HUP0000299A1 - Késleltetett hatóanyag-leadású gyógyszerkészítmények - Google Patents

Késleltetett hatóanyag-leadású gyógyszerkészítmények

Info

Publication number
HUP0000299A1
HUP0000299A1 HU0000299A HUP0000299A HUP0000299A1 HU P0000299 A1 HUP0000299 A1 HU P0000299A1 HU 0000299 A HU0000299 A HU 0000299A HU P0000299 A HUP0000299 A HU P0000299A HU P0000299 A1 HUP0000299 A1 HU P0000299A1
Authority
HU
Hungary
Prior art keywords
drug delivery
pharmaceutical formulations
sustained drug
macromolecule
refractory
Prior art date
Application number
HU0000299A
Other languages
English (en)
Inventor
Nicholas Barker
Malcolm L. Gefter
Christopher J. Molineaux
Gary Musso
Original Assignee
Praecis Pharmaceuticals Incorporated
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Praecis Pharmaceuticals Incorporated filed Critical Praecis Pharmaceuticals Incorporated
Publication of HUP0000299A1 publication Critical patent/HUP0000299A1/hu
Publication of HUP0000299A3 publication Critical patent/HUP0000299A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones

Abstract

A találmány tárgya gyógyszerkészítmény, amely egy gyógyászatilaghatásős peptid és egy hőrdőzó makrőmőlekűla szilárd iőnős kőmplexéttartalmazza. A találmány szerinti gyógyszerkészítmény LHRH-analógőkkalkezelhető betegségek kezelésében alkalmazható. ŕ
HU0000299A 1996-12-11 1997-12-11 Pharmaceutical formulations for sustained drug delivery HUP0000299A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/762,747 US5968895A (en) 1996-12-11 1996-12-11 Pharmaceutical formulations for sustained drug delivery
PCT/US1997/022881 WO1998025642A2 (en) 1996-12-11 1997-12-11 Pharmaceutical formulations comprising a water-insoluble complex for sustained drug delivery

Publications (2)

Publication Number Publication Date
HUP0000299A1 true HUP0000299A1 (hu) 2000-06-28
HUP0000299A3 HUP0000299A3 (en) 2000-09-28

Family

ID=25065930

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0000299A HUP0000299A3 (en) 1996-12-11 1997-12-11 Pharmaceutical formulations for sustained drug delivery

Country Status (35)

Country Link
US (4) US5968895A (hu)
EP (4) EP1398037B1 (hu)
JP (3) JP4033498B2 (hu)
KR (2) KR101114618B1 (hu)
CN (2) CN100522239C (hu)
AR (1) AR010351A1 (hu)
AT (3) ATE378059T1 (hu)
AU (1) AU735174B2 (hu)
BR (1) BR9714015A (hu)
CA (1) CA2274847A1 (hu)
CO (1) CO4910114A1 (hu)
CZ (1) CZ301119B6 (hu)
DE (2) DE69738300T2 (hu)
DK (1) DK1398037T3 (hu)
DZ (1) DZ2371A1 (hu)
ES (1) ES2299192T3 (hu)
HK (2) HK1023282A1 (hu)
HR (1) HRP970674A2 (hu)
HU (1) HUP0000299A3 (hu)
IL (3) IL130309A (hu)
JO (1) JO1998B1 (hu)
MA (1) MA26456A1 (hu)
NZ (4) NZ579443A (hu)
PE (1) PE20000008A1 (hu)
PL (2) PL199121B1 (hu)
PT (1) PT952843E (hu)
RU (1) RU2202371C2 (hu)
SI (1) SI0952843T1 (hu)
SK (1) SK287305B6 (hu)
TN (1) TNSN97205A1 (hu)
TR (1) TR199901382T2 (hu)
UA (1) UA68343C2 (hu)
UY (2) UY24806A1 (hu)
WO (1) WO1998025642A2 (hu)
ZA (1) ZA9710994B (hu)

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