MA52135A - Utilisation de conjugués anticorps-médicament comprenant des agents de rupture de tubuline pour traiter une tumeur solide - Google Patents
Utilisation de conjugués anticorps-médicament comprenant des agents de rupture de tubuline pour traiter une tumeur solideInfo
- Publication number
- MA52135A MA52135A MA052135A MA52135A MA52135A MA 52135 A MA52135 A MA 52135A MA 052135 A MA052135 A MA 052135A MA 52135 A MA52135 A MA 52135A MA 52135 A MA52135 A MA 52135A
- Authority
- MA
- Morocco
- Prior art keywords
- antibody
- treat
- solid tumor
- drug conjugates
- conjugates including
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 102000004243 Tubulin Human genes 0.000 title 1
- 108090000704 Tubulin Proteins 0.000 title 1
- 239000000611 antibody drug conjugate Substances 0.000 title 1
- 229940049595 antibody-drug conjugate Drugs 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 title 1
Classifications
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- A61K47/6889—Conjugates wherein the antibody being the modifying agent and wherein the linker, binder or spacer confers particular properties to the conjugates, e.g. peptidic enzyme-labile linkers or acid-labile linkers, providing for an acid-labile immuno conjugate wherein the drug may be released from its antibody conjugated part in an acidic, e.g. tumoural or environment
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- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3076—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties
- C07K16/3084—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties against tumour-associated gangliosides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Emergency Medicine (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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US201862647346P | 2018-03-23 | 2018-03-23 | |
US201862658276P | 2018-04-16 | 2018-04-16 |
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MA52135A true MA52135A (fr) | 2021-01-27 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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MA052135A MA52135A (fr) | 2018-03-23 | 2019-03-22 | Utilisation de conjugués anticorps-médicament comprenant des agents de rupture de tubuline pour traiter une tumeur solide |
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US (2) | US20190290775A1 (fr) |
EP (1) | EP3768714A1 (fr) |
JP (2) | JP2021518397A (fr) |
KR (1) | KR20200135841A (fr) |
CN (1) | CN112189020A (fr) |
AU (1) | AU2019240403A1 (fr) |
BR (1) | BR112020018948A2 (fr) |
CA (1) | CA3093731A1 (fr) |
IL (1) | IL277338A (fr) |
MA (1) | MA52135A (fr) |
MX (1) | MX2020009842A (fr) |
SG (1) | SG11202009264WA (fr) |
TW (1) | TW202003047A (fr) |
WO (1) | WO2019183438A1 (fr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
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JP7560575B2 (ja) | 2020-05-03 | 2024-10-02 | シャンハイ ミラコーケン インコーポレイティド | 抗体-薬物コンジュゲート及びその調製物 |
CA3185666A1 (fr) * | 2020-06-19 | 2021-12-23 | Agensys, Inc. | Marqueurs destines a etre utilises dans des methodes de traitement de cancers avec des conjugues anticorps-medicaments (adc) |
CA3197158A1 (fr) * | 2020-09-28 | 2022-03-31 | Seagen Inc. | Anticorps anti-liv1 humanises destines au traitement du cancer |
EP4308170A1 (fr) | 2021-03-18 | 2024-01-24 | Seagen Inc. | Libération sélective de médicament à partir de conjugués internalisés de composés biologiquement actifs |
EP4423135A1 (fr) | 2021-10-29 | 2024-09-04 | Seagen Inc. | Méthodes de traitement du cancer à l'aide d'une association d'un anticorps anti-pd-1 et d'un conjugué anticorps anti-cd30-médicament |
WO2024179453A1 (fr) * | 2023-02-27 | 2024-09-06 | 石药集团巨石生物制药有限公司 | Composition pharmaceutique d'un médicament conjugué mmae-anticorps monoclonal anti-nectine-4 humanisé recombinant |
WO2024194774A1 (fr) * | 2023-03-17 | 2024-09-26 | Zydus Lifesciences Limited | Conjugués médicamenteux de daratumumab et leur préparation |
