ES2150897T3 - Procedimiento de fabricacion recombinante de las proteinas derivadas de hiv-2 y cultivo celular que expresa proteinas de hiv-2. - Google Patents
Procedimiento de fabricacion recombinante de las proteinas derivadas de hiv-2 y cultivo celular que expresa proteinas de hiv-2.Info
- Publication number
- ES2150897T3 ES2150897T3 ES89101328T ES89101328T ES2150897T3 ES 2150897 T3 ES2150897 T3 ES 2150897T3 ES 89101328 T ES89101328 T ES 89101328T ES 89101328 T ES89101328 T ES 89101328T ES 2150897 T3 ES2150897 T3 ES 2150897T3
- Authority
- ES
- Spain
- Prior art keywords
- hiv
- proteins
- cell culture
- manufacturing procedure
- expresses
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 208000031886 HIV Infections Diseases 0.000 title abstract 3
- 241000713340 Human immunodeficiency virus 2 Species 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 102000004169 proteins and genes Human genes 0.000 title abstract 3
- 238000004113 cell culture Methods 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000003745 diagnosis Methods 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 108090000288 Glycoproteins Proteins 0.000 abstract 1
- 102000003886 Glycoproteins Human genes 0.000 abstract 1
- 241000725303 Human immunodeficiency virus Species 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 238000009396 hybridization Methods 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000523 sample Substances 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
- G01N33/56988—HIV or HTLV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
- C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
- G01N2333/15—Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus, feline leukaemia virus, human T-cell leukaemia-lymphoma virus
- G01N2333/155—Lentiviridae, e.g. visna-maedi virus, equine infectious virus, FIV, SIV
- G01N2333/16—HIV-1, HIV-2
- G01N2333/162—HIV-1, HIV-2 env, e.g. gp160, gp110/120, gp41, V3, peptid T, DC4-Binding site
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2469/00—Immunoassays for the detection of microorganisms
- G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Communicable Diseases (AREA)
- Urology & Nephrology (AREA)
- Public Health (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
Abstract
LA INVENCION SE REFIERE A UNA NUEVA VARIEDAD DE RETROVIRUS, DENOMINADOS HIV - 2, CUYAS MUESTRAS HAN SIDO DEPOSITADAS EN ECACC BAJO LOS NUMEROS 87.01 1001 Y 87.01 1002 Y EN NCIB BAJO LOS NUMEROS 12398 Y 12399. SE REFIERE TAMBIEN A LOS ANTIGENOS SUSCEPTIBLES DE OBTENERSE A PARTIR DE ESTE VIRUS, EN PARTICULAR DE PROTEINAS P12, P16, P26 Y GP140. ESTOS DIFERENTES ANTIGENOS SON APLICABLES AL DIAGNOSTICVO DE LA ENFERMEDAD, PARTICULARMENTE POR LA PUESTA EN CONTACTO CON UN SERUM DE LA ENFERMEDAD DEL QUE EL DIAGNOSTICO DEBE SER EFECTUADO. SE REFIERE A COMPOSICIONES INMUNOGENICAS CONTENIENDO MAS PARTICULARMENTE LA GLICOPROTEINA SP140. SE REFIERE TAMBIEN A SECUENCIAS NUCLEOTIDICAS, UTILIZABLES PARTICULARMENTE COMO SONDAS DE HIBRIDACION, DERIVADOS DEL ARN DE HIV -2.
Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8600910A FR2593189B1 (fr) | 1986-01-22 | 1986-01-22 | Nouveau retrovirus susceptible de provoquer le sida, antigenes obtenus a partir de ce retrovirus et anticorps correspondants et leurs applications au diagnostic du sida |
FR8600911A FR2593190B1 (fr) | 1986-01-22 | 1986-01-22 | Nouveau retrovirus susceptible de provoquer le sida, antigenes obtenus a partir de ce retrovirus et anticorps correspondants et leurs applications au diagnostic du sida |
FR8601635A FR2593922B1 (fr) | 1986-02-06 | 1986-02-06 | Nouveau retrovirus susceptible de provoquer le sida, antigenes obtenus a partir de ce retrovirus et anticorps correspondants et leurs applications au diagnostic du sida |
FR8601985A FR2594229B1 (fr) | 1986-02-13 | 1986-02-13 | Nouveau retrovirus du type lav-ii susceptible de provoquer le sida, antigenes obtenus a partir de ce retrovirus et anticorps correspondants et leurs applications au diagnostic du sida |
US06/835,228 US4839288A (en) | 1986-01-22 | 1986-03-03 | Retrovirus capable of causing AIDS, antigens obtained from this retrovirus and corresponding antibodies and their application for diagnostic purposes |
FR8603881A FR2596063B1 (fr) | 1986-03-18 | 1986-03-18 | Nouveau retrovirus susceptible de provoquer le sida, antigenes obtenus a partir de ce retrovirus et anticorps correspondants et leurs applications au diagnostic du sida |
FR8604215A FR2597500B1 (fr) | 1986-03-24 | 1986-03-24 | Nouveau retrovirus susceptible de provoquer le sida, antigenes obtenus a partir de ce retrovirus et anticorps correspondants et leurs applications au diagnostic du sida |
US91608086A | 1986-10-06 | 1986-10-06 | |
US93318486A | 1986-11-21 | 1986-11-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2150897T3 true ES2150897T3 (es) | 2000-12-16 |
Family
ID=27576220
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES89101328T Expired - Lifetime ES2150897T3 (es) | 1986-01-22 | 1987-01-22 | Procedimiento de fabricacion recombinante de las proteinas derivadas de hiv-2 y cultivo celular que expresa proteinas de hiv-2. |
Country Status (15)
Country | Link |
---|---|
EP (2) | EP0320495B1 (es) |
JP (7) | JP2611106B2 (es) |
AR (1) | AR243931A1 (es) |
AT (2) | ATE47725T1 (es) |
AU (1) | AU601397B2 (es) |
DE (3) | DE3760912D1 (es) |
DK (2) | DK175959B1 (es) |
ES (1) | ES2150897T3 (es) |
GR (3) | GR880300056T1 (es) |
HK (1) | HK62091A (es) |
NZ (1) | NZ219024A (es) |
OA (1) | OA08468A (es) |
PT (1) | PT84182B (es) |
SG (1) | SG28591G (es) |
WO (1) | WO1987004459A1 (es) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0249611A4 (en) * | 1985-11-14 | 1988-04-26 | Harvard College | T-LYMPHOTROPHIC VIRUS. |
EP0750041B1 (fr) * | 1987-01-16 | 2008-12-10 | Institut Pasteur | Séquences de nucléotides de HIV-2 et SIV-1 |
DE3855947T2 (de) * | 1987-01-16 | 1997-12-11 | Pasteur Institut | Peptide mit den immunologischen Eigenschaften von HIV-2 |
AU620804B2 (en) * | 1987-03-23 | 1992-02-27 | Hiver Limited | Novel vaccines |
SE8701765L (sv) * | 1987-04-28 | 1988-10-29 | Statens Bakteriologiska Lab | Analysmetod och medel foer denna |
US4812556A (en) * | 1987-05-18 | 1989-03-14 | Virovahl | Synthetic peptide antigen for the detection of HIV-2 infection |
FR2620030B1 (fr) * | 1987-09-07 | 1990-03-23 | Transgene Sa | Vecteur d'expression des proteines du virus hiv-2, un agent causal du sida, culture cellulaire infectee ou transformee par ce vecteur, proteines obtenues, vaccin et anticorps obtenus |
US5780038A (en) * | 1987-11-16 | 1998-07-14 | Roche Diagnostic Systems, Inc. | HIV-2 envelope polypeptides |
ATE87487T1 (de) * | 1987-11-16 | 1993-04-15 | Hoffmann La Roche | Rekombinante hiv-2 polypeptide. |
