CH593992A5
(da)
*
|
1972-12-23 |
1977-12-30 |
Roehm Gmbh |
|
GB1550819A
(en)
*
|
1975-06-04 |
1979-08-22 |
Nat Res Dev |
Polymeric support for biogically active materials
|
JPS5272284A
(en)
*
|
1975-12-12 |
1977-06-16 |
Dainippon Pharmaceutical Co |
Enzymeeimmunoassay reagent
|
US4108804A
(en)
*
|
1975-12-23 |
1978-08-22 |
Toru Seita |
Process for preparation of chromatography solid supports comprising a nucleic acid base-epoxy group containing porous gel
|
US4046723A
(en)
*
|
1976-04-22 |
1977-09-06 |
The Dow Chemical Company |
Azide bonding of a protein to a latex
|
US4179423A
(en)
*
|
1976-06-09 |
1979-12-18 |
Schenectady Chemicals, Inc. |
Water-soluble polyester imide resins
|
US4206261A
(en)
*
|
1976-06-09 |
1980-06-03 |
Schenectady Chemicals, Inc. |
Water-soluble polyester imide resin wire coating process
|
US4045384A
(en)
*
|
1976-07-23 |
1977-08-30 |
The Dow Chemical Company |
Method for forming an amide bond between a latex and protein
|
DE2708018A1
(de)
*
|
1977-02-24 |
1978-09-07 |
Boehringer Mannheim Gmbh |
An polyamid fixiertes biologisch aktives protein und verfahren zu seiner herstellung
|
US4275000A
(en)
*
|
1977-08-22 |
1981-06-23 |
National Research Development Corporation |
Peptide macromolecular complexes
|
US4206286A
(en)
*
|
1977-11-14 |
1980-06-03 |
Technicon Instruments Corporation |
Immobilization of proteins on inorganic supports
|
US4338398A
(en)
*
|
1979-03-20 |
1982-07-06 |
Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo |
Immobilization of starch degrading enzymes
|
US4415665A
(en)
*
|
1980-12-12 |
1983-11-15 |
Pharmacia Fine Chemicals Ab |
Method of covalently binding biologically active organic substances to polymeric substances
|
DE3126551C2
(de)
*
|
1981-07-04 |
1983-12-15 |
Rolf Dr. 8700 Würzburg Siegel |
Herstellungsverfahren für Materialien zur Immobilisierung von Proteinen und Kohlenhydratgruppen
|
US4506019A
(en)
*
|
1982-09-24 |
1985-03-19 |
Leeco Diagnostics, Inc. |
Activated polymer container means and assay method employing the same
|
US4596777A
(en)
*
|
1983-08-10 |
1986-06-24 |
E. R. Squibb & Sons, Inc. |
Process for preparing (3S)-3-[[[2-(protected or unprotected amino)-4-thiazolyl]acetyl]amino]-2-oxo-1-azetidinesulfonic acid and 4-substituted derivatives thereof
|
US4711840A
(en)
*
|
1984-01-27 |
1987-12-08 |
Genetic Systems Corporation |
Polymerization-induced separation immunoassays
|
US4609707A
(en)
*
|
1983-11-10 |
1986-09-02 |
Genetic Systems Corporation |
Synthesis of polymers containing integral antibodies
|
US4511478A
(en)
*
|
1983-11-10 |
1985-04-16 |
Genetic Systems Corporation |
Polymerizable compounds and methods for preparing synthetic polymers that integrally contain polypeptides
|
US4752638A
(en)
*
|
1983-11-10 |
1988-06-21 |
Genetic Systems Corporation |
Synthesis and use of polymers containing integral binding-pair members
|
US4843010A
(en)
*
|
1983-11-10 |
1989-06-27 |
Genetic Systems Corporation |
Polymerization-induced separation immunoassays
|
MC1637A1
(fr)
*
|
1983-11-10 |
1986-01-09 |
Genetic Systems Corp |
Composes polymerisables contenant des polypeptides comme partie integrante et leur utilisation dans des epreuves immunologiques de separation induite par polymerisation
|
JPH0820447B2
(ja)
*
|
1984-01-27 |
1996-03-04 |
ジェネティック システムズ コーポレーション |
液体混合物から物質を分離する方法及び免疫評価法
|
US4695624A
(en)
*
|
1984-05-10 |
1987-09-22 |
Merck & Co., Inc. |
Covalently-modified polyanionic bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins with bigeneric spacers, and methods of preparing such polysaccharides and conjugates and of confirming covalency
|
US4749647A
(en)
*
|
1984-06-22 |
1988-06-07 |
Genetic Systems Corporation |
Polymerization-induced separation assay using recognition pairs
|
EP0257758B1
(en)
*
|
1986-08-07 |
1993-03-10 |
Minnesota Mining And Manufacturing Company |
Stable biologically active fluorochemical emulsions
|
US4808530A
(en)
*
|
1986-09-05 |
1989-02-28 |
The Ohio State University |
Protein immobilization by adsorption of a hydrophobic amidine protein derivative to a hydrophobic surface
|
US4885250A
(en)
*
|
1987-03-02 |
1989-12-05 |
E. I. Du Pont De Nemours And Company |
Enzyme immobilization and bioaffinity separations with perfluorocarbon polymer-based supports
|
US5063109A
(en)
*
|
1988-10-11 |
1991-11-05 |
Abbott Laboratories |
Covalent attachment of antibodies and antigens to solid phases using extended length heterobifunctional coupling agents
|
US5116964A
(en)
|
1989-02-23 |
1992-05-26 |
Genentech, Inc. |
Hybrid immunoglobulins
|
ES2084069T3
(es)
*
|
1990-08-15 |
1996-05-01 |
Abbott Lab |
Reactivos de inmunoensayo y metodo para la determinacion de ciclosporina.
