NO20011460L - Cytokinreseptor zalphall - Google Patents

Cytokinreseptor zalphall

Info

Publication number
NO20011460L
NO20011460L NO20011460A NO20011460A NO20011460L NO 20011460 L NO20011460 L NO 20011460L NO 20011460 A NO20011460 A NO 20011460A NO 20011460 A NO20011460 A NO 20011460A NO 20011460 L NO20011460 L NO 20011460L
Authority
NO
Norway
Prior art keywords
polypeptides
methods
cytokine receptor
vitro
vivo
Prior art date
Application number
NO20011460A
Other languages
English (en)
Other versions
NO20011460D0 (no
Inventor
Scott R Presnell
Darrell C Conklin
Julia E Novak
Angela K Hammond
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Publication of NO20011460D0 publication Critical patent/NO20011460D0/no
Publication of NO20011460L publication Critical patent/NO20011460L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Nye polypeptider, polynukleotider som koder for polypeptidene, og beslek- tede preparater og fremgangsmåter er beskrevet for zalphall, en ny cytokin- reseptor. Polypeptidene kan anvendes i fremgangsmåter for påvisning av Ugander som stimulerer proliferasjonen og/eller utviklingen av hematopoese-, lymfoid- og myeloidceller in vitro og in vivo. Ligandbindende reseptorpoly- peptider kan også brukes til å blokkere ligandaktivitet in vitro og in vivo. Polynukleotidene som koder for zalpha- ll, befinner seg på kromosom 16 og kan brukes for å identifisere en region i genomet som er forbundet med human- sykdomstilstander. Foreliggende opp- finnelse omfatter også fremgangsmåter for fremstilling av proteinet, anven- delser av det og antistoffer mot det.
NO20011460A 1998-09-23 2001-03-22 Cytokinreseptor zalphall NO20011460L (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US15925498A 1998-09-23 1998-09-23
US26511799A 1999-03-09 1999-03-09
US34793099A 1999-07-06 1999-07-06
PCT/US1999/022149 WO2000017235A2 (en) 1998-09-23 1999-09-23 Cytokine receptor zalpha11

Publications (2)

Publication Number Publication Date
NO20011460D0 NO20011460D0 (no) 2001-03-22
NO20011460L true NO20011460L (no) 2001-05-23

Family

ID=27388288

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20011460A NO20011460L (no) 1998-09-23 2001-03-22 Cytokinreseptor zalphall

Country Status (18)

Country Link
EP (2) EP2105446B1 (no)
JP (2) JP4704565B2 (no)
KR (1) KR20010085838A (no)
CN (1) CN1344320A (no)
AU (1) AU772172B2 (no)
BR (1) BR9913942A (no)
CA (1) CA2343839C (no)
CZ (1) CZ20011026A3 (no)
DE (1) DE69941126D1 (no)
DK (1) DK1115862T3 (no)
EA (3) EA014417B1 (no)
ES (1) ES2329741T3 (no)
HU (1) HUP0103593A2 (no)
IL (3) IL142164A0 (no)
NO (1) NO20011460L (no)
NZ (1) NZ510744A (no)
PL (1) PL349068A1 (no)
WO (1) WO2000017235A2 (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7198789B2 (en) 1998-03-17 2007-04-03 Genetics Institute, Llc Methods and compositions for modulating interleukin-21 receptor activity
US6057128A (en) 1998-03-17 2000-05-02 Genetics Institute, Inc. MU-1, member of the cytokine receptor family
US7189400B2 (en) 1998-03-17 2007-03-13 Genetics Institute, Llc Methods of treatment with antagonists of MU-1
US6803451B2 (en) 1998-09-23 2004-10-12 Zymogenetics, Inc. Cytokine receptor zalpha11 polypeptides
US6576744B1 (en) * 1998-09-23 2003-06-10 Zymogenetics, Inc. Cytokine receptor zalpha11
DE60125543T2 (de) 2000-04-05 2007-10-04 Zymogenetics, Inc., Seattle Löslicher zytokinrezeptor zalpha11
CN1320611A (zh) * 2000-04-27 2001-11-07 上海博德基因开发有限公司 一种新的多肽——细胞因子受体15和编码这种多肽的多核苷酸
EP1353953B1 (en) * 2000-05-11 2006-11-29 Genetics Institute, LLC Mu-1, member of the cytokine receptor family
JP4619580B2 (ja) * 2001-07-30 2011-01-26 デンカ生研株式会社 抗体捕捉法による抗体の免疫学的測定方法
EP1432431B1 (en) * 2001-10-04 2017-05-10 Genetics Institute LLC Methods and compositions for modulating interleukin-21 activity
JP2006514601A (ja) 2002-06-07 2006-05-11 ザイモジェネティクス インコーポレイティッド ガンおよびその他の治療用途におけるｉｌ−２１の使用方法
WO2004003156A2 (en) 2002-07-01 2004-01-08 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Il-21 as a regulator of immunoglobin production
CA2491320A1 (en) 2002-07-15 2004-01-22 Wyeth Methods and compositions for modulating t helper (th) cell development and function
NZ542306A (en) 2003-03-14 2008-04-30 Wyeth Corp Antibodies against human IL-21 receptor and uses therefor
WO2013169693A1 (en) 2012-05-09 2013-11-14 Bristol-Myers Squibb Company Methods of treating cancer using an il-21 polypeptide and an anti-pd-1 antibody
GB201810181D0 (en) * 2018-06-21 2018-08-08 Immetacyte Ltd Cells expressing chimeric recominant growth factor receptors
US12012441B2 (en) 2020-10-26 2024-06-18 Neptune Biosciences Llc Engineered human IL-21 cytokines and methods for using the same

