ATE514716T1 - Fragmente toxin-bezogener antikörper, mit antimikrobieller und antiviraler aktivität - Google Patents

Fragmente toxin-bezogener antikörper, mit antimikrobieller und antiviraler aktivität

Info

Publication number
ATE514716T1
ATE514716T1 AT03727860T AT03727860T ATE514716T1 AT E514716 T1 ATE514716 T1 AT E514716T1 AT 03727860 T AT03727860 T AT 03727860T AT 03727860 T AT03727860 T AT 03727860T AT E514716 T1 ATE514716 T1 AT E514716T1
Authority
AT
Austria
Prior art keywords
fragments
antiviral activity
toxin
antimicrobial
microbicidal
Prior art date
Application number
AT03727860T
Other languages
English (en)
Inventor
Luciano Polonelli
Antonio Cassone
Paolo Neri
Luisa Bracci
Luisa Lozzi
Original Assignee
Univ Siena
Luciano Polonelli
Ist Superiore Sanita
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Siena, Luciano Polonelli, Ist Superiore Sanita filed Critical Univ Siena
Application granted granted Critical
Publication of ATE514716T1 publication Critical patent/ATE514716T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT03727860T 2002-05-10 2003-05-09 Fragmente toxin-bezogener antikörper, mit antimikrobieller und antiviraler aktivität ATE514716T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0210783.7A GB0210783D0 (en) 2002-05-10 2002-05-10 Anti-microbial polypeptides
PCT/IB2003/002348 WO2003095493A2 (en) 2002-05-10 2003-05-09 Toxin-related antibodies with antimicrobial and antiviral activity

Publications (1)

Publication Number Publication Date
ATE514716T1 true ATE514716T1 (de) 2011-07-15

Family

ID=9936462

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03727860T ATE514716T1 (de) 2002-05-10 2003-05-09 Fragmente toxin-bezogener antikörper, mit antimikrobieller und antiviraler aktivität

Country Status (12)

Country Link
US (1) US7722876B2 (de)
EP (1) EP1504036B1 (de)
JP (1) JP4405912B2 (de)
AT (1) ATE514716T1 (de)
AU (1) AU2003233108A1 (de)
BR (1) BR0309921A (de)
CA (1) CA2484704A1 (de)
CO (1) CO7220324A2 (de)
DK (1) DK1504036T3 (de)
GB (1) GB0210783D0 (de)
NZ (1) NZ536957A (de)
WO (1) WO2003095493A2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2006093071A1 (ja) * 2005-02-28 2008-08-07 株式会社ジーンケア研究所 βグルカン合成酵素を有する真菌に対して抗真菌活性を有する抗イディオタイプ抗体、およびその利用
AU2009319864A1 (en) * 2008-11-25 2011-07-14 Biogen Idec Ma Inc. Use of DR6 and P75 antagonists to promote survival of cells of the nervous system
WO2011060393A1 (en) * 2009-11-16 2011-05-19 Rasna Therapeutics Antimicrobial, antiviral, anticancer and immunomodulatory peptides and uses therefore
CA2858350A1 (en) 2011-01-14 2013-07-19 The Regents Of The University Of California Therapeutic antibodies against ror-1 protein and methods for use of same
EP2731677B1 (de) * 2011-07-11 2018-04-18 Glenmark Pharmaceuticals S.A. An ox40 bindende antikörper und ihre verwendungen
WO2020257625A1 (en) * 2019-06-21 2020-12-24 Rowley Paul A Compositions and methods for inhibiting yeast infections
US20220111018A1 (en) * 2020-06-19 2022-04-14 University Of Idaho Compositions and methods for inhibiting yeast infections
CN111848740B (zh) * 2020-08-04 2023-03-24 南京市妇幼保健院 一种阴道分泌源性多肽及其在抑制白色念珠菌感染中的应用
EP4147716A1 (de) * 2021-09-10 2023-03-15 Samatva Research Corporation In einer matrix immobilisierte anti-virus komponente