|
US5612034A
(en)
*
|
1990-10-03 |
1997-03-18 |
Redcell, Inc. |
Super-globuling for in vivo extended lifetimes
|
US5482996A
(en)
*
|
1993-12-08 |
1996-01-09 |
University Of Pittsburgh |
Protein-containing polymers and a method of synthesis of protein-containing polymers in organic solvents
|
US6057287A
(en)
|
1994-01-11 |
2000-05-02 |
Dyax Corp. |
Kallikrein-binding "Kunitz domain" proteins and analogues thereof
|
PT739355E
(pt)
*
|
1994-01-11 |
2005-01-31 |
Dyax Corp |
Proteinas de 'dominio de kunitz' inibidoras de calicreina e seus analogos
|
US6045797A
(en)
*
|
1994-03-14 |
2000-04-04 |
New York University Medical Center |
Treatment or diagnosis of diseases or conditions associated with a BLM domain
|
US5877016A
(en)
|
1994-03-18 |
1999-03-02 |
Genentech, Inc. |
Human trk receptors and neurotrophic factor inhibitors
|
US5708142A
(en)
|
1994-05-27 |
1998-01-13 |
Genentech, Inc. |
Tumor necrosis factor receptor-associated factors
|
US5736624A
(en)
*
|
1994-12-02 |
1998-04-07 |
Abbott Laboratories |
Phosphatase activated crosslinking, conjugating and reducing agents; methods of using such agents; and reagents comprising phosphatase activated crosslinking and conjugating agents
|
US5837815A
(en)
*
|
1994-12-15 |
1998-11-17 |
Sugen, Inc. |
PYK2 related polypeptide products
|
US5837524A
(en)
*
|
1994-12-15 |
1998-11-17 |
Sugen, Inc. |
PYK2 related polynucleotide products
|
US5807989A
(en)
*
|
1994-12-23 |
1998-09-15 |
New York University |
Methods for treatment or diagnosis of diseases or disorders associated with an APB domain
|
US6300482B1
(en)
|
1995-01-03 |
2001-10-09 |
Max-Flanck-Gesellschaft Zuer For{Overscore (D)}Erung Der |
MDKI, a novel receptor tyrosine kinase
|
US6565842B1
(en)
*
|
1995-06-07 |
2003-05-20 |
American Bioscience, Inc. |
Crosslinkable polypeptide compositions
|
US7005505B1
(en)
|
1995-08-25 |
2006-02-28 |
Genentech, Inc. |
Variants of vascular endothelial cell growth factor
|
US6020473A
(en)
*
|
1995-08-25 |
2000-02-01 |
Genentech, Inc. |
Nucleic acids encoding variants of vascular endothelial cell growth factor
|
CA2231850A1
(en)
|
1995-09-15 |
1997-03-20 |
Sergio Onate |
Steroid receptor coactivator compositions and methods of use
|
US6046048A
(en)
*
|
1996-01-09 |
2000-04-04 |
Genetech, Inc. |
Apo-2 ligand
|
US20050089958A1
(en)
*
|
1996-01-09 |
2005-04-28 |
Genentech, Inc. |
Apo-2 ligand
|
US6998116B1
(en)
*
|
1996-01-09 |
2006-02-14 |
Genentech, Inc. |
Apo-2 ligand
|
US6030945A
(en)
*
|
1996-01-09 |
2000-02-29 |
Genentech, Inc. |
Apo-2 ligand
|
US20020165157A1
(en)
*
|
1996-04-01 |
2002-11-07 |
Genentech, Inc. |
Apo-2LI and Apo-3 polypeptides
|
CA2249206A1
(en)
|
1996-04-01 |
1997-10-09 |
Genentech, Inc. |
Apo-2li and apo-3 apoptosis polypeptides
|
US6100071A
(en)
|
1996-05-07 |
2000-08-08 |
Genentech, Inc. |
Receptors as novel inhibitors of vascular endothelial growth factor activity and processes for their production
|
US5851984A
(en)
*
|
1996-08-16 |
1998-12-22 |
Genentech, Inc. |
Method of enhancing proliferation or differentiation of hematopoietic stem cells using Wnt polypeptides
|
US6159462A
(en)
*
|
1996-08-16 |
2000-12-12 |
Genentech, Inc. |
Uses of Wnt polypeptides
|
US6462176B1
(en)
|
1996-09-23 |
2002-10-08 |
Genentech, Inc. |
Apo-3 polypeptide
|
DK0942992T3
(da)
|
1997-01-31 |
2007-07-02 |
Genentech Inc |
O-fucosyltransferase
|
US20040241645A1
(en)
*
|
1997-01-31 |
2004-12-02 |
Genentech, Inc. |
O-fucosyltransferase
|
US20020102706A1
(en)
*
|
1997-06-18 |
2002-08-01 |
Genentech, Inc. |
Apo-2DcR
|
US20100152426A1
(en)
*
|
1997-05-15 |
2010-06-17 |
Ashkenazi Avi J |
Apo-2 receptor fusion proteins
|
ES2293682T5
(es)
|
1997-05-15 |
2011-11-17 |
Genentech, Inc. |
Anticuerpo anti-apo2.
