US20030040467A1
(en)
|
1998-06-15 |
2003-02-27 |
Mary Ann Pelleymounter |
Ig/ob fusions and uses thereof.
|
US6936439B2
(en)
|
1995-11-22 |
2005-08-30 |
Amgen Inc. |
OB fusion protein compositions and methods
|
US20030026779A1
(en)
*
|
1999-10-15 |
2003-02-06 |
Liming Yu |
Treatment of tumors and viral infections with a hybrid conjugate of interferon and an immunoglobulin Fc
|
US6114110A
(en)
*
|
1996-01-16 |
2000-09-05 |
University Of Michigan |
Isolation and propagation of a human herpesvirus derived from AIDS-associated Kaposi's sarcoma cells
|
US20050033033A1
(en)
*
|
1998-05-04 |
2005-02-10 |
Heinz Kohler |
Trans-membrane-antibody induced inhibition of apoptosis
|
US7569674B2
(en)
*
|
1998-05-04 |
2009-08-04 |
Innexus Biotechnology International Limited |
Autophilic antibodies
|
US20040185039A1
(en)
*
|
2002-08-30 |
2004-09-23 |
Heinz Kohler |
Therapeutic applications of noncovalent dimerizing antibodies
|
US20030103984A1
(en)
*
|
1998-05-04 |
2003-06-05 |
Heinz Kohler |
Fusion proteins of biologically active peptides and antibodies
|
CA2693296C
(en)
|
1997-12-08 |
2013-09-10 |
Merck Patent Gmbh |
Heterodimeric fusion proteins useful for targeted immune therapy and general immune stimulation
|
CA2315944A1
(en)
*
|
1997-12-24 |
1999-07-08 |
Diatech Pty. Ltd. |
Bifunctional molecules
|
US20030105294A1
(en)
*
|
1998-02-25 |
2003-06-05 |
Stephen Gillies |
Enhancing the circulating half life of antibody-based fusion proteins
|
BR9909583A
(pt)
*
|
1998-04-15 |
2002-01-15 |
Lexigen Pharm Corp |
Aumento da resposta imune mediado por uma proteìna de fusão anticorpo-citocina por co-administração com inibidor de angiogênese
|
US20090208418A1
(en)
*
|
2005-04-29 |
2009-08-20 |
Innexus Biotechnology Internaltional Ltd. |
Superantibody synthesis and use in detection, prevention and treatment of disease
|
ATE327254T1
(de)
*
|
1998-10-16 |
2006-06-15 |
Biogen Idec Inc |
Interferon-beta fusionsproteine und deren verwendungen
|
SI1121382T1
(sl)
*
|
1998-10-16 |
2007-02-28 |
Biogen Idec Inc |
Fuzijski proteini interferona-beta in uporabe
|
IL142282A0
(en)
*
|
1998-10-16 |
2002-03-10 |
Biogen Inc |
Compositions containing polymer conjugates of interferon-beta-1a
|
US6660843B1
(en)
*
|
1998-10-23 |
2003-12-09 |
Amgen Inc. |
Modified peptides as therapeutic agents
|
US6913749B2
(en)
*
|
1998-11-02 |
2005-07-05 |
Resistentia Pharmaceuticals Ab |
Immunogenic polypeptides for inducing anti-self IgE responses
|
AU777963B2
(en)
*
|
1999-05-19 |
2004-11-04 |
Merck Patent Gmbh |
Expression and export of interferon-alpha proteins as Fc fusion proteins
|
ES2286029T3
(es)
|
1999-07-07 |
2007-12-01 |
Zymogenetics Inc |
Receptor de citocina humano.
