ES8801319A1 - Un metodo para la deteccion de anticuerpos especificos de un virus lav en un fluido biologico. - Google Patents
Un metodo para la deteccion de anticuerpos especificos de un virus lav en un fluido biologico.Info
- Publication number
- ES8801319A1 ES8801319A1 ES557358A ES557358A ES8801319A1 ES 8801319 A1 ES8801319 A1 ES 8801319A1 ES 557358 A ES557358 A ES 557358A ES 557358 A ES557358 A ES 557358A ES 8801319 A1 ES8801319 A1 ES 8801319A1
- Authority
- ES
- Spain
- Prior art keywords
- immunogenic compositions
- detection
- gag antigen
- lav
- lav infection
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 101710177291 Gag polyprotein Proteins 0.000 title abstract 2
- 230000002163 immunogen Effects 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 238000001514 detection method Methods 0.000 title 1
- 208000015181 infectious disease Diseases 0.000 title 1
- 241000700605 Viruses Species 0.000 abstract 2
- 239000012634 fragment Substances 0.000 abstract 2
- 108700026244 Open Reading Frames Proteins 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1036—Retroviridae, e.g. leukemia viruses
- C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
- C07K16/1054—Lentiviridae, e.g. HIV, FIV, SIV gag-pol, e.g. p17, p24
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/702—Specific hybridization probes for retroviruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/702—Specific hybridization probes for retroviruses
- C12Q1/703—Viruses associated with AIDS
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
- C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16311—Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
- C12N2740/16322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- AIDS & HIV (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Urology & Nephrology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Communicable Diseases (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Gastroenterology & Hepatology (AREA)
Abstract
METODO PARA DETECTAR ANTICUERPOS ESPECIFICOS DE UN VIRUS LAV EN UN FLUIDO BIOLOGICO. COMPRENDE: A) DEPOSITAR UNO O VARIOS ANTIGENOS PURIFICADOS EN LOS POZOS DE UNA MICROPLACA DE VALORACION; B) INTRODUCIR DILUCIONES CRECIENTES DEL FLUIDO BIOLOGICO EN LOS POZOS; C) INCUBAR LA MICROPLACA; D) LAVAR LA MICROPLACA CON UN TAMPON APROPIADO; E) AÑADIR A LOS POZOS ANTICUERPOS MARCADOS ESPECIFICADOS DIRIGIDOS CONTRA INMUNOGLOBULINAS DE LA SANGRE; F) DETECTAR EL COMPLEJO ANTIGENO-ANTICUERPO FORMADO PARA DETERMINAR PRESENCIA DE ANTICUERPOS LAV EN EL FLUIDO BIOLOGICO. EL ANTIGENO TIENE UN ESQUELETO PEPTIDO QUE CONSTA DE UNA SECUENCIA DE AMINOACIDOS CODIFICADA POR LOS SISTEMAS DE LECTURA ABIERTOS DEL GLUCOMA LAV. SE UTILIZAN COMO ANTIVIRICOS.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8416013A FR2571968B1 (fr) | 1984-10-18 | 1984-10-18 | Virus purifie des lymphadenopathies et du syndrome d'immuno-depression acquise et antigenes d'enveloppe de ce virus, procede d'obtention de ce virus et de ces antigenes d'enveloppe de ce virus, applications de ce virus ou de ces antigenes a la preparation de compositions immunogenes ou pour le diagnostic des susdites affections. |
GB848429099A GB8429099D0 (en) | 1984-11-16 | 1984-11-16 | Closed dna sequences |
GB858501473A GB8501473D0 (en) | 1985-01-21 | 1985-01-21 | Cloned dna sequences |
Publications (2)
Publication Number | Publication Date |
---|---|
ES557358A0 ES557358A0 (es) | 1987-12-16 |
ES8801319A1 true ES8801319A1 (es) | 1987-12-16 |
Family
ID=27251244
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES548048A Expired ES8705522A1 (es) | 1984-10-18 | 1985-10-18 | Un procedimiento para la preparacion de derivados purificados de una glicoproteina. |
