EA201001190A1 - Выделенное антитело, специфически связанное с полипептидом, состоящее из последовательности аминокислотных остатков - Google Patents

Выделенное антитело, специфически связанное с полипептидом, состоящее из последовательности аминокислотных остатков

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Publication number
EA201001190A1
EA201001190A1 EA201001190A EA201001190A EA201001190A1 EA 201001190 A1 EA201001190 A1 EA 201001190A1 EA 201001190 A EA201001190 A EA 201001190A EA 201001190 A EA201001190 A EA 201001190A EA 201001190 A1 EA201001190 A1 EA 201001190A1
Authority
EA
Eurasian Patent Office
Prior art keywords
amino acid
sequence
acid number
polypeptide
seq
Prior art date
Application number
EA201001190A
Other languages
English (en)
Inventor
Скотт Р. Преснелл
Даррелл К. Конклин
Джулия Э. Новак
Анджела К. Хэммонд
Original Assignee
Займодженетикс, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Займодженетикс, Инк. filed Critical Займодженетикс, Инк.
Publication of EA201001190A1 publication Critical patent/EA201001190A1/ru

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Настоящее изобретение заявляет выделенное антитело, специфически связанное с полипептидом, состоящее из последовательности аминокислотных остатков, выбранных из группы, состоящей из последовательности от аминокислоты номер 20 (Cys) до аминокислоты номер 237 (His), как показано в SEQ ID NO:2; последовательности от аминокислоты номер 20 (Cys) до аминокислоты номер 255 (Leu), как показано в SEQ ID NO:2; последовательности от аминокислоты номер 256 (Lys) до аминокислоты номер 538 (Ser), как показано в SEQ ID NO:2, и последовательности от аминокислоты номер 20 (Cys) до аминокислоты номер 538 (Ser), как показано в SEQ ID NO:2, где антитело выбрано из группы, состоящей из моноклонального антитела, антигенсвязывающего домена, и созданного методами генной инженерии интактного антитела или домена, и гуманизированного антитела.
EA201001190A 1998-09-23 1999-09-23 Выделенное антитело, специфически связанное с полипептидом, состоящее из последовательности аминокислотных остатков EA201001190A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15925498A 1998-09-23 1998-09-23
US26511799A 1999-03-09 1999-03-09
US34793099A 1999-07-06 1999-07-06

Publications (1)

Publication Number Publication Date
EA201001190A1 true EA201001190A1 (ru) 2011-04-29

Family

ID=27388288

Family Applications (3)

Application Number Title Priority Date Filing Date
EA200100276A EA006501B1 (ru) 1998-09-23 1999-09-23 Полипептиды zalpha 11 рецептора цитокина человека класса i, кодирующие их полинуклеотиды и способы их применения
EA201001190A EA201001190A1 (ru) 1998-09-23 1999-09-23 Выделенное антитело, специфически связанное с полипептидом, состоящее из последовательности аминокислотных остатков
EA200501461A EA014417B1 (ru) 1998-09-23 1999-09-23 Экспрессирующий вектор, содержащий полинуклеотид, кодирующий зрелый полипептид zalpha11 рецептора цитокина человека класса i или его функциональные компоненты, культивируемые клетки, содержащие экспрессирующий вектор, способ получения зрелого полипептида zalpha11 или его функциональных компонентов, полипептид, полученный данным способом, антитело, которое связывается с полипептидом, и полинуклеотид, кодирующий полипептид

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EA200100276A EA006501B1 (ru) 1998-09-23 1999-09-23 Полипептиды zalpha 11 рецептора цитокина человека класса i, кодирующие их полинуклеотиды и способы их применения

Family Applications After (1)

Application Number Title Priority Date Filing Date
EA200501461A EA014417B1 (ru) 1998-09-23 1999-09-23 Экспрессирующий вектор, содержащий полинуклеотид, кодирующий зрелый полипептид zalpha11 рецептора цитокина человека класса i или его функциональные компоненты, культивируемые клетки, содержащие экспрессирующий вектор, способ получения зрелого полипептида zalpha11 или его функциональных компонентов, полипептид, полученный данным способом, антитело, которое связывается с полипептидом, и полинуклеотид, кодирующий полипептид

Country Status (18)

Country Link
EP (2) EP2105446B1 (ru)
JP (2) JP4704565B2 (ru)
KR (1) KR20010085838A (ru)
CN (1) CN1344320A (ru)
AU (1) AU772172B2 (ru)
BR (1) BR9913942A (ru)
CA (1) CA2343839C (ru)
CZ (1) CZ20011026A3 (ru)
DE (1) DE69941126D1 (ru)
DK (1) DK1115862T3 (ru)
EA (3) EA006501B1 (ru)
ES (1) ES2329741T3 (ru)
HU (1) HUP0103593A2 (ru)
IL (3) IL142164A0 (ru)
NO (1) NO20011460L (ru)
NZ (1) NZ510744A (ru)
PL (1) PL349068A1 (ru)
WO (1) WO2000017235A2 (ru)

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Also Published As

Publication number Publication date
WO2000017235A2 (en) 2000-03-30
BR9913942A (pt) 2001-10-16
CZ20011026A3 (cs) 2001-08-15
IL142164A (en) 2009-09-22
ES2329741T3 (es) 2009-11-30
NO20011460L (no) 2001-05-23
CA2343839C (en) 2012-09-11
EP2105446B1 (en) 2013-08-14
EP2105446A2 (en) 2009-09-30
EP1115862B1 (en) 2009-07-15
JP2002526062A (ja) 2002-08-20
JP4704565B2 (ja) 2011-06-15
AU6499899A (en) 2000-04-10
DE69941126D1 (de) 2009-08-27
PL349068A1 (en) 2002-07-01
EP1115862A2 (en) 2001-07-18
HUP0103593A2 (hu) 2002-01-28
JP2011015700A (ja) 2011-01-27
EP2105446A3 (en) 2010-07-07
EA200100276A1 (ru) 2001-10-22
NO20011460D0 (no) 2001-03-22
DK1115862T3 (da) 2009-11-16
WO2000017235A3 (en) 2000-07-20
IL185764A (en) 2010-06-16
CN1344320A (zh) 2002-04-10
IL185764A0 (en) 2008-01-06
AU772172B2 (en) 2004-04-08
EA200501461A1 (ru) 2006-02-24
KR20010085838A (ko) 2001-09-07
NZ510744A (en) 2003-02-28
EA014417B1 (ru) 2010-12-30
EA006501B1 (ru) 2005-12-29
IL142164A0 (en) 2002-03-10
CA2343839A1 (en) 2000-03-30

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