GR852522B - - Google Patents

Info

Publication number
GR852522B
GR852522B GR852522A GR850102522A GR852522B GR 852522 B GR852522 B GR 852522B GR 852522 A GR852522 A GR 852522A GR 850102522 A GR850102522 A GR 850102522A GR 852522 B GR852522 B GR 852522B
Authority
GR
Greece
Prior art keywords
contg
new
lav
molecular
lymphadenopathies
Prior art date
Application number
GR852522A
Other languages
English (en)
Inventor
Luc Montagnier
Bernard Krust
Solange Chamaret
Francois Clavel
Jean Claude Chermann
Francoise Barre-Sinoussi
Marc Alizon
Pierre Sonigo
Olivier Danos
Cole Stewart
Simon Wain-Hobson
Original Assignee
Pasteur Institut
Centre Nat Rech Scient
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27251244&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GR852522(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from FR8416013A external-priority patent/FR2571968B1/fr
Priority claimed from GB848429099A external-priority patent/GB8429099D0/en
Priority claimed from GB858501473A external-priority patent/GB8501473D0/en
Application filed by Pasteur Institut, Centre Nat Rech Scient filed Critical Pasteur Institut
Publication of GR852522B publication Critical patent/GR852522B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036—Retroviridae, e.g. leukemia viruses
    • C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
    • C07K16/1054—Lentiviridae, e.g. HIV, FIV, SIV gag-pol, e.g. p17, p24
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/702—Specific hybridization probes for retroviruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/702—Specific hybridization probes for retroviruses
    • C12Q1/703—Viruses associated with AIDS
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16311—Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
    • C12N2740/16322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
GR852522A 1984-10-18 1985-10-18 GR852522B (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR8416013A FR2571968B1 (fr) 1984-10-18 1984-10-18 Virus purifie des lymphadenopathies et du syndrome d'immuno-depression acquise et antigenes d'enveloppe de ce virus, procede d'obtention de ce virus et de ces antigenes d'enveloppe de ce virus, applications de ce virus ou de ces antigenes a la preparation de compositions immunogenes ou pour le diagnostic des susdites affections.
GB848429099A GB8429099D0 (en) 1984-11-16 1984-11-16 Closed dna sequences
GB858501473A GB8501473D0 (en) 1985-01-21 1985-01-21 Cloned dna sequences

Publications (1)

Publication Number Publication Date
GR852522B true GR852522B (el) 1986-02-17

Family

ID=27251244

Family Applications (1)

Application Number Title Priority Date Filing Date
GR852522A GR852522B (el) 1984-10-18 1985-10-18

Country Status (15)

Country Link
EP (5) EP0387915B1 (el)
JP (4) JP2752329B2 (el)
KR (1) KR930000189B1 (el)
AT (6) ATE373010T1 (el)
AU (1) AU603543B2 (el)
CA (1) CA1341620C (el)
DE (7) DE3583293D1 (el)
DK (2) DK174910B1 (el)
ES (3) ES8705522A1 (el)
GR (1) GR852522B (el)
HK (2) HK1050215B (el)
IE (1) IE64006B1 (el)
NZ (1) NZ230372A (el)
PT (1) PT81338B (el)
WO (1) WO1986002383A1 (el)

Families Citing this family (89)