ES557357A Expired ES8801318A1 (es) | 1984-10-18 | 1987-01-08 | Un procedimiento para la produccion de un peptido. |
ES557358A Expired ES8801319A1 (es) | 1984-10-18 | 1987-01-08 | Un metodo para la deteccion de anticuerpos especificos de un virus lav en un fluido biologico. |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES548048A Expired ES8705522A1 (es) | 1984-10-18 | 1985-10-18 | Un procedimiento para la preparacion de derivados purificados de una glicoproteina. |
ES557357A Expired ES8801318A1 (es) | 1984-10-18 | 1987-01-08 | Un procedimiento para la produccion de un peptido. |
Country Status (15)
Country | Link |
---|---|
EP (5) | EP1279678B1 (es) |
JP (4) | JP2752329B2 (es) |
KR (1) | KR930000189B1 (es) |
AT (6) | ATE86636T1 (es) |
AU (1) | AU603543B2 (es) |
CA (1) | CA1341620C (es) |
DE (7) | DE3588248T2 (es) |
DK (2) | DK174910B1 (es) |
ES (3) | ES8705522A1 (es) |
GR (1) | GR852522B (es) |
HK (2) | HK1050215B (es) |
IE (1) | IE64006B1 (es) |
NZ (1) | NZ230372A (es) |
PT (1) | PT81338B (es) |
WO (1) | WO1986002383A1 (es) |
Families Citing this family (89)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8423659D0 (en) * | 1984-09-19 | 1984-10-24 | Pasteur Institut | Cloned dna sequences |
US5610035A (en) * | 1983-12-05 | 1997-03-11 | Institut Pasteur Centre National De La Recherche Scientific | Methods for the preparation of hybridomas producing lymphadenopathy-associated virus (LAV) GP110-specific monoclonal antibodies and methods for the purification of GP110 employing said monoclonal antibodies |
US9328391B1 (en) | 1984-08-22 | 2016-05-03 | The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Cloning and expression of HIV-1 DNA |
CA1341482C (en) | 1984-10-31 | 2005-05-10 | Paul A. Luciw | Process for preparing fragments of aids-associated retroviruses |
US7273695B1 (en) * | 1984-10-31 | 2007-09-25 | Novartis Vaccines And Diagnostics, Inc. | HIV immunoassays using synthetic envelope polypeptides |
US7285271B1 (en) | 1984-10-31 | 2007-10-23 | Novartis Vaccines And Diagnostics, Inc. | Antigenic composition comprising an HIV gag or env polypeptide |
US4725669A (en) * | 1984-11-09 | 1988-02-16 | President And Fellows Of Harvard College | Assay for detecting infection by human T-cell lymphotropic virus-III |
US6534285B1 (en) | 1984-12-24 | 2003-03-18 | Genentech, Inc. | Molecularly cloned acquired immunodeficiency syndrome polypeptides and their methods of use |
JP2869063B2 (ja) * | 1985-04-08 | 1999-03-10 | ジエネテイツク システムズ コ−ポレイシヨン | LAVに対する抗体と免疫的に反応性であるgagによりコードされたペプチドの発現及び使用 |
NZ215867A (en) * | 1985-04-19 | 1989-10-27 | Hoffmann La Roche | Aids envelope protein, dna vectors and method of production |
US5773210A (en) * | 1985-04-19 | 1998-06-30 | The United States Of America As Represented By The Department Of Health And Human Services | Acquired immune deficiency syndrome (AIDS) viral envelope protein and method of testing for AIDS |
DE3650175T3 (de) | 1985-04-29 | 2007-09-06 | Bio-Rad Laboratories, Inc., Hercules | Synthetische antigene zum nachweis von aids. |
GR862412B (en) * | 1985-09-25 | 1987-01-23 | Oncogen | Vaccines and immuinoassays for acquired immune deficiency syndrome |
FR2593519B1 (fr) * | 1985-09-25 | 1994-01-07 | Oncogen | Vaccin contre le syndrome immunodeficitaire acquis et intermediaires pour la preparation de ce vaccin |
GB8525615D0 (en) * | 1985-10-17 | 1985-11-20 | Hoffmann La Roche | Polypeptides |
WO1987002775A1 (en) * | 1985-10-24 | 1987-05-07 | Southwest Foundation For Biomedical Research | Synthetic peptides and use for diagnosis and vaccination for aids and arc |
