FR2593189B1 - Nouveau retrovirus susceptible de provoquer le sida, antigenes obtenus a partir de ce retrovirus et anticorps correspondants et leurs applications au diagnostic du sida - Google Patents

Nouveau retrovirus susceptible de provoquer le sida, antigenes obtenus a partir de ce retrovirus et anticorps correspondants et leurs applications au diagnostic du sida

Info

Publication number
FR2593189B1
FR2593189B1 FR8600910A FR8600910A FR2593189B1 FR 2593189 B1 FR2593189 B1 FR 2593189B1 FR 8600910 A FR8600910 A FR 8600910A FR 8600910 A FR8600910 A FR 8600910A FR 2593189 B1 FR2593189 B1 FR 2593189B1
Authority
FR
France
Prior art keywords
retrovirus
aids
applications
new
corresponding antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8600910A
Other languages
English (en)
Other versions
FR2593189A1 (fr
Inventor
Luc Montagnier
Solange Chamaret
Denise Guetard
Marc Alizon
Francois Clavel
Francoise Brun-Vezinet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Pasteur de Lille
Original Assignee
Institut Pasteur de Lille
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut Pasteur de Lille filed Critical Institut Pasteur de Lille
Priority to FR8600910A priority Critical patent/FR2593189B1/fr
Priority to US06/835,228 priority patent/US4839288A/en
Priority to US07/003,764 priority patent/US5051496A/en
Priority to DE198787400151T priority patent/DE239425T1/de
Priority to AU68911/87A priority patent/AU601397B2/en
Priority to DE8787400151T priority patent/DE3760912D1/de
Priority to AR87306572A priority patent/AR243931A1/es
Priority to ZA87469A priority patent/ZA87469B/xx
Priority to PT84182A priority patent/PT84182B/pt
Priority to AT89101328T priority patent/ATE195148T1/de
Priority to AT87400151T priority patent/ATE47725T1/de
Priority to ES89101328T priority patent/ES2150897T3/es
Priority to DE3752319T priority patent/DE3752319T2/de
Priority to NZ219024A priority patent/NZ219024A/en
Priority to EP87400151A priority patent/EP0239425B1/fr
Priority to KR1019870700858A priority patent/KR910002428B1/ko
Priority to EP89101328A priority patent/EP0320495B1/fr
Priority to IE870174A priority patent/IE870174L/xx
Priority to JP62500920A priority patent/JP2865203B2/ja
Priority to ES87400151T priority patent/ES2013295B3/es
Priority to PCT/FR1987/000025 priority patent/WO1987004459A1/fr
Priority to OA59050A priority patent/OA08468A/fr
Priority to US07/013,477 priority patent/US5079342A/en
Publication of FR2593189A1 publication Critical patent/FR2593189A1/fr
Priority to DK198704934A priority patent/DK175959B1/da
Priority to GR88300056T priority patent/GR880300056T1/el
Application granted granted Critical
Publication of FR2593189B1 publication Critical patent/FR2593189B1/fr
Priority to GR89400288T priority patent/GR3001096T3/el
Priority to US07/462,353 priority patent/US5055391A/en
Priority to US07/462,908 priority patent/US5066782A/en
Priority to US07/462,984 priority patent/US5030718A/en
Priority to SG285/91A priority patent/SG28591G/en
Priority to US07/703,048 priority patent/US5268265A/en
Priority to HK620/91A priority patent/HK62091A/xx
Priority to US07/754,903 priority patent/US5578715A/en
Priority to US07/756,998 priority patent/US5310651A/en
Priority to US07/810,824 priority patent/US5306614A/en
Priority to JP5012972A priority patent/JP2611106B2/ja
Priority to US08/132,919 priority patent/US5545726A/en
Priority to US08/202,260 priority patent/US5597896A/en
Priority to US08/214,299 priority patent/US5830641A/en
Priority to JP6329070A priority patent/JPH07233196A/ja
Priority to US08/392,613 priority patent/US6429306B1/en
Priority to US08/468,093 priority patent/US5866319A/en
Priority to US08/466,704 priority patent/US5889158A/en
Priority to US08/467,161 priority patent/US6316183B1/en
Priority to US08/470,489 priority patent/US7115363B1/en
Priority to US08/470,487 priority patent/US6037165A/en
Priority to US08/470,491 priority patent/US6265149B1/en
Priority to JP7257991A priority patent/JP2801162B2/ja
Priority to JP7278085A priority patent/JP2735521B2/ja
Priority to JP8033969A priority patent/JP2874846B2/ja
Priority to JP8193779A priority patent/JP2771519B2/ja
Priority to JP10119235A priority patent/JP2931294B2/ja
Priority to US09/143,095 priority patent/US6296807B1/en
Priority to US09/191,384 priority patent/US6514691B1/en
Priority to GR20000402397T priority patent/GR3034708T3/el
Priority to US09/862,511 priority patent/US6664041B2/en
Priority to US09/986,634 priority patent/US20030186219A1/en
Priority to US10/133,357 priority patent/US6979535B2/en
Priority to US10/180,460 priority patent/US7341731B2/en
Priority to DK200500170A priority patent/DK176253B1/da
Priority to DK200600325A priority patent/DK200600325A/da
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G01N33/56988—HIV or HTLV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms
FR8600910A 1986-01-22 1986-01-22 Nouveau retrovirus susceptible de provoquer le sida, antigenes obtenus a partir de ce retrovirus et anticorps correspondants et leurs applications au diagnostic du sida Expired FR2593189B1 (fr)

