ATE102654T1 - Enzymatische membran, verfahren zur herstellung und trennung von peptiden. - Google Patents

Enzymatische membran, verfahren zur herstellung und trennung von peptiden.

Info

Publication number
ATE102654T1
ATE102654T1 AT87905545T AT87905545T ATE102654T1 AT E102654 T1 ATE102654 T1 AT E102654T1 AT 87905545 T AT87905545 T AT 87905545T AT 87905545 T AT87905545 T AT 87905545T AT E102654 T1 ATE102654 T1 AT E102654T1
Authority
AT
Austria
Prior art keywords
peptides
separation
preparation
enzymatic membrane
enzymatic
Prior art date
Application number
AT87905545T
Other languages
English (en)
Inventor
Guillermo A Iacobucci
Original Assignee
Coca Cola Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/897,679 external-priority patent/US5037741A/en
Application filed by Coca Cola Co filed Critical Coca Cola Co
Application granted granted Critical
Publication of ATE102654T1 publication Critical patent/ATE102654T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/813—Continuous fermentation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/819—Fermentation vessels in series

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AT87905545T 1986-08-18 1987-08-14 Enzymatische membran, verfahren zur herstellung und trennung von peptiden. ATE102654T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US06/897,679 US5037741A (en) 1986-08-18 1986-08-18 Enzymatic method for the synthesis and separation of peptides
US07/078,504 US5002871A (en) 1986-08-18 1987-07-28 Enzymatic membrane method for the synthesis and separation of peptides
PCT/US1987/002030 WO1988001298A2 (en) 1986-08-18 1987-08-14 Enzymatic membrane method for the synthesis and separation of peptides
EP87905545A EP0321479B1 (de) 1986-08-18 1987-08-14 Enzymatische membran, verfahren zur herstellung und trennung von peptiden

Publications (1)

Publication Number Publication Date
ATE102654T1 true ATE102654T1 (de) 1994-03-15

Family

ID=26760616

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87905545T ATE102654T1 (de) 1986-08-18 1987-08-14 Enzymatische membran, verfahren zur herstellung und trennung von peptiden.

Country Status (22)

Country Link
US (1) US5002871A (de)
EP (1) EP0321479B1 (de)
JP (1) JPH06319592A (de)
KR (1) KR900004070B1 (de)
CN (1) CN1026498C (de)
AR (1) AR242264A1 (de)
AT (1) ATE102654T1 (de)
AU (1) AU610520B2 (de)
DE (1) DE3789309T2 (de)
DK (1) DK209388D0 (de)
EG (1) EG18454A (de)
ES (1) ES2007103A6 (de)
FI (1) FI884359A0 (de)
GB (1) GB2218991B (de)
GR (1) GR871290B (de)
IL (2) IL98061A (de)
MX (1) MX168598B (de)
NZ (2) NZ221467A (de)
PH (1) PH26764A (de)
PT (1) PT85548B (de)
SG (1) SG35491G (de)
WO (1) WO1988001298A2 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5244791A (en) * 1984-05-29 1993-09-14 Genecor International, Inc. Methods of ester hydrolysis
US5055399A (en) * 1985-01-15 1991-10-08 Genentech, Inc. Enzymatic synthesis of alpha-L-aspartyl-L-phenyalanine lower alkyl esters
US5350681A (en) * 1986-08-18 1994-09-27 The Coca-Cola Company Enzymatic membrane method for the synthesis and separation of peptides
US5202235A (en) * 1986-08-18 1993-04-13 The Coca-Cola Company Enzymatic method for the synthesis and separation of peptides
US5336601A (en) * 1986-08-18 1994-08-09 The Coca-Cola Company Enzymatic membrane method for the snythesis and separation of peptides
US4800162A (en) * 1987-04-01 1989-01-24 Sepracor, Inc. Method for resolution of steroisomers in multiphase and extractive membrane reactors
WO1990012883A1 (en) * 1989-04-24 1990-11-01 The Coca-Cola Company Enzymatic membrane method for the synthesis and separation of peptides
US5314807A (en) * 1991-03-29 1994-05-24 Nippon Gohsei Kagaku Kogyo Kabushiki Kaisha Method for producing an angiotensin converting enzyme inhibitor-containing composition
AU650150B2 (en) * 1991-04-12 1994-06-09 Children's Hospital Of Philadelphia, The Novel endopeptidase
US6271023B1 (en) * 1997-02-04 2001-08-07 Akzo Nobel N.V. Module made of at least two-type hollow fibres, and production of same
FR2777803B1 (fr) * 1998-04-24 2000-07-28 Univ Claude Bernard Lyon Procede d'elimination active et selective de petites molecules par pompage enzymatique : dialyse active
US6500571B2 (en) * 1998-08-19 2002-12-31 Powerzyme, Inc. Enzymatic fuel cell
AU2001255521A1 (en) * 2000-04-21 2001-11-07 University Of Rochester Biphasic reaction vessel and methods of use
US6485650B1 (en) * 2000-08-28 2002-11-26 Facilichem, Inc. Liquid membrane separation of enantiomers
US20020114906A1 (en) * 2000-11-20 2002-08-22 Bridgestone Corporation Base body for photosensitive drum and photosensitive drum using the same
CN117820436A (zh) * 2023-03-24 2024-04-05 广东旺合生物科技有限公司 降血糖抗氧化保护肾脏的菊芋肽、制备方法及其在大健康中的应用

