DE3789309D1 - Enzymatische membran, verfahren zur herstellung und trennung von peptiden. - Google Patents

Enzymatische membran, verfahren zur herstellung und trennung von peptiden.

Info

Publication number
DE3789309D1
DE3789309D1 DE87905545T DE3789309T DE3789309D1 DE 3789309 D1 DE3789309 D1 DE 3789309D1 DE 87905545 T DE87905545 T DE 87905545T DE 3789309 T DE3789309 T DE 3789309T DE 3789309 D1 DE3789309 D1 DE 3789309D1
Authority
DE
Germany
Prior art keywords
peptides
separation
production
enzymatic membrane
enzymatic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE87905545T
Other languages
English (en)
Other versions
DE3789309T2 (de
Inventor
Guillermo Iacobucci
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Coca Cola Co
Original Assignee
Coca Cola Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/897,679 external-priority patent/US5037741A/en
Application filed by Coca Cola Co filed Critical Coca Cola Co
Application granted granted Critical
Publication of DE3789309D1 publication Critical patent/DE3789309D1/de
Publication of DE3789309T2 publication Critical patent/DE3789309T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/813—Continuous fermentation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/819—Fermentation vessels in series
DE3789309T 1986-08-18 1987-08-14 Enzymatische membran, verfahren zur herstellung und trennung von peptiden. Expired - Fee Related DE3789309T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US06/897,679 US5037741A (en) 1986-08-18 1986-08-18 Enzymatic method for the synthesis and separation of peptides
US07/078,504 US5002871A (en) 1986-08-18 1987-07-28 Enzymatic membrane method for the synthesis and separation of peptides
PCT/US1987/002030 WO1988001298A2 (en) 1986-08-18 1987-08-14 Enzymatic membrane method for the synthesis and separation of peptides

Publications (2)

Publication Number Publication Date
DE3789309D1 true DE3789309D1 (de) 1994-04-14
DE3789309T2 DE3789309T2 (de) 1994-10-06

Family

ID=26760616

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3789309T Expired - Fee Related DE3789309T2 (de) 1986-08-18 1987-08-14 Enzymatische membran, verfahren zur herstellung und trennung von peptiden.

Country Status (22)

Country Link
US (1) US5002871A (de)
EP (1) EP0321479B1 (de)
JP (1) JPH06319592A (de)
KR (1) KR900004070B1 (de)
CN (1) CN1026498C (de)
AR (1) AR242264A1 (de)
AT (1) ATE102654T1 (de)
AU (1) AU610520B2 (de)
DE (1) DE3789309T2 (de)
DK (1) DK209388A (de)
EG (1) EG18454A (de)
ES (1) ES2007103A6 (de)
FI (1) FI884359A (de)
GB (1) GB2218991B (de)
GR (1) GR871290B (de)
IL (2) IL83564A (de)
MX (1) MX168598B (de)
NZ (2) NZ231657A (de)
PH (1) PH26764A (de)
PT (1) PT85548B (de)
SG (1) SG35491G (de)
WO (1) WO1988001298A2 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5244791A (en) * 1984-05-29 1993-09-14 Genecor International, Inc. Methods of ester hydrolysis
US5055399A (en) * 1985-01-15 1991-10-08 Genentech, Inc. Enzymatic synthesis of alpha-L-aspartyl-L-phenyalanine lower alkyl esters
US5202235A (en) * 1986-08-18 1993-04-13 The Coca-Cola Company Enzymatic method for the synthesis and separation of peptides
US5336601A (en) * 1986-08-18 1994-08-09 The Coca-Cola Company Enzymatic membrane method for the snythesis and separation of peptides
US5350681A (en) * 1986-08-18 1994-09-27 The Coca-Cola Company Enzymatic membrane method for the synthesis and separation of peptides
US4800162A (en) * 1987-04-01 1989-01-24 Sepracor, Inc. Method for resolution of steroisomers in multiphase and extractive membrane reactors
JPH04502558A (ja) * 1989-04-24 1992-05-14 ザ・コカ―コーラ・カンパニー ペプチドの合成および分離の酵素膜方法
US5314807A (en) * 1991-03-29 1994-05-24 Nippon Gohsei Kagaku Kogyo Kabushiki Kaisha Method for producing an angiotensin converting enzyme inhibitor-containing composition
IL101573A0 (en) * 1991-04-12 1992-12-30 Philadelphia Children Hospital Endopeptidase
WO1998033581A1 (de) * 1997-02-04 1998-08-06 Akzo Nobel N.V. Membranmodul enthaltend mindestens zwei gruppen von hohlfasermembranen und verfahren zu seiner herstellung
FR2777803B1 (fr) * 1998-04-24 2000-07-28 Univ Claude Bernard Lyon Procede d'elimination active et selective de petites molecules par pompage enzymatique : dialyse active
US6500571B2 (en) * 1998-08-19 2002-12-31 Powerzyme, Inc. Enzymatic fuel cell
JP2003534113A (ja) * 2000-04-21 2003-11-18 ユニバーシティー オブ ロチェスター 二相性反応容器および使用法
US6485650B1 (en) * 2000-08-28 2002-11-26 Facilichem, Inc. Liquid membrane separation of enantiomers
US20020114906A1 (en) * 2000-11-20 2002-08-22 Bridgestone Corporation Base body for photosensitive drum and photosensitive drum using the same

