HUP0301921A2 - Elnyújtott hatóanyag-leadású készítmények hidrofil vegyületek parenterális adagolására - Google Patents

Elnyújtott hatóanyag-leadású készítmények hidrofil vegyületek parenterális adagolására

Info

Publication number
HUP0301921A2
HUP0301921A2 HU0301921A HUP0301921A HUP0301921A2 HU P0301921 A2 HUP0301921 A2 HU P0301921A2 HU 0301921 A HU0301921 A HU 0301921A HU P0301921 A HUP0301921 A HU P0301921A HU P0301921 A2 HUP0301921 A2 HU P0301921A2
Authority
HU
Hungary
Prior art keywords
hydrophilic
sustained release
pharmaceutical compositions
release pharmaceutical
hydrophilic compounds
Prior art date
Application number
HU0301921A
Other languages
English (en)
Inventor
Francesco Autuori
Carlo Bianchini
Giuseppe Bottoni
Flavio Leoni
Paolo Mascagni
Walmen Monzani
Oreste Piccolo
Original Assignee
Italfarmaco S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Italfarmaco S.P.A. filed Critical Italfarmaco S.P.A.
Publication of HUP0301921A2 publication Critical patent/HUP0301921A2/hu
Publication of HUP0301921A3 publication Critical patent/HUP0301921A3/hu
Publication of HU228926B1 publication Critical patent/HU228926B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A találmány tárgya stabil, biológiailag kompatibilis, jól tolerálhatóv/o mikroemulzió, amely alkalmas hidrofil vagy megfelelő eljárássalhidrofillé alakított biológiailag aktív vegyületek parenterálisadagolására, amely biztosítja az aktív vegyületek tartósfelszabadulását, ahol a mikroemulzió az alábbiakat tartalmazza: a)20%-ig terjedő mennyiségben egy belső hidrofil vizes fázis, ami aterápiásan hatékony hidrofil vegyületet tartalmazza; b) 30-98%mennyiségben egy hidrofób külső fázis; c) 50%-ig terjedő mennyiségbenfelületaktív anyag olyan segéd felületaktív anyaggal keverve, amely azalábbiak közül választott: C8-20 zsírsavak; C2-14 polihidroxi-alkánok;C2-12 alkoholok; C2-8 alkoholmaradékkal képzett tejsavészterek. Ó
HU0301921A 2000-05-26 2001-05-23 Sustained release pharmaceutical compositions for paranteral administration of hydrophilic compounds HU228926B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2000MI001173A IT1318539B1 (it) 2000-05-26 2000-05-26 Composizioni farmaceutiche a rilascio prolungato per lasomministrazione parenterale di sostanze idrofile biologicamente
PCT/EP2001/005949 WO2001089479A2 (en) 2000-05-26 2001-05-23 Sustained release pharmaceutical compositions for parenteral administration of hydrophilic compounds

Publications (3)

Publication Number Publication Date
HUP0301921A2 true HUP0301921A2 (hu) 2003-09-29
HUP0301921A3 HUP0301921A3 (en) 2005-11-28
HU228926B1 HU228926B1 (en) 2013-06-28

Family

ID=11445131

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0301921A HU228926B1 (en) 2000-05-26 2001-05-23 Sustained release pharmaceutical compositions for paranteral administration of hydrophilic compounds

Country Status (28)

Country Link
US (1) US7157099B2 (hu)
EP (1) EP1283700B1 (hu)
JP (1) JP4954423B2 (hu)
KR (1) KR100802625B1 (hu)
CN (1) CN100479856C (hu)
AT (1) ATE321533T1 (hu)
AU (2) AU8178601A (hu)
BR (1) BRPI0111016B8 (hu)
CA (1) CA2409854C (hu)
CY (1) CY1105262T1 (hu)
CZ (1) CZ302059B6 (hu)
DE (1) DE60118395T2 (hu)
DK (1) DK1283700T3 (hu)
ES (1) ES2257428T3 (hu)
HR (1) HRP20020929A2 (hu)
HU (1) HU228926B1 (hu)
IL (1) IL153011A0 (hu)
IT (1) IT1318539B1 (hu)
MX (1) MXPA02011539A (hu)
NO (1) NO334880B1 (hu)
PL (1) PL203354B1 (hu)
PT (1) PT1283700E (hu)
RU (1) RU2272615C2 (hu)
SI (1) SI1283700T1 (hu)
SK (1) SK16552002A3 (hu)
WO (1) WO2001089479A2 (hu)
YU (1) YU88202A (hu)
ZA (1) ZA200209520B (hu)

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WO2001089479A2 (en) 2001-11-29
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AU2001281786B8 (en) 2005-11-17
EP1283700B1 (en) 2006-03-29
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JP2003534265A (ja) 2003-11-18
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HUP0301921A3 (en) 2005-11-28
WO2001089479A3 (en) 2002-03-28
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