US4839288A (en) * | 1986-01-22 | 1989-06-13 | Institut Pasteur | Retrovirus capable of causing AIDS, antigens obtained from this retrovirus and corresponding antibodies and their application for diagnostic purposes |
US6514691B1 (en) | 1986-01-22 | 2003-02-04 | Institut Pasteur | Peptides of human immunodeficiency virus type 2 (HIV-2), antibodies against peptides of HIV-2, and methods and kits for detecting HIV-2 |
DE239425T1 (de) * | 1986-01-22 | 1988-06-30 | Institut Pasteur, Paris | Zum hervorrufen von aids geeigneter retrovirus vom typ hiv-2, sowie seine antigen- und nukleinsaeure-bestandteile. |
US4772547A (en) * | 1986-02-03 | 1988-09-20 | Hoffmann-La Roche Inc. | HTLV-III envelope peptides |
US4734362A (en) * | 1986-02-03 | 1988-03-29 | Cambridge Bioscience Corporation | Process for purifying recombinant proteins, and products thereof |
US6130314A (en) * | 1986-03-26 | 2000-10-10 | Genetic Systems Corporation | Synthetic antigen for the detection of AIDS-related disease |
US5075211A (en) * | 1986-03-26 | 1991-12-24 | Genetic Systems Corporation | Synthetic antigen for the detection of AIDS-related disease |
US4879212A (en) * | 1986-04-02 | 1989-11-07 | United Biomedical Inc. | Peptide composition and method for the detection of antibodies to HTLV-III |
US4943627A (en) * | 1986-06-12 | 1990-07-24 | Biogen, Inc. | Peptides involved in the pathogenesis of HIV infection |
US5017688A (en) * | 1986-06-12 | 1991-05-21 | Biogen, Inc. | Peptides involved in the pathogenesis of HIV infection |
JPH01501547A (ja) * | 1986-06-12 | 1989-06-01 | バイオジェン ナームローズ ベンノットシャップ | Hiv感染の病因に関するペプチド |
DE3722272A1 (de) * | 1986-07-08 | 1988-01-21 | Bio Rad Laboratories | Differenzierung des krankheitszustandes bei aids-antikoerpertests |
EP0255190A3 (en) * | 1986-08-01 | 1990-08-29 | Repligen Corporation | Recombinant polypeptides and their uses, inclusing assay for aids virus |
NZ221440A (en) * | 1986-08-20 | 1991-11-26 | Genetic Systems Corp | Composition containing monoclonal antibodies/peptides useful in treating and diagnosing hiv infections |
US5166050A (en) * | 1986-08-20 | 1992-11-24 | Bristol-Myers Squibb Company | Monoclonal antibodies and peptides useful in treating and diagnosing HIV infections |
JPS63119428A (ja) * | 1986-09-19 | 1988-05-24 | オンコーゲン | エイズの処置のための養子免疫療法の方法 |
US5976541A (en) * | 1988-01-26 | 1999-11-02 | The United States Of America As Represented By The Department Of Health And Human Services | Potent peptide for stimulation of cytotoxic T lymphocytes specific for the HIV-1 envelope |
EP0273716B1 (en) * | 1986-12-30 | 1993-08-11 | THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce | Synthetic peptides which induce cellular immunity to the aids virus and aids viral proteins |
FR2614025B1 (fr) * | 1987-04-15 | 1990-05-18 | Pasteur Institut | Peptides susceptibles d'etre reconnus par des anticorps induits contre des retrovirus d'immunodeficience humaine (virus hiv) leurs applications au diagnostic des infections dues a certains de ces virus et, le cas echeant, a la vaccination contre le sida |
AU608294B2 (en) * | 1987-01-16 | 1991-03-28 | Institut Pasteur | Peptides having immunological properties 2-hiv-2 |
FR2610632B1 (fr) * | 1987-02-11 | 1990-12-21 | Pasteur Institut | Peptides caracteristiques des retrovirus d'immunodeficience humaine (virus hiv) leurs applications au diagnostic des infections dues a certains de ces virus et, le cas echeant, a la vaccination contre le sida |
DE3855869T2 (de) * | 1987-02-20 | 1997-10-02 | Genentech Inc | Verfahren und Zubereitungen für die Verwendung von HIV-env-Polypeptiden und Antikörpern |