* Cited by examiner, † Cited by third party
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GB8423659D0 (en) * 1984-09-19 1984-10-24 Pasteur Institut Cloned dna sequences
US5610035A (en) * 1983-12-05 1997-03-11 Institut Pasteur Centre National De La Recherche Scientific Methods for the preparation of hybridomas producing lymphadenopathy-associated virus (LAV) GP110-specific monoclonal antibodies and methods for the purification of GP110 employing said monoclonal antibodies
US9328391B1 (en) 1984-08-22 2016-05-03 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Cloning and expression of HIV-1 DNA
CA1341482C (en) 1984-10-31 2005-05-10 Paul A. Luciw Process for preparing fragments of aids-associated retroviruses
US7393949B1 (en) 1987-12-24 2008-07-01 Novartis Vaccines And Diagnostics, Inc. Human immunodeficiency virus (HIV) nucleotide sequences
US7273695B1 (en) 1984-10-31 2007-09-25 Novartis Vaccines And Diagnostics, Inc. HIV immunoassays using synthetic envelope polypeptides
US7285271B1 (en) 1984-10-31 2007-10-23 Novartis Vaccines And Diagnostics, Inc. Antigenic composition comprising an HIV gag or env polypeptide
US4725669A (en) * 1984-11-09 1988-02-16 President And Fellows Of Harvard College Assay for detecting infection by human T-cell lymphotropic virus-III
US6534285B1 (en) 1984-12-24 2003-03-18 Genentech, Inc. Molecularly cloned acquired immunodeficiency syndrome polypeptides and their methods of use
JP2869063B2 (ja) * 1985-04-08 1999-03-10 ジエネテイツク システムズ コ−ポレイシヨン ＬＡＶに対する抗体と免疫的に反応性であるｇａｇによりコードされたペプチドの発現及び使用
US5773210A (en) * 1985-04-19 1998-06-30 The United States Of America As Represented By The Department Of Health And Human Services Acquired immune deficiency syndrome (AIDS) viral envelope protein and method of testing for AIDS
DK171119B1 (da) * 1985-04-19 1996-06-17 Hoffmann La Roche AIDS-viruskappeprotein, ekspressionsvektor bærende viruskappeproteinet, transformanter transformeret med ekspressionsvektoren, fremgangsmåde til fremstilling af viruskappeproteinet, fremgangsmåde til detektion af AIDS-antistoffer, fremgangsmåde til bestemmelse af AIDS-virus, vaccine mod AIDS, antistoffer mod viruskappeproteinet samt anvendelse af dette til fremstilling af en vaccine og til testnin
EP0220273B2 (en) 1985-04-29 2007-01-17 Bio-Rad Laboratories, Inc. Synthetic antigens for the detection of aids-related disease
NZ217645A (en) * 1985-09-25 1991-11-26 Oncogen Recombinant viruses expressing lav/htlv-iii related epitopes and vaccine formulations
FR2593519B1 (fr) * 1985-09-25 1994-01-07 Oncogen Vaccin contre le syndrome immunodeficitaire acquis et intermediaires pour la preparation de ce vaccin
GB8525615D0 (en) * 1985-10-17 1985-11-20 Hoffmann La Roche Polypeptides
EP0245362B1 (en) * 1985-10-24 1994-06-29 Ronald C. Kennedy Synthetic peptides and use for diagnosis and vaccination for aids and arc
EP0239425B1 (fr) * 1986-01-22 1989-11-02 Institut Pasteur Rétrovirus du type HIV-2 susceptible de provoquer le SIDA, et ses constituants antigéniques et nucléiques
US6514691B1 (en) 1986-01-22 2003-02-04 Institut Pasteur Peptides of human immunodeficiency virus type 2 (HIV-2), antibodies against peptides of HIV-2, and methods and kits for detecting HIV-2
US4839288A (en) * 1986-01-22 1989-06-13 Institut Pasteur Retrovirus capable of causing AIDS, antigens obtained from this retrovirus and corresponding antibodies and their application for diagnostic purposes
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DE3722272A1 (de) * 1986-07-08 1988-01-21 Bio Rad Laboratories Differenzierung des krankheitszustandes bei aids-antikoerpertests
EP0525828A3 (en) * 1986-08-01 1993-02-24 Repligen Corporation Recombinant polypeptides and their uses, including assay for aids virus
NZ221440A (en) * 1986-08-20 1991-11-26 Genetic Systems Corp Composition containing monoclonal antibodies/peptides useful in treating and diagnosing hiv infections
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US5976541A (en) * 1988-01-26 1999-11-02 The United States Of America As Represented By The Department Of Health And Human Services Potent peptide for stimulation of cytotoxic T lymphocytes specific for the HIV-1 envelope
EP0273716B1 (en) * 1986-12-30 1993-08-11 THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce Synthetic peptides which induce cellular immunity to the aids virus and aids viral proteins
FR2610632B1 (fr) * 1987-02-11 1990-12-21 Pasteur Institut Peptides caracteristiques des retrovirus d'immunodeficience humaine (virus hiv) leurs applications au diagnostic des infections dues a certains de ces virus et, le cas echeant, a la vaccination contre le sida
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US5820865A (en) * 1988-01-26 1998-10-13 The United States Of America As Represented By The Department Of Health And Human Services Method to induce cytotoxic T Lymphocytes specific for a broad array of HIV-1 isolates using hybrid synthetic peptides
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CA2585164C (fr) 1989-06-02 2010-02-02 Institut Pasteur Sequences nucleotidiques issues du genome des retrovirus du type hiv-1, hiv-2 et siv, et leurs applications notamment pour l'amplification des genomes de ces retrovirus et pour lediagnostic in vitro des infections dues a ces virus
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SE468168B (sv) * 1990-02-20 1992-11-16 Replico Medical Ab Hiv-1, p24 peptider, diagnostiska antigener och foerfarande foer saerskiljande diagnostik av preliminaert hiv-1 positiva serumprov
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US5346989A (en) * 1990-08-22 1994-09-13 Syntello Vaccine Development Kb Peptides for use in induction of T cell activation against HIV-1
US5840313A (en) * 1990-09-27 1998-11-24 Syntello Vaccine Development Kb Peptides for use in vaccination and induction of neutralizing antibodies against human immunodeficiency virus
JPH06501260A (ja) * 1990-09-27 1994-02-10 シンテロ　ヴァクシーン　ディベロップメント　ケービー ヒト免疫不全ウィルスに対する中和抗体の誘発とワクチン接種に用いられるペプチド
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DE60336978D1 (de) 2003-04-11 2011-06-16 Pasteur Institut Synthetische Peptid-HIV-Vakzine: das CBD-Epitop als effizientes Immunogen zur Induktion HIV-neutralisierender Antikörper

