SG11202009264WA - Use of antibody drug conjugates comprising tubulin disrupting agents to treat solid tumor - Google Patents
Use of antibody drug conjugates comprising tubulin disrupting agents to treat solid tumorInfo
- Publication number
- SG11202009264WA SG11202009264WA SG11202009264WA SG11202009264WA SG11202009264WA SG 11202009264W A SG11202009264W A SG 11202009264WA SG 11202009264W A SG11202009264W A SG 11202009264WA SG 11202009264W A SG11202009264W A SG 11202009264WA SG 11202009264W A SG11202009264W A SG 11202009264WA
- Authority
- SG
- Singapore
- Prior art keywords
- solid tumor
- drug conjugates
- antibody drug
- disrupting agents
- treat solid
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/6805—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a vinca alkaloid
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- A61K47/6889—Conjugates wherein the antibody being the modifying agent and wherein the linker, binder or spacer confers particular properties to the conjugates, e.g. peptidic enzyme-labile linkers or acid-labile linkers, providing for an acid-labile immuno conjugate wherein the drug may be released from its antibody conjugated part in an acidic, e.g. tumoural or environment
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Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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US201862647346P | 2018-03-23 | 2018-03-23 | |
US201862658276P | 2018-04-16 | 2018-04-16 | |
PCT/US2019/023516 WO2019183438A1 (fr) | 2018-03-23 | 2019-03-22 | Utilisation de conjugués anticorps-médicament comprenant des agents de rupture de tubuline pour traiter une tumeur solide |
Publications (1)
Publication Number | Publication Date |
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SG11202009264WA true SG11202009264WA (en) | 2020-10-29 |
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SG11202009264WA SG11202009264WA (en) | 2018-03-23 | 2019-03-22 | Use of antibody drug conjugates comprising tubulin disrupting agents to treat solid tumor |
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US (2) | US20190290775A1 (fr) |
EP (1) | EP3768714A1 (fr) |
JP (1) | JP2021518397A (fr) |
KR (1) | KR20200135841A (fr) |
CN (1) | CN112189020A (fr) |
AU (1) | AU2019240403A1 (fr) |
BR (1) | BR112020018948A2 (fr) |
CA (1) | CA3093731A1 (fr) |
IL (1) | IL277338A (fr) |
MA (1) | MA52135A (fr) |
MX (1) | MX2020009842A (fr) |
SG (1) | SG11202009264WA (fr) |
TW (1) | TW202003047A (fr) |
WO (1) | WO2019183438A1 (fr) |
Families Citing this family (4)
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JP2023523372A (ja) * | 2020-05-03 | 2023-06-02 | シャンハイ ミラコーケン インコーポレイティド | 抗体-薬物コンジュゲート及びその調製物 |
MX2022016232A (es) * | 2020-06-19 | 2023-03-14 | Agensys Inc | Marcadores para uso en metodos para tratar canceres con conjugados de anticuerpo y farmaco (adc). |
EP4217395A1 (fr) * | 2020-09-28 | 2023-08-02 | Seagen Inc. | Anticorps anti-liv1 humanisés destinés au traitement du cancer |
AU2022377628A1 (en) | 2021-10-29 | 2024-04-11 | Seagen Inc. | Methods of treating cancer with a combination of an anti-pd-1 antibody and an anti-cd30 antibody-drug conjugate |
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-
2019
- 2019-03-22 MA MA052135A patent/MA52135A/fr unknown
- 2019-03-22 KR KR1020207030320A patent/KR20200135841A/ko active Search and Examination
- 2019-03-22 EP EP19715720.9A patent/EP3768714A1/fr active Pending
- 2019-03-22 US US16/362,125 patent/US20190290775A1/en not_active Abandoned
- 2019-03-22 CN CN201980033040.7A patent/CN112189020A/zh active Pending
- 2019-03-22 CA CA3093731A patent/CA3093731A1/fr active Pending
- 2019-03-22 JP JP2020550674A patent/JP2021518397A/ja active Pending
- 2019-03-22 AU AU2019240403A patent/AU2019240403A1/en active Pending
- 2019-03-22 SG SG11202009264WA patent/SG11202009264WA/en unknown
- 2019-03-22 TW TW108109929A patent/TW202003047A/zh unknown
- 2019-03-22 WO PCT/US2019/023516 patent/WO2019183438A1/fr active Application Filing
- 2019-03-22 BR BR112020018948-0A patent/BR112020018948A2/pt not_active Application Discontinuation
- 2019-03-22 MX MX2020009842A patent/MX2020009842A/es unknown
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2020
- 2020-09-14 IL IL277338A patent/IL277338A/en unknown
-
2022
- 2022-07-21 US US17/870,749 patent/US20230110128A1/en active Pending
Also Published As
Publication number | Publication date |
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JP2021518397A (ja) | 2021-08-02 |
IL277338A (en) | 2020-10-29 |
EP3768714A1 (fr) | 2021-01-27 |
US20230110128A1 (en) | 2023-04-13 |
TW202003047A (zh) | 2020-01-16 |
CA3093731A1 (fr) | 2019-09-26 |
WO2019183438A1 (fr) | 2019-09-26 |
BR112020018948A2 (pt) | 2021-01-05 |
MA52135A (fr) | 2021-01-27 |
CN112189020A (zh) | 2021-01-05 |
MX2020009842A (es) | 2020-10-15 |
KR20200135841A (ko) | 2020-12-03 |
AU2019240403A1 (en) | 2020-10-08 |
US20190290775A1 (en) | 2019-09-26 |
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