ATE514716T1 - Fragmente toxin-bezogener antikörper, mit antimikrobieller und antiviraler aktivität - Google Patents

Fragmente toxin-bezogener antikörper, mit antimikrobieller und antiviraler aktivität

Info

Publication number
ATE514716T1
ATE514716T1 AT03727860T AT03727860T ATE514716T1 AT E514716 T1 ATE514716 T1 AT E514716T1 AT 03727860 T AT03727860 T AT 03727860T AT 03727860 T AT03727860 T AT 03727860T AT E514716 T1 ATE514716 T1 AT E514716T1
Authority
AT
Austria
Prior art keywords
fragments
antiviral activity
toxin
antimicrobial
microbicidal
Prior art date
Application number
AT03727860T
Other languages
English (en)
Inventor
Luciano Polonelli
Antonio Cassone
Paolo Neri
Luisa Bracci
Luisa Lozzi
Original Assignee
Univ Siena
Luciano Polonelli
Ist Superiore Sanita
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Siena, Luciano Polonelli, Ist Superiore Sanita filed Critical Univ Siena
Application granted granted Critical
Publication of ATE514716T1 publication Critical patent/ATE514716T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
AT03727860T 2002-05-10 2003-05-09 Fragmente toxin-bezogener antikörper, mit antimikrobieller und antiviraler aktivität ATE514716T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0210783.7A GB0210783D0 (en) 2002-05-10 2002-05-10 Anti-microbial polypeptides
PCT/IB2003/002348 WO2003095493A2 (en) 2002-05-10 2003-05-09 Toxin-related antibodies with antimicrobial and antiviral activity

Publications (1)

Publication Number Publication Date
ATE514716T1 true ATE514716T1 (de) 2011-07-15

Family

ID=9936462

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03727860T ATE514716T1 (de) 2002-05-10 2003-05-09 Fragmente toxin-bezogener antikörper, mit antimikrobieller und antiviraler aktivität

Country Status (12)

Country Link
US (1) US7722876B2 (de)
EP (1) EP1504036B1 (de)
JP (1) JP4405912B2 (de)
AT (1) ATE514716T1 (de)
AU (1) AU2003233108A1 (de)
BR (1) BR0309921A (de)
CA (1) CA2484704A1 (de)
CO (1) CO7220324A2 (de)
DK (1) DK1504036T3 (de)
GB (1) GB0210783D0 (de)
NZ (1) NZ536957A (de)
WO (1) WO2003095493A2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006093071A1 (ja) * 2005-02-28 2006-09-08 Genecare Research Institute Co., Ltd. βグルカン合成酵素を有する真菌に対して抗真菌活性を有する抗イディオタイプ抗体、およびその利用
MX2011005481A (es) 2008-11-25 2011-08-17 Biogen Idec Inc Uso de antagonistas de receptor de muerte 6 (drg6) y de p75 para promover la supervivencia de células del sistema nervioso.
WO2011060393A1 (en) * 2009-11-16 2011-05-19 Rasna Therapeutics Antimicrobial, antiviral, anticancer and immunomodulatory peptides and uses therefore
EP3252076B1 (de) 2011-01-14 2019-09-04 The Regents Of The University Of California Diagnostische verwendung von antikörpern gegen das protein ror-1
EP2731677B1 (de) 2011-07-11 2018-04-18 Glenmark Pharmaceuticals S.A. An ox40 bindende antikörper und ihre verwendungen
WO2020257625A1 (en) * 2019-06-21 2020-12-24 Rowley Paul A Compositions and methods for inhibiting yeast infections
US20220111018A1 (en) * 2020-06-19 2022-04-14 University Of Idaho Compositions and methods for inhibiting yeast infections
CN111848740B (zh) * 2020-08-04 2023-03-24 南京市妇幼保健院 一种阴道分泌源性多肽及其在抑制白色念珠菌感染中的应用
EP4147716A1 (de) * 2021-09-10 2023-03-15 Samatva Research Corporation In einer matrix immobilisierte anti-virus komponente

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5530101A (en) * 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
AU669379B2 (en) * 1992-09-07 1996-06-06 Kyowa Hakko Kirin Co., Ltd. Humanized antibodies
WO1998008090A1 (en) * 1995-06-06 1998-02-26 Epigen, Inc. Anti-idiotypic antibodies to an epiglycanin
WO1997010354A1 (fr) * 1995-09-11 1997-03-20 Kyowa Hakko Kogyo Co., Ltd. Anticorps de la chaine alpha du recepteur de l'interleukine 5 humaine
SK150298A3 (en) * 1996-05-04 1999-04-13 Zeneca Ltd Monoclonal antibody to cea, conjugates comprising said antibody, and their therapeutic use in an adept system
AU752730B2 (en) * 1998-04-03 2002-09-26 Chugai Seiyaku Kabushiki Kaisha Humanized antibody against human tissue factor (TF) and process for constructing humanized antibody
ES2270638T3 (es) * 1998-10-29 2007-04-01 Dakocytomation Denmark A/S Deteccion de microorganismos acido-resistentes en las heces.
WO2000047625A2 (en) * 1999-02-12 2000-08-17 Genetics Institute, Inc. Humanized immunoglobulin reactive with b7 molecules and methods of treatment therewith
DE60040466D1 (de) * 1999-06-17 2008-11-20 Kyowa Hakko Kogyo Kk Diagnostikum und heilmittel für krankheiten unter teilnahme von makrozyten/makrophagen
US7740841B1 (en) 2000-01-28 2010-06-22 Sunnybrook Health Science Center Therapeutic method for reducing angiogenesis
EP1130032A1 (de) 2000-02-28 2001-09-05 Gesellschaft für biotechnologische Forschung mbH (GBF) Einzelkette-Antikörper die den menschlichen vaskulären endothelialen Wachstumsfaktorrezeptor-2 (VEGFR-2/KDR) erkennen
DE10019967A1 (de) * 2000-04-20 2001-10-25 Fenning Biomed Gmbh Dr Antikörper gegen natives gp96, deren Herstellung und Verwendung
KR100823764B1 (ko) * 2000-06-22 2008-04-21 제넨테크, 인크. 아고니스트 안티-티알케이-씨 모노클로날 항체

Also Published As

Publication number Publication date
CA2484704A1 (en) 2003-11-20
WO2003095493A3 (en) 2004-06-03
BR0309921A (pt) 2005-02-09
AU2003233108A1 (en) 2003-11-11
GB0210783D0 (en) 2002-06-19
JP4405912B2 (ja) 2010-01-27
US20060280750A1 (en) 2006-12-14
US7722876B2 (en) 2010-05-25
DK1504036T3 (da) 2011-10-24
CO7220324A2 (es) 2015-03-20
EP1504036B1 (de) 2011-06-29
WO2003095493A2 (en) 2003-11-20
EP1504036A2 (de) 2005-02-09
JP2006506959A (ja) 2006-03-02
NZ536957A (en) 2006-07-28

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