HUE054855T2 - 191P4D12 fehérjékhez kötõdõ antitest-gyógyszer konjugátumok (ADC) - Google Patents

191P4D12 fehérjékhez kötõdõ antitest-gyógyszer konjugátumok (ADC)

Info

Publication number
HUE054855T2
HUE054855T2 HUE18171803A HUE18171803A HUE054855T2 HU E054855 T2 HUE054855 T2 HU E054855T2 HU E18171803 A HUE18171803 A HU E18171803A HU E18171803 A HUE18171803 A HU E18171803A HU E054855 T2 HUE054855 T2 HU E054855T2
Authority
HU
Hungary
Prior art keywords
adc
bind
proteins
drug conjugates
antibody drug
Prior art date
Application number
HUE18171803A
Other languages
English (en)
Hungarian (hu)
Inventor
Daulet Satpaev
Robert Kendall Morrison
Karen Jane Meyrick Morrison
Jean Gudas
Aya Jakobovits
Michael Torgov
Zili An
Original Assignee
Agensys Inc
Seagen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45871300&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUE054855(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Agensys Inc, Seagen Inc filed Critical Agensys Inc
Publication of HUE054855T2 publication Critical patent/HUE054855T2/hu

Links

Classifications

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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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