HUE024962T2 - Antibodies against Clostridium difficile toxins and uses thereof - Google Patents
Antibodies against Clostridium difficile toxins and uses thereof Download PDFInfo
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- HUE024962T2 HUE024962T2 HUE10010733A HUE10010733A HUE024962T2 HU E024962 T2 HUE024962 T2 HU E024962T2 HU E10010733 A HUE10010733 A HU E10010733A HU E10010733 A HUE10010733 A HU E10010733A HU E024962 T2 HUE024962 T2 HU E024962T2
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Classifications
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- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/565—Complementarity determining region [CDR]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
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- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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- G—PHYSICS
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- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/33—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Clostridium (G)
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
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Landscapes
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| US54235704P | 2004-02-06 | 2004-02-06 | |
| US61385404P | 2004-09-28 | 2004-09-28 |
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| HUE024962T2 true HUE024962T2 (en) | 2016-02-29 |
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| HUE10010733A HUE024962T2 (en) | 2004-02-06 | 2005-02-04 | Antibodies against Clostridium difficile toxins and uses thereof |
| HUE14194551A HUE034552T2 (en) | 2004-02-06 | 2005-02-04 | Antibodies against Clostridium difficile toxins and uses thereof |
| HUS1700028C HUS1700028I1 (hu) | 2004-02-06 | 2017-06-27 | Antitestek a Clostridium difficile toxinok ellen és azok felhasználásai |
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| HUE14194551A HUE034552T2 (en) | 2004-02-06 | 2005-02-04 | Antibodies against Clostridium difficile toxins and uses thereof |
| HUS1700028C HUS1700028I1 (hu) | 2004-02-06 | 2017-06-27 | Antitestek a Clostridium difficile toxinok ellen és azok felhasználásai |
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| EP (3) | EP2857418B1 (OSRAM) |
| JP (3) | JP4588763B2 (OSRAM) |
| KR (3) | KR101332994B1 (OSRAM) |
| CN (1) | CN101014620B (OSRAM) |
| AT (1) | ATE512986T1 (OSRAM) |
| AU (1) | AU2005320349C1 (OSRAM) |
| BE (1) | BE2017C023I2 (OSRAM) |
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| AR045563A1 (es) | 2003-09-10 | 2005-11-02 | Warner Lambert Co | Anticuerpos dirigidos a m-csf |
| DK1766093T3 (da) | 2004-02-06 | 2011-10-03 | Univ Massachusetts | Antistoffer mod clostridium difficile-toksiner og anvendelse deraf |
| US9103820B2 (en) * | 2004-06-28 | 2015-08-11 | Japan Science And Technology Agency | Method for screening toxin neutralizing peptide, STX2 inhibiting peptide and verotoxin neutralizing agent |
| EP1833510A4 (en) * | 2004-12-27 | 2010-02-10 | Progenics Pharmaceuticals Neva | ORAL ADMINISTRATION ANTITOXIN ANTIBODIES AND METHODS OF MAKING AND USING THE SAME |
| US20090311258A1 (en) | 2006-08-02 | 2009-12-17 | Johannes Gutenberg-Universitaet Mainz | Medicament for lct poisoning |
| CA3034396C (en) | 2007-01-30 | 2022-08-02 | Epivax, Inc. | Regulatory t cell epitopes, compositions and uses thereof |
| AU2014201846B2 (en) * | 2007-01-30 | 2016-07-07 | Epivax, Inc. | Regulatory t cell epitopes, compositions and uses thereof |
| US20080188007A1 (en) * | 2007-02-06 | 2008-08-07 | Meridian Life Science, Inc. | Fluorescent single chain antibody and its use in detection of analytes |
| CN101363867B (zh) * | 2008-05-26 | 2012-12-19 | 北京庄笛浩禾生物医学科技有限公司 | 一种艰难梭菌a、b毒素胶体金检测试纸条及其制备方法 |
| WO2009154995A2 (en) * | 2008-05-27 | 2009-12-23 | Kyowa Hakko Kirin Co., Ltd. | Interleukin 10 receptor (il-10r) antibodies and methods of use |
| DE102008029688B4 (de) * | 2008-06-24 | 2016-06-23 | Biodics Gmbh | Verfahren zum Nachweis und zur Identifikation eines varianten C. difficile Stammes in einer Probe |
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