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU560472B2 (en) 1981-08-25 1987-04-09 Celltech Limited Yeast expression vectors
US4579821A (en) 1981-11-23 1986-04-01 University Patents, Inc. Control of DNA sequence transcription
US4656134A (en) 1982-01-11 1987-04-07 Board Of Trustees Of Leland Stanford Jr. University Gene amplification in eukaryotic cells
US4486533A (en) 1982-09-02 1984-12-04 St. Louis University Filamentous fungi functional replicating extrachromosomal element
US4599311A (en) 1982-08-13 1986-07-08 Kawasaki Glenn H Glycolytic promotersfor regulated protein expression: protease inhibitor
US4977092A (en) 1985-06-26 1990-12-11 Amgen Expression of exogenous polypeptides and polypeptide products including hepatitis B surface antigen in yeast cells
US4601978A (en) 1982-11-24 1986-07-22 The Regents Of The University Of California Mammalian metallothionein promoter system
US4713339A (en) 1983-01-19 1987-12-15 Genentech, Inc. Polycistronic expression vector construction
US4661454A (en) 1983-02-28 1987-04-28 Collaborative Research, Inc. GAL1 yeast promoter linked to non galactokinase gene
US5139936A (en) 1983-02-28 1992-08-18 Collaborative Research, Inc. Use of the GAL1 yeast promoter
US4650764A (en) 1983-04-12 1987-03-17 Wisconsin Alumni Research Foundation Helper cell
US4870008A (en) 1983-08-12 1989-09-26 Chiron Corporation Secretory expression in eukaryotes
US4931373A (en) 1984-05-25 1990-06-05 Zymogenetics, Inc. Stable DNA constructs for expression of α-1 antitrypsin
US4766073A (en) 1985-02-25 1988-08-23 Zymogenetics Inc. Expression of biologically active PDGF analogs in eucaryotic cells
EP0184576B1 (en) 1984-12-06 1990-06-27 Fina Research S.A. Promoters for the expression of foreign genes in yeast, plasmids comprising them, and uses thereof for the production of polypeptides
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
GR860984B (en) 1985-04-17 1986-08-18 Zymogenetics Inc Expression of factor vii and ix activities in mammalian cells
US4882279A (en) 1985-10-25 1989-11-21 Phillips Petroleum Company Site selective genomic modification of yeast of the genus pichia
US4935349A (en) 1986-01-17 1990-06-19 Zymogenetics, Inc. Expression of higher eucaryotic genes in aspergillus
GB8611832D0 (en) 1986-05-15 1986-06-25 Holland I B Polypeptide
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US4980289A (en) 1987-04-27 1990-12-25 Wisconsin Alumni Research Foundation Promoter deficient retroviral vector
US5063154A (en) 1987-06-24 1991-11-05 Whitehead Institute For Biomedical Research Pheromone - inducible yeast promoter
ATE140963T1 (de) 1988-01-22 1996-08-15 Zymogenetics Inc Verfahren zur herstellung von sekretierten rezeptoranalogen
US5567584A (en) 1988-01-22 1996-10-22 Zymogenetics, Inc. Methods of using biologically active dimerized polypeptide fusions to detect PDGF
US4956288A (en) 1988-04-22 1990-09-11 Biogen, Inc. Method for producing cells containing stably integrated foreign DNA at a high copy number, the cells produced by this method, and the use of these cells to produce the polypeptides coded for by the foreign DNA
US5037743A (en) 1988-08-05 1991-08-06 Zymogenetics, Inc. BAR1 secretion signal
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US5162228A (en) 1988-12-28 1992-11-10 Takeda Chemical Industries, Ltd. Gylceraldehyde-3-phosphate dehydrogenase gene and promoter
US5124263A (en) 1989-01-12 1992-06-23 Wisconsin Alumni Research Foundation Recombination resistant retroviral helper cell and products produced thereby
US5399346A (en) 1989-06-14 1995-03-21 The United States Of America As Represented By The Department Of Health And Human Services Gene therapy
US5162222A (en) 1989-07-07 1992-11-10 Guarino Linda A Use of baculovirus early promoters for expression of foreign genes in stably transformed insect cells or recombinant baculoviruses
NL9002116A (nl) 1990-09-27 1992-04-16 Clovis Matton N V Werkwijze voor het genetisch manipuleren van plantecellen, recombinante plasmiden, recombinante bacterien, planten.
WO1992010570A1 (en) 1990-12-13 1992-06-25 Immunex Corporation Leukemia inhibitory factor receptors
US5298418A (en) 1991-09-16 1994-03-29 Boyce Thompson Institute For Plant Research, Inc. Cell line isolated from larval midgut tissue of Trichoplusia ni
CA2144651A1 (en) 1992-09-14 1994-03-31 Timothy J. Miller Immortalized cells and uses therefor
WO1995002684A1 (en) * 1993-07-16 1995-01-26 The Board Of Trustees Of The Leland Stanford Junior University Regulated apoptosis
WO1995007358A1 (en) 1993-07-30 1995-03-16 University Of Medicine & Dentistry Of New Jersey Efficient gene transfer into primary lymphocytes
WO1995021930A2 (en) 1994-02-14 1995-08-17 Zymogenetics, Inc. Method for preparing orphan receptor ligands
US6117679A (en) 1994-02-17 2000-09-12 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
KR100384249B1 (ko) * 1994-08-02 2003-08-30 더 제너럴 하스피탈 코포레이션 Cd4 디코이 수용체 포함세포 및 관련 분자 및 방법
PT871495E (pt) * 1995-02-24 2005-10-31 Gen Hospital Corp Redireccionamento de imunidade celular atraves de receptores quimericos
CA2237120C (en) 1995-11-09 2005-03-01 Zymogenetics, Inc. Compositions and methods for producing heterologous polypeptides in pichia methanolica
AU718510B2 (en) 1996-07-17 2000-04-13 Zymogenetics Inc. Transformation of pichia methanolica
CN1238806A (zh) 1996-07-17 1999-12-15 津莫吉尼蒂克斯公司 甲醇毕赤酵母营养突变体的制备
AU5733898A (en) * 1997-01-16 1998-08-07 Genetics Institute Inc. Member of the hematopoietin receptor superfamily
US6057128A (en) * 1998-03-17 2000-05-02 Genetics Institute, Inc. MU-1, member of the cytokine receptor family
CA2330547A1 (en) * 1998-06-24 1999-12-29 Chugai Research Institute For Molecular Medicine, Inc. Novel hemopoietin receptor proteins
AU5104799A (en) * 1998-08-04 2000-02-28 Regeneron Pharmaceuticals, Inc. Novel orphan cytokine receptors