|
US6342369B1
(en)
*
|
1997-05-15 |
2002-01-29 |
Genentech, Inc. |
Apo-2-receptor
|
WO1998055615A1
(en)
|
1997-06-05 |
1998-12-10 |
The University Of Texas Board Or Regents |
Apaf-1, the ced-4 human homolog, an activator of caspase-3
|
JP2002508663A
(ja)
*
|
1997-06-18 |
2002-03-19 |
ジェネンテク,インコーポレイテッド |
Apo−2DcR
|
US6506550B1
(en)
|
1997-07-11 |
2003-01-14 |
Brandeis University |
Method of including apoptosis by reducing the level of thiamin
|
US20030175856A1
(en)
*
|
1997-08-26 |
2003-09-18 |
Genetech, Inc. |
Rtd receptor
|
ES2331900T3
(es)
*
|
1997-08-26 |
2010-01-19 |
Genentech, Inc. |
Receptor rtd.
|
US8679534B2
(en)
*
|
1997-12-12 |
2014-03-25 |
Andrx Labs, Llc |
HMG-CoA reductase inhibitor extended release formulation
|
AU2325199A
(en)
|
1998-01-15 |
1999-08-02 |
Genentech Inc. |
Apo-2 ligand
|
DE69941453D1
(de)
*
|
1998-06-12 |
2009-11-05 |
Genentech Inc |
Monoklonale antikörper, kreuz-reaktive antikörper und deren produktionsverfahren
|
US6984719B1
(en)
|
1998-09-17 |
2006-01-10 |
Hospital Sainte-Justine |
Peptide antagonists of prostaglandin F2α receptor
|
US6368793B1
(en)
|
1998-10-14 |
2002-04-09 |
Microgenomics, Inc. |
Metabolic selection methods
|
AU773891C
(en)
|
1998-10-23 |
2005-02-17 |
Kirin-Amgen Inc. |
Dimeric thrombopoietin peptide mimetics binding to MP1 receptor and having thrombopoietic activity
|
US6660843B1
(en)
*
|
1998-10-23 |
2003-12-09 |
Amgen Inc. |
Modified peptides as therapeutic agents
|
US6982153B1
(en)
|
1998-12-03 |
2006-01-03 |
Targanta Therapeutics, Inc. |
DNA sequences from staphylococcus aureus bacteriophage 77 that encode anti-microbial polypeptides
|
US6861442B1
(en)
*
|
1998-12-30 |
2005-03-01 |
Sugen, Inc. |
PYK2 and inflammation
|
JP2003502033A
(ja)
|
1999-06-16 |
2003-01-21 |
アイコス コーポレイション |
ヒトポリ(adp−リボース)ポリアミラーゼ2材料および方法
|
US20040235749A1
(en)
*
|
1999-09-15 |
2004-11-25 |
Sylvain Chemtob |
G-protein coupled receptor antagonists
|
US20030138771A1
(en)
*
|
1999-09-30 |
2003-07-24 |
Jerry Pelletier |
DNA sequences from S. pneumoniae bacteriophage DP1 that encode anti-microbal polypeptides
|
US6808902B1
(en)
|
1999-11-12 |
2004-10-26 |
Amgen Inc. |
Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
|
WO2001036972A2
(en)
|
1999-11-16 |
2001-05-25 |
Genentech, Inc. |
Elisa for vegf
|
DE60117781T2
(de)
|
2000-04-21 |
2006-11-23 |
Amgen Inc., Thousand Oaks |
Peptidderivate des apolipoproteins-a1/aii
|
US6667300B2
(en)
|
2000-04-25 |
2003-12-23 |
Icos Corporation |
Inhibitors of human phosphatidylinositol 3-kinase delta
|
US6677136B2
(en)
|
2000-05-03 |
2004-01-13 |
Amgen Inc. |
Glucagon antagonists
|
US6911204B2
(en)
|
2000-08-11 |
2005-06-28 |
Favrille, Inc. |
Method and composition for altering a B cell mediated pathology
|
US20030012782A1
(en)
*
|
2000-08-11 |
2003-01-16 |
Gold Daniel P. |
Method and composition for altering a T cell mediated pathology
|
EA010435B1
(ru)
|
2001-05-11 |
2008-08-29 |
Амген, Инк. |
Связывающиеся с tall-1 молекулы и их применение
|
EP2292271A3
(en)
|
2001-10-10 |
2011-09-14 |
BioGeneriX AG |
Remodelling and glycoconjugation of an antibody
|
ZA200700168B
(en)
|
2001-10-10 |
2010-02-24 |
Novo Nordisk As |
Remodeling and glycoconjugation of peptides
|
US7138370B2
(en)
|
2001-10-11 |
2006-11-21 |
Amgen Inc. |
Specific binding agents of human angiopoietin-2
|
US7332474B2
(en)
*
|
2001-10-11 |
2008-02-19 |
Amgen Inc. |
Peptides and related compounds having thrombopoietic activity
|
US20040054082A1
(en)
*
|
2001-12-03 |
2004-03-18 |
Bank David H |
Toughened polymer blends with improved surface properties
|
US20100311954A1
(en)
*
|
2002-03-01 |
2010-12-09 |
Xencor, Inc. |
Optimized Proteins that Target Ep-CAM
|
US7153829B2
(en)
*
|
2002-06-07 |
2006-12-26 |
Dyax Corp. |
Kallikrein-inhibitor therapies
|
ATE477020T1
(de)
|
2002-06-07 |
2010-08-15 |
Dyax Corp |
Prevention und verringerung von ischemia
|
US7521530B2
(en)
|
2002-06-11 |
2009-04-21 |
Universite De Montreal |
Peptides and peptidomimetics useful for inhibiting the activity of prostaglandin F2α receptor
|
JP2005537006A
(ja)
*
|
2002-08-28 |