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL60227C (de) * 1943-02-23
US3625734A (en) * 1969-10-16 1971-12-07 Usa Ultra-thin liquid membrane construction
US3779907A (en) * 1970-04-13 1973-12-18 Exxon Research Engineering Co Liquid membrane process for the separation of aqueous mixtures
CA947214A (en) * 1971-04-02 1974-05-14 Antoine D'iorio Resolution of racemates of ring-substituted phenylalanines
US3933781A (en) * 1973-11-05 1976-01-20 Monsanto Company Process for the preparation of α-L-aspartyl-L-phenylalanine alkyl esters
US4119493A (en) * 1975-10-23 1978-10-10 (Zaidanhojin) Sagami Chemical Research Center Process for producing a peptide
DE2804892A1 (de) * 1977-02-09 1978-08-10 Procter & Gamble Verfahren zur herstellung von l-threonin und dessen n-acylderivat
US4187086A (en) * 1977-06-15 1980-02-05 General Electric Company Packaged membrane system and replenishment method
US4119408A (en) * 1977-06-22 1978-10-10 General Electric Company Apparatus for maintaining the separation efficiency of immobilized liquid membranes in gas separation
US4251631A (en) * 1978-02-23 1981-02-17 Research Products Rehovot Ltd. Cross-linked enzyme membrane
GB2047564B (en) * 1978-03-27 1983-01-26 Bend Res Inc Separator membrane and process using such membrane for removing ions from an aqueous solution
DE2907450A1 (de) * 1979-02-26 1980-09-04 Rehovot Res Prod Verfahren zur trennung eines waessrigen loesungsgemisches durch elektrodialyse
JPS6339237B2 (de) * 1979-04-06 1988-08-04 Karuruberugu Baiotekunorojii Ltd As
EP0075160B1 (de) * 1981-09-21 1987-01-07 Toyo Soda Manufacturing Co., Ltd. Verfahren zur Gewinnung eines Dipeptidderivates
US4455210A (en) * 1982-03-04 1984-06-19 General Electric Company Multi layer ion exchanging membrane with protected interior hydroxyl ion rejection layer
JPS59183825A (ja) * 1983-04-04 1984-10-19 Nippon Oil & Fats Co Ltd 不均一系反応方法
EP0124313B1 (de) * 1983-04-28 1989-08-02 Ajinomoto Co., Inc. Verfahren zur Herstellung von L-Aspartyl-L-Phenylalanin Methyl-Ester oder von L-Aspartyl-L-Phenylalanin
JPS60164495A (ja) * 1984-01-16 1985-08-27 モンサント　コンパニー Ｎ‐ホルミルアミノ酸とペプチド残基の酵素的結合法
DE3438189A1 (de) * 1984-10-18 1986-04-24 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung aromatisch substituierter l-aminosaeuren
EP0188342B1 (de) * 1985-01-15 1992-05-13 Genentech, Inc. Verfahren und Vorrichtung für enzymatische Synthese
US4743547A (en) * 1985-04-09 1988-05-10 Kuraray Co., Ltd. Method of producing L-phenylalanine

Also Published As

Publication number Publication date
EG18454A (en) 1994-10-30
CN1026498C (zh) 1994-11-09
KR880701778A (ko) 1988-11-05
WO1988001298A2 (en) 1988-02-25
PT85548B (pt) 1990-05-31
GB8903271D0 (en) 1989-08-23
DK209388A (da) 1988-04-15
SG35491G (en) 1991-06-21
WO1988001298A3 (en) 1988-04-07
DE3789309D1 (de) 1994-04-14
FI884359A (fi) 1988-09-22
AU610520B2 (en) 1991-05-23
EP0321479B1 (de) 1994-03-09
GR871290B (en) 1987-12-23
US5002871A (en) 1991-03-26
GB2218991A (en) 1989-11-29
GB2218991B (en) 1991-02-13
NZ231657A (en) 1991-07-26
PT85548A (en) 1987-09-01
DE3789309T2 (de) 1994-10-06
AU7854387A (en) 1988-03-08
IL83564A (en) 1992-03-29
MX168598B (es) 1993-06-01
NZ221467A (en) 1990-07-26
FI884359A0 (fi) 1988-09-22
KR900004070B1 (ko) 1990-06-11
IL83564A0 (en) 1988-01-31
ES2007103A6 (es) 1989-06-01
IL98061A (en) 1992-03-29
AR242264A1 (es) 1993-03-31
PH26764A (en) 1992-09-28
JPH06319592A (ja) 1994-11-22
EP0321479A1 (de) 1989-06-28
DK209388D0 (da) 1988-04-15
CN87106791A (zh) 1988-05-04

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee