FR2596063B1 - Nouveau retrovirus susceptible de provoquer le sida, antigenes obtenus a partir de ce retrovirus et anticorps correspondants et leurs applications au diagnostic du sida - Google Patents

Nouveau retrovirus susceptible de provoquer le sida, antigenes obtenus a partir de ce retrovirus et anticorps correspondants et leurs applications au diagnostic du sida

Info

Publication number
FR2596063B1
FR2596063B1 FR8603881A FR8603881A FR2596063B1 FR 2596063 B1 FR2596063 B1 FR 2596063B1 FR 8603881 A FR8603881 A FR 8603881A FR 8603881 A FR8603881 A FR 8603881A FR 2596063 B1 FR2596063 B1 FR 2596063B1
Authority
FR
France
Prior art keywords
retrovirus
aids
applications
new
corresponding antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8603881A
Other languages
English (en)
Other versions
FR2596063A1 (fr
Inventor
Francoise Brun-Vezinet
Luc Montagnier
Marianne Rey
Christine Rouzioux
Christine Katlama
Solange Chamaret
Denise Guetard
Marc Alizon
Francois Clavel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Pasteur de Lille
Original Assignee
Institut Pasteur de Lille
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut Pasteur de Lille filed Critical Institut Pasteur de Lille
Priority to FR8603881A priority Critical patent/FR2596063B1/fr
Priority to PT84182A priority patent/PT84182B/pt
Priority to EP87400151A priority patent/EP0239425B1/fr
Priority to AU68911/87A priority patent/AU601397B2/en
Priority to PCT/FR1987/000025 priority patent/WO1987004459A1/fr
Priority to AT87400151T priority patent/ATE47725T1/de
Priority to OA59050A priority patent/OA08468A/fr
Priority to DE3752319T priority patent/DE3752319T2/de
Priority to KR1019870700858A priority patent/KR910002428B1/ko
Priority to ES89101328T priority patent/ES2150897T3/es
Priority to DE8787400151T priority patent/DE3760912D1/de
Priority to AR87306572A priority patent/AR243931A1/es
Priority to EP89101328A priority patent/EP0320495B1/fr
Priority to NZ219024A priority patent/NZ219024A/en
Priority to ES87400151T priority patent/ES2013295B3/es
Priority to DE198787400151T priority patent/DE239425T1/de
Priority to AT89101328T priority patent/ATE195148T1/de
Priority to CA000529362A priority patent/CA1338323C/fr
Priority to DK198704934A priority patent/DK175959B1/da
Publication of FR2596063A1 publication Critical patent/FR2596063A1/fr
Priority to GR88300056T priority patent/GR880300056T1/el
Application granted granted Critical
Publication of FR2596063B1 publication Critical patent/FR2596063B1/fr
Priority to GR89400288T priority patent/GR3001096T3/el
Priority to US07/462,908 priority patent/US5066782A/en
Priority to SG285/91A priority patent/SG28591G/en
Priority to HK620/91A priority patent/HK62091A/xx
Priority to US07/810,908 priority patent/US6544728B1/en
Priority to US07/811,150 priority patent/US5976785A/en
Priority to US07/810,824 priority patent/US5306614A/en
Priority to JP5012972A priority patent/JP2611106B2/ja
Priority to US08/214,299 priority patent/US5830641A/en
Priority to US08/214,221 priority patent/US5580739A/en
Priority to US08/250,103 priority patent/US5858651A/en
Priority to JP6329070A priority patent/JPH07233196A/ja
Priority to US08/392,613 priority patent/US6429306B1/en
Priority to US08/470,487 priority patent/US6037165A/en
Priority to US08/468,774 priority patent/US5770703A/en
Priority to US08/468,424 priority patent/US6355789B1/en
Priority to US08/470,491 priority patent/US6265149B1/en
Priority to US08/466,706 priority patent/US6048685A/en
Priority to US08/466,707 priority patent/US6162439A/en
Priority to US08/470,489 priority patent/US7115363B1/en
Priority to JP7257991A priority patent/JP2801162B2/ja
Priority to JP7278085A priority patent/JP2735521B2/ja
Priority to JP8033969A priority patent/JP2874846B2/ja
Priority to JP8193779A priority patent/JP2771519B2/ja
Priority to JP10119235A priority patent/JP2931294B2/ja
Priority to US09/862,029 priority patent/US6518015B1/en
Priority to GR20000402397T priority patent/GR3034708T3/el
Priority to US09/862,511 priority patent/US6664041B2/en
Priority to US09/988,213 priority patent/US20030091985A1/en
Priority to US10/180,460 priority patent/US7341731B2/en
Priority to US10/302,947 priority patent/US20030235835A1/en
Priority to DK200500170A priority patent/DK176253B1/da
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G01N33/56988—HIV or HTLV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/15—Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus, feline leukaemia virus, human T-cell leukaemia-lymphoma virus
    • G01N2333/155—Lentiviridae, e.g. visna-maedi virus, equine infectious virus, FIV, SIV
    • G01N2333/16—HIV-1, HIV-2
    • G01N2333/162—HIV-1, HIV-2 env, e.g. gp160, gp110/120, gp41, V3, peptid T, DC4-Binding site