2005-12-08 |
ダイアックス、コープ |
臓器及び組織の保存方法
|
US6919426B2
(en)
|
2002-09-19 |
2005-07-19 |
Amgen Inc. |
Peptides and related molecules that modulate nerve growth factor activity
|
SG155777A1
(en)
|
2003-04-09 |
2009-10-29 |
Neose Technologies Inc |
Glycopegylation methods and proteins/peptides produced by the methods
|
US20050043239A1
(en)
*
|
2003-08-14 |
2005-02-24 |
Jason Douangpanya |
Methods of inhibiting immune responses stimulated by an endogenous factor
|
WO2005016349A1
(en)
*
|
2003-08-14 |
2005-02-24 |
Icos Corporation |
Methods of inhibiting leukocyte accumulation
|
US8399618B2
(en)
|
2004-10-21 |
2013-03-19 |
Xencor, Inc. |
Immunoglobulin insertions, deletions, and substitutions
|
US20060134105A1
(en)
*
|
2004-10-21 |
2006-06-22 |
Xencor, Inc. |
IgG immunoglobulin variants with optimized effector function
|
US8883147B2
(en)
|
2004-10-21 |
2014-11-11 |
Xencor, Inc. |
Immunoglobulins insertions, deletions, and substitutions
|
EP1682109B1
(en)
*
|
2003-10-22 |
2008-10-15 |
Merz Pharma GmbH & Co. KGaA |
The use of 1-aminocyclohexane derivatives to modify deposition of fibrillogenic as peptides in amyloidopathies
|
DE602005027673D1
(de)
*
|
2004-03-05 |
2011-06-09 |
Vegenics Pty Ltd |
Materialien und verfahren für wachstumsfaktorbindende konstrukte
|
ZA200608572B
(en)
*
|
2004-04-16 |
2008-06-25 |
Genentech Inc |
Assay for antibodies
|
RS55551B1
(sr)
*
|
2004-05-13 |
2017-05-31 |
Icos Corp |
Hinazolinoni kao inhibitori humane fosfatidilinozitol 3-kinaze delta
|
JP2007538258A
(ja)
*
|
2004-05-15 |
2007-12-27 |
ジェネンテック・インコーポレーテッド |
標的分子に結合親和性を有する分子を検出するためのクロススクリーニングシステムと方法
|
EP1755609A1
(en)
*
|
2004-05-25 |
2007-02-28 |
Icos Corporation |
Methods for treating and/or preventing aberrant proliferation of hematopoietic cells
|
WO2006010057A2
(en)
*
|
2004-07-08 |
2006-01-26 |
Amgen Inc. |
Therapeutic peptides
|
SI1797127T1
(sl)
*
|
2004-09-24 |
2017-09-29 |
Amgen Inc. |
Modificirane fc-molekule
|
US7235530B2
(en)
|
2004-09-27 |
2007-06-26 |
Dyax Corporation |
Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
|
EP2845865A1
(en)
|
2004-11-12 |
2015-03-11 |
Xencor Inc. |
Fc variants with altered binding to FcRn
|
US8802820B2
(en)
|
2004-11-12 |
2014-08-12 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
EP2290087A3
(en)
|
2004-12-22 |
2011-06-15 |
Genentech, Inc. |
Methods for producing soluble multi-membrane-spanning proteins
|
WO2006089106A2
(en)
*
|
2005-02-17 |
2006-08-24 |
Icos Corporation |
Phosphoinositide 3-kinase inhibitors for inhibiting leukocyte accumulation
|
CA2652434A1
(en)
|
2005-07-08 |
2007-01-18 |
Xencor, Inc. |
Optimized proteins that target ep-cam
|
US8008453B2
(en)
|
2005-08-12 |
2011-08-30 |
Amgen Inc. |
Modified Fc molecules
|
WO2007056411A2
(en)
*
|
2005-11-08 |
2007-05-18 |
Genentech, Inc. |
Method of producing pan-specific antibodies
|
AR056806A1
(es)
|
2005-11-14 |
2007-10-24 |
Amgen Inc |
Moleculas quimericas de anticuerpo rankl- pth/ pthrp
|
US7276480B1
(en)
|
2005-12-30 |
2007-10-02 |
Dyax Corp. |
Prevention and reduction of blood loss
|
WO2007102946A2
(en)
|
2006-01-23 |
2007-09-13 |
Amgen Inc. |
Crystalline polypeptides
|
CA2643693A1
(en)
*
|
2006-03-10 |
2007-09-20 |
Dyax Corp. |
Formulations for ecallantide
|
US9283260B2
(en)
|
2006-04-21 |
2016-03-15 |
Amgen Inc. |
Lyophilized therapeutic peptibody formulations
|
US7981425B2
(en)
*
|
2006-06-19 |
2011-07-19 |
Amgen Inc. |
Thrombopoietic compounds
|
CA2787343C
(en)
|
2006-06-26 |
2016-08-02 |
Amgen Inc. |
Compositions comprising modified lcat and uses thereof
|
WO2009019531A2
(en)
|
2006-09-18 |
2009-02-12 |
Compugen Ltd |
Bioactive peptides and method of using same
|
US7767206B2
(en)
|
2006-10-02 |
2010-08-03 |
Amgen Inc. |
Neutralizing determinants of IL-17 Receptor A and antibodies that bind thereto
|
KR101551984B1
(ko)
|
2006-10-04 |
2015-09-09 |
제넨테크, 인크. |
Vegf용 elisa
|
WO2008051383A2
(en)
*
|
2006-10-19 |
2008-05-02 |
Amgen Inc. |
Use of alcohol co-solvents to improve pegylation reaction yields
|
PE20081140A1
(es)
|
2006-10-25 |
2008-09-22 |
Amgen Inc |