|
US7754855B1
(en)
|
1999-07-13 |
2010-07-13 |
Bolder Biotechnology, Inc. |
Immunoglobulin fusion proteins
|
US7067110B1
(en)
|
1999-07-21 |
2006-06-27 |
Emd Lexigen Research Center Corp. |
Fc fusion proteins for enhancing the immunogenicity of protein and peptide antigens
|
SK782002A3
(en)
*
|
1999-07-21 |
2003-08-05 |
Lexigen Pharm Corp |
FC fusion proteins for enhancing the immunogenicity of protein and peptide antigens
|
ATE316982T1
(de)
|
1999-08-09 |
2006-02-15 |
Lexigen Pharm Corp |
Mehrere zytokin-antikörper komplexen
|
US20050202538A1
(en)
*
|
1999-11-12 |
2005-09-15 |
Merck Patent Gmbh |
Fc-erythropoietin fusion protein with improved pharmacokinetics
|
WO2001036489A2
(en)
|
1999-11-12 |
2001-05-25 |
Merck Patent Gmbh |
Erythropoietin forms with improved properties
|
EP1250424B1
(de)
*
|
2000-01-24 |
2007-02-28 |
Gendaq, Ltd. |
Nucleinsäure bindende polypeptide gekennzeichnet durch flexible linker verbundene nucleinsäuredomäne
|
ATE336514T1
(de)
*
|
2000-02-11 |
2006-09-15 |
Merck Patent Gmbh |
Steigerung der zirkulierenden halbwertzeit von auf antikörpern basierenden fusionsproteinen
|
EP1294401B1
(de)
*
|
2000-06-29 |
2007-08-01 |
EMD Lexigen Research Center Corp. |
Steigerung von durch antikörper-zytokin-fusionsproteine mediierten immunantworten durch eine kombinierte behandlung mit mitteln zur erhöhung der immunzytokinaufnahme
|
AU2002212107A1
(en)
*
|
2000-11-02 |
2002-05-15 |
Maxygen Aps |
New multimeric interferon beta polypeptides
|
US20020169290A1
(en)
*
|
2000-11-02 |
2002-11-14 |
Claus Bornaes |
New multimeric interferon beta polypeptides
|
CA2430192C
(en)
*
|
2000-12-01 |
2014-06-03 |
Diversa Corporation |
Enzymes having dehalogenase activity and methods of use thereof
|
EP1355919B1
(de)
|
2000-12-12 |
2010-11-24 |
MedImmune, LLC |
Moleküle mit längeren halbwertszeiten, zusammensetzungen und deren verwendung
|
US7141392B2
(en)
*
|
2001-01-09 |
2006-11-28 |
Queen Mary And Westfield College |
Latent fusion protein
|
TWI329129B
(en)
*
|
2001-02-08 |
2010-08-21 |
Wyeth Corp |
Modified and stabilized gdf propeptides and uses thereof
|
FR2821625B1
(fr)
*
|
2001-03-01 |
2003-05-16 |
Genodyssee |
Nouveaux polynucleotides comportant un polymorphisme de type snp fonctionnel dans la sequence nucleotidique du gene ifn-alpha-2 ainsi que de nouveaux polypeptides codes par ces polynucleotides et leurs utilisations therapeutiques
|
AU2002250236A1
(en)
*
|
2001-03-02 |
2002-09-19 |
Medimmune, Inc. |
Cd2 antagonists for treatment of autoimmune or inflammatory disease
|
CA2439636A1
(en)
|
2001-03-02 |
2002-09-12 |
Zymogenetics, Inc. |
Mouse cytokine receptor
|
AU2002248571B2
(en)
*
|
2001-03-07 |
2007-01-18 |
Merck Patent Gmbh |
Expression technology for proteins containing a hybrid isotype antibody moiety
|
CN1191271C
(zh)
*
|
2001-03-21 |
2005-03-02 |
中国科学院上海生物化学研究所 |
干扰素-胸腺肽融合蛋白及其制法
|
WO2002079415A2
(en)
*
|
2001-03-30 |
2002-10-10 |
Lexigen Pharmaceuticals Corp. |
Reducing the immunogenicity of fusion proteins
|
FR2823220B1
(fr)
*
|
2001-04-04 |
2003-12-12 |
Genodyssee |
Nouveaux polynucleotides et polypeptides de l'erythropoietine (epo)
|
JP4309662B2
(ja)
*
|
2001-05-03 |
2009-08-05 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング |
腫瘍特異的組換え抗体およびその使用
|
US20020193569A1
(en)
*
|
2001-06-04 |
2002-12-19 |
Idec Pharmaceuticals Corporation |
Bispecific fusion protein and method of use for enhancing effector cell killing of target cells
|
AU2002315157A1
(en)
*
|
2001-06-14 |
2003-01-02 |
Anadys Pharmaceuticals, Inc. |