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JPS55162791A (en) | 1979-06-05 | 1980-12-18 | Takeda Chem Ind Ltd | Antibiotic c-15003pnd and its preparation |
JPS5645483A (en) | 1979-09-19 | 1981-04-25 | Takeda Chem Ind Ltd | C-15003phm and its preparation |
JPS5645485A (en) | 1979-09-21 | 1981-04-25 | Takeda Chem Ind Ltd | Production of c-15003pnd |
EP0028683A1 (fr) | 1979-09-21 | 1981-05-20 | Takeda Chemical Industries, Ltd. | Antibiotique C-15003 PHO et sa préparation |
WO1982001188A1 (fr) | 1980-10-08 | 1982-04-15 | Takeda Chemical Industries Ltd | Composes 4,5-deoxymaytansinoide et leur procede de preparation |
US4450254A (en) | 1980-11-03 | 1984-05-22 | Standard Oil Company | Impact improvement of high nitrile resins |
US4313946A (en) | 1981-01-27 | 1982-02-02 | The United States Of America As Represented By The Secretary Of Agriculture | Chemotherapeutically active maytansinoids from Trewia nudiflora |
US4315929A (en) | 1981-01-27 | 1982-02-16 | The United States Of America As Represented By The Secretary Of Agriculture | Method of controlling the European corn borer with trewiasine |
JPS57192389A (en) | 1981-05-20 | 1982-11-26 | Takeda Chem Ind Ltd | Novel maytansinoid |
US4714681A (en) | 1981-07-01 | 1987-12-22 | The Board Of Reagents, The University Of Texas System Cancer Center | Quadroma cells and trioma cells and methods for the production of same |
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FI102355B1 (fi) | 1988-02-11 | 1998-11-30 | Bristol Myers Squibb Co | Menetelmä yhdistävän välikappaleen omaavien antrasykliini-immunokonjugaattien valmistamiseksi |
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CA2452130A1 (fr) | 1992-03-05 | 1993-09-16 | Francis J. Burrows | Agents diagnostiques et/ou therapeutiques cibles pour les cellules endotheliales neovasculaires |
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PT3900742T (pt) | 2014-09-11 | 2024-08-21 | Seagen Inc | Entrega direcionada de fármacos contendo uma amina terciária |
BR112017023862A2 (pt) * | 2015-05-04 | 2018-07-17 | Cytomx Therapeutics Inc | anticorpos anti-cd71, anticorpos anti-cd71 ativáveis, e métodos de uso destes |
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2019
- 2019-03-22 AU AU2019240403A patent/AU2019240403A1/en active Pending
- 2019-03-22 BR BR112020018948-0A patent/BR112020018948A2/pt not_active Application Discontinuation
- 2019-03-22 WO PCT/US2019/023516 patent/WO2019183438A1/fr active Application Filing
- 2019-03-22 TW TW108109929A patent/TW202003047A/zh unknown
- 2019-03-22 MX MX2020009842A patent/MX2020009842A/es unknown
- 2019-03-22 SG SG11202009264WA patent/SG11202009264WA/en unknown
- 2019-03-22 MA MA052135A patent/MA52135A/fr unknown
- 2019-03-22 KR KR1020207030320A patent/KR20200135841A/ko not_active Application Discontinuation
- 2019-03-22 US US16/362,125 patent/US20190290775A1/en not_active Abandoned
- 2019-03-22 CA CA3093731A patent/CA3093731A1/fr active Pending
- 2019-03-22 JP JP2020550674A patent/JP2021518397A/ja active Pending
- 2019-03-22 EP EP19715720.9A patent/EP3768714A1/fr active Pending
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2020
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2022
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2024
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KR20200135841A (ko) | 2020-12-03 |
SG11202009264WA (en) | 2020-10-29 |
MX2020009842A (es) | 2020-10-15 |
JP2021518397A (ja) | 2021-08-02 |
BR112020018948A2 (pt) | 2021-01-05 |
WO2019183438A1 (fr) | 2019-09-26 |
JP2024075771A (ja) | 2024-06-04 |
IL277338A (en) | 2020-10-29 |
EP3768714A1 (fr) | 2021-01-27 |
CA3093731A1 (fr) | 2019-09-26 |
US20190290775A1 (en) | 2019-09-26 |
US20230110128A1 (en) | 2023-04-13 |
AU2019240403A1 (en) | 2020-10-08 |
CN112189020A (zh) | 2021-01-05 |
TW202003047A (zh) | 2020-01-16 |
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