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Wood Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • AIDS & HIV (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FR8603881A 1986-01-22 1986-03-18 Nouveau retrovirus susceptible de provoquer le sida, antigenes obtenus a partir de ce retrovirus et anticorps correspondants et leurs applications au diagnostic du sida Expired FR2596063B1 (fr)

Priority Applications (52)

Application Number Priority Date Filing Date Title
FR8603881A FR2596063B1 (fr) 1986-03-18 1986-03-18 Nouveau retrovirus susceptible de provoquer le sida, antigenes obtenus a partir de ce retrovirus et anticorps correspondants et leurs applications au diagnostic du sida
PT84182A PT84182B (pt) 1986-01-22 1987-01-22 Novo retrovirus susceptivel de provocar o sida, meios e processos para a sua deteccao "in vitro"
EP87400151A EP0239425B1 (fr) 1986-01-22 1987-01-22 Rétrovirus du type HIV-2 susceptible de provoquer le SIDA, et ses constituants antigéniques et nucléiques
AU68911/87A AU601397B2 (en) 1986-01-22 1987-01-22 Retrovirus of the hiv-2 type susceptible of inducing aids, and its antigenic and nucleic constituents
PCT/FR1987/000025 WO1987004459A1 (fr) 1986-01-22 1987-01-22 Retrovirus du type hiv-2 susceptible de provoquer le sida, et ses constituants antigeniques et nucleiques
AT87400151T ATE47725T1 (de) 1986-01-22 1987-01-22 Zum hervorrufen von aids geeigneter retrovirus vom typ hiv-2, sowie seine antigen- und nukleinsaeure-bestandteile.
OA59050A OA08468A (fr) 1986-01-22 1987-01-22 Retrovirus du type HIV-2 susceptible de provoquer le SIDA et ses constituants antigéniques et nucléiques.
DE3752319T DE3752319T2 (de) 1986-01-22 1987-01-22 Prozess zur rekombinanten Herstellung von HIV-2 - Proteinen sowie Zellen, die HIV-2 - Proteine exprimiert
KR1019870700858A KR910002428B1 (ko) 1986-01-22 1987-01-22 Aids를 유발시킬수 있는 신규 레트로비루스의 제조방법
ES89101328T ES2150897T3 (es) 1986-01-22 1987-01-22 Procedimiento de fabricacion recombinante de las proteinas derivadas de hiv-2 y cultivo celular que expresa proteinas de hiv-2.
DE8787400151T DE3760912D1 (en) 1986-01-22 1987-01-22 Retrovirus of the type hiv-2 capable of inducing aids, and the antigenic and nucleic acid components thereof
AR87306572A AR243931A1 (es) 1986-01-22 1987-01-22 Antigeno purificado,conjunto de reactivos para la deteccion de anticuerpos anti-hiv-2 en un fluido biologico que comprende dichos antigenos,anticuerpos,hibridomas y procedimientos.
EP89101328A EP0320495B1 (fr) 1986-01-22 1987-01-22 Procédé de fabrication récombinante des protéines derivées de HIV-2 et culture cellulaire exprimant des protéines de HIV-2
NZ219024A NZ219024A (en) 1986-01-22 1987-01-22 Hiv-2 retrovirus protein and nucleic acid sequences and detection methods
ES87400151T ES2013295B3 (es) 1986-01-22 1987-01-22 Retrovirus del tipo hiv-2 susceptible de provocar el sida, sus constituyentes antigenicos y nucleicos.
DE198787400151T DE239425T1 (de) 1986-01-22 1987-01-22 Zum hervorrufen von aids geeigneter retrovirus vom typ hiv-2, sowie seine antigen- und nukleinsaeure-bestandteile.
AT89101328T ATE195148T1 (de) 1986-01-22 1987-01-22 Prozess zur rekombinanten herstellung von hiv-2 - proteinen sowie zellen, die hiv-2 - proteine exprimiert
CA000529362A CA1338323C (fr) 1986-02-13 1987-02-10 Retrovirus susceptible de causer le sida, des moyens et des methodes pour le detecter in vitro
DK198704934A DK175959B1 (da) 1986-01-22 1987-09-21 Human HIV-2 retrovirus, der kan fremkalde AIDS, samt fremgangsmåde og middel til påvisning af dettte retrovirus in vitro
GR88300056T GR880300056T1 (en) 1986-01-22 1988-05-20 Retrovirus of the type hiv-2 capable of inducing aids, and the antigenic and nucleic acid components thereof
GR89400288T GR3001096T3 (en) 1986-01-22 1989-12-08 Retrovirus of the type hiv-2 capable of inducing aids, and the antigenic and nucleic acid components thereof
US07/462,908 US5066782A (en) 1986-01-22 1990-01-10 Retrovirus capable of causing AIDS, means and method for detecting it in vitro
SG285/91A SG28591G (en) 1986-01-22 1991-04-22 Retrovirus of the type hiv-2 capable of inducing aids,and the antigenic and nucleic acid components thereof