Methods of screening for ligands of target molecules
|
US7094757B2
(en)
*
|
2001-06-22 |
2006-08-22 |
Roche Diagnostics Corporation |
Complexes comprising a prion protein and a peptidyl prolyl isomerase chaperone, and method for producing and using them
|
US6962982B2
(en)
*
|
2001-06-22 |
2005-11-08 |
Roche Diagnostics Corporation |
Soluble complexes of target proteins and peptidyl prolyl isomerase chaperones and methods of making and using them
|
EP2267452B8
(de)
*
|
2001-06-22 |
2012-11-14 |
Roche Diagnostics GmbH |
Löslicher Komplex mit einem retroviralen Oberflächenglykoprotein
|
CA2452517A1
(en)
*
|
2001-07-11 |
2003-01-23 |
University Of Miami |
Recombinant vsv for the treatment of tumor cells
|
US20030104604A1
(en)
*
|
2001-08-03 |
2003-06-05 |
Weiping Yang |
Genetically engineered bacterial strains for the display of foreign peptides on filamentous phage
|
CN101200503B
(zh)
*
|
2001-08-10 |
2010-07-07 |
中国人民解放军军事医学科学院生物工程研究所 |
血清白蛋白与干扰素的融合蛋白
|
US6900292B2
(en)
*
|
2001-08-17 |
2005-05-31 |
Lee-Hwei K. Sun |
Fc fusion proteins of human erythropoietin with increased biological activities
|
US7320789B2
(en)
|
2001-09-26 |
2008-01-22 |
Wyeth |
Antibody inhibitors of GDF-8 and uses thereof
|
US6797493B2
(en)
*
|
2001-10-01 |
2004-09-28 |
Lee-Hwei K. Sun |
Fc fusion proteins of human granulocyte colony-stimulating factor with increased biological activities
|
EP2354791A1
(de)
*
|
2001-12-04 |
2011-08-10 |
Merck Patent GmbH |
Immunocytokine mit modulierter Selektivität
|
AU2003217612A1
(en)
*
|
2002-02-21 |
2003-09-09 |
Wyeth |
GASP1: a follistatin domain containing protein
|
PL374966A1
(en)
*
|
2002-02-21 |
2005-11-14 |
Wyeth |
Follistatin domain containing proteins
|
WO2003076567A2
(en)
*
|
2002-03-05 |
2003-09-18 |
Eli Lilly And Company |
Heterologous g-csf fusion proteins
|
US20040063912A1
(en)
*
|
2002-03-15 |
2004-04-01 |
The Brigham And Women's Hospital, Inc. |
Central airway administration for systemic delivery of therapeutics
|
EP1553971A4
(de)
*
|
2002-07-17 |
2006-07-05 |
Biogen Idec Inc |
THERAPIEN GEGEN NIERENVERSAGEN MIT INTERFERON-b
|
WO2004022097A1
(en)
*
|
2002-09-05 |
2004-03-18 |
Medimmune, Inc. |
Methods of preventing or treating cell malignancies by administering cd2 antagonists
|
CA2496213C
(en)
*
|
2002-09-16 |
2013-11-19 |
The Johns Hopkins University |
Metalloprotease activation of myostatin, and methods of modulating myostatin activity
|
RS20050300A
(en)
|
2002-10-16 |
2007-08-03 |
Euro-Celtique S.A., |
Antibodies that bind cell-associated ca 125/0772p and methods of use thereof
|
AR047392A1
(es)
|
2002-10-22 |
2006-01-18 |
Wyeth Corp |
Neutralizacion de anticuerpos contra gdf 8 y su uso para tales fines
|
US20040223966A1
(en)
*
|
2002-10-25 |
2004-11-11 |
Wolfman Neil M. |
ActRIIB fusion polypeptides and uses therefor
|
WO2004055056A1
(en)
*
|
2002-12-17 |
2004-07-01 |
Merck Patent Gmbh |
Humanized antibody (h14.18) of the mouse 14.18 antibody binding to gd2 and its fusion with il-2
|
PL376673A1
(pl)
*
|
2003-02-18 |
2006-01-09 |
Merck Patent Gmbh |
Białka fuzyjne mutein interferonu alfa o ulepszonych właściwościach
|
JP2006523655A
(ja)
*
|
2003-04-17 |
2006-10-19 |
アレス トレーディング ソシエテ アノニム |
重症急性呼吸器症候群(sars)におけるインターフェロンベータ
|
CN1535724B
(zh)
*
|
2003-04-23 |
2012-09-05 |
北京金迪克生物技术研究所 |
重组人干扰素在制备预防严重性急性呼吸道综合征的药物的用途
|
TWI353991B
(en)
*
|
2003-05-06 |
2011-12-11 |
Syntonix Pharmaceuticals Inc |
Immunoglobulin chimeric monomer-dimer hybrids
|
US7348004B2
(en)
*
|
2003-05-06 |
2008-03-25 |