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE454512A (de) * 1943-02-23
US3625734A (en) * 1969-10-16 1971-12-07 Usa Ultra-thin liquid membrane construction
US3779907A (en) * 1970-04-13 1973-12-18 Exxon Research Engineering Co Liquid membrane process for the separation of aqueous mixtures
CA947214A (en) * 1971-04-02 1974-05-14 Antoine D'iorio Resolution of racemates of ring-substituted phenylalanines
US3933781A (en) * 1973-11-05 1976-01-20 Monsanto Company Process for the preparation of α-L-aspartyl-L-phenylalanine alkyl esters
US4119493A (en) * 1975-10-23 1978-10-10 (Zaidanhojin) Sagami Chemical Research Center Process for producing a peptide
DE2804892A1 (de) * 1977-02-09 1978-08-10 Procter & Gamble Verfahren zur herstellung von l-threonin und dessen n-acylderivat
US4187086A (en) * 1977-06-15 1980-02-05 General Electric Company Packaged membrane system and replenishment method
US4119408A (en) * 1977-06-22 1978-10-10 General Electric Company Apparatus for maintaining the separation efficiency of immobilized liquid membranes in gas separation
US4251631A (en) * 1978-02-23 1981-02-17 Research Products Rehovot Ltd. Cross-linked enzyme membrane
GB2047564B (en) * 1978-03-27 1983-01-26 Bend Res Inc Separator membrane and process using such membrane for removing ions from an aqueous solution
DE2907450A1 (de) * 1979-02-26 1980-09-04 Rehovot Res Prod Verfahren zur trennung eines waessrigen loesungsgemisches durch elektrodialyse
JPS6339237B2 (de) * 1979-04-06 1988-08-04 Karuruberugu Baiotekunorojii Ltd As
EP0075160B1 (de) * 1981-09-21 1987-01-07 Toyo Soda Manufacturing Co., Ltd. Verfahren zur Gewinnung eines Dipeptidderivates
US4455210A (en) * 1982-03-04 1984-06-19 General Electric Company Multi layer ion exchanging membrane with protected interior hydroxyl ion rejection layer
JPS59183825A (ja) * 1983-04-04 1984-10-19 Nippon Oil & Fats Co Ltd 不均一系反応方法
DE3479214D1 (en) * 1983-04-28 1989-09-07 Ajinomoto Kk Process for the production of l-aspartyl-l-phenylalanine methyl ester or l-aspartyl-l-phenylalanine
JPS60164495A (ja) * 1984-01-16 1985-08-27 モンサント　コンパニー Ｎ‐ホルミルアミノ酸とペプチド残基の酵素的結合法
DE3438189A1 (de) * 1984-10-18 1986-04-24 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung aromatisch substituierter l-aminosaeuren
AU598452B2 (en) * 1985-01-15 1990-06-28 Genentech Inc. Method and apparatus for enzymatic synthesis
US4743547A (en) * 1985-04-09 1988-05-10 Kuraray Co., Ltd. Method of producing L-phenylalanine

Also Published As

Publication number Publication date
AU610520B2 (en) 1991-05-23
NZ231657A (en) 1991-07-26
AU7854387A (en) 1988-03-08
GB8903271D0 (en) 1989-08-23
NZ221467A (en) 1990-07-26
IL83564A (en) 1992-03-29
KR900004070B1 (ko) 1990-06-11
PT85548B (pt) 1990-05-31
SG35491G (en) 1991-06-21
EP0321479A1 (de) 1989-06-28
DK209388D0 (da) 1988-04-15
PT85548A (en) 1987-09-01
CN1026498C (zh) 1994-11-09
FI884359A0 (fi) 1988-09-22
GR871290B (en) 1987-12-23
WO1988001298A2 (en) 1988-02-25
GB2218991B (en) 1991-02-13
ES2007103A6 (es) 1989-06-01
EP0321479B1 (de) 1994-03-09
JPH06319592A (ja) 1994-11-22
DE3789309T2 (de) 1994-10-06
US5002871A (en) 1991-03-26
FI884359A (fi) 1988-09-22
IL83564A0 (en) 1988-01-31
KR880701778A (ko) 1988-11-05
PH26764A (en) 1992-09-28
GB2218991A (en) 1989-11-29
MX168598B (es) 1993-06-01
IL98061A (en) 1992-03-29
AR242264A1 (es) 1993-03-31
CN87106791A (zh) 1988-05-04
EG18454A (en) 1994-10-30
ATE102654T1 (de) 1994-03-15
WO1988001298A3 (en) 1988-04-07
DK209388A (da) 1988-04-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee