CH593992A5
(da)
*
|
1972-12-23 |
1977-12-30 |
Roehm Gmbh |
|
GB1550819A
(en)
*
|
1975-06-04 |
1979-08-22 |
Nat Res Dev |
Polymeric support for biogically active materials
|
JPS5272284A
(en)
*
|
1975-12-12 |
1977-06-16 |
Dainippon Pharmaceutical Co |
Enzymeeimmunoassay reagent
|
US4108804A
(en)
*
|
1975-12-23 |
1978-08-22 |
Toru Seita |
Process for preparation of chromatography solid supports comprising a nucleic acid base-epoxy group containing porous gel
|
US4046723A
(en)
*
|
1976-04-22 |
1977-09-06 |
The Dow Chemical Company |
Azide bonding of a protein to a latex
|
US4179423A
(en)
*
|
1976-06-09 |
1979-12-18 |
Schenectady Chemicals, Inc. |
Water-soluble polyester imide resins
|
US4206261A
(en)
*
|
1976-06-09 |
1980-06-03 |
Schenectady Chemicals, Inc. |
Water-soluble polyester imide resin wire coating process
|
US4045384A
(en)
*
|
1976-07-23 |
1977-08-30 |
The Dow Chemical Company |
Method for forming an amide bond between a latex and protein
|
DE2708018A1
(de)
*
|
1977-02-24 |
1978-09-07 |
Boehringer Mannheim Gmbh |
An polyamid fixiertes biologisch aktives protein und verfahren zu seiner herstellung
|
IT1107772B
(it)
*
|
1977-08-22 |
1985-11-25 |
Cancer Res Inst Royal |
Procedimento per la produzione di complessi macromolecolari prodotto ottenuto e composizioni farmaceutiche che lo contengono come ingrediente attivo
|
US4206286A
(en)
*
|
1977-11-14 |
1980-06-03 |
Technicon Instruments Corporation |
Immobilization of proteins on inorganic supports
|
US4338398A
(en)
*
|
1979-03-20 |
1982-07-06 |
Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo |
Immobilization of starch degrading enzymes
|
US4415665A
(en)
*
|
1980-12-12 |
1983-11-15 |
Pharmacia Fine Chemicals Ab |
Method of covalently binding biologically active organic substances to polymeric substances
|
DE3126551C2
(de)
*
|
1981-07-04 |
1983-12-15 |
Rolf Dr. 8700 Würzburg Siegel |
Herstellungsverfahren für Materialien zur Immobilisierung von Proteinen und Kohlenhydratgruppen
|
US4506019A
(en)
*
|
1982-09-24 |
1985-03-19 |
Leeco Diagnostics, Inc. |
Activated polymer container means and assay method employing the same
|
US4596777A
(en)
*
|
1983-08-10 |
1986-06-24 |
E. R. Squibb & Sons, Inc. |
Process for preparing (3S)-3-[[[2-(protected or unprotected amino)-4-thiazolyl]acetyl]amino]-2-oxo-1-azetidinesulfonic acid and 4-substituted derivatives thereof
|
US4843010A
(en)
*
|
1983-11-10 |
1989-06-27 |
Genetic Systems Corporation |
Polymerization-induced separation immunoassays
|
US4711840A
(en)
*
|
1984-01-27 |
1987-12-08 |
Genetic Systems Corporation |
Polymerization-induced separation immunoassays
|
US4609707A
(en)
*
|
1983-11-10 |
1986-09-02 |
Genetic Systems Corporation |
Synthesis of polymers containing integral antibodies
|
EP0142810B1
(en)
*
|
1983-11-10 |
1994-02-16 |
Genetic Systems Corporation |
Polymerizable compounds integrally containing antibodies and their uses in polymerization induced separation immunoassays
|
US4752638A
(en)
*
|
1983-11-10 |
1988-06-21 |
Genetic Systems Corporation |
Synthesis and use of polymers containing integral binding-pair members
|
US4511478A
(en)
*
|
1983-11-10 |
1985-04-16 |
Genetic Systems Corporation |
Polymerizable compounds and methods for preparing synthetic polymers that integrally contain polypeptides
|
JPH0820447B2
(ja)
*
|
1984-01-27 |
1996-03-04 |
ジェネティック システムズ コーポレーション |
液体混合物から物質を分離する方法及び免疫評価法
|
US4695624A
(en)
*
|
1984-05-10 |
1987-09-22 |
Merck & Co., Inc. |
Covalently-modified polyanionic bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins with bigeneric spacers, and methods of preparing such polysaccharides and conjugates and of confirming covalency
|
US4749647A
(en)
*
|
1984-06-22 |
1988-06-07 |
Genetic Systems Corporation |
Polymerization-induced separation assay using recognition pairs
|
ES2044933T3
(es)
*
|
1986-08-07 |
1994-01-16 |
Minnesota Mining & Mfg |
Emulsiones de productos quimicos fluorados, biologicamente activas y estables.
|
US4808530A
(en)
*
|
1986-09-05 |
1989-02-28 |
The Ohio State University |
Protein immobilization by adsorption of a hydrophobic amidine protein derivative to a hydrophobic surface
|
US4885250A
(en)
*
|
1987-03-02 |
1989-12-05 |
E. I. Du Pont De Nemours And Company |
Enzyme immobilization and bioaffinity separations with perfluorocarbon polymer-based supports
|
US5063109A
(en)
*
|
1988-10-11 |
1991-11-05 |
Abbott Laboratories |
Covalent attachment of antibodies and antigens to solid phases using extended length heterobifunctional coupling agents
|
US5116964A
(en)
|
1989-02-23 |
1992-05-26 |
Genentech, Inc. |
Hybrid immunoglobulins
|
EP0473961B1
(en)
*
|
1990-08-15 |
1996-01-03 |
Abbott Laboratories |
Immunoassay reagents and method for determining cyclosporine
|
US5612034A
(en)
*
|
1990-10-03 |
1997-03-18 |
Redcell, Inc. |
Super-globuling for in vivo extended lifetimes
|
US5482996A
(en)
*
|
1993-12-08 |
1996-01-09 |
University Of Pittsburgh |
Protein-containing polymers and a method of synthesis of protein-containing polymers in organic solvents
|
US6057287A
(en)
|
1994-01-11 |
2000-05-02 |
Dyax Corp. |
Kallikrein-binding "Kunitz domain" proteins and analogues thereof
|
US5795865A
(en)
*
|
1994-01-11 |
1998-08-18 |
Dyax Corp. |
Kallikrein-inhibiting "kunitz domain" proteins and analogues thereof
|
US6045797A
(en)
*
|
1994-03-14 |
2000-04-04 |
New York University Medical Center |
Treatment or diagnosis of diseases or conditions associated with a BLM domain
|
US5877016A
(en)
|
1994-03-18 |
1999-03-02 |
Genentech, Inc. |
Human trk receptors and neurotrophic factor inhibitors
|
US5708142A
(en)
|
1994-05-27 |
1998-01-13 |
Genentech, Inc. |
Tumor necrosis factor receptor-associated factors
|
US5736624A
(en)
*
|
1994-12-02 |
1998-04-07 |
Abbott Laboratories |
Phosphatase activated crosslinking, conjugating and reducing agents; methods of using such agents; and reagents comprising phosphatase activated crosslinking and conjugating agents
|
US5837815A
(en)
*
|
1994-12-15 |
1998-11-17 |
Sugen, Inc. |
PYK2 related polypeptide products
|
US5837524A
(en)
*
|
1994-12-15 |
1998-11-17 |
Sugen, Inc. |
PYK2 related polynucleotide products
|
US5807989A
(en)
*
|
1994-12-23 |
1998-09-15 |
New York University |
Methods for treatment or diagnosis of diseases or disorders associated with an APB domain
|
US6300482B1
(en)
*
|
1995-01-03 |
2001-10-09 |
Max-Flanck-Gesellschaft Zuer For{Overscore (D)}Erung Der |
MDKI, a novel receptor tyrosine kinase
|
US6565842B1
(en)
*
|
1995-06-07 |
2003-05-20 |
American Bioscience, Inc. |
Crosslinkable polypeptide compositions
|
US7005505B1
(en)
|
1995-08-25 |
2006-02-28 |
Genentech, Inc. |