NO881151L (no) * | 1987-03-27 | 1988-09-28 | Syntello Ab | Syntetisk hiv-1-antigen. |
AU1711888A (en) * | 1987-04-24 | 1988-12-02 | Biogen, Inc. | Immunotherapeutic methods and compositions |
ATE122237T1 (de) * | 1987-05-29 | 1995-05-15 | Tanox Biosystems Inc | Hiv-1 neutralisierende monoklonale antikörper. |
US5981278A (en) * | 1987-05-29 | 1999-11-09 | Tanox, Inc. | Chimeric monoclonal antibodies which neutralize HIV-1 infection and their applications in therapy and prevention for AIDS |
US6657050B1 (en) | 1987-05-29 | 2003-12-02 | Tanox, Inc. | Chimeric viral-neutralizing immunoglobulins |
US5834599A (en) * | 1987-05-29 | 1998-11-10 | Tanox Biosystems, Inc. | Immunoconjugates which neutralize HIV-1 infection |
FI872409A0 (fi) * | 1987-05-29 | 1987-05-29 | Labsystems Oy | Foerfarande foer detektering av hiv-1 motkroppar. |
GB8714802D0 (en) * | 1987-06-24 | 1987-07-29 | Proteus Biotech Ltd | Synthetic polypeptides |
NL8702403A (nl) * | 1987-10-09 | 1989-05-01 | Stichting Centr Diergeneeskund | Oligopeptiden en gebruik daarvan voor diagnostische en vaccinatiedoeleinden voor aids en arc. |
ES2080047T3 (es) * | 1987-11-24 | 1996-02-01 | Abbott Lab | Peptidos hiv y metodos para la deteccion de hiv. |
US7442525B1 (en) * | 1987-12-24 | 2008-10-28 | Novartis Vaccines And Diagnostics, Inc. | Method for expressing HIV polypeptides |
SE8705197D0 (sv) * | 1987-12-30 | 1987-12-30 | Jonas Blomberg | New peptides, two diagnostic methods using the peptides and a medicament based on the peptides |
EP0400076B1 (en) * | 1988-01-26 | 1996-05-15 | THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce | A synthetic antigen evoking anti-hiv response |
US5820865A (en) * | 1988-01-26 | 1998-10-13 | The United States Of America As Represented By The Department Of Health And Human Services | Method to induce cytotoxic T Lymphocytes specific for a broad array of HIV-1 isolates using hybrid synthetic peptides |
CA1341285C (en) * | 1988-02-12 | 2001-08-14 | Chang Yi Wang | Synthetic peptides for the detection of antibodies to hiv gp120 envelope protein for diagnosis of aids and pre-aids conditions and as vaccines |
US5763160A (en) * | 1988-02-12 | 1998-06-09 | United Biomedical, Inc. | Synthetic peptides and process of using same for the detection of antibodies to human immunodeficiency virus (HIV) gp120 envelope protein, diagnosis of AIDS and pre-AIDS conditions and as vaccines |
US5562905A (en) * | 1988-04-26 | 1996-10-08 | E. I. Du Pont De Nemours And Company | Human immunodeficiency virus (hiv) env-coded peptide capable of eliciting hiv-inhibiting antibodies in mammals |
EP0339504A3 (en) * | 1988-04-26 | 1990-09-12 | The Du Pont Merck Pharmaceutical Company | Human immunodeficiency virus (hiv) env-coded peptide capable of eliciting hiv-inhibiting antibodies in mammals |
FR2632310B1 (fr) * | 1988-06-06 | 1992-04-10 | Pasteur Institut | Peptides ayant des proprietes protectrices d'un virus pathogene du type hiv dans des cellules sensibles |
EP0657532B1 (en) | 1988-06-09 | 2003-12-17 | N.V. Innogenetics S.A. | HIV-3 retrovirus strains and their use |
ATE134195T1 (de) * | 1988-06-10 | 1996-02-15 | United Biomedical Inc | Peptidfragmente von hiv |
US5185147A (en) * | 1988-08-19 | 1993-02-09 | Cellular Products, Inc. | Short polypeptide sequences useful in the production and detection of antibodies against human immunodeficiency virus |
EP0418347A4 (en) * | 1989-02-28 | 1994-12-14 | Univ New York | Human monoclonal antibodies to human immunodeficiency virus |
US5731189A (en) * | 1989-02-28 | 1998-03-24 | New York University | Human monoclonal antibodies to human immunodeficiency virus |
