DK1504036T3 - Toxinrelaterede fragmenter af antistoffer med antimikrobiel og antiviral aktivitet - Google Patents

Toxinrelaterede fragmenter af antistoffer med antimikrobiel og antiviral aktivitet

Info

Publication number
DK1504036T3
DK1504036T3 DK03727860.3T DK03727860T DK1504036T3 DK 1504036 T3 DK1504036 T3 DK 1504036T3 DK 03727860 T DK03727860 T DK 03727860T DK 1504036 T3 DK1504036 T3 DK 1504036T3
Authority
DK
Denmark
Prior art keywords
antibodies
antiviral activity
toxin
antimicrobial
microbicidal
Prior art date
Application number
DK03727860.3T
Other languages
English (en)
Inventor
Luciano Polonelli
Antonio Cassone
Paolo Neri
Luisa Bracci
Luisa Lozzi
Original Assignee
Ist Superiore Sanita
Univ Siena
Luciano Polonelli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ist Superiore Sanita, Univ Siena, Luciano Polonelli filed Critical Ist Superiore Sanita
Application granted granted Critical
Publication of DK1504036T3 publication Critical patent/DK1504036T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK03727860.3T 2002-05-10 2003-05-09 Toxinrelaterede fragmenter af antistoffer med antimikrobiel og antiviral aktivitet DK1504036T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0210783.7A GB0210783D0 (en) 2002-05-10 2002-05-10 Anti-microbial polypeptides
PCT/IB2003/002348 WO2003095493A2 (en) 2002-05-10 2003-05-09 Toxin-related antibodies with antimicrobial and antiviral activity

Publications (1)

Publication Number Publication Date
DK1504036T3 true DK1504036T3 (da) 2011-10-24

Family

ID=9936462

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03727860.3T DK1504036T3 (da) 2002-05-10 2003-05-09 Toxinrelaterede fragmenter af antistoffer med antimikrobiel og antiviral aktivitet

Country Status (12)

Country Link
US (1) US7722876B2 (da)
EP (1) EP1504036B1 (da)
JP (1) JP4405912B2 (da)
AT (1) ATE514716T1 (da)
AU (1) AU2003233108A1 (da)
BR (1) BR0309921A (da)
CA (1) CA2484704A1 (da)
CO (1) CO7220324A2 (da)
DK (1) DK1504036T3 (da)
GB (1) GB0210783D0 (da)
NZ (1) NZ536957A (da)
WO (1) WO2003095493A2 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2006093071A1 (ja) * 2005-02-28 2008-08-07 株式会社ジーンケア研究所 βグルカン合成酵素を有する真菌に対して抗真菌活性を有する抗イディオタイプ抗体、およびその利用
CA2744043A1 (en) 2008-11-25 2010-06-03 Biogen Idec Ma Inc. Use of dr6 and p75 antagonists to promote survival of cells of the nervous system
WO2011060393A1 (en) * 2009-11-16 2011-05-19 Rasna Therapeutics Antimicrobial, antiviral, anticancer and immunomodulatory peptides and uses therefore
PT2663579T (pt) 2011-01-14 2017-07-28 Univ California Terapêutica de anticorpos contra a proteína r0r-1 e métodos para sua utilização
EA036047B1 (ru) 2011-07-11 2020-09-18 Икнос Сайенсиз Са Антитела, которые связываются с ox40, и их применение
WO2020257625A1 (en) * 2019-06-21 2020-12-24 Rowley Paul A Compositions and methods for inhibiting yeast infections
US20220111018A1 (en) * 2020-06-19 2022-04-14 University Of Idaho Compositions and methods for inhibiting yeast infections
CN111848740B (zh) * 2020-08-04 2023-03-24 南京市妇幼保健院 一种阴道分泌源性多肽及其在抑制白色念珠菌感染中的应用
EP4147716A1 (en) * 2021-09-10 2023-03-15 Samatva Research Corporation Anti-virus moiety immobilised in a matrix

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
AU669379B2 (en) * 1992-09-07 1996-06-06 Kyowa Hakko Kirin Co., Ltd. Humanized antibodies
WO1998008090A1 (en) * 1995-06-06 1998-02-26 Epigen, Inc. Anti-idiotypic antibodies to an epiglycanin
KR100259828B1 (ko) * 1995-09-11 2000-06-15 히라타 다다시 인체 인터루킨 5 수용체 알파-사슬에 대한 항체
DE69737188T2 (de) * 1996-05-04 2007-10-11 Astrazeneca Ab Monoklonaler antikoerper gegen cea, konjugate die dieses antikoerper enthalten und deren therapeutische verwendung in einem adept-system
ATE512225T1 (de) * 1998-04-03 2011-06-15 Chugai Pharmaceutical Co Ltd Humanisierter antikörper gegen den menschlichen gewebefaktor (tf) und verfahren für die konstruktion eines solchen humanisierten antikörpers.
JP2002529705A (ja) 1998-10-29 2002-09-10 コンネクス・ゲーエムベーハー 糞便中の耐酸性微生物を検出するための新規方法
CZ20012925A3 (cs) 1999-02-12 2002-01-16 Genetics Institute, Inc. Humanizovaný imunoglobulin reaktivní s B7 molekulami a způsob léčení
AU5250200A (en) * 1999-06-17 2001-01-09 Kyowa Hakko Kogyo Co. Ltd. Diagnostics and remedies for diseases with participation of macrocytes/macrophages
US7740841B1 (en) * 2000-01-28 2010-06-22 Sunnybrook Health Science Center Therapeutic method for reducing angiogenesis
EP1130032A1 (en) * 2000-02-28 2001-09-05 Gesellschaft für biotechnologische Forschung mbH (GBF) Single-chain antibodies recognizing the human vascular endothelial growth factor receptor-2 (VEGFR-2/KDR)
DE10019967A1 (de) * 2000-04-20 2001-10-25 Fenning Biomed Gmbh Dr Antikörper gegen natives gp96, deren Herstellung und Verwendung
AU2001271422B2 (en) * 2000-06-22 2005-12-22 Genentech, Inc. Agonist anti-trk-C monoclonal antibodies

Also Published As

Publication number Publication date
WO2003095493A2 (en) 2003-11-20
EP1504036A2 (en) 2005-02-09
NZ536957A (en) 2006-07-28
US20060280750A1 (en) 2006-12-14
AU2003233108A1 (en) 2003-11-11
US7722876B2 (en) 2010-05-25
CO7220324A2 (es) 2015-03-20
EP1504036B1 (en) 2011-06-29
GB0210783D0 (en) 2002-06-19
BR0309921A (pt) 2005-02-09
JP4405912B2 (ja) 2010-01-27
WO2003095493A3 (en) 2004-06-03
ATE514716T1 (de) 2011-07-15
JP2006506959A (ja) 2006-03-02
CA2484704A1 (en) 2003-11-20

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