Variants of vascular endothelial cell growth factor
|
US6020473A
(en)
*
|
1995-08-25 |
2000-02-01 |
Genentech, Inc. |
Nucleic acids encoding variants of vascular endothelial cell growth factor
|
WO1997010337A1
(en)
|
1995-09-15 |
1997-03-20 |
Baylor College Of Medicine |
Steroid receptor coactivator compositions and methods of use
|
US6030945A
(en)
*
|
1996-01-09 |
2000-02-29 |
Genentech, Inc. |
Apo-2 ligand
|
US6046048A
(en)
*
|
1996-01-09 |
2000-04-04 |
Genetech, Inc. |
Apo-2 ligand
|
US20050089958A1
(en)
*
|
1996-01-09 |
2005-04-28 |
Genentech, Inc. |
Apo-2 ligand
|
US6998116B1
(en)
*
|
1996-01-09 |
2006-02-14 |
Genentech, Inc. |
Apo-2 ligand
|
JP2000507829A
(ja)
*
|
1996-04-01 |
2000-06-27 |
ジェネンテック インコーポレーテッド |
Apo―2liおよびapo―3アポトーシスポリペプチド
|
US20020165157A1
(en)
*
|
1996-04-01 |
2002-11-07 |
Genentech, Inc. |
Apo-2LI and Apo-3 polypeptides
|
US6100071A
(en)
|
1996-05-07 |
2000-08-08 |
Genentech, Inc. |
Receptors as novel inhibitors of vascular endothelial growth factor activity and processes for their production
|
US5851984A
(en)
*
|
1996-08-16 |
1998-12-22 |
Genentech, Inc. |
Method of enhancing proliferation or differentiation of hematopoietic stem cells using Wnt polypeptides
|
US6159462A
(en)
*
|
1996-08-16 |
2000-12-12 |
Genentech, Inc. |
Uses of Wnt polypeptides
|
US6462176B1
(en)
|
1996-09-23 |
2002-10-08 |
Genentech, Inc. |
Apo-3 polypeptide
|
ATE356212T1
(de)
|
1997-01-31 |
2007-03-15 |
Genentech Inc |
O-fukosyltransferase
|
US20040241645A1
(en)
*
|
1997-01-31 |
2004-12-02 |
Genentech, Inc. |
O-fucosyltransferase
|
US20020102706A1
(en)
*
|
1997-06-18 |
2002-08-01 |
Genentech, Inc. |
Apo-2DcR
|
US6342369B1
(en)
*
|
1997-05-15 |
2002-01-29 |
Genentech, Inc. |
Apo-2-receptor
|
JP2001511653A
(ja)
*
|
1997-05-15 |
2001-08-14 |
ジェネンテク,インコーポレイテッド |
Apo−2レセプター
|
US20100152426A1
(en)
*
|
1997-05-15 |
2010-06-17 |
Ashkenazi Avi J |
Apo-2 receptor fusion proteins
|
WO1998055615A1
(en)
|
1997-06-05 |
1998-12-10 |
The University Of Texas Board Or Regents |
Apaf-1, the ced-4 human homolog, an activator of caspase-3
|
EP1032661A1
(en)
*
|
1997-06-18 |
2000-09-06 |
Genentech, Inc. |
Apo-2DcR
|
AU8569698A
(en)
*
|
1997-07-11 |
1999-02-08 |
Brandeis University |
Method of inducing apoptosis by reducing the level of thiamin
|
JP2001513994A
(ja)
*
|
1997-08-26 |
2001-09-11 |
ジェネンテク・インコーポレイテッド |
Rtdレセプター
|
US20030175856A1
(en)
*
|
1997-08-26 |
2003-09-18 |
Genetech, Inc. |
Rtd receptor
|
US8679534B2
(en)
*
|
1997-12-12 |
2014-03-25 |
Andrx Labs, Llc |
HMG-CoA reductase inhibitor extended release formulation
|
WO1999036535A1
(en)
|
1998-01-15 |
1999-07-22 |
Genentech, Inc. |
Apo-2 ligand
|
CA2328498A1
(en)
*
|
1998-06-12 |
1999-12-16 |
Genentech, Inc. |