Syntonix Pharmaceuticals, Inc. |
Immunoglobulin chimeric monomer-dimer hybrids
|
US20050037947A1
(en)
*
|
2003-05-06 |
2005-02-17 |
Bitonti Alan J. |
Inhibition of drug binding to serum albumin
|
PL2298347T3
(pl)
|
2003-05-06 |
2016-03-31 |
Bioverativ Therapeutics Inc |
Białka chimeryczne czynnika krzepnięcia do leczenia zaburzenia hemostazy
|
US20070161087A1
(en)
*
|
2003-05-29 |
2007-07-12 |
Wolfgang Glaesner |
Glp-1 fusion proteins
|
KR20060026860A
(ko)
*
|
2003-06-02 |
2006-03-24 |
와이어쓰 |
신경근 장애의 치료를 위한, 코르티코스테로이드와 조합된미오스타틴 (gdf8) 저해제의 용도
|
CN1802386B
(zh)
*
|
2003-06-12 |
2010-12-15 |
伊莱利利公司 |
Glp-1类似物融合蛋白质
|
US20050069521A1
(en)
*
|
2003-08-28 |
2005-03-31 |
Emd Lexigen Research Center Corp. |
Enhancing the circulating half-life of interleukin-2 proteins
|
US8110665B2
(en)
|
2003-11-13 |
2012-02-07 |
Hanmi Holdings Co., Ltd. |
Pharmaceutical composition comprising an immunoglobulin FC region as a carrier
|
EP1682584B1
(de)
|
2003-11-13 |
2013-04-17 |
Hanmi Science Co., Ltd. |
Pharmazeutische zusammensetzung, die eine immunglobulin-fc-region als träger enthält
|
BRPI0418286A
(pt)
|
2003-12-30 |
2007-05-02 |
Merck Patent Gmbh |
proteìnas de fusão de il-7
|
EP1699821B1
(de)
*
|
2003-12-31 |
2012-06-20 |
Merck Patent GmbH |
Fc-ERYTHROPOIETIN-FUSIONSPROTEIN MIT VERBESSERTER PHARMAKOKINETIK
|
JP4987484B2
(ja)
|
2004-01-22 |
2012-07-25 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング |
補体結合が低下した抗癌抗体
|
CA2553040A1
(en)
*
|
2004-02-02 |
2005-08-18 |
Ambrx, Inc. |
Modified human four helical bundle polypeptides and their uses
|
US7670595B2
(en)
*
|
2004-06-28 |
2010-03-02 |
Merck Patent Gmbh |
Fc-interferon-beta fusion proteins
|
CA2575563A1
(en)
*
|
2004-08-12 |
2006-02-23 |
Wyeth |
Combination therapy for diabetes, obesity, and cardiovascular diseases using gdf-8 inhibitors
|
US20090249503A1
(en)
*
|
2004-12-06 |
2009-10-01 |
Bolder Biotechnology, Inc. |
Enzyme conjugates for use as detoxifying agents
|
CA2591297C
(en)
*
|
2004-12-09 |
2015-01-13 |
Stephen D. Gillies |
Il-7 variants with reduced immunogenicity
|
JP2008532931A
(ja)
|
2005-02-08 |
2008-08-21 |
ザイモジェネティクス, インコーポレイテッド |
抗il−20、抗il−22および抗il−22ra抗体ならびに結合パートナー、ならびに炎症における使用法
|
EP1864139A2
(de)
*
|
2005-03-23 |
2007-12-12 |
Wyeth |
Nachweis einer immunreaktion auf gdf-8-modulierende wirkstoffe
|
KR100754667B1
(ko)
|
2005-04-08 |
2007-09-03 |
한미약품 주식회사 |
비펩타이드성 중합체로 개질된 면역글로불린 Fc 단편 및이를 포함하는 약제학적 조성물
|
EP3214095B1
(de)
|
2005-05-12 |
2019-12-11 |
ZymoGenetics, Inc. |
Zusammensetzungen und verfahren zur modulation von immunsystemreaktionen
|
WO2006127757A2
(en)
*
|
2005-05-26 |
2006-11-30 |
Schering Corporation |
Interferon-igg fusion
|
AU2006280587B2
(en)
|
2005-08-16 |
2011-02-24 |
Hanmi Science Co., Ltd. |
A method for the mass production of immunoglobulin Fc region deleted initial methionine residues
|
AU2006286489B2
(en)
|
2005-09-01 |
2012-08-09 |
Ares Trading S.A. |
Treatment of optic neuritis
|
US20070104689A1
(en)
*
|
2005-09-27 |
2007-05-10 |
Merck Patent Gmbh |
Compositions and methods for treating tumors presenting survivin antigens
|
CN101351475B
(zh)
*
|
2005-12-30 |
2013-05-15 |
默克专利有限公司 |
具有提高的稳定性的白细胞介素12p40变体
|
DK1966245T3
(da)
|
2005-12-30 |
2011-07-18 |
Merck Patent Gmbh |
Anti-CD19-Antistoffer med reduceret immunogenicitet
|
US7625564B2
(en)
|
2006-01-27 |
2009-12-01 |
Novagen Holding Corporation |
Recombinant human EPO-Fc fusion proteins with prolonged half-life and enhanced erythropoietic activity in vivo
|
EP2027291A2
(de)
|
2006-04-27 |
2009-02-25 |