Agentes terapeuticos a base de peptidos derivados de toxinas
|
US20080171344A1
(en)
*
|
2006-12-22 |
2008-07-17 |
Kapsner Kenneth P |
Methods, Kits and Materials for Diagnosing Disease States by Measuring Isoforms or Proforms of Myeloperoxidase
|
CA2687141C
(en)
|
2007-05-22 |
2014-04-01 |
Amgen Inc. |
Compositions and methods for producing bioactive fusion proteins
|
US8492329B2
(en)
|
2007-07-12 |
2013-07-23 |
Compugen Ltd. |
Bioactive peptides and methods of using same
|
DK2489731T3
(da)
|
2007-07-26 |
2014-11-17 |
Amgen Inc |
Modificerede lecithin-kolesterol-acyltransferase-enzymer
|
WO2009029716A1
(en)
|
2007-08-28 |
2009-03-05 |
Ramot At Tel Aviv University |
Peptides inducing a cd4i conformation in hiv gp120 while retaining vacant cd4 binding site
|
HUE024903T2
(en)
|
2007-12-26 |
2016-02-29 |
Xencor Inc |
FC variants with modified binding to FCRN
|
WO2010027802A2
(en)
*
|
2008-08-25 |
2010-03-11 |
New York University |
Methods for treating diabetic wounds
|
US20100202963A1
(en)
|
2008-11-13 |
2010-08-12 |
Gallatin W Michael |
Therapies for hematologic malignancies
|
US9492449B2
(en)
|
2008-11-13 |
2016-11-15 |
Gilead Calistoga Llc |
Therapies for hematologic malignancies
|
EP2385843A4
(en)
*
|
2009-01-06 |
2013-02-27 |
Dyax Corp |
TREATMENT OF MUZOSITIS WITH CALLICINE INHIBITORS
|
AU2010229968A1
(en)
|
2009-03-24 |
2011-10-13 |
Gilead Calistoga Llc |
Atropisomers of2-purinyl-3-tolyl-quinazolinone derivatives and methods of use
|
ES2548253T3
(es)
*
|
2009-04-20 |
2015-10-15 |
Gilead Calistoga Llc |
Métodos para el tratamiento de tumores sólidos
|
BR112012001325A2
(pt)
|
2009-07-21 |
2017-05-02 |
Gilead Calistoga Llc |
tratamento de distúrbios do fígado com inibidaores de pi3k
|
TW201117824A
(en)
|
2009-10-12 |
2011-06-01 |
Amgen Inc |
Use of IL-17 receptor a antigen binding proteins
|
WO2011049625A1
(en)
|
2009-10-20 |
2011-04-28 |
Mansour Samadpour |
Method for aflatoxin screening of products
|
CN102695956B
(zh)
*
|
2009-10-26 |
2015-12-09 |
基因泰克公司 |
用于检测对治疗性抗IgE抗体特异性的抗体的测定法及其在过敏反应中的用途
|
KR102012398B1
(ko)
|
2009-11-05 |
2019-08-20 |
리젠 파마슈티컬스 소시에떼 아노님 |
신규한 벤조피란 키나제 조절제
|
CA3168591A1
(en)
|
2010-01-06 |
2011-07-14 |
Takeda Pharmaceutical Company Limited |
Plasma kallikrein binding proteins
|
WO2011097527A2
(en)
|
2010-02-04 |
2011-08-11 |
Xencor, Inc. |
Immunoprotection of therapeutic moieties using enhanced fc regions
|
US20110189178A1
(en)
*
|
2010-02-04 |
2011-08-04 |
Xencor, Inc. |
Immunoprotection of Therapeutic Moieties Using Enhanced Fc Regions
|
ES2575160T3
(es)
|
2010-03-15 |
2016-06-24 |
The Board Of Trustees Of The University Of Illinois |
Inhibidores de las interacciones que unen la subunidad alfa de la beta integrina-proteína G
|
KR101871436B1
(ko)
|
2010-05-17 |
2018-06-27 |
인코젠 쎄라퓨틱스 프라이빗 리미티드 |
단백질 키나제의 조절제로서의 신규한 3,5-디치환-3h-이미다조[4,5-b]피리딘 및 3,5- 디치환 -3h-[1,2,3]트리아졸로[4,5-b] 피리딘 화합물
|
CA3111806A1
(en)
|
2010-06-17 |
2011-12-22 |
New York University |
Therapeutic and cosmetic uses and applications of calreticulin
|
WO2012030738A2
(en)
|
2010-08-30 |
2012-03-08 |
Beckman Coulter, Inc. |
Complex phosphoprotein activation profiles
|
EP3828205A1
(en)
|
2010-10-01 |
2021-06-02 |
Oxford BioTherapeutics Ltd |
Anti-ror1 antibodies
|
US9029502B2
(en)
|
2010-12-20 |
2015-05-12 |
The Regents Of The University Of Michigan |
Inhibitors of the epidermal growth factor receptor-heat shock protein 90 binding interaction
|
JOP20210044A1
(ar)
|
2010-12-30 |
2017-06-16 |
Takeda Pharmaceuticals Co |
الأجسام المضادة لـ cd38
|
JP2014506257A
(ja)
|
2011-01-06 |
2014-03-13 |
ダイアックス コーポレーション |
血漿カリクレイン結合タンパク質
|
UY33959A
(es)
|
2011-03-16 |
2012-09-28 |
Amgen Inc |
INHIBIDORES POTENTES Y SELECTIVOS DE NaV1.3 Y NaV1.7
|
BR112013027867A2
(pt)
|
2011-04-29 |
2016-09-06 |
Bristol Myers Squibb Co |
"método de detectar o nível de um anticorpo anti-ip10 em amostra, anticorpo monoclonal isolado ou porção de ligação de antígeno do mesmo, linhagem de célula de hibridoma e kit"
|
MX365160B
(es)
|
2011-05-04 |
2019-05-24 |
Rhizen Pharmaceuticals Sa |
Compuestos novedosos como moduladores de proteína cinasas.