Monoclonal antibodies, cross-reactive antibodies and method for producing the same____________________________________
|
US6984719B1
(en)
|
1998-09-17 |
2006-01-10 |
Hospital Sainte-Justine |
Peptide antagonists of prostaglandin F2α receptor
|
US6368793B1
(en)
|
1998-10-14 |
2002-04-09 |
Microgenomics, Inc. |
Metabolic selection methods
|
US6660843B1
(en)
*
|
1998-10-23 |
2003-12-09 |
Amgen Inc. |
Modified peptides as therapeutic agents
|
MEP42108A
(en)
|
1998-10-23 |
2011-02-10 |
Kiren Amgen Inc |
Dimeric thrombopoietin peptide mimetics binding to mp1 receptor and having thrombopoietic activity
|
US6982153B1
(en)
|
1998-12-03 |
2006-01-03 |
Targanta Therapeutics, Inc. |
DNA sequences from staphylococcus aureus bacteriophage 77 that encode anti-microbial polypeptides
|
US6861442B1
(en)
|
1998-12-30 |
2005-03-01 |
Sugen, Inc. |
PYK2 and inflammation
|
EP1192258A2
(en)
*
|
1999-06-16 |
2002-04-03 |
Icos Corporation |
Human poly(adp-ribose) polymerase 2 materials and methods
|
US20040235749A1
(en)
*
|
1999-09-15 |
2004-11-25 |
Sylvain Chemtob |
G-protein coupled receptor antagonists
|
US20030138771A1
(en)
*
|
1999-09-30 |
2003-07-24 |
Jerry Pelletier |
DNA sequences from S. pneumoniae bacteriophage DP1 that encode anti-microbal polypeptides
|
US6808902B1
(en)
|
1999-11-12 |
2004-10-26 |
Amgen Inc. |
Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
|
ATE315789T1
(de)
*
|
1999-11-16 |
2006-02-15 |
Genentech Inc |
Elisa für vegf
|
AU2001257173B2
(en)
|
2000-04-21 |
2005-09-22 |
Amgen Inc. |
Apo-ai/aii peptide derivatives
|
US6667300B2
(en)
|
2000-04-25 |
2003-12-23 |
Icos Corporation |
Inhibitors of human phosphatidylinositol 3-kinase delta
|
US6677136B2
(en)
|
2000-05-03 |
2004-01-13 |
Amgen Inc. |
Glucagon antagonists
|
AU8330401A
(en)
*
|
2000-08-11 |
2002-02-25 |
Favrille Inc |
Method and composition for altering a t cell mediated pathology
|
US6911204B2
(en)
|
2000-08-11 |
2005-06-28 |
Favrille, Inc. |
Method and composition for altering a B cell mediated pathology
|
CA2446189C
(en)
|
2001-05-11 |
2011-10-18 |
Amgen, Inc. |
Peptides and related molecules that bind to tall-1
|
EP2292271A3
(en)
|
2001-10-10 |
2011-09-14 |
BioGeneriX AG |
Remodelling and glycoconjugation of an antibody
|
EP2298354B1
(en)
|
2001-10-10 |
2014-03-19 |
ratiopharm GmbH |
Remodelling and glycoconjugation of interferon-beta
|
US7332474B2
(en)
*
|
2001-10-11 |
2008-02-19 |
Amgen Inc. |
Peptides and related compounds having thrombopoietic activity
|
US7138370B2
(en)
|
2001-10-11 |
2006-11-21 |
Amgen Inc. |
Specific binding agents of human angiopoietin-2
|
US20040054082A1
(en)
*
|
2001-12-03 |
2004-03-18 |
Bank David H |