Pikamab, Inc. |
Verfahren und zusammensetzungen für antikörpertherapie
|
JP2009537605A
(ja)
|
2006-05-24 |
2009-10-29 |
メルク セローノ ソシエテ アノニム |
多発性硬化症を治療するためのクラドリビン・レジメン
|
BRPI0714334A2
(pt)
*
|
2006-07-18 |
2013-05-14 |
Centocor Inc |
mimeticorpos de glp-1 humano aperfeiÇoados, composiÇÕes, mÉtodos e usos
|
EA021255B1
(ru)
|
2006-08-28 |
2015-05-29 |
Киова Хакко Кирин Ко., Лимитед |
Антагонистические моноклональные антитела человека, специфичные в отношении light человека
|
EP2064335A4
(de)
|
2006-10-16 |
2011-03-30 |
Medimmune Llc |
Moleküle mit reduzierter halbwertzeit, zusammensetzungen und ihre verwendung
|
US20090142362A1
(en)
*
|
2006-11-06 |
2009-06-04 |
Avant Immunotherapeutics, Inc. |
Peptide-based vaccine compositions to endogenous cholesteryl ester transfer protein (CETP)
|
KR100888022B1
(ko)
|
2006-12-21 |
2009-03-09 |
재단법인 목암생명공학연구소 |
면역글로불린 Fc와 인간 아포리포단백질(a)크링글절편의 융합단백질 LK8Fc
|
JP5456658B2
(ja)
|
2007-03-30 |
2014-04-02 |
メディミューン,エルエルシー |
抗体製剤
|
US7625555B2
(en)
|
2007-06-18 |
2009-12-01 |
Novagen Holding Corporation |
Recombinant human interferon-like proteins
|
CA2720628A1
(en)
|
2007-07-26 |
2009-01-29 |
Novagen Holding Corporation |
Fusion proteins having mutated immunoglobulin hinge region
|
CN108129573B
(zh)
|
2007-09-21 |
2021-10-08 |
加利福尼亚大学董事会 |
被导靶的干扰素显示强的细胞凋亡和抗肿瘤活性
|
AU2008308509B2
(en)
|
2007-10-04 |
2014-10-23 |
Zymogenetics, Inc. |
B7 family member zB7H6 and related compositions and methods
|
JO3076B1
(ar)
|
2007-10-17 |
2017-03-15 |
Janssen Alzheimer Immunotherap |
نظم العلاج المناعي المعتمد على حالة apoe
|
WO2009065415A1
(en)
|
2007-11-21 |
2009-05-28 |
Roskilde Universitet |
Polypeptides comprising an ice-binding activity
|
EP2231702A1
(de)
*
|
2007-12-21 |
2010-09-29 |
Ifxa A/s |
Proteasehemmer
|
CN102037007A
(zh)
*
|
2008-01-25 |
2011-04-27 |
奥尔胡斯大学 |
选择性外部位点抑制papp-a对igfbp-4的活性
|
CN101939443B
(zh)
|
2008-02-08 |
2014-01-29 |
Ambrx公司 |
经修饰瘦素多肽和其用途
|
CA2731546C
(en)
|
2008-07-23 |
2013-11-19 |
Hanmi Holdings Co., Ltd. |
A polypeptide complex comprising non-peptidyl polymer having three functional ends
|
AU2009274512A1
(en)
|
2008-07-25 |
2010-01-28 |
The Regents Of The University Of Colorado |
Clip inhibitors and methods of modulating immune function
|
CN102405230A
(zh)
*
|
2009-04-22 |
2012-04-04 |
默克专利有限公司 |
具有修饰的FcRn结合位点的抗体融合蛋白
|
WO2010141329A1
(en)
|
2009-06-01 |
2010-12-09 |
Medimmune, Llc |
Molecules with extended half-lives and uses thereof
|
BR112012003064B8
(pt)
|
2009-08-13 |
2021-05-25 |
Crucell Holland Bv |
anticorpo ou fragmento de ligação de antígeno do mesmo, combinação que os compreende, método de detecção de infecção por rsv, moléculas de ácido nucléico, e método de produção de um anticorpo ou fragmento de ligação de antígeno do mesmo
|
US8840889B2
(en)
|
2009-08-13 |
2014-09-23 |
The Johns Hopkins University |
Methods of modulating immune function
|
WO2011035205A2
(en)
|
2009-09-18 |
2011-03-24 |
Calmune Corporation |
Antibodies against candida, collections thereof and methods of use
|
JP5657698B2
(ja)
|
2010-01-19 |
2015-01-21 |
ハンミ サイエンス カンパニー リミテッドHanmi Scienceco.,Ltd. |
持続型顆粒球コロニー刺激因子結合体の液剤
|
US10745467B2
(en)
|
2010-03-26 |
2020-08-18 |
The Trustees Of Dartmouth College |
VISTA-Ig for treatment of autoimmune, allergic and inflammatory disorders
|
CA3079122A1
(en)
|
2010-03-26 |
2011-09-29 |
Trustees Of Dartmouth College |
Vista regulatory t cell mediator protein, vista binding agents and use thereof
|
US20150231215A1
(en)
|
2012-06-22 |
2015-08-20 |
Randolph J. Noelle |