GB8910145D0 (en) * | 1989-05-03 | 1989-06-21 | Connaught Lab | Synthetic peptides for an hiv-1 vaccine |
US7022814B1 (en) | 1992-01-21 | 2006-04-04 | Institut Pasteur And Institut National De La Sante Et De La Recherche Medicale | Nucleotide sequences derived from the genome of retroviruses of the HIV-1, HIV-2 and SIV type, and their uses in particular for the amplification of the genomes of these retroviruses and for the in vitro diagnosis of the diseases due to these viruses |
FR2647810B1 (fr) * | 1989-06-02 | 1994-07-22 | Pasteur Institut | Amorces oligonucleotidiques pour l'amplification du genome des retrovirus du type hiv-2 et siv, et leurs applications au diagnostic in vitro des infections dues a ces virus |
DE69034220T2 (de) | 1989-06-02 | 2006-12-28 | Institut Pasteur | Nukleotid-Sequenzen von HIV-1, HIV-2 and SIV Retrovirusgenommen, ihre Verwendung zur Amplifizierung von diesen Retrovieren und zur in vitro Diagnostik von diesen Viren verursachten Infektion |
US6165710A (en) * | 1989-10-23 | 2000-12-26 | Robinson; James E. | Method for immobilizing viral glycoproteins for use in solid-phase immunoassays |
US6248574B1 (en) * | 1989-12-13 | 2001-06-19 | Avigdor Shaffermann | Polypeptides selectively reactive with antibodies against human immunodeficiency virus and vaccines comprising the polypeptides |
WO1991009869A1 (en) * | 1990-01-05 | 1991-07-11 | Medical Research Council | Hiv-1 core protein fragments |
SE468168B (sv) * | 1990-02-20 | 1992-11-16 | Replico Medical Ab | Hiv-1, p24 peptider, diagnostiska antigener och foerfarande foer saerskiljande diagnostik av preliminaert hiv-1 positiva serumprov |
ES2053014T5 (es) | 1990-06-15 | 2001-02-16 | Innogenetics Nv | El retrovirus sivcpz-ant y sus usos. |
US5346989A (en) * | 1990-08-22 | 1994-09-13 | Syntello Vaccine Development Kb | Peptides for use in induction of T cell activation against HIV-1 |
ATE238065T1 (de) * | 1990-09-27 | 2003-05-15 | Tripep Ab | Peptide zur verwendung in impfung und anregung von antikörperbildung gegen menschliches immunschwäche virus |
CA2092546A1 (fr) * | 1990-09-27 | 1992-03-28 | Luc Montagnier | Peptides inducteurs d'anticorps inhibant des retrovirus du type hiv et anticorps diriges contre ces peptides |
US5840313A (en) * | 1990-09-27 | 1998-11-24 | Syntello Vaccine Development Kb | Peptides for use in vaccination and induction of neutralizing antibodies against human immunodeficiency virus |
US5871746A (en) * | 1990-12-18 | 1999-02-16 | Institut National De La Sainte Et De La Recherche Medicale (Inserm) | Cytotoxic T lymphocyte-inducing lipopeptides and use as vaccines |
CA2059317A1 (en) * | 1991-01-15 | 1992-07-16 | Yi Zeng | Immuno-enzymatic test for detection of hiv-1 antibody |
WO1992021377A1 (en) * | 1991-06-03 | 1992-12-10 | Syntello Inc. | Peptides for use in induction of t cell activation against hiv-1 |
FR2677364A1 (fr) * | 1991-06-05 | 1992-12-11 | Pasteur Institut | Sequences peptidiques de la glycoproteine externe d'enveloppe du retrovirus hiv-1. |
FR2677654B1 (fr) * | 1991-06-17 | 1995-11-17 | Pasteur Merieux Serums Vacc | Composes a effet immunogene anti-cytokine, a effet immunogene anticytostatique ou a effet vaccinal anti-infection a hiv. |
US6479055B1 (en) | 1993-06-07 | 2002-11-12 | Trimeris, Inc. | Methods for inhibition of membrane fusion-associated events, including respiratory syncytial virus transmission |
DE4405810A1 (de) * | 1994-02-23 | 1995-08-24 | Behringwerke Ag | Von einem Retrovirus aus der HIV-Gruppe abgeleitete Peptide und deren Verwendung |
AU7465696A (en) * | 1995-10-20 | 1997-05-07 | Duke University | Synthetic vaccine for protection against human immunodeficiency virus infection |