|
US20140234330A1
(en)
|
2011-07-22 |
2014-08-21 |
Amgen Inc. |
Il-17 receptor a is required for il-17c biology
|
US8987422B2
(en)
|
2011-09-22 |
2015-03-24 |
Amgen Inc. |
CD27L antigen binding proteins
|
US10851178B2
(en)
|
2011-10-10 |
2020-12-01 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
MX2014010656A
(es)
|
2012-03-05 |
2015-03-03 |
Gilead Calistoga Llc |
Formas polimorficas de (s)-2-(1-(9h-purin-6-ilamino)propil)-5-fluo ro-3-fenilquinazolin-4(3h)-ona.
|
US20150079100A1
(en)
|
2012-03-23 |
2015-03-19 |
Bristol-Myers Squibb Company |
Methods of treatments using ctla-4 antibodies
|
JP2015518471A
(ja)
|
2012-03-28 |
2015-07-02 |
ジェネンテック, インコーポレイテッド |
抗hcmvイディオタイプ抗体およびそれらの使用
|
SG11201406185WA
(en)
|
2012-03-30 |
2014-11-27 |
Rhizen Pharmaceuticals Sa |
Novel 3,5-disubstitued-3h-imidazo[4,5-b]pyridine and 3,5- disubstitued -3h-[1,2,3]triazolo[4,5-b] pyridine compounds as modulators of c-met protein kinases
|
US10385395B2
(en)
|
2012-04-11 |
2019-08-20 |
The Regents Of The University Of California |
Diagnostic tools for response to 6-thiopurine therapy
|
JO3623B1
(ar)
|
2012-05-18 |
2020-08-27 |
Amgen Inc |
البروتينات المرتبطة بمولد المستضاد st2
|
TW201425336A
(zh)
|
2012-12-07 |
2014-07-01 |
Amgen Inc |
Bcma抗原結合蛋白質
|
EP3907237A1
(en)
|
2012-12-20 |
2021-11-10 |
Amgen Inc. |
Apj receptor agonists and uses thereof
|
US9920121B2
(en)
|
2013-01-25 |
2018-03-20 |
Amgen Inc. |
Antibodies targeting CDH19 for melanoma
|
JO3519B1
(ar)
|
2013-01-25 |
2020-07-05 |
Amgen Inc |
تركيبات أجسام مضادة لأجل cdh19 و cd3
|
CA2894644A1
(en)
|
2013-02-06 |
2014-08-14 |
Pieris Ag |
Novel lipocalin-mutein assays for measuring hepcidin concentration
|
AU2014218318B2
(en)
|
2013-02-18 |
2018-02-15 |
Vegenics Pty Limited |
Ligand binding molecules and uses thereof
|
EP2970408B1
(en)
|
2013-03-12 |
2018-01-10 |
Amgen Inc. |
Potent and selective inhibitors of nav1.7
|
US9546203B2
(en)
|
2013-03-14 |
2017-01-17 |
Amgen Inc. |
Aglycosylated Fc-containing polypeptides with cysteine substitutions
|
US9260527B2
(en)
|
2013-03-15 |
2016-02-16 |
Sdix, Llc |
Anti-human CXCR4 antibodies and methods of making same
|
CA2902739C
(en)
|
2013-03-15 |
2022-11-22 |
Xencor, Inc. |
Heterodimeric proteins
|
ES2875853T3
(es)
|
2013-03-15 |
2021-11-11 |
Univ Texas |
Método de tratar fibrosis
|
US9505849B2
(en)
|
2013-03-15 |
2016-11-29 |
Amgen Research (Munich) Gmbh |
Antibody constructs for influenza M2 and CD3
|
CA2906927C
(en)
|
2013-03-15 |
2021-07-13 |
Xencor, Inc. |
Modulation of t cells with bispecific antibodies and fc fusions
|
DK2970449T3
(da)
|
2013-03-15 |
2019-11-25 |
Amgen Res Munich Gmbh |
Enkeltkædede bindingsmolekyler, der omfatter n-terminal abp
|
HUE056580T2
(hu)
|
2013-05-30 |
2022-02-28 |
Kiniksa Pharmaceuticals Ltd |
Onkosztatin-M-receptor antigénjét kötõ fehérjék
|
US20160216262A1
(en)
|
2013-09-12 |
2016-07-28 |
Institut National De La Sante Et De La Recherche Medicale |
Method for In Vitro Quantifying Allo-Antibodies, Auto-Antibodies and/or Therapeutic Antibodies
|
PL3044323T3
(pl)
|
2013-09-13 |
2022-06-27 |
F.Hoffmann-La Roche Ag |
Sposoby wykrywania i ilościowego oznaczania białka komórki gospodarza w liniach komórkowych
|
AR097648A1
(es)
|
2013-09-13 |
2016-04-06 |
Amgen Inc |
Combinación de factores epigenéticos y compuestos biespecíficos que tienen como diana cd33 y cd3 en el tratamiento de leucemia mieloide
|
NZ756750A
(en)
|
2013-09-13 |
2022-05-27 |
Genentech Inc |
Methods and compositions comprising purified recombinant polypeptides
|
CR20160156A
(es)
|
2013-10-11 |
2016-11-01 |
Oxford Biotherapeutics Ltd |