Priority Applications (61)

Application Number Priority Date Filing Date Title
FR8600910A FR2593189B1 (fr) 1986-01-22 1986-01-22 Nouveau retrovirus susceptible de provoquer le sida, antigenes obtenus a partir de ce retrovirus et anticorps correspondants et leurs applications au diagnostic du sida
US06/835,228 US4839288A (en) 1986-01-22 1986-03-03 Retrovirus capable of causing AIDS, antigens obtained from this retrovirus and corresponding antibodies and their application for diagnostic purposes
US07/003,764 US5051496A (en) 1986-01-22 1987-01-16 Peptides related to human immunodeficiency virus II (HIV-2)
DE198787400151T DE239425T1 (de) 1986-01-22 1987-01-22 Zum hervorrufen von aids geeigneter retrovirus vom typ hiv-2, sowie seine antigen- und nukleinsaeure-bestandteile.
AU68911/87A AU601397B2 (en) 1986-01-22 1987-01-22 Retrovirus of the hiv-2 type susceptible of inducing aids, and its antigenic and nucleic constituents
DE8787400151T DE3760912D1 (en) 1986-01-22 1987-01-22 Retrovirus of the type hiv-2 capable of inducing aids, and the antigenic and nucleic acid components thereof
AR87306572A AR243931A1 (es) 1986-01-22 1987-01-22 Antigeno purificado,conjunto de reactivos para la deteccion de anticuerpos anti-hiv-2 en un fluido biologico que comprende dichos antigenos,anticuerpos,hibridomas y procedimientos.
ZA87469A ZA87469B (en) 1986-01-22 1987-01-22 Retrovirus capable of causing aids,means and methods for detecting it in vitro
PT84182A PT84182B (pt) 1986-01-22 1987-01-22 Novo retrovirus susceptivel de provocar o sida, meios e processos para a sua deteccao "in vitro"
AT89101328T ATE195148T1 (de) 1986-01-22 1987-01-22 Prozess zur rekombinanten herstellung von hiv-2 - proteinen sowie zellen, die hiv-2 - proteine exprimiert
AT87400151T ATE47725T1 (de) 1986-01-22 1987-01-22 Zum hervorrufen von aids geeigneter retrovirus vom typ hiv-2, sowie seine antigen- und nukleinsaeure-bestandteile.
ES89101328T ES2150897T3 (es) 1986-01-22 1987-01-22 Procedimiento de fabricacion recombinante de las proteinas derivadas de hiv-2 y cultivo celular que expresa proteinas de hiv-2.
DE3752319T DE3752319T2 (de) 1986-01-22 1987-01-22 Prozess zur rekombinanten Herstellung von HIV-2 - Proteinen sowie Zellen, die HIV-2 - Proteine exprimiert
NZ219024A NZ219024A (en) 1986-01-22 1987-01-22 Hiv-2 retrovirus protein and nucleic acid sequences and detection methods
EP87400151A EP0239425B1 (fr) 1986-01-22 1987-01-22 Rétrovirus du type HIV-2 susceptible de provoquer le SIDA, et ses constituants antigéniques et nucléiques
KR1019870700858A KR910002428B1 (ko) 1986-01-22 1987-01-22 Aids를 유발시킬수 있는 신규 레트로비루스의 제조방법
EP89101328A EP0320495B1 (fr) 1986-01-22 1987-01-22 Procédé de fabrication récombinante des protéines derivées de HIV-2 et culture cellulaire exprimant des protéines de HIV-2
IE870174A IE870174L (en) 1986-01-22 1987-01-22 New retrovirus capable of causing aids, means and methods¹for detecting it in vitro
JP62500920A JP2865203B2 (ja) 1986-01-22 1987-01-22 エイズの原因となる新規なレトロウィルスの抗原の混合物
ES87400151T ES2013295B3 (es) 1986-01-22 1987-01-22 Retrovirus del tipo hiv-2 susceptible de provocar el sida, sus constituyentes antigenicos y nucleicos.
PCT/FR1987/000025 WO1987004459A1 (fr) 1986-01-22 1987-01-22 Retrovirus du type hiv-2 susceptible de provoquer le sida, et ses constituants antigeniques et nucleiques
OA59050A OA08468A (fr) 1986-01-22 1987-01-22 Retrovirus du type HIV-2 susceptible de provoquer le SIDA et ses constituants antigéniques et nucléiques.
US07/013,477 US5079342A (en) 1986-01-22 1987-02-11 Cloned DNA sequences related to the entire genomic RNA of human immunodeficiency virus II (HIV-2), polypeptides encoded by these DNA sequences and use of these DNA clones and polypeptides in diagnostic kits
DK198704934A DK175959B1 (da) 1986-01-22 1987-09-21 Human HIV-2 retrovirus, der kan fremkalde AIDS, samt fremgangsmåde og middel til påvisning af dettte retrovirus in vitro
GR88300056T GR880300056T1 (en) 1986-01-22 1988-05-20 Retrovirus of the type hiv-2 capable of inducing aids, and the antigenic and nucleic acid components thereof
GR89400288T GR3001096T3 (en) 1986-01-22 1989-12-08 Retrovirus of the type hiv-2 capable of inducing aids, and the antigenic and nucleic acid components thereof
US07/462,353 US5055391A (en) 1986-01-22 1990-01-03 Method and kit or detecting antibodies to antigens of human immunodeficiency virus type 2 (hiv-2)
US07/462,908 US5066782A (en) 1986-01-22 1990-01-10 Retrovirus capable of causing AIDS, means and method for detecting it in vitro
US07/462,984 US5030718A (en) 1986-01-22 1990-01-10 Retrovirus capable of causing AIDS, antigens obtained from this retrovirus and corresponding antibodies and their application for diagnostic purposes
SG285/91A SG28591G (en) 1986-01-22 1991-04-22 Retrovirus of the type hiv-2 capable of inducing aids,and the antigenic and nucleic acid components thereof
US07/703,048 US5268265A (en) 1986-01-22 1991-05-17 Immunological complex comprising an antigen of Simian Immunodeficiency Virus (SIV) and an antibody against human immunodeficiency virus type 2 (HIV 2), and method and kit for detecting antibodies to HIV-2 reactive with antigens of SIV
HK620/91A HK62091A (en) 1986-01-22 1991-08-08 Retrovirus of the type hiv-2 capable of inducing aids,and the antigenic and nucleic acid components thereof
US07/754,903 US5578715A (en) 1986-01-22 1991-09-04 Methods, kits, and probes for diagnosing HIV-2
US07/756,998 US5310651A (en) 1986-01-22 1991-09-09 DNA probes of human immunodeficiency virus type 2 (HIV-2), and methods employing these probes for dectecting the presence of HIV-2
US07/810,824 US5306614A (en) 1986-01-22 1991-12-20 Methods and kits for diagnosing human immunodeficiency virus type 2(HIV-2)
JP5012972A JP2611106B2 (ja) 1986-01-22 1993-01-28 エイズの原因となる新規なレトロウイルス
US08/132,919 US5545726A (en) 1986-01-22 1993-10-07 Cloned DNA sequences related to the entire genomic RNA of human immunodeficiency virus II (HIV-2), polypeptides encoded by these DNA sequences and use of these DNA clones and polypeptides in diagnostic kits