VISTA Antagonist and Methods of Use
|
AR080993A1
(es)
|
2010-04-02 |
2012-05-30 |
Hanmi Holdings Co Ltd |
Formulacion de accion prolongada de interferon beta donde se usa un fragmento de inmunoglobulina
|
US20110243943A1
(en)
*
|
2010-04-02 |
2011-10-06 |
Athena Discovery, Inc. |
Treatment using relaxin-fusion proteins with extended in vivo half-lives
|
EP2558482B1
(de)
|
2010-04-16 |
2017-09-27 |
Janssen Biotech, Inc. |
Genetisch veränderte cysteinproteasen aus pflanzen und ihre verwendung
|
JP5744196B2
(ja)
|
2010-07-09 |
2015-07-08 |
クルセル ホランド ベー ヴェー |
抗ヒト呼吸器多核体ウイルス(rsv)抗体および使用の方法
|
US20130216513A1
(en)
*
|
2010-07-09 |
2013-08-22 |
Biogen Idec Hemophilia Inc. |
Chimeric Clotting Factors
|
NZ605348A
(en)
|
2010-07-09 |
2015-01-30 |
Biogen Idec Hemophilia Inc |
Factor ix polypeptides and methods of use thereof
|
CN102585013B
(zh)
*
|
2011-01-07 |
2014-04-23 |
中国人民解放军军事医学科学院生物工程研究所 |
一种含有ω干扰素的融合蛋白及制备方法
|
DK2668210T3
(da)
|
2011-01-26 |
2020-08-24 |
Celldex Therapeutics Inc |
Anti-kit antistoffer og anvendelser deraf
|
CN102212139A
(zh)
*
|
2011-03-29 |
2011-10-12 |
中国人民解放军第二军医大学 |
森林脑炎病毒包膜E蛋白与人抗体Fc段融合蛋白及其用途
|
US9243049B2
(en)
*
|
2011-08-09 |
2016-01-26 |
Uab Profarma |
Derivatives of recombinant proteins, homo-multimers of granulocyte colony-stimulating factor and method of preparation thereof
|
DK2764565T3
(da)
|
2011-10-05 |
2023-04-17 |
Oned Mat Inc |
Aktive siliciumnanostrukturmaterialer til lithiumionbatterier og fremgangsmåder, sammensætninger, komponenter og anordninger i forbindelser dermed
|
KR102096224B1
(ko)
|
2011-10-28 |
2020-04-03 |
테바 파마슈티컬즈 오스트레일리아 피티와이 엘티디 |
폴리펩티드 구축물 및 이의 용도
|
MX2014005411A
(es)
|
2011-11-04 |
2015-02-12 |
Novartis Ag |
Construcciones prolongadas de la vida media de la proteina relacionada con lipoproteina de baja densidad 6 (lrp6).
|
KR20150002588A
(ko)
*
|
2012-01-19 |
2015-01-07 |
에스비씨 버락 바이오테크 코., 엘티디. |
인터페론 및 면역글로불린 fc 섹션 융합 단백질
|
TWI492952B
(zh)
*
|
2012-01-20 |
2015-07-21 |
Sbc Virbac Ltd |
動物融合重組型干擾素
|
ES2671631T3
(es)
|
2012-04-23 |
2018-06-07 |
Nrl Pharma, Inc. |
Proteína de fusión de lactoferrina y método para la preparación de la misma
|
CN103044554B
(zh)
*
|
2012-05-14 |
2014-08-27 |
旭华(上海)生物研发中心有限公司 |
重组二聚化人尿胰蛋白酶抑制剂、其制备方法及其应用
|
WO2013177231A1
(en)
|
2012-05-21 |
2013-11-28 |
Massachusetts Institute Of Technology |
Translocation of non-natural chemical entities through anthrax protective antigen pore
|
US9890215B2
(en)
|
2012-06-22 |
2018-02-13 |
King's College London |
Vista modulators for diagnosis and treatment of cancer
|
WO2013192504A1
(en)
*
|
2012-06-22 |
2013-12-27 |
The Trustees Of Dartmouth College |
Novel vista-ig constructs and the use of vista-ig for treatment of autoimmune, allergic and inflammatory disorders
|
US9334332B2
(en)
|
2012-07-25 |
2016-05-10 |
Kolltan Pharmaceuticals, Inc. |
Anti-kit antibodies
|
CN109793893B
(zh)
|
2012-09-07 |
2023-05-26 |
达特茅斯大学理事会 |
用于诊断和治疗癌症的vista调节剂
|
AU2013329311A1
(en)
|
2012-10-09 |
2015-04-30 |
Igenica Biotherapeutics, Inc. |
Anti-C16orf54 antibodies and methods of use thereof
|
US9803021B2
(en)
|
2012-12-07 |
2017-10-31 |
The Regents Of The University Of California |
CD138-targeted interferon demonstrates potent apoptotic and anti-tumor activities
|
EP2941243A4
(de)
|
2013-01-04 |
2016-09-14 |
Massachusetts Inst Technology |
Oberflächenbindung bei der verabreichung eines arzneimittels auf nanopartikelbasis in ein gewebe
|
SG11201505926VA
(en)
|
2013-03-15 |
2015-09-29 |
Biogen Ma Inc |
Factor ix polypeptide formulations
|
DK3677591T5
