ID23219A - Trisiklik tersubstitusi - Google Patents

Trisiklik tersubstitusi

Info

Publication number
ID23219A
ID23219A IDP990342D ID990342D ID23219A ID 23219 A ID23219 A ID 23219A ID P990342 D IDP990342 D ID P990342D ID 990342 D ID990342 D ID 990342D ID 23219 A ID23219 A ID 23219A
Authority
ID
Indonesia
Prior art keywords
trisiclic
substituted
substituted trisiclic
Prior art date
Application number
IDP990342D
Other languages
English (en)
Indonesian (id)
Inventor
Nicholas James Bach
Jolie Anne Bastian
Douglas Wade Beight
Michael Dean Kinnick
Michael John Martinel
Edward David Mihelich
John Michael Morin Jr
Daniel Jon Sall
Jason Scott Sawyer
Edward C R Smith
Tulio Suarez
Quiping Wang
Thomas Michael Wilson
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ID23219A publication Critical patent/ID23219A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/70—[b]- or [c]-condensed containing carbocyclic rings other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IDP990342D 1998-04-17 1999-04-15 Trisiklik tersubstitusi ID23219A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6216598A 1998-04-17 1998-04-17

Publications (1)

Publication Number Publication Date
ID23219A true ID23219A (id) 2000-03-30

Family

ID=22040624

Family Applications (1)

Application Number Title Priority Date Filing Date
IDP990342D ID23219A (id) 1998-04-17 1999-04-15 Trisiklik tersubstitusi

Country Status (27)

Country Link
EP (2) EP0950661B1 (pt)
JP (1) JP4435325B2 (pt)
KR (1) KR19990083234A (pt)
CN (1) CN1235968A (pt)
AR (1) AR018185A1 (pt)
AT (2) ATE259818T1 (pt)
AU (1) AU757454B2 (pt)
BR (1) BR9901275A (pt)
CA (1) CA2269256A1 (pt)
CO (1) CO5080728A1 (pt)
CZ (1) CZ137199A3 (pt)
DE (2) DE69914951T2 (pt)
EA (1) EA003129B1 (pt)
ES (2) ES2210979T3 (pt)
HU (1) HUP9901219A1 (pt)
ID (1) ID23219A (pt)
IL (1) IL129484A0 (pt)
NO (1) NO991823L (pt)
NZ (1) NZ335252A (pt)
PE (1) PE20000472A1 (pt)
PL (1) PL332564A1 (pt)
SG (1) SG106035A1 (pt)
SV (1) SV1999000052A (pt)
TR (1) TR199900842A2 (pt)
TW (1) TW555760B (pt)
YU (1) YU19099A (pt)
ZA (1) ZA992773B (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1011670A4 (en) * 1997-08-28 2004-10-27 Lilly Co Eli PROCESS FOR TREATING NON-RHUMATOID POLYARTHRITIS
WO2001074817A1 (en) * 2000-03-30 2001-10-11 Yamanouchi Pharmaceutical Co., Ltd. Hydrazide derivatives
JP2004503586A (ja) * 2000-07-14 2004-02-05 イーライ・リリー・アンド・カンパニー 敗血症の治療方法
ATE329905T1 (de) * 2000-12-18 2006-07-15 Lilly Co Eli Tetracyclische derivate als spla2 inhibitoren
DE60218155D1 (de) * 2001-03-28 2007-03-29 Lilly Co Eli Substituierte carbazole als inhibitoren von spla2
JP2005527466A (ja) 2001-08-09 2005-09-15 イーライ・リリー・アンド・カンパニー ｓＰＬＡ２インヒビターとしてのシクロヘプトＢインドール誘導体
WO2003014082A1 (en) * 2001-08-09 2003-02-20 Eli Lilly And Company Cyclopenta ` b ! indole derivatives as spla2 inhibitors
US6992100B2 (en) 2001-12-06 2006-01-31 Eli Lilly And Company sPLA2 inhibitors
US7608626B2 (en) 2004-11-01 2009-10-27 Wyeth Substituted indolizines and derivatives as CNS agents
EP2476680B1 (en) 2008-01-11 2014-08-27 Albany Molecular Research, Inc. (1-Azinone)-Substituted Pyridoindoles
WO2011003021A1 (en) 2009-07-01 2011-01-06 Albany Molecular Research, Inc. Azinone-substituted azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine mch-1 antagonists, methods of making, and use thereof
WO2012088124A2 (en) 2010-12-21 2012-06-28 Albany Molecular Research, Inc. Tetrahydro-azacarboline mch-1 antagonists, methods of making, and uses thereof
MY165623A (en) * 2011-04-14 2018-04-18 Idorsia Pharmaceuticals Ltd 7-(heteroaryl-amino)-6,7,8,9-tetrahydropyrido[1,2-a]indol acetic acid derivatives and their use as prostaglandin d2 receptor modulators
EP2825542B1 (en) 2012-03-16 2016-09-14 Vitae Pharmaceuticals, Inc. Liver x receptor modulators
KR102069912B1 (ko) 2012-03-16 2020-01-23 비타이 파마슈티컬즈, 엘엘씨 간 x 수용체 조절제

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3979391A (en) * 1972-11-22 1976-09-07 Sterling Drug Inc. 1,2,3,4-Tetrahydrocarbazoles
PT95692A (pt) * 1989-10-27 1991-09-13 American Home Prod Processo para a preparacao de derivados de acidos indole-,indeno-,piranoindole- e tetra-hidrocarbazole-alcanoicos, ou quais sao uteis como inibidores de pla2 e da lipoxigenase
IL109311A0 (en) * 1993-04-16 1994-07-31 Lilly Co Eli 1H-indole-3-acetamide sPla2 inhibitors
IL109309A (en) * 1993-04-16 2000-06-29 Lilly Co Eli 1-H-indole-3-acetic acid hydrazide SPLA2 inhibitors and pharmaceutical compositions containing them
BR9508298A (pt) * 1994-07-21 1998-11-03 Shionogi & Co Inibidores de indolizina de spla2
BR9612347A (pt) * 1995-12-13 1999-07-13 Lilly Co Eli Naftil acetamidas como inibidores de spla2
CA2269203A1 (en) * 1996-10-30 1998-05-07 Nicholas James Bach Substituted tricyclics
EP1007056A1 (en) * 1997-09-26 2000-06-14 Eli Lilly And Company Method for the treatment of cystic fibrosis
CA2310250A1 (en) * 1997-11-14 1999-05-27 August Masaru Watanabe Treatment for alzheimer's disease

Also Published As

Publication number Publication date
DE69912670D1 (de) 2003-12-18
EP1156050A3 (en) 2001-11-28
EA199900304A3 (ru) 2000-04-24
SV1999000052A (es) 2000-03-14
ZA992773B (en) 2002-07-16
BR9901275A (pt) 2000-05-02
ES2210979T3 (es) 2004-07-01
PL332564A1 (en) 1999-10-25
DE69914951T2 (de) 2004-12-23
HUP9901219A1 (hu) 2000-08-28
AU2381899A (en) 1999-10-28
KR19990083234A (ko) 1999-11-25
EP1156050A2 (en) 2001-11-21
ES2213668T3 (es) 2004-09-01
ATE254128T1 (de) 2003-11-15
HU9901219D0 (en) 1999-06-28
EP0950661B1 (en) 2003-11-12
EA199900304A2 (ru) 1999-10-28
AR018185A1 (es) 2001-10-31
SG106035A1 (en) 2004-09-30
PE20000472A1 (es) 2000-06-02
EP0950661A1 (en) 1999-10-20
NZ335252A (en) 2000-11-24
EP1156050B1 (en) 2004-02-18
DE69912670T2 (de) 2004-08-12
CA2269256A1 (en) 1999-10-17
IL129484A0 (en) 2000-02-29
JPH11322745A (ja) 1999-11-24
NO991823D0 (no) 1999-04-16
CO5080728A1 (es) 2001-09-25
ATE259818T1 (de) 2004-03-15
TR199900842A2 (xx) 2000-09-21
CN1235968A (zh) 1999-11-24
JP4435325B2 (ja) 2010-03-17
TW555760B (en) 2003-10-01
CZ137199A3 (cs) 1999-11-17
AU757454B2 (en) 2003-02-20
DE69914951D1 (de) 2004-03-25
YU19099A (sh) 2001-09-28
NO991823L (no) 1999-10-18
EA003129B1 (ru) 2003-02-27

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