HUE027657T2 - New STAT3 pathway inhibitors and cancer stem cell inhibitors - Google Patents

New STAT3 pathway inhibitors and cancer stem cell inhibitors Download PDF

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Publication number
HUE027657T2
HUE027657T2 HUE08830471A HUE08830471A HUE027657T2 HU E027657 T2 HUE027657 T2 HU E027657T2 HU E08830471 A HUE08830471 A HU E08830471A HU E08830471 A HUE08830471 A HU E08830471A HU E027657 T2 HUE027657 T2 HU E027657T2
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substituted
cancer
aryl
alkyl
cycloalkyl
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HUE08830471A
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Hungarian (hu)
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Zhiwei Jiang
Chiang Jia Li
Wei Li
David Leggett
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Boston Biomedical Inc
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Publication of HUE027657T2 publication Critical patent/HUE027657T2/en

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    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/92Naphthofurans; Hydrogenated naphthofurans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • AHUMAN NECESSITIES
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    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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    • A61P35/00Antineoplastic agents
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/74Naphthothiophenes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Animal Behavior & Ethology (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Immunology (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
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  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Heart & Thoracic Surgery (AREA)
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  • Biophysics (AREA)
  • Inorganic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Communicable Diseases (AREA)
  • Hospice & Palliative Care (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Transplantation (AREA)
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HUE08830471A 2007-09-10 2008-09-10 New STAT3 pathway inhibitors and cancer stem cell inhibitors HUE027657T2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US97114407P 2007-09-10 2007-09-10
US1337207P 2007-12-13 2007-12-13

Publications (1)

Publication Number Publication Date
HUE027657T2 true HUE027657T2 (en) 2016-11-28

Family

ID=40452461

Family Applications (3)

Application Number Title Priority Date Filing Date
HUE08830471A HUE027657T2 (en) 2007-09-10 2008-09-10 New STAT3 pathway inhibitors and cancer stem cell inhibitors
HUE08830633A HUE029111T2 (en) 2007-09-10 2008-09-10 New treatments and methods for treating cancer
HUE08830619A HUE027443T2 (en) 2007-09-10 2008-09-10 A novel class of Stat3 pathway inhibitors and tumor stem cell inhibitors

Family Applications After (2)

Application Number Title Priority Date Filing Date
HUE08830633A HUE029111T2 (en) 2007-09-10 2008-09-10 New treatments and methods for treating cancer
HUE08830619A HUE027443T2 (en) 2007-09-10 2008-09-10 A novel class of Stat3 pathway inhibitors and tumor stem cell inhibitors

Country Status (14)

Country Link
US (12) US8877803B2 (OSRAM)
EP (6) EP3058941B1 (OSRAM)
JP (16) JP5688840B2 (OSRAM)
CN (6) CN101854930B (OSRAM)
CA (4) CA2736563C (OSRAM)
CY (3) CY1117604T1 (OSRAM)
DK (4) DK2194987T3 (OSRAM)
ES (3) ES2583010T3 (OSRAM)
HR (3) HRP20160625T1 (OSRAM)
HU (3) HUE027657T2 (OSRAM)
PL (4) PL3067054T3 (OSRAM)
PT (2) PT2200431T (OSRAM)
SI (3) SI2194987T1 (OSRAM)
WO (3) WO2009036059A2 (OSRAM)

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