Also Published As

Publication number Publication date
JP4704565B2 (ja) 2011-06-15
JP2002526062A (ja) 2002-08-20
NO20011460D0 (no) 2001-03-22
CA2343839C (en) 2012-09-11
CA2343839A1 (en) 2000-03-30
DK1115862T3 (da) 2009-11-16
IL185764A0 (en) 2008-01-06
PL349068A1 (en) 2002-07-01
IL185764A (en) 2010-06-16
AU772172B2 (en) 2004-04-08
EA014417B1 (ru) 2010-12-30
IL142164A0 (en) 2002-03-10
ES2329741T3 (es) 2009-11-30
EA200100276A1 (ru) 2001-10-22
EP1115862A2 (en) 2001-07-18
NZ510744A (en) 2003-02-28
CN1344320A (zh) 2002-04-10
DE69941126D1 (de) 2009-08-27
WO2000017235A3 (en) 2000-07-20
EP2105446A2 (en) 2009-09-30
AU6499899A (en) 2000-04-10
EA201001190A1 (ru) 2011-04-29
EA006501B1 (ru) 2005-12-29
KR20010085838A (ko) 2001-09-07
EP2105446B1 (en) 2013-08-14
EP2105446A3 (en) 2010-07-07
WO2000017235A2 (en) 2000-03-30
EP1115862B1 (en) 2009-07-15
IL142164A (en) 2009-09-22
CZ20011026A3 (cs) 2001-08-15
BR9913942A (pt) 2001-10-16
HUP0103593A2 (hu) 2002-01-28
JP2011015700A (ja) 2011-01-27
EA200501461A1 (ru) 2006-02-24

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FC2A Withdrawal, rejection or dismissal of laid open patent application