Anticuerpos conjugados contra ly75 para el tratamiento del cáncer
|
AU2014364410B2
(en)
|
2013-12-20 |
2017-11-16 |
Gilead Calistoga Llc |
Process methods for phosphatidylinositol 3-kinase inhibitors
|
EP3083623A1
(en)
|
2013-12-20 |
2016-10-26 |
Gilead Calistoga LLC |
Polymorphic forms of a hydrochloride salt of (s) -2-(9h-purin-6-ylamino) propyl) -5-fluoro-3-phenylquinazolin-4 (3h) -one
|
WO2015106311A1
(en)
|
2014-01-17 |
2015-07-23 |
Minomic International Ltd. |
Cell surface prostate cancer antigen for diagnosis
|
US9701743B2
(en)
|
2014-02-20 |
2017-07-11 |
Allergan, Inc. |
Complement component C5 antibodies
|
KR20160126054A
(ko)
|
2014-02-27 |
2016-11-01 |
알러간, 인코포레이티드 |
보체 인자 Bb 항체
|
KR102555955B1
(ko)
|
2014-03-27 |
2023-07-18 |
다케다 파머수티컬 컴패니 리미티드 |
당뇨병성 황반 부종의 치료를 위한 조성물 및 방법
|
ME03666B
(me)
|
2014-03-28 |
2020-10-20 |
Xencor Inc |
Bispecifična antitela koja se vezuju za cd38 i cd3
|
US10941182B2
(en)
|
2014-06-10 |
2021-03-09 |
Amgen Inc. |
Apelin polypeptides
|
NZ726360A
(en)
|
2014-06-13 |
2018-04-27 |
Gilead Sciences Inc |
Phosphatidylinositol 3-kinase inhibitors
|
AU2015294834B2
(en)
|
2014-07-31 |
2021-04-29 |
Amgen Research (Munich) Gmbh |
Optimized cross-species specific bispecific single chain antibody constructs
|
TW201609811A
(zh)
|
2014-07-31 |
2016-03-16 |
安美基研究(慕尼黑)公司 |
具有增強之組織分布之雙特異性單鏈抗體構築體
|
AR101669A1
(es)
|
2014-07-31 |
2017-01-04 |
Amgen Res (Munich) Gmbh |
Constructos de anticuerpos para cdh19 y cd3
|
WO2016141387A1
(en)
|
2015-03-05 |
2016-09-09 |
Xencor, Inc. |
Modulation of t cells with bispecific antibodies and fc fusions
|
JP6865689B2
(ja)
|
2015-03-06 |
2021-04-28 |
ジェネンテック, インコーポレイテッド |
超精製DsbA及びDsbC、ならびにそれらの作製及び使用方法
|
WO2016149537A1
(en)
|
2015-03-17 |
2016-09-22 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Bank vole prion protein as a broad-spectrum substrate for rt-quic-based detection and discrimination of prion strains
|
TN2017000432A1
(en)
|
2015-04-10 |
2019-04-12 |
Amgen Inc |
Interleukin-2 muteins for the expansion of t-regulatory cells
|
LT3283524T
(lt)
|
2015-04-17 |
2023-05-25 |
Amgen Research (Munich) Gmbh |
Bispecifiniai antikūnų konstruktai, skirti cdh3 ir cd3
|
TWI793062B
(zh)
|
2015-07-31 |
2023-02-21 |
德商安美基研究(慕尼黑)公司 |
Dll3及cd3抗體構築體
|
TWI796283B
(zh)
|
2015-07-31 |
2023-03-21 |
德商安美基研究(慕尼黑)公司 |
Msln及cd3抗體構築體
|
TWI717375B
(zh)
|
2015-07-31 |
2021-02-01 |
德商安美基研究(慕尼黑)公司 |
Cd70及cd3抗體構築體
|
TWI829617B
(zh)
|
2015-07-31 |
2024-01-21 |
德商安美基研究(慕尼黑)公司 |
Flt3及cd3抗體構築體
|
TWI744242B
(zh)
|
2015-07-31 |
2021-11-01 |
德商安美基研究(慕尼黑)公司 |
Egfrviii及cd3抗體構築體
|
EP3932953A1
(en)
|
2015-08-28 |
2022-01-05 |
F. Hoffmann-La Roche AG |
Anti-hypusine antibodies and uses thereof
|
EP3387018A1
(en)
|
2015-12-11 |
2018-10-17 |
Dyax Corp. |
Plasma kallikrein inhibitors and uses thereof for treating hereditary angioedema attack
|
JOP20170017B1
(ar)
|
2016-01-25 |
2021-08-17 |
Amgen Res Munich Gmbh |
تركيب صيدلي يتضمن تركيبات جسم مضاد ثنائي الاختصاص
|
EP3411402B1
(en)
|
2016-02-03 |
2021-12-22 |
Amgen Research (Munich) GmbH |
Bcma and cd3 bispecific t cell engaging antibody constructs
|
KR20180101623A
(ko)
|
2016-02-03 |
2018-09-12 |
암젠 리서치 (뮌헨) 게엠베하 |
Psma 및 cd3 이중특이성 t 세포 맞물림 항체 작제물
|
EA039859B1
(ru)
|
2016-02-03 |
2022-03-21 |
Эмджен Рисерч (Мюник) Гмбх |
Биспецифические конструкты антител, связывающие egfrviii и cd3
|
JOP20170091B1
(ar)
|
2016-04-19 |
2021-08-17 |
Amgen Res Munich Gmbh |
إعطاء تركيبة ثنائية النوعية ترتبط بـ cd33 وcd3 للاستخدام في طريقة لعلاج اللوكيميا النخاعية
|
CN115073581A
(zh)
|
2016-05-04 |
2022-09-20 |
美国安进公司 |
用于扩增t调节性细胞的白细胞介素-2突变蛋白
|
AU2017268198C1
(en)
|
2016-05-16 |
2020-11-26 |
Takeda Pharmaceutical Company Limited |
Anti-Factor IX Padua antibodies
|
EP3484923A1
(en)
|
2016-07-15 |
2019-05-22 |
Takeda Pharmaceutical Company Limited |
Methods and materials for assessing response to plasmablast- and plasma cell-depleting therapies
|
JP7105238B2
(ja)
|
2017-01-18 |
2022-07-22 |
ジェネンテック, インコーポレイテッド |
抗pd-l1抗体に対するイディオタイプ抗体及びそれらの使用
|
JOP20190189A1
(ar)
|
2017-02-02 |
2019-08-01 |
Amgen Res Munich Gmbh |
تركيبة صيدلانية ذات درجة حموضة منخفضة تتضمن بنيات جسم مضاد يستهدف الخلية t
|
GB201703876D0
(en)
|
2017-03-10 |
2017-04-26 |
Berlin-Chemie Ag |
Pharmaceutical combinations
|
KR20190141243A
(ko)
|
2017-05-05 |
2019-12-23 |
암젠 인크 |
개선된 저장 및 투여를 위한 이중특이적 항체 구축물을 포함하는 약제학적 조성물
|
JP2020536967A
(ja)
|
2017-10-12 |
2020-12-17 |
イミュノウェイク インコーポレイテッド |
Vegfr−抗体軽鎖融合タンパク質
|
TWI827570B
(zh)
|
2017-12-11 |
2024-01-01 |
美商安進公司 |
雙特異性抗體產品之連續製造製程
|
TW201940518A
(zh)
|
2017-12-29 |
2019-10-16 |
美商安進公司 |
針對muc17和cd3之雙特異性抗體構建體
|
AU2019264364A1
(en)
|
2018-04-30 |
2020-11-12 |
Medimmune Limited |
Conjugates for targeting and clearing aggregates
|
GB201809746D0
(en)
|
2018-06-14 |
2018-08-01 |
Berlin Chemie Ag |
Pharmaceutical combinations
|
JOP20200343A1
(ar)
|
2018-07-02 |
2020-12-31 |
Xencor Inc |
بروتين ربط مولد ضد مضاد لـ steap1
|
EP3830121A1
(en)
|
2018-07-30 |
2021-06-09 |
Amgen Research (Munich) GmbH |
Prolonged administration of a bispecific antibody construct binding to cd33 and cd3
|
JP2022512636A
(ja)
|
2018-10-11 |
2022-02-07 |
アムジエン・インコーポレーテツド |
二重特異性抗体コンストラクトの下流プロセシング
|
WO2020081493A1
(en)
|
2018-10-16 |
2020-04-23 |
Molecular Templates, Inc. |
Pd-l1 binding proteins
|
EP3983520A1
(en)
|
2019-06-13 |
2022-04-20 |
Amgen, Inc |
Automated biomass-based perfusion control in the manufacturing of biologics
|
US20220289807A1
(en)
|
2019-08-13 |
2022-09-15 |
Amgen Inc. |
Interleukin-2 muteins for the expansion of t-regulatory cells
|
JP2022547135A
(ja)
|
2019-09-10 |
2022-11-10 |
アムジエン・インコーポレーテツド |
増強されたプロテインl捕捉動的結合容量を有する二重特異性抗原結合ポリペプチドの精製方法
|
WO2021097344A1
(en)
|
2019-11-13 |
2021-05-20 |
Amgen Inc. |
Method for reduced aggregate formation in downstream processing of bispecific antigen-binding molecules
|
EP4077383A1
(en)
|
2019-12-17 |
2022-10-26 |
Amgen Inc. |
Dual interleukin-2 /tnf receptor agonist for use in therapy
|
IL297672A
(en)
|
2020-04-30 |
2022-12-01 |
Genentech Inc |
Antibodies specific to kras and uses thereof
|
US20220017636A1
(en)
|
2020-05-19 |
2022-01-20 |
Amgen Inc. |
Mageb2 binding constructs
|
TW202210101A
(zh)
|
2020-05-29 |
2022-03-16 |
美商安進公司 |
與cd33和cd3結合的雙特異性構建體的減輕不良反應投與
|
CA3182473A1
(en)
|
2020-06-01 |
2021-12-09 |
Genentech, Inc. |
Methods for making extracellular vesicles and uses thereof
|
WO2021259227A1
(zh)
|
2020-06-23 |
2021-12-30 |
江苏康缘药业股份有限公司 |
抗cd38抗体及其用途
|
JP2023533813A
(ja)
|
2020-07-14 |
2023-08-04 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
一定用量配合剤のアッセイ
|
EP4240768A2
(en)
|
2020-11-06 |
2023-09-13 |
Amgen Inc. |
Multitargeting bispecific antigen-binding molecules of increased selectivity
|
AR125290A1
(es)
|
2021-04-02 |
2023-07-05 |
Amgen Inc |
Construcciones de unión a mageb2
|
WO2022234102A1
(en)
|
2021-05-06 |
2022-11-10 |
Amgen Research (Munich) Gmbh |
Cd20 and cd22 targeting antigen-binding molecules for use in proliferative diseases
|
CN113372514B
(zh)
*
|
2021-06-22 |
2022-06-14 |
安徽农业大学 |
一种刀豆蛋白聚合物水凝胶的制备方法、制得的水凝胶及其应用
|
WO2023218027A1
(en)
|
2022-05-12 |
2023-11-16 |
Amgen Research (Munich) Gmbh |
Multichain multitargeting bispecific antigen-binding molecules of increased selectivity
|
WO2024059675A2
(en)
|
2022-09-14 |
2024-03-21 |
Amgen Inc. |
Bispecific molecule stabilizing composition
|