AR128222A1 - MATERIALES Y MÉTODOS DE PROTEÍNAS DE UNIÓN A IL-1b - Google Patents

MATERIALES Y MÉTODOS DE PROTEÍNAS DE UNIÓN A IL-1b

Info

Publication number
AR128222A1
AR128222A1 ARP230100041A ARP230100041A AR128222A1 AR 128222 A1 AR128222 A1 AR 128222A1 AR P230100041 A ARP230100041 A AR P230100041A AR P230100041 A ARP230100041 A AR P230100041A AR 128222 A1 AR128222 A1 AR 128222A1
Authority
AR
Argentina
Prior art keywords
methods
binding protein
protein materials
antibodies
cells
Prior art date
Application number
ARP230100041A
Other languages
English (en)
Inventor
Gabriel Pascual
Sagit Hindi
Suresh Kumar Swaminathan
Christopher Scott Stevenson
Matthew J Edwards
Original Assignee
Johnson & Johnson Entpr Innovation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johnson & Johnson Entpr Innovation Inc filed Critical Johnson & Johnson Entpr Innovation Inc
Publication of AR128222A1 publication Critical patent/AR128222A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/245—IL-1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

En la presente descripción, en ciertos aspectos, se proporcionan anticuerpos que se unen a IL-1b y composiciones que comprenden los anticuerpos. También se proporcionan métodos para hacer y usar los anticuerpos. Reivindicación 36: Un método para inhibir el crecimiento o proliferación de células que expresan IL-1b, que comprende poner en contacto las células con el anticuerpo de una cualquiera de las reivindicaciones 1 a 24. Reivindicación 42: El método de la reivindicación 40, en donde la enfermedad o trastorno asociado a IL-1b es cáncer.
ARP230100041A 2022-01-07 2023-01-06 MATERIALES Y MÉTODOS DE PROTEÍNAS DE UNIÓN A IL-1b AR128222A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US202263297436P 2022-01-07 2022-01-07

Publications (1)

Publication Number Publication Date
AR128222A1 true AR128222A1 (es) 2024-04-10

Family

ID=84981504

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP230100041A AR128222A1 (es) 2022-01-07 2023-01-06 MATERIALES Y MÉTODOS DE PROTEÍNAS DE UNIÓN A IL-1b

Country Status (4)

Country Link
US (1) US20230227545A1 (es)
AR (1) AR128222A1 (es)
TW (1) TW202337904A (es)
WO (1) WO2023131901A1 (es)

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WO2023131901A1 (en) 2023-07-13
US20230227545A1 (en) 2023-07-20
TW202337904A (zh) 2023-10-01

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