FR2756843B1 (fr) | 1996-12-09 | 1999-01-22 | Inst Nat Sante Rech Med | Souches de vih-1 non-m non-o, fragments et applications |
FR2767337B1 (fr) | 1997-08-14 | 2002-07-05 | Pasteur Institut | Sequences nucleiques de polypeptides exportes de mycobacteri es, vecteurs les comprenant et applications au diagnostic et a la prevention de la tuberculose |
EP1307130A4 (en) * | 2000-02-04 | 2005-01-12 | Beth Israel Hospital | VACCINE AGAINST HUMAN IMMUNE WEAK VIRUS |
US20030044771A1 (en) * | 2001-08-30 | 2003-03-06 | Anderson Norman G. | Method for discovering new infectious particles |
DK1350839T3 (da) | 2002-04-05 | 2010-07-12 | Pasteur Institut | Identificering af de virulensassocierede regioner RD1 og RD5, hvilket muliggør udvikling af forbedrede vacciner af M. bovis BCG og M. microti |
DE60336978D1 (de) * | 2003-04-11 | 2011-06-16 | Pasteur Institut | Synthetische Peptid-HIV-Vakzine: das CBD-Epitop als effizientes Immunogen zur Induktion HIV-neutralisierender Antikörper |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS59104325A (ja) * | 1982-12-07 | 1984-06-16 | Japan Found Cancer | ヒト白血病ウイルスの遺伝子rnaに相補性を示すdna |
EP0115459A3 (en) * | 1983-01-26 | 1986-11-20 | University Of Medicine And Dentistry Of New Jersey | Hematological prediction of sepsis and other disease states |
EP0151579B1 (en) * | 1983-04-27 | 1995-09-06 | The President And Fellows Of Harvard College | Method and products for detection of human t cell leukemia virus |
GB8423659D0 (en) * | 1984-09-19 | 1984-10-24 | Pasteur Institut | Cloned dna sequences |
US4520113A (en) * | 1984-04-23 | 1985-05-28 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Serological detection of antibodies to HTLV-III in sera of patients with AIDS and pre-AIDS conditions |
JPS60226658A (ja) * | 1984-04-25 | 1985-11-11 | Matsushita Electric Works Ltd | 加熱器 |
JPS60246102A (ja) * | 1984-05-21 | 1985-12-05 | Matsushita Electric Ind Co Ltd | 分布結合回路 |
IL76082A (en) | 1984-08-22 | 1991-07-18 | Us Health | Molecular clones of the genome of htlv-iii and a process for the preparation thereof |
US9328391B1 (en) | 1984-08-22 | 2016-05-03 | The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Cloning and expression of HIV-1 DNA |
JPS6226300A (ja) * | 1984-10-10 | 1987-02-04 | セントコ−・インコ−ポレ−テツド | Htlv−3dnaのクロ−ニングおよび発現 |
CA1341482C (en) | 1984-10-31 | 2005-05-10 | Paul A. Luciw | Process for preparing fragments of aids-associated retroviruses |
DE3588134T2 (de) | 1984-12-24 | 1997-03-20 | Genentech Inc | Fusionen von AIDS-verwandten Polypeptiden |
-
1985
- 1985-10-18 NZ NZ230372A patent/NZ230372A/en unknown
- 1985-10-18 GR GR852522A patent/GR852522B/el unknown
- 1985-10-18 EP EP02017001A patent/EP1279678B1/en not_active Expired - Lifetime
- 1985-10-18 DE DE3588248T patent/DE3588248T2/de not_active Expired - Lifetime
- 1985-10-18 IE IE258785A patent/IE64006B1/en not_active IP Right Cessation
- 1985-10-18 EP EP90105190A patent/EP0387915B1/en not_active Expired - Lifetime
- 1985-10-18 AT AT90105190T patent/ATE86636T1/de not_active IP Right Cessation
- 1985-10-18 EP EP90105189A patent/EP0387914B1/en not_active Expired - Lifetime
- 1985-10-18 AT AT91113062T patent/ATE250083T1/de not_active IP Right Cessation
- 1985-10-18 KR KR1019860700374A patent/KR930000189B1/ko not_active IP Right Cessation
- 1985-10-18 AU AU50617/85A patent/AU603543B2/en not_active Expired
- 1985-10-18 DE DE3588251T patent/DE3588251T2/de not_active Expired - Lifetime
- 1985-10-18 WO PCT/EP1985/000548 patent/WO1986002383A1/en active IP Right Grant
- 1985-10-18 DE DE90105189T patent/DE3587512T2/de not_active Expired - Lifetime