HK620/91A HK62091A (en) 1986-01-22 1991-08-08 Retrovirus of the type hiv-2 capable of inducing aids,and the antigenic and nucleic acid components thereof
US07/810,908 US6544728B1 (en) 1986-01-22 1991-12-20 Methods and kits for diagnosing human immunodeficiency virus type 2 (HIV-2), proteins of HIV-2, and vaccinating agents for HIV-2
US07/811,150 US5976785A (en) 1986-01-22 1991-12-20 Competitive assays for determining the effectiveness of a human immunodeficiency virus type 2 (HIV-2) antiviral agent, employing peptides and proteins of HIV-2
US07/810,824 US5306614A (en) 1986-01-22 1991-12-20 Methods and kits for diagnosing human immunodeficiency virus type 2(HIV-2)
JP5012972A JP2611106B2 (ja) 1986-01-22 1993-01-28 エイズの原因となる新規なレトロウイルス
US08/214,299 US5830641A (en) 1986-01-22 1994-03-17 In vitro diagnostic assays for the detection of HIV-1 or HIV-2 employing viral-specific antigens and antibodies
US08/214,221 US5580739A (en) 1986-01-22 1994-03-17 Peptides of human immunodeficiency virus type 2 (HIV-2) and in vitro diagnostic methods and kits employing the peptides for the detection of HIV-2
US08/250,103 US5858651A (en) 1986-01-22 1994-05-26 Nucleotide sequences of human immunodeficiency virus type 2 (HIV-2), probes of HIV-2, and methods of using these probes
JP6329070A JPH07233196A (ja) 1986-01-22 1994-12-28 エイズに対するワクチンの有効成分
US08/392,613 US6429306B1 (en) 1986-01-22 1995-02-22 Nucleic acids of a human immunodeficiency virus type 2 (HIV-2)
US08/470,487 US6037165A (en) 1986-01-22 1995-06-06 Methods for the preparation of human immunodeficiency virus type 2 (HIV-2) and antigens encoped thereby
US08/468,774 US5770703A (en) 1986-01-22 1995-06-06 Nucleic acids encoding peptides of the envelope region of HIV-2 and peptides, polypeptides, and methods for producing the peptides and polypeptides of the HIV-2 envelope gene
US08/468,424 US6355789B1 (en) 1986-01-22 1995-06-06 Cloned dna sequences related to the entire genomic rna of human immunodeficiency virus ii (hiv-2), polypeptides encoded by these dna sequences and use of these dna clones and polypeptides in diagnostic kits
US08/470,491 US6265149B1 (en) 1986-01-22 1995-06-06 In vitro diagnostic methods and kits for the detection of HIV-2-specific antibodies
US08/466,706 US6048685A (en) 1986-01-22 1995-06-06 In vitro diagnostic assay employing HIV-2 antigens for the detection of HIV-2 specific antibodies
US08/466,707 US6162439A (en) 1986-01-22 1995-06-06 Human immunodeficiency virus type 2 (HIV-2) polypeptides and methods of producing them
US08/470,489 US7115363B1 (en) 1986-01-22 1995-06-06 Retrovirus capable of causing AIDS, means and methods for detecting it in vitro
JP7257991A JP2801162B2 (ja) 1986-01-22 1995-10-04 エイズの原因となるレトロウイルスに対する抗体
JP7278085A JP2735521B2 (ja) 1986-01-22 1995-10-25 エイズの原因となる新規なレトロウイルスの抗原
JP8033969A JP2874846B2 (ja) 1986-01-22 1996-02-21 エイズの原因となる新規なレトロウイルスに由来する核酸
JP8193779A JP2771519B2 (ja) 1986-01-22 1996-07-23 Ｈｉｖ−２レトロウイルスの回収及び精製方法
JP10119235A JP2931294B2 (ja) 1986-01-22 1998-04-28 エイズの原因となるレトロウイルスに対する抗体を分泌するハイブリドーマ
US09/862,029 US6518015B1 (en) 1986-01-22 2000-05-12 Peptide comprising the sequence CAFRQVC and methods using it
GR20000402397T GR3034708T3 (en) 1986-01-22 2000-10-30 Retrovirus of the type HIV-2 capable of inducing AIDS, and the antigenic and nucleic acid components thereof.
US09/862,511 US6664041B2 (en) 1986-01-22 2001-05-23 Method for preparing a viral extract containing HIV-II RNA
US09/988,213 US20030091985A1 (en) 1986-01-22 2001-11-19 Cloned DNA sequences related to the entire genomic RNA of human immunodeficiency virus II (HIV-2), polypeptides encoded by these DNA sequences and use of these DNA clones and polypeptides in diagnostic kits
US10/180,460 US7341731B2 (en) 1986-01-22 2002-06-27 HIV-2 antigen compositions
US10/302,947 US20030235835A1 (en) 1986-01-22 2002-11-25 Cloned DNA sequences related to the entire genomic RNA of human immunodeficiency virus II (HIV-2), polypeptides encoded by these DNA sequences and use of these DNA clones and polypeptides in diagnostic kits
DK200500170A DK176253B1 (da) 1986-01-22 2005-02-04 Præparat, fremgangsmåde og kit til påvisning af antistoffer mod et humant retrovirus in vitro

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8603881A FR2596063B1 (fr) 1986-03-18 1986-03-18 Nouveau retrovirus susceptible de provoquer le sida, antigenes obtenus a partir de ce retrovirus et anticorps correspondants et leurs applications au diagnostic du sida

Publications (2)

Publication Number Publication Date
FR2596063A1 FR2596063A1 (fr) 1987-09-25
FR2596063B1 true FR2596063B1 (fr) 1989-05-19

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
FR8603881A Expired FR2596063B1 (fr) 1986-01-22 1986-03-18 Nouveau retrovirus susceptible de provoquer le sida, antigenes obtenus a partir de ce retrovirus et anticorps correspondants et leurs applications au diagnostic du sida

Country Status (1)

Country Link
FR (1) FR2596063B1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6210874B1 (en) 1988-01-27 2001-04-03 Biochem Immunosystems, Inc. Synthetic peptides and mixtures thereof for detecting HIV antibodies

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8324800D0 (en) * 1983-09-15 1983-10-19 Pasteur Institut Antigens
US4652599A (en) * 1984-04-23 1987-03-24 The United States Of America As Represented By The Department Of Health And Human Services Method of continuous production of retroviruses (HTLV-III) from patients with AIDS and pre-AIDS using permissive cells

Also Published As

Publication number Publication date
FR2596063A1 (fr) 1987-09-25

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