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
AU669379B2 (en) * 1992-09-07 1996-06-06 Kyowa Hakko Kirin Co., Ltd. Humanized antibodies
WO1998008090A1 (en) 1995-06-06 1998-02-26 Epigen, Inc. Anti-idiotypic antibodies to an epiglycanin
JP3946256B2 (ja) * 1995-09-11 2007-07-18 協和醗酵工業株式会社 ヒトインターロイキン5受容体α鎖に対する抗体
HUP9901562A3 (en) * 1996-05-04 2000-06-28 Astrazeneca Ab Monoclonal antibody to cea, conjugates comprising said antibody, and their therapeutic use in an adept system
ES2364266T3 (es) * 1998-04-03 2011-08-30 Chugai Seiyaku Kabushiki Kaisha Anticuerpo humanizado hacia el factor tisular humano (tf) y procedimiento para construir el anticuerpo humanizado.
ES2270638T3 (es) 1998-10-29 2007-04-01 Dakocytomation Denmark A/S Deteccion de microorganismos acido-resistentes en las heces.
CN1360596A (zh) 1999-02-12 2002-07-24 遗传研究所有限公司 与b7分子发生反应的人源化免疫球蛋白及应用该免疫球蛋白的治疗方法
DE60040466D1 (de) 1999-06-17 2008-11-20 Kyowa Hakko Kogyo Kk Diagnostikum und heilmittel für krankheiten unter teilnahme von makrozyten/makrophagen
US7740841B1 (en) * 2000-01-28 2010-06-22 Sunnybrook Health Science Center Therapeutic method for reducing angiogenesis
EP1130032A1 (de) 2000-02-28 2001-09-05 Gesellschaft für biotechnologische Forschung mbH (GBF) Einzelkette-Antikörper die den menschlichen vaskulären endothelialen Wachstumsfaktorrezeptor-2 (VEGFR-2/KDR) erkennen
DE10019967A1 (de) 2000-04-20 2001-10-25 Fenning Biomed Gmbh Dr Antikörper gegen natives gp96, deren Herstellung und Verwendung
BR0112272A (pt) * 2000-06-22 2003-05-06 Genentech Inc Anticorpo monoclonal anti-trkc agonista, cadeia pesada de anticorpo anti-trkc, cadeia leve de anticorpo anti-trkc, cadeia pesada de anticorpo anti-trkc murino, cadeia pesada de anticorpo anti-trkc humano, anticorpo agonista anti-trkc murino, anticorpo agonista anti-trkc humano, moléculas de ácido nucléico isolado, moléculas de ácido nucléico, vetor, linhagens de células hospedeiras, linhagens de células de hibridoma, célula hospedeira, polipeptìdeo, composição farmacêutica, método para o tratamento de neuropatia ou doença neurodegenerativa ou reparo de uma célula nervosa lesionada, método para aumentar a proliferação, manutenção ou regeneração de neurÈnios periféricos, método para o tratamento de doença ou condição que envolve a degeneração celular em um paciente mamìfero, método de indução de angiogênese, método de fabricação de um anticorpo anti-trkc, usos de um anticorpo

Also Published As

Publication number Publication date
JP4405912B2 (ja) 2010-01-27
EP1504036A2 (de) 2005-02-09
JP2006506959A (ja) 2006-03-02
CA2484704A1 (en) 2003-11-20
DK1504036T3 (da) 2011-10-24
WO2003095493A2 (en) 2003-11-20
US7722876B2 (en) 2010-05-25
CO7220324A2 (es) 2015-03-20
EP1504036B1 (de) 2011-06-29
GB0210783D0 (en) 2002-06-19
AU2003233108A1 (en) 2003-11-11
NZ536957A (en) 2006-07-28
US20060280750A1 (en) 2006-12-14
WO2003095493A3 (en) 2004-06-03
BR0309921A (pt) 2005-02-09

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