- 1985-10-18 CA CA493377A patent/CA1341620C/en active Active
- 1985-10-18 EP EP85905513A patent/EP0201540B2/en not_active Expired - Lifetime
- 1985-10-18 PT PT81338A patent/PT81338B/pt unknown
- 1985-10-18 AT AT02008713T patent/ATE286132T1/de not_active IP Right Cessation
- 1985-10-18 AT AT02017001T patent/ATE373010T1/de not_active IP Right Cessation
- 1985-10-18 DE DE9090105190T patent/DE3587181T2/de not_active Expired - Lifetime
- 1985-10-18 ES ES548048A patent/ES8705522A1/es not_active Expired
- 1985-10-18 DE DE8585905513T patent/DE3583293D1/de not_active Expired - Lifetime
- 1985-10-18 DE DE200512000039 patent/DE122005000039I1/de active Pending
- 1985-10-18 DE DE3588254T patent/DE3588254T2/de not_active Expired - Lifetime
- 1985-10-18 EP EP91113062A patent/EP0462627B2/en not_active Expired - Lifetime
- 1985-10-18 AT AT85905513T patent/ATE64601T1/de not_active IP Right Cessation
- 1985-10-18 AT AT90105189T patent/ATE92502T1/de not_active IP Right Cessation
-
1986
- 1986-06-18 DK DK198602849A patent/DK174910B1/da not_active IP Right Cessation
-
1987
- 1987-01-08 ES ES557357A patent/ES8801318A1/es not_active Expired
- 1987-01-08 ES ES557358A patent/ES8801319A1/es not_active Expired
-
1993
- 1993-03-26 DK DK199300355A patent/DK172814B1/da not_active IP Right Cessation
-
1994
- 1994-12-28 JP JP6329052A patent/JP2752329B2/ja not_active Expired - Lifetime
-
1996
- 1996-08-20 JP JP8218964A patent/JP2761376B2/ja not_active Expired - Lifetime
- 1996-08-20 JP JP8218963A patent/JP2971034B2/ja not_active Expired - Lifetime
- 1996-10-31 JP JP8290839A patent/JP2777115B2/ja not_active Expired - Lifetime
-
2003
- 2003-02-06 HK HK03100877.5A patent/HK1050215B/zh not_active IP Right Cessation
- 2003-06-17 HK HK03104359A patent/HK1053662A1/xx unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES8801319A1 (es) | Un metodo para la deteccion de anticuerpos especificos de un virus lav en un fluido biologico. | |
MY103182A (en) | Vaccines against acquired immune deficiency syndrome. | |
ES2016426A6 (es) | Un procedimiento para detectar la presencia de anticuerpos frente a virus del sida en el suero humano. | |
DE69637642D1 (de) | Und kombinierte zusammensetzungen und deren verwendung | |
AU543201B2 (en) | Vaccinal complex containing a specific antigen and vaccine containing it | |
UA42668C2 (uk) | Поліпептид, що має антигенні властивості вірусу гепатиту с (hcv) (варіанти), діагностичний реагент для виявлення антитіл до вірусу гепатиту с (варіанти), набір для виявлення антитіл до вірусу гепатиту с (варіанти), спосіб виявлення антитіл до вірусу гепатиту с (варіанти) | |
HK1080506A1 (en) | Fusion proteins of mycobacterium tuberculosis | |
IT1197431B (it) | Antigene anti-malarico, procedimento per la sua preparazione e vaccino che lo contiene | |
DK208987D0 (da) | Polypeptider og antistoffer, som er karakteristiske for papillomvirus, og deres anvendelse ved diagnostiske metoder og i vacciner | |
DK0909323T3 (da) | Helicobacter pylori-bakterioferritin | |
ATE398137T1 (de) | Porphyromonas gingivalis antigene zur diagnose und behandlung von periodontitis | |
DE59508137D1 (de) | Spezifische bindungssubstanzen für antikörper und deren verwendung für immunoassays oder vakzine | |
OA09653A (en) | Rubella peptides | |
IL117151A0 (en) | Novel antigen | |
IT1213576B (it) | Composizione polipeptidica utile per la preparazione di vaccini antimalaria e di kits diagnostici per la determinazione di anticorpi antimerozoite. | |
SU1739559A1 (ru) | Штамм вируса aphtae epizooticae типа o, используемый для изготовления диагностических сывороток и антигенных препаратов |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20071211 |