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WO1984004327A1 (en) * 1983-04-27 1984-11-08 Harvard College Method and products for detection of human t cell leukemia virus
GB8423659D0 (en) * 1984-09-19 1984-10-24 Pasteur Institut Cloned dna sequences
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AU5061785A (en) 1986-05-02
AU603543B2 (en) 1990-11-22
PT81338B (pt) 1987-11-11
EP0201540B2 (en) 2001-10-31
PT81338A (en) 1985-11-01
NZ230372A (en) 1994-02-25
EP0387915B1 (en) 1993-03-10
DK284986D0 (da) 1986-06-18
ATE86636T1 (de) 1993-03-15
ATE250083T1 (de) 2003-10-15
EP0462627B2 (en) 2011-04-27
ATE373010T1 (de) 2007-09-15
DE3588254T2 (de) 2008-06-26
KR880700076A (ko) 1988-02-15
DE3587512D1 (de) 1993-09-09
DE3587181D1 (de) 1993-04-15
KR930000189B1 (ko) 1993-01-11
DE3588248T2 (de) 2004-07-01
EP0462627B1 (en) 2003-09-17
ATE92502T1 (de) 1993-08-15
JP2752329B2 (ja) 1998-05-18
DK174910B1 (da) 2004-02-16
DK35593D0 (da) 1993-03-26
DE3587181T2 (de) 1993-06-24
EP0201540A1 (en) 1986-11-20
WO1986002383A1 (en) 1986-04-24
EP0387915A1 (en) 1990-09-19
ES8705522A1 (es) 1987-05-01
DE3588251T2 (de) 2006-01-12
ES557358A0 (es) 1987-12-16
EP0201540B1 (en) 1991-06-19
ES8801318A1 (es) 1987-12-16
JP2761376B2 (ja) 1998-06-04
HK1053662A1 (en) 2003-10-31
DE3588254D1 (de) 2007-10-25
EP0387914A1 (en) 1990-09-19
JPH09118689A (ja) 1997-05-06
DE3583293D1 (de) 1991-07-25
ES548048A0 (es) 1987-05-01
JPH07309779A (ja) 1995-11-28
ATE64601T1 (de) 1991-07-15
DE122005000039I1 (de) 2006-02-23
IE852587L (en) 1986-04-18
EP0387914B1 (en) 1993-08-04
IE64006B1 (en) 1995-06-28
EP1279678B1 (en) 2007-09-12
ES557357A0 (es) 1987-12-16
HK1050215B (zh) 2005-05-20
DE3587512T2 (de) 1993-12-02
DE3588248D1 (de) 2003-10-23
JP2971034B2 (ja) 1999-11-02
EP0462627A1 (en) 1991-12-27
HK1050215A1 (en) 2003-06-13
DK172814B1 (da) 1999-07-19
DE3588251D1 (de) 2005-02-03
ES8801319A1 (es) 1987-12-16
JPH09178751A (ja) 1997-07-11
JP2777115B2 (ja) 1998-07-16
ATE286132T1 (de) 2005-01-15
EP1279678A1 (en) 2003-01-29
DK35593A (da) 1993-03-26
JPH09132594A (ja) 1997-05-20
DK284986A (da) 1986-08-14
CA1341620C (en) 2011-08-23

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