MX2013003419A - Conjugados de anticuerpo farmaco (adc) que enlazan a proteinas 191p4d12. - Google Patents
Conjugados de anticuerpo farmaco (adc) que enlazan a proteinas 191p4d12.Info
- Publication number
- MX2013003419A MX2013003419A MX2013003419A MX2013003419A MX2013003419A MX 2013003419 A MX2013003419 A MX 2013003419A MX 2013003419 A MX2013003419 A MX 2013003419A MX 2013003419 A MX2013003419 A MX 2013003419A MX 2013003419 A MX2013003419 A MX 2013003419A
- Authority
- MX
- Mexico
- Prior art keywords
- adc
- bind
- drug conjugates
- antibody drug
- proteins
- Prior art date
Links
- 229940049595 antibody-drug conjugate Drugs 0.000 title abstract 4
- 239000000611 antibody drug conjugate Substances 0.000 title abstract 2
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 201000011510 cancer Diseases 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
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Abstract
Se describen en la presente conjugados de anticuerpo fármaco (ADC's) que enlazan a la proteína 191P4D12 y variantes de la misma. La 191P4D12 exhibe expresión específica de tejido en el tejido adulto normal, y se expresa aberrantemente en los cánceres listados en la Tabla I. Consecuentemente, los ADC's de la invención proporcionan una composición terapéutica para el tratamiento de cáncer.
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US38793310P | 2010-09-29 | 2010-09-29 | |
PCT/US2011/054054 WO2012047724A1 (en) | 2010-09-29 | 2011-09-29 | Antibody drug conjugates (adc) that bind to 191p4d12 proteins |
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MX2013003419A true MX2013003419A (es) | 2014-04-14 |
MX337873B MX337873B (es) | 2016-03-23 |
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MX2016003743A MX347954B (es) | 2010-09-29 | 2011-09-29 | Conjugados de anticuerpo farmaco (adc) que enlazan a proteinas 191p4d12. |
MX2013003419A MX337873B (es) | 2010-09-29 | 2011-09-29 | Conjugados de anticuerpo farmaco (adc) que enlazan a proteinas 191p4d12. |
MX2017006479A MX369679B (es) | 2010-09-29 | 2011-09-29 | Conjugados de anticuerpo fármaco (adc) que enlazan a proteínas 191p4d12. |
MX2019013655A MX2019013655A (es) | 2010-09-29 | 2013-03-22 | Conjugados de anticuerpo farmaco (adc) que enlazan a proteinas 191p4d12. |
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MX2016003743A MX347954B (es) | 2010-09-29 | 2011-09-29 | Conjugados de anticuerpo farmaco (adc) que enlazan a proteinas 191p4d12. |
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MX2017006479A MX369679B (es) | 2010-09-29 | 2011-09-29 | Conjugados de anticuerpo fármaco (adc) que enlazan a proteínas 191p4d12. |
MX2019013655A MX2019013655A (es) | 2010-09-29 | 2013-03-22 | Conjugados de anticuerpo farmaco (adc) que enlazan a proteinas 191p4d12. |
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US (8) | US8637642B2 (es) |
EP (3) | EP3903812A1 (es) |
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CN (2) | CN105567717B (es) |
AU (1) | AU2011312417B2 (es) |
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