(da)
|
2013-04-29 |
2024-08-26 |
Teva Pharmaceuticals Australia Pty Ltd |
Anti-CD38 antistoffer og fusioner til svækket interferon alpha-2b
|
US11117975B2
(en)
|
2013-04-29 |
2021-09-14 |
Teva Pharmaceuticals Australia Pty Ltd |
Anti-CD38 antibodies and fusions to attenuated interferon alpha-2B
|
WO2014194100A1
(en)
|
2013-05-29 |
2014-12-04 |
The Regents Of The University Of California |
Anti-cspg4 fusions with interferon for the treatment of malignancy
|
CA2914369C
(en)
|
2013-06-06 |
2023-02-14 |
Igenica Biotherapeutics, Inc. |
Anti-c10orf54 antibodies and uses thereof
|
WO2014202089A2
(en)
|
2013-06-18 |
2014-12-24 |
Roskilde Universitet |
Variants of anti-freeze polypeptides
|
AR096891A1
(es)
|
2013-07-12 |
2016-02-03 |
Hanmi Pharm Ind Co Ltd |
Conjugado de monómero polipéptido biológicamente activo y conjugado de fragmento fc de inmunoglobulina, que muestra aclaramiento mediado por receptor reducido, y el método para la preparación del mismo
|
CN105764526B
(zh)
|
2013-08-26 |
2020-12-15 |
生物技术研发公司 |
编码抗唾液酸化路易斯a抗原的人抗体的核酸
|
US11014987B2
(en)
|
2013-12-24 |
2021-05-25 |
Janssen Pharmaceutics Nv |
Anti-vista antibodies and fragments, uses thereof, and methods of identifying same
|
EP4043493A1
(de)
|
2013-12-24 |
2022-08-17 |
Janssen Pharmaceutica NV |
Anti-vista-antikörper und -fragmente
|
JP6837840B2
(ja)
|
2014-01-24 |
2021-03-10 |
エヌジーエム バイオファーマシューティカルス,インコーポレーテッド |
結合タンパク質及びその使用方法
|
GB201403775D0
(en)
|
2014-03-04 |
2014-04-16 |
Kymab Ltd |
Antibodies, uses & methods
|
US9738702B2
(en)
|
2014-03-14 |
2017-08-22 |
Janssen Biotech, Inc. |
Antibodies with improved half-life in ferrets
|
WO2015161832A1
(zh)
*
|
2014-04-25 |
2015-10-29 |
辅仁药业集团有限公司 |
长效重组人干扰素α2b-Fc融合蛋白
|
UA119352C2
(uk)
|
2014-05-01 |
2019-06-10 |
Тева Фармасьютикалз Острейліа Пті Лтд |
Комбінація леналідоміду або помалідоміду і конструкції анти-cd38 антитіло-атенуйований інтерферон альфа-2b та спосіб лікування суб'єкта, який має cd38-експресуючу пухлину
|
KR102246800B1
(ko)
|
2014-05-13 |
2021-04-30 |
바이오아트라, 인코퍼레이티드 |
조건부 활성 생체 단백질
|
US20170267780A1
(en)
|
2014-05-16 |
2017-09-21 |
Medimmune, Llc |
Molecules with altered neonate fc receptor binding having enhanced therapeutic and diagnostic properties
|
AU2015271685B2
(en)
|
2014-06-04 |
2021-02-18 |
Biontech Research And Development, Inc. |
Human monoclonal antibodies to ganglioside GD2
|
US11123426B2
(en)
|
2014-06-11 |
2021-09-21 |
The Trustees Of Dartmouth College |
Use of vista agonists and antagonists to suppress or enhance humoral immunity
|
EP3189152A4
(de)
|
2014-09-03 |
2018-04-04 |
BioAtla LLC |
Entdeckung und herstellung von bedingt aktiven biologischen proteinen in denselben wirten zur herstellung eukaryontischer zellen
|
EA037749B1
(ru)
|
2014-10-29 |
2021-05-18 |
Тева Фармасьютикалз Острэйлиа Пти Лтд |
ВАРИАНТЫ ИНТЕРФЕРОНА 2b
|
CN104403004B
(zh)
|
2014-11-24 |
2017-10-13 |
苏州丁孚靶点生物技术有限公司 |
抗体‑干扰素异二聚体的制备和用途
|
WO2016090347A1
(en)
|
2014-12-05 |
2016-06-09 |
Immunext, Inc. |
Identification of vsig8 as the putative vista receptor and its use thereof to produce vista/vsig8 modulators
|
SG11201704752WA
(en)
|
2014-12-11 |
2017-07-28 |
Pierre Fabre Médicament |
Anti-c10orf54 antibodies and uses thereof
|
PT3265123T
(pt)
|
2015-03-03 |
2023-02-01 |
Kymab Ltd |
Anticorpos, usos e métodos
|
JP7019423B2
(ja)
|
2015-05-06 |
2022-02-15 |
ヤンセン バイオテツク,インコーポレーテツド |
前立腺特異的膜抗原(psma)二重特異性結合剤及びその使用
|
MX2017016647A
(es)
|
2015-06-24 |
2019-04-25 |
Janssen Pharmaceutica Nv |
Anticuerpos y fragmentos anti-vista.