US08/202,260 US5597896A (en) 1986-01-22 1994-02-25 Retrovirus human immunodeficiency virus type 2(HIV2), capable of causing AIDS, antigens obtained from this retrovirus and corresponding antibodies and their application for diagnostic purposes
US08/214,299 US5830641A (en) 1986-01-22 1994-03-17 In vitro diagnostic assays for the detection of HIV-1 or HIV-2 employing viral-specific antigens and antibodies
JP6329070A JPH07233196A (ja) 1986-01-22 1994-12-28 エイズに対するワクチンの有効成分
US08/392,613 US6429306B1 (en) 1986-01-22 1995-02-22 Nucleic acids of a human immunodeficiency virus type 2 (HIV-2)
US08/468,093 US5866319A (en) 1986-01-22 1995-06-06 Methods, kits, and probes for diagnosing HIV-2
US08/466,704 US5889158A (en) 1986-01-22 1995-06-06 Methods and kits for the detection of human immunodeficiency virus type 2 employing HIV-2 specific antibodies and antigens
US08/467,161 US6316183B1 (en) 1986-01-22 1995-06-06 Nucleic acid-based methods for the detection of human immunodeficiency virus type 2 (HIV-2)
US08/470,489 US7115363B1 (en) 1986-01-22 1995-06-06 Retrovirus capable of causing AIDS, means and methods for detecting it in vitro
US08/470,487 US6037165A (en) 1986-01-22 1995-06-06 Methods for the preparation of human immunodeficiency virus type 2 (HIV-2) and antigens encoped thereby
US08/470,491 US6265149B1 (en) 1986-01-22 1995-06-06 In vitro diagnostic methods and kits for the detection of HIV-2-specific antibodies
JP7257991A JP2801162B2 (ja) 1986-01-22 1995-10-04 エイズの原因となるレトロウイルスに対する抗体
JP7278085A JP2735521B2 (ja) 1986-01-22 1995-10-25 エイズの原因となる新規なレトロウイルスの抗原
JP8033969A JP2874846B2 (ja) 1986-01-22 1996-02-21 エイズの原因となる新規なレトロウイルスに由来する核酸
JP8193779A JP2771519B2 (ja) 1986-01-22 1996-07-23 Ｈｉｖ−２レトロウイルスの回収及び精製方法
JP10119235A JP2931294B2 (ja) 1986-01-22 1998-04-28 エイズの原因となるレトロウイルスに対する抗体を分泌するハイブリドーマ
US09/143,095 US6296807B1 (en) 1986-01-22 1998-08-28 Kits for the detection of human immunodeficiency virus type 2 (HIV-2) antigens
US09/191,384 US6514691B1 (en) 1986-01-22 1998-11-13 Peptides of human immunodeficiency virus type 2 (HIV-2), antibodies against peptides of HIV-2, and methods and kits for detecting HIV-2
GR20000402397T GR3034708T3 (en) 1986-01-22 2000-10-30 Retrovirus of the type HIV-2 capable of inducing AIDS, and the antigenic and nucleic acid components thereof.
US09/862,511 US6664041B2 (en) 1986-01-22 2001-05-23 Method for preparing a viral extract containing HIV-II RNA
US09/986,634 US20030186219A1 (en) 1986-01-22 2001-11-09 Cloned DNA sequences related to the entire genomic RNA of human immunodeficiency virus II (HIV-2), polypeptides encoded by these DNA sequences and use of these DNA clones and polypeptides in diagnostic kits
US10/133,357 US6979535B2 (en) 1986-01-22 2002-04-29 Human immunodeficiency virus type 2 (HIV-2) env polypeptide and diagnostic assays
US10/180,460 US7341731B2 (en) 1986-01-22 2002-06-27 HIV-2 antigen compositions
DK200500170A DK176253B1 (da) 1986-01-22 2005-02-04 Præparat, fremgangsmåde og kit til påvisning af antistoffer mod et humant retrovirus in vitro
DK200600325A DK200600325A (da) 1986-01-22 2006-03-06 Fremgangsmåde til in vitro detektion af en HIV-2 retrovirus

