HIV-2-Varianten
ATE141946T1 (de) * 1988-06-14 1996-09-15 Qiagen Gmbh Hiv-2-virusvarianten
CA2032505C (fr) * 1989-05-12 2001-07-10 Ara Hovanessian Antigenes de la glycoproteine transmembranaire d'enveloppe d'un retrovirus humain du type hiv-2 antigenes presentant avec eux une parente immunologique
FR2646854A1 (fr) * 1989-05-12 1990-11-16 Pasteur Institut Antigenes de la glycoproteine transmembranaire d'enveloppe d'un retrovirus humain du type hiv-2 antigenes presentant avec eux une parente immunologique
ATE131731T1 (de) * 1989-05-31 1996-01-15 Pasteur Institut Hiv-2-eho-retrovirus-proteine und -glycoproteine, antikörper gegen sie, verwendung für diagnostische zwecke
FR2647810B1 (fr) * 1989-06-02 1994-07-22 Pasteur Institut Amorces oligonucleotidiques pour l'amplification du genome des retrovirus du type hiv-2 et siv, et leurs applications au diagnostic in vitro des infections dues a ces virus
US7022814B1 (en) 1992-01-21 2006-04-04 Institut Pasteur And Institut National De La Sante Et De La Recherche Medicale Nucleotide sequences derived from the genome of retroviruses of the HIV-1, HIV-2 and SIV type, and their uses in particular for the amplification of the genomes of these retroviruses and for the in vitro diagnosis of the diseases due to these viruses
CA2585164C (fr) 1989-06-02 2010-02-02 Institut Pasteur Sequences nucleotidiques issues du genome des retrovirus du type hiv-1, hiv-2 et siv, et leurs applications notamment pour l'amplification des genomes de ces retrovirus et pour lediagnostic in vitro des infections dues a ces virus
FR2647809B1 (fr) * 1989-06-02 1991-09-20 Pasteur Institut Amorces oligonucleotidiques pour l'amplification du genome des retrovirus du type hiv-1, hiv-2 et siv, et leurs applications au diagnostic in vitro des infections dues a ces virus
FR2657016B1 (fr) * 1990-01-16 1995-08-25 Clonatec Sa Peptides derivant de la glycoproteine d'enveloppe du virus-hiv-2, leurs applications a la detection d'une infection due a ce virus et a la vaccination contre le sida.
EP0438332B1 (de) * 1990-01-16 1998-04-08 Orgenics Ltd. Peptide, von Virus-HIV-Hüllen-Glycoproteinen abstammend, deren Verwendung zum Nachweis einer Infektion dieser Viren und für die Impfung gegen AIDS
DE69009066T3 (de) * 1990-06-15 2001-07-19 Innogenetics N.V., Gent SIV cpz-ant Retrovirus und seine Anwendungen.
GB9108652D0 (en) * 1991-04-23 1991-06-12 Antisoma Ltd Immunoreactive compounds
DE4233646C2 (de) * 1992-10-06 2003-10-23 Dade Behring Marburg Gmbh Retrovirus aus der HIV-Gruppe und dessen Verwendung
DE59309207D1 (de) * 1992-10-06 1999-01-21 Dade Behring Marburg Gmbh Retrovirus aus der HIV-Gruppe und dessen Verwendung
DE4405810A1 (de) 1994-02-23 1995-08-24 Behringwerke Ag Von einem Retrovirus aus der HIV-Gruppe abgeleitete Peptide und deren Verwendung
US5962665A (en) 1997-06-16 1999-10-05 Abbott Laboratories Nucleic acid primers and probes for detecting HIV-1 and HIV-2
FR2767337B1 (fr) 1997-08-14 2002-07-05 Pasteur Institut Sequences nucleiques de polypeptides exportes de mycobacteri es, vecteurs les comprenant et applications au diagnostic et a la prevention de la tuberculose
AU2002230545B2 (en) 2000-10-23 2006-09-21 Gen-Probe Incorporated Compositions and methods for detecting human immunodeficiency virus 2 (HIV-2)
WO2005061738A1 (en) 2003-12-19 2005-07-07 Gen-Probe Incorporated Compositions, methods and kits for detecting the nucleic acids of hiv-1 and hiv-2
JP6721772B1 (ja) 2019-03-26 2020-07-15 斉藤　幹雄 清掃装置

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4652599A (en) * 1984-04-23 1987-03-24 The United States Of America As Represented By The Department Of Health And Human Services Method of continuous production of retroviruses (HTLV-III) from patients with AIDS and pre-AIDS using permissive cells
ES8705522A1 (es) * 1984-10-18 1987-05-01 Pasteur Institut Un procedimiento para la preparacion de derivados purificados de una glicoproteina.
US4600413A (en) * 1984-12-10 1986-07-15 Sundstrand Corporation Centrifugal deaerator and pump
JP3105581B2 (ja) * 1991-07-03 2000-11-06 内橋エステック株式会社 面状温度ヒュ−ズ

Also Published As

Publication number Publication date
JP2874846B2 (ja) 1999-03-24
JP2771519B2 (ja) 1998-07-02
WO1987004459A1 (fr) 1987-07-30
SG28591G (en) 1993-02-19
ES2150897T3 (es) 2000-12-16
GR3001096T3 (en) 1992-04-17
JPH0975092A (ja) 1997-03-25
DE3760912D1 (en) 1989-12-07
DE3752319T2 (de) 2001-03-15
GR880300056T1 (en) 1988-10-18
DK493487A (da) 1987-11-17
JP2611106B2 (ja) 1997-05-21
AU6891187A (en) 1987-08-14
JP2801162B2 (ja) 1998-09-21
JPH06113833A (ja) 1994-04-26
GR3034708T3 (en) 2001-01-31
EP0239425A1 (de) 1987-09-30
EP0320495A1 (de) 1989-06-14
DK175959B1 (da) 2005-08-29
DK493487D0 (da) 1987-09-21
JPH08113598A (ja) 1996-05-07
EP0320495B1 (de) 2000-08-02
EP0239425B1 (de) 1989-11-02
DE239425T1 (de) 1988-06-30
JPH07233196A (ja) 1995-09-05
ATE47725T1 (de) 1989-11-15
OA08468A (fr) 1988-07-29
HK62091A (en) 1991-08-16
DK200500170A (da) 2005-02-04
PT84182A (pt) 1987-02-01
DE3752319D1 (de) 2000-09-07
JP2931294B2 (ja) 1999-08-09
JPH0937778A (ja) 1997-02-10
DK176253B1 (da) 2007-04-30
JP2735521B2 (ja) 1998-04-02
JPH08275783A (ja) 1996-10-22
AR243931A1 (es) 1993-09-30
PT84182B (pt) 1989-09-14
NZ219024A (en) 1990-04-26
JPH1118768A (ja) 1999-01-26
AU601397B2 (en) 1990-09-13

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time