WO1989006276A2 (en) * | 1988-01-08 | 1989-07-13 | Dpz Deutsches Primatenzentrum Gesellschaft Mbh | Hiv-2-type retroviruses of primates, vaccines, diagnostic and pharmaceutical compositions |
US6210874B1 (en) | 1988-01-27 | 2001-04-03 | Biochem Immunosystems, Inc. | Synthetic peptides and mixtures thereof for detecting HIV antibodies |
WO1989009815A1 (en) * | 1988-04-04 | 1989-10-19 | Research Corporation Technologies, Inc. | Novel virus of the hiv-2 family and methods of detection therefor |
US6197496B1 (en) | 1988-06-09 | 2001-03-06 | Institut Pasteur | Immunological reagents and diagnostic methods for the detection of human immunodeficiency virus type 2 utilizing multimeric forms of the envelope proteins gp300, p200, and p90/80 |
EP1369427A3 (en) * | 1988-06-09 | 2004-05-12 | Innogenetics N.V. | HIV-3 retrovirus strains and their use |
US5208321A (en) | 1988-06-09 | 1993-05-04 | Institut Pasteur | HIV-2 transmembrane glycoprotein homodimer (GP 80) |
EP0345559A3 (en) * | 1988-06-10 | 1990-07-11 | Abbott Laboratories | Hiv-2 variants |
DE68927025T2 (de) † | 1988-06-14 | 1997-03-27 | Qiagen Gmbh | HIV-2-Virusvarianten |
ATE136789T1 (de) * | 1989-05-12 | 1996-05-15 | Pasteur Institut | Antigene eines transmembranen hüllenglycoproteins eines menschlichen retrovirus des typs hiv-2 und immunologisch verwandte antigene |
FR2646854A1 (fr) * | 1989-05-12 | 1990-11-16 | Pasteur Institut | Antigenes de la glycoproteine transmembranaire d'enveloppe d'un retrovirus humain du type hiv-2 antigenes presentant avec eux une parente immunologique |
DE68925202T2 (de) * | 1989-05-31 | 1996-06-05 | Pasteur Institut | HIV-2-EHO-Retrovirus-Proteine und -Glycoproteine, Antikörper gegen sie, Verwendung für diagnostische Zwecke |
ES2275451T3 (es) * | 1989-06-02 | 2009-02-16 | Institut Pasteur | Secuencias nucleotidicas procedentes del genoma de los retrovirus del tipo vih-1,vih-2 y siv, y sus aplicaciones especialmente para la amplificacion de los genomas de estos retrovirus y para el diagnostico in vitro de las infecciones debidas a estos virus. |
FR2647810B1 (fr) * | 1989-06-02 | 1994-07-22 | Pasteur Institut | Amorces oligonucleotidiques pour l'amplification du genome des retrovirus du type hiv-2 et siv, et leurs applications au diagnostic in vitro des infections dues a ces virus |
FR2647809B1 (fr) * | 1989-06-02 | 1991-09-20 | Pasteur Institut | Amorces oligonucleotidiques pour l'amplification du genome des retrovirus du type hiv-1, hiv-2 et siv, et leurs applications au diagnostic in vitro des infections dues a ces virus |
US7022814B1 (en) | 1992-01-21 | 2006-04-04 | Institut Pasteur And Institut National De La Sante Et De La Recherche Medicale | Nucleotide sequences derived from the genome of retroviruses of the HIV-1, HIV-2 and SIV type, and their uses in particular for the amplification of the genomes of these retroviruses and for the in vitro diagnosis of the diseases due to these viruses |
FR2657016B1 (fr) * | 1990-01-16 | 1995-08-25 | Clonatec Sa | Peptides derivant de la glycoproteine d'enveloppe du virus-hiv-2, leurs applications a la detection d'une infection due a ce virus et a la vaccination contre le sida. |
EP0438332B1 (fr) * | 1990-01-16 | 1998-04-08 | Orgenics Ltd. | Peptides dérivant de la glycoprotéine d'enveloppe de virus HIV, leurs applications à la détection d'une infection due à ces virus et à la vaccination contre le SIDA |
ATE105857T1 (de) | 1990-06-15 | 1994-06-15 | Innogenetics Nv | Siv cpz-ant retrovirus und seine anwendungen. |
GB9108652D0 (en) * | 1991-04-23 | 1991-06-12 | Antisoma Ltd | Immunoreactive compounds |
CA2107732C (en) * | 1992-10-06 | 2003-04-08 | Lutz G. Gurtler | Retrovirus from the hiv group and its use |