|
WO2017035508A1
(en)
|
2015-08-27 |
2017-03-02 |
Collier R John |
Compositions and methods for treatment of pain
|
TW201718629A
(zh)
*
|
2015-09-25 |
2017-06-01 |
韓美藥品股份有限公司 |
包含多個生理多肽及免疫球蛋白Fc區之蛋白質接合物
|
WO2017058859A1
(en)
|
2015-09-29 |
2017-04-06 |
Celgene Corporation |
Pd-1 binding proteins and methods of use thereof
|
WO2017078839A1
(en)
|
2015-11-02 |
2017-05-11 |
Bioatla, Llc |
Conditionally active polypeptides
|
MX2018009800A
(es)
|
2016-02-12 |
2018-11-09 |
Janssen Pharmaceutica Nv |
Anticuerpos y fragmentos anti-vista, usos de los mismos y procedimientos de identificacion de los mismos.
|
CA3020848A1
(en)
|
2016-04-15 |
2017-10-19 |
Janssen Pharmaceuticals, Inc. |
Anti-human vista antibodies and use thereof
|
JP2019534859A
(ja)
|
2016-09-19 |
2019-12-05 |
セルジーン コーポレイション |
Pd−1結合タンパク質を使用して白斑を治療する方法
|
US10751414B2
(en)
|
2016-09-19 |
2020-08-25 |
Celgene Corporation |
Methods of treating psoriasis using PD-1 binding antibodies
|
CA3080406A1
(en)
|
2016-10-28 |
2018-05-03 |
Nrl Pharma, Inc. |
Lactoferrin/albumin fusion protein and production method thereof
|
EP3534947A1
(de)
|
2016-11-03 |
2019-09-11 |
Kymab Limited |
Antikörper, kombinationen mit antikörpern, biomarker, verwendungen und verfahren
|
WO2019073069A1
(en)
|
2017-10-13 |
2019-04-18 |
Boehringer Ingelheim International Gmbh |
HUMAN ANTIBODIES AGAINST THOMSEN-NEW ANTIGEN (TN)
|
CN112740043A
(zh)
|
2018-07-20 |
2021-04-30 |
皮埃尔法布雷医药公司 |
Vista受体
|
US20210023236A1
(en)
*
|
2019-07-26 |
2021-01-28 |
Massachusetts Institute Of Technology |
Multi-targeted, tunable, sustained delivery of payloads to charged avascular tissues
|
WO2022147463A2
(en)
|
2020-12-31 |
2022-07-07 |
Alamar Biosciences, Inc. |
Binder molecules with high affinity and/ or specificity and methods of making and use thereof
|
EP4047016A1
(de)
|
2021-02-19 |
2022-08-24 |
Université de Strasbourg |
Anti-tenascin-c(tnc)-antikörper (nanobodies) mit einer einzigen domäne und deren verwendung
|
AR128222A1
(es)
|
2022-01-07 |
2024-04-10 |
Johnson & Johnson Entpr Innovation Inc |
MATERIALES Y MÉTODOS DE PROTEÍNAS DE UNIÓN A IL-1b
|
WO2024013727A1
(en)
|
2022-07-15 |
2024-01-18 |
Janssen Biotech, Inc. |
Material and methods for improved bioengineered pairing of antigen-binding variable regions
|
WO2024130158A1
(en)
|
2022-12-16 |
2024-06-20 |
Modernatx, Inc. |
Lipid nanoparticles and polynucleotides encoding extended serum half-life interleukin-22 for the treatment of metabolic disease
|