IL98061A - Method for the enzymatic resolution of racemic carboxylic acid compounds - Google Patents

Method for the enzymatic resolution of racemic carboxylic acid compounds

Info

Publication number
IL98061A
IL98061A IL98061A IL9806187A IL98061A IL 98061 A IL98061 A IL 98061A IL 98061 A IL98061 A IL 98061A IL 9806187 A IL9806187 A IL 9806187A IL 98061 A IL98061 A IL 98061A
Authority
IL
Israel
Prior art keywords
carboxylic acid
acid compounds
enzymatic resolution
racemic carboxylic
racemic
Prior art date
Application number
IL98061A
Other languages
English (en)
Original Assignee
Coca Cola Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/897,679 external-priority patent/US5037741A/en
Application filed by Coca Cola Co filed Critical Coca Cola Co
Publication of IL98061A publication Critical patent/IL98061A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/813—Continuous fermentation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/819—Fermentation vessels in series

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
IL98061A 1986-08-18 1987-08-17 Method for the enzymatic resolution of racemic carboxylic acid compounds IL98061A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US06/897,679 US5037741A (en) 1986-08-18 1986-08-18 Enzymatic method for the synthesis and separation of peptides
US07/078,504 US5002871A (en) 1986-08-18 1987-07-28 Enzymatic membrane method for the synthesis and separation of peptides
IL83564A IL83564A (en) 1986-08-18 1987-08-17 Enzymatic membrane method for the synthesis and separation of l,l-di-peptides

Publications (1)

Publication Number Publication Date
IL98061A true IL98061A (en) 1992-03-29

Family

ID=26760616

Family Applications (2)

Application Number Title Priority Date Filing Date
IL83564A IL83564A (en) 1986-08-18 1987-08-17 Enzymatic membrane method for the synthesis and separation of l,l-di-peptides
IL98061A IL98061A (en) 1986-08-18 1987-08-17 Method for the enzymatic resolution of racemic carboxylic acid compounds

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL83564A IL83564A (en) 1986-08-18 1987-08-17 Enzymatic membrane method for the synthesis and separation of l,l-di-peptides

Country Status (22)

Country Link
US (1) US5002871A (xx)
EP (1) EP0321479B1 (xx)
JP (1) JPH06319592A (xx)
KR (1) KR900004070B1 (xx)
CN (1) CN1026498C (xx)
AR (1) AR242264A1 (xx)
AT (1) ATE102654T1 (xx)
AU (1) AU610520B2 (xx)
DE (1) DE3789309T2 (xx)
DK (1) DK209388D0 (xx)
EG (1) EG18454A (xx)
ES (1) ES2007103A6 (xx)
FI (1) FI884359A (xx)
GB (1) GB2218991B (xx)
GR (1) GR871290B (xx)
IL (2) IL83564A (xx)
MX (1) MX168598B (xx)
NZ (2) NZ231657A (xx)
PH (1) PH26764A (xx)
PT (1) PT85548B (xx)
SG (1) SG35491G (xx)
WO (1) WO1988001298A2 (xx)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5244791A (en) * 1984-05-29 1993-09-14 Genecor International, Inc. Methods of ester hydrolysis
US5055399A (en) * 1985-01-15 1991-10-08 Genentech, Inc. Enzymatic synthesis of alpha-L-aspartyl-L-phenyalanine lower alkyl esters
US5336601A (en) * 1986-08-18 1994-08-09 The Coca-Cola Company Enzymatic membrane method for the snythesis and separation of peptides
US5350681A (en) * 1986-08-18 1994-09-27 The Coca-Cola Company Enzymatic membrane method for the synthesis and separation of peptides
US5202235A (en) * 1986-08-18 1993-04-13 The Coca-Cola Company Enzymatic method for the synthesis and separation of peptides
US4800162A (en) * 1987-04-01 1989-01-24 Sepracor, Inc. Method for resolution of steroisomers in multiphase and extractive membrane reactors
EP0470175A1 (en) * 1989-04-24 1992-02-12 The Coca-Cola Company Enzymatic membrane method for the synthesis and separation of peptides
US5314807A (en) * 1991-03-29 1994-05-24 Nippon Gohsei Kagaku Kogyo Kabushiki Kaisha Method for producing an angiotensin converting enzyme inhibitor-containing composition
EP0533913A1 (en) * 1991-04-12 1993-03-31 The Children's Hospital Of Philadelphia Novel endopeptidase
EP0963239B1 (de) * 1997-02-04 2002-07-31 MAT Adsorption Technologies GmbH & Co. KG Membranmodul enthaltend mindestens zwei gruppen von hohlfasermembranen und verfahren zu seiner herstellung
FR2777803B1 (fr) * 1998-04-24 2000-07-28 Univ Claude Bernard Lyon Procede d'elimination active et selective de petites molecules par pompage enzymatique : dialyse active
US6500571B2 (en) 1998-08-19 2002-12-31 Powerzyme, Inc. Enzymatic fuel cell
US6599754B2 (en) * 2000-04-21 2003-07-29 University Of Rochester Biphasic reaction vessel and methods of use
US6485650B1 (en) * 2000-08-28 2002-11-26 Facilichem, Inc. Liquid membrane separation of enantiomers
US20020114906A1 (en) * 2000-11-20 2002-08-22 Bridgestone Corporation Base body for photosensitive drum and photosensitive drum using the same
CN116813711B (zh) * 2023-03-24 2024-02-27 周志图 降血糖抗氧化的菊芋肽、其制备方法及其应用

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE454512A (xx) * 1943-02-23
US3625734A (en) * 1969-10-16 1971-12-07 Usa Ultra-thin liquid membrane construction
US3779907A (en) * 1970-04-13 1973-12-18 Exxon Research Engineering Co Liquid membrane process for the separation of aqueous mixtures
CA947214A (en) * 1971-04-02 1974-05-14 Antoine D'iorio Resolution of racemates of ring-substituted phenylalanines
US3933781A (en) * 1973-11-05 1976-01-20 Monsanto Company Process for the preparation of α-L-aspartyl-L-phenylalanine alkyl esters
US4119493A (en) * 1975-10-23 1978-10-10 (Zaidanhojin) Sagami Chemical Research Center Process for producing a peptide
DE2804892A1 (de) * 1977-02-09 1978-08-10 Procter & Gamble Verfahren zur herstellung von l-threonin und dessen n-acylderivat
US4187086A (en) * 1977-06-15 1980-02-05 General Electric Company Packaged membrane system and replenishment method
US4119408A (en) * 1977-06-22 1978-10-10 General Electric Company Apparatus for maintaining the separation efficiency of immobilized liquid membranes in gas separation
US4251631A (en) * 1978-02-23 1981-02-17 Research Products Rehovot Ltd. Cross-linked enzyme membrane
GB2047564B (en) * 1978-03-27 1983-01-26 Bend Res Inc Separator membrane and process using such membrane for removing ions from an aqueous solution
DE2907450A1 (de) * 1979-02-26 1980-09-04 Rehovot Res Prod Verfahren zur trennung eines waessrigen loesungsgemisches durch elektrodialyse
JPS6339237B2 (xx) * 1979-04-06 1988-08-04 Karuruberugu Baiotekunorojii Ltd As
DE3274985D1 (en) * 1981-09-21 1987-02-12 Toyo Soda Mfg Co Ltd Process for recovering a dipeptide derivative
US4455210A (en) * 1982-03-04 1984-06-19 General Electric Company Multi layer ion exchanging membrane with protected interior hydroxyl ion rejection layer
JPS59183825A (ja) * 1983-04-04 1984-10-19 Nippon Oil & Fats Co Ltd 不均一系反応方法
DE3479214D1 (en) * 1983-04-28 1989-09-07 Ajinomoto Kk Process for the production of l-aspartyl-l-phenylalanine methyl ester or l-aspartyl-l-phenylalanine
JPS60164495A (ja) * 1984-01-16 1985-08-27 モンサント　コンパニー Ｎ‐ホルミルアミノ酸とペプチド残基の酵素的結合法
DE3438189A1 (de) * 1984-10-18 1986-04-24 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung aromatisch substituierter l-aminosaeuren
ATE76096T1 (de) * 1985-01-15 1992-05-15 Genentech Inc Verfahren und vorrichtung fuer enzymatische synthese.
US4743547A (en) * 1985-04-09 1988-05-10 Kuraray Co., Ltd. Method of producing L-phenylalanine