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8600910A FR2593189B1 (fr) 1986-01-22 1986-01-22 Nouveau retrovirus susceptible de provoquer le sida, antigenes obtenus a partir de ce retrovirus et anticorps correspondants et leurs applications au diagnostic du sida

Publications (2)

Publication Number Publication Date
FR2593189A1 FR2593189A1 (fr) 1987-07-24
FR2593189B1 true FR2593189B1 (fr) 1989-10-20

Family

ID=9331401

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8600910A Expired FR2593189B1 (fr) 1986-01-22 1986-01-22 Nouveau retrovirus susceptible de provoquer le sida, antigenes obtenus a partir de ce retrovirus et anticorps correspondants et leurs applications au diagnostic du sida

Country Status (3)

Country Link
JP (1) JP2865203B2 (fr)
FR (1) FR2593189B1 (fr)
ZA (1) ZA87469B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63119428A (ja) * 1986-09-19 1988-05-24 オンコーゲン エイズの処置のための養子免疫療法の方法
FR2610632B1 (fr) * 1987-02-11 1990-12-21 Pasteur Institut Peptides caracteristiques des retrovirus d'immunodeficience humaine (virus hiv) leurs applications au diagnostic des infections dues a certains de ces virus et, le cas echeant, a la vaccination contre le sida
FR2614025B1 (fr) * 1987-04-15 1990-05-18 Pasteur Institut Peptides susceptibles d'etre reconnus par des anticorps induits contre des retrovirus d'immunodeficience humaine (virus hiv) leurs applications au diagnostic des infections dues a certains de ces virus et, le cas echeant, a la vaccination contre le sida
DE3855947T2 (de) * 1987-01-16 1997-12-11 Pasteur Institut Peptide mit den immunologischen Eigenschaften von HIV-2
US6210874B1 (en) 1988-01-27 2001-04-03 Biochem Immunosystems, Inc. Synthetic peptides and mixtures thereof for detecting HIV antibodies
US6197496B1 (en) 1988-06-09 2001-03-06 Institut Pasteur Immunological reagents and diagnostic methods for the detection of human immunodeficiency virus type 2 utilizing multimeric forms of the envelope proteins gp300, p200, and p90/80
US5208321A (en) 1988-06-09 1993-05-04 Institut Pasteur HIV-2 transmembrane glycoprotein homodimer (GP 80)
FR2646854A1 (fr) * 1989-05-12 1990-11-16 Pasteur Institut Antigenes de la glycoproteine transmembranaire d'enveloppe d'un retrovirus humain du type hiv-2 antigenes presentant avec eux une parente immunologique

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8324800D0 (en) * 1983-09-15 1983-10-19 Pasteur Institut Antigens
US4652599A (en) * 1984-04-23 1987-03-24 The United States Of America As Represented By The Department Of Health And Human Services Method of continuous production of retroviruses (HTLV-III) from patients with AIDS and pre-AIDS using permissive cells
US5420113A (en) * 1986-09-12 1995-05-30 Kyowa Hakko Kogyo Co., Ltd. [Leu13]motilin, DNAs coding for same and methods for producing same

Also Published As

Publication number Publication date
JP2865203B2 (ja) 1999-03-08
JPS63502242A (ja) 1988-09-01
FR2593189A1 (fr) 1987-07-24
ZA87469B (en) 1987-09-30

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