DE4233646C2 (de) * | 1992-10-06 | 2003-10-23 | Dade Behring Marburg Gmbh | Retrovirus aus der HIV-Gruppe und dessen Verwendung |
DE4405810A1 (de) | 1994-02-23 | 1995-08-24 | Behringwerke Ag | Von einem Retrovirus aus der HIV-Gruppe abgeleitete Peptide und deren Verwendung |
US5962665A (en) * | 1997-06-16 | 1999-10-05 | Abbott Laboratories | Nucleic acid primers and probes for detecting HIV-1 and HIV-2 |
FR2767337B1 (fr) | 1997-08-14 | 2002-07-05 | Pasteur Institut | Sequences nucleiques de polypeptides exportes de mycobacteri es, vecteurs les comprenant et applications au diagnostic et a la prevention de la tuberculose |
CA2422956C (en) | 2000-10-23 | 2010-10-19 | Gen-Probe Incorporated | Compositions and methods for detecting human immunodeficiency virus 2 (hiv-2) |
CA2547750C (en) | 2003-12-19 | 2014-04-08 | Gen-Probe Incorporated | Compositions, methods and kits for detecting the nucleic acids of hiv-1 and hiv-2 |
JP6721772B1 (ja) | 2019-03-26 | 2020-07-15 | 斉藤 幹雄 | 清掃装置 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4652599A (en) * | 1984-04-23 | 1987-03-24 | The United States Of America As Represented By The Department Of Health And Human Services | Method of continuous production of retroviruses (HTLV-III) from patients with AIDS and pre-AIDS using permissive cells |
ATE250083T1 (de) * | 1984-10-18 | 2003-10-15 | Pasteur Institut | Lav-antigene und -peptide |
US4600413A (en) * | 1984-12-10 | 1986-07-15 | Sundstrand Corporation | Centrifugal deaerator and pump |
JP3105581B2 (ja) * | 1991-07-03 | 2000-11-06 | 内橋エステック株式会社 | 面状温度ヒュ−ズ |
-
1987
- 1987-01-22 AU AU68911/87A patent/AU601397B2/en not_active Expired
- 1987-01-22 AT AT87400151T patent/ATE47725T1/de not_active IP Right Cessation
- 1987-01-22 OA OA59050A patent/OA08468A/xx unknown
- 1987-01-22 DE DE8787400151T patent/DE3760912D1/de not_active Expired
- 1987-01-22 AR AR87306572A patent/AR243931A1/es active
- 1987-01-22 EP EP89101328A patent/EP0320495B1/fr not_active Expired - Lifetime
- 1987-01-22 WO PCT/FR1987/000025 patent/WO1987004459A1/fr unknown
- 1987-01-22 DE DE198787400151T patent/DE239425T1/de active Pending
- 1987-01-22 AT AT89101328T patent/ATE195148T1/de not_active IP Right Cessation
- 1987-01-22 ES ES89101328T patent/ES2150897T3/es not_active Expired - Lifetime
- 1987-01-22 DE DE3752319T patent/DE3752319T2/de not_active Expired - Lifetime
- 1987-01-22 PT PT84182A patent/PT84182B/pt unknown
- 1987-01-22 EP EP87400151A patent/EP0239425B1/fr not_active Expired
- 1987-01-22 NZ NZ219024A patent/NZ219024A/en unknown
- 1987-09-21 DK DK198704934A patent/DK175959B1/da not_active IP Right Cessation
-
1988
- 1988-05-20 GR GR88300056T patent/GR880300056T1/el unknown
-
1989
- 1989-12-08 GR GR89400288T patent/GR3001096T3/el unknown
-
1991
- 1991-04-22 SG SG285/91A patent/SG28591G/en unknown
- 1991-08-08 HK HK620/91A patent/HK62091A/xx not_active IP Right Cessation
-
1993
- 1993-01-28 JP JP5012972A patent/JP2611106B2/ja not_active Expired - Lifetime
-
1994
- 1994-12-28 JP JP6329070A patent/JPH07233196A/ja active Pending
-
1995
- 1995-10-04 JP JP7257991A patent/JP2801162B2/ja not_active Expired - Lifetime
- 1995-10-25 JP JP7278085A patent/JP2735521B2/ja not_active Expired - Lifetime
-
1996
- 1996-02-21 JP JP8033969A patent/JP2874846B2/ja not_active Expired - Lifetime
- 1996-07-23 JP JP8193779A patent/JP2771519B2/ja not_active Expired - Lifetime
-
1998
- 1998-04-28 JP JP10119235A patent/JP2931294B2/ja not_active Expired - Lifetime
-
2000
- 2000-10-30 GR GR20000402397T patent/GR3034708T3/el not_active IP Right Cessation
-
2005
- 2005-02-04 DK DK200500170A patent/DK176253B1/da not_active IP Right Cessation
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