Also Published As

Publication number Publication date
EP0321479A1 (en) 1989-06-28
PT85548B (pt) 1990-05-31
EP0321479B1 (en) 1994-03-09
AR242264A1 (es) 1993-03-31
GB2218991A (en) 1989-11-29
DE3789309D1 (de) 1994-04-14
EG18454A (en) 1994-10-30
PT85548A (en) 1987-09-01
AU7854387A (en) 1988-03-08
NZ231657A (en) 1991-07-26
NZ221467A (en) 1990-07-26
GB2218991B (en) 1991-02-13
DE3789309T2 (de) 1994-10-06
AU610520B2 (en) 1991-05-23
GR871290B (en) 1987-12-23
IL83564A0 (en) 1988-01-31
WO1988001298A2 (en) 1988-02-25
DK209388A (da) 1988-04-15
GB8903271D0 (en) 1989-08-23
CN1026498C (zh) 1994-11-09
JPH06319592A (ja) 1994-11-22
CN87106791A (zh) 1988-05-04
MX168598B (es) 1993-06-01
PH26764A (en) 1992-09-28
SG35491G (en) 1991-06-21
ES2007103A6 (es) 1989-06-01
KR900004070B1 (ko) 1990-06-11
ATE102654T1 (de) 1994-03-15
FI884359A0 (fi) 1988-09-22
KR880701778A (ko) 1988-11-05
FI884359A (fi) 1988-09-22
IL83564A (en) 1992-03-29
US5002871A (en) 1991-03-26
WO1988001298A3 (en) 1988-04-07
DK209388D0 (da) 1988-04-15

Similar Documents

Publication Publication Date Title
IL98061A (en) Method for the enzymatic resolution of racemic carboxylic acid compounds
DE3666420D1 (en) Method for the production of carboxylic acids
PT80621A (en) Process for preparing carboxylic acid ester derivatives of deglucoteicoplanin
EP0266691A3 (en) Method for the production of alkene carboxylic acid esters
AR243509A1 (es) Metodo de obtencion del acido quinoloncarboxilico.
IL81318A0 (en) Method of working up the solution from the enzymatic resolution of a racemate of an n-acetyl-dl-amino carboxylic acid
EP0165070A3 (en) Method for racemization of chrysanthemic acid or its ester
GB8630759D0 (en) Carboxylic acid derivatives
DE3469437D1 (en) Process for the optical resolution of racemic mixtures of alpha-naphthyl-propionic acids
DE3565397D1 (en) Method for racemization of chrysanthemic acid or its ester
HUT43993A (en) Process for racemization of chrisantheme acid or its esthers
PH24285A (en) A process for the manufacture of carboxylic acid amides
IL98061A0 (en) Method for the enzymatic resolution of racemic carboxylic acid compounds
DE3572346D1 (en) Process for the preparation of carboxylic acid esters of hydroxy sulfonates
EP0286981A3 (en) Method for the production of carboxylic acid methyl esters
EP0252736A3 (en) Process for preparing fluorine-containing carboxylic acid ester
DE3563349D1 (en) Process for the preparation of a carboxylic acid
EP0252408A3 (en) Method for the production of carboxylic acid halides
DE3665569D1 (en) Process for the racemic resolution of d,l-2-aminobutan-1-ol
PL268197A1 (en) Method for manufacturing new 1-cyclopropyl-quinoline carboxylic acid salts
DE3375478D1 (en) Method for the resolution of racemic 2-cp-difluoromethoxy phenyl)-3-methylbutyric acid
DE3660543D1 (en) Process for the preparation of aspartic acid 4-benzyl ester
IE872185L (en) Enzymatic synthesis of peptides- enzymatic resolution of¹racemic carboxylic acid compounds
GB2181732B (en) Process for the preparation of 2e 4e carboxylic acids
BG43917A1 (en) Method for preparing of racemic 3- brom- 2- methyl propionic acid