Toughened polymer blends with improved surface properties
|
US20100311954A1
(en)
*
|
2002-03-01 |
2010-12-09 |
Xencor, Inc. |
Optimized Proteins that Target Ep-CAM
|
US7153829B2
(en)
*
|
2002-06-07 |
2006-12-26 |
Dyax Corp. |
Kallikrein-inhibitor therapies
|
DK1531791T3
(da)
*
|
2002-06-07 |
2010-11-01 |
Dyax Corp |
Forebyggelse og begrænsning af iskæmi
|
US7521530B2
(en)
|
2002-06-11 |
2009-04-21 |
Universite De Montreal |
Peptides and peptidomimetics useful for inhibiting the activity of prostaglandin F2α receptor
|
ES2395014T3
(es)
*
|
2002-08-28 |
2013-02-07 |
Dyax Corp. |
Métodos para conservar órganos y tejidos
|
US6919426B2
(en)
|
2002-09-19 |
2005-07-19 |
Amgen Inc. |
Peptides and related molecules that modulate nerve growth factor activity
|
PL1615945T3
(pl)
|
2003-04-09 |
2012-03-30 |
Ratiopharm Gmbh |
Sposoby glikopegylacji i białka/peptydy wytwarzane tymi sposobami
|
WO2005016348A1
(en)
*
|
2003-08-14 |
2005-02-24 |
Icos Corporation |
Method of inhibiting immune responses stimulated by an endogenous factor
|
US20050054614A1
(en)
*
|
2003-08-14 |
2005-03-10 |
Diacovo Thomas G. |
Methods of inhibiting leukocyte accumulation
|
US8883147B2
(en)
|
2004-10-21 |
2014-11-11 |
Xencor, Inc. |
Immunoglobulins insertions, deletions, and substitutions
|
US20060134105A1
(en)
*
|
2004-10-21 |
2006-06-22 |
Xencor, Inc. |
IgG immunoglobulin variants with optimized effector function
|
US8399618B2
(en)
|
2004-10-21 |
2013-03-19 |
Xencor, Inc. |
Immunoglobulin insertions, deletions, and substitutions
|
AR046601A1
(es)
*
|
2003-10-22 |
2005-12-14 |
Merz Pharma Gmbh & Co Kgaa |
Uso de derivados 1- aminociclohexano para modificar la deposicion de peptidos ab fibrosos en amiloidopatias
|
US7422741B2
(en)
|
2004-03-05 |
2008-09-09 |
Vegenics Limited |
VEGFR-3 fusion proteins
|
MXPA06011824A
(es)
*
|
2004-04-16 |
2006-12-15 |
Genentech Inc |
Ensayo para anticuerpos.
|
US7932260B2
(en)
|
2004-05-13 |
2011-04-26 |
Icos Corporation |
Quinazolinones as inhibitors of human phosphatidylinositol 3-kinase delta
|
WO2005114218A2
(en)
*
|
2004-05-15 |
2005-12-01 |
Genentech, Inc. |
Cross-screening system and methods for detecting a molecule having binding affinity for a target molecule
|
EP1755609A1
(en)
*
|
2004-05-25 |
2007-02-28 |
Icos Corporation |
Methods for treating and/or preventing aberrant proliferation of hematopoietic cells
|
EP1773400A2
(en)
*
|
2004-07-08 |
2007-04-18 |
Amgen Inc. |
Therapeutic peptides
|
EP1797127B1
(en)
|
2004-09-24 |
2017-06-14 |
Amgen Inc. |
Modified fc molecules
|
US7235530B2
(en)
*
|
2004-09-27 |
2007-06-26 |
Dyax Corporation |
Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
|
DK1817340T3
(da)
|
2004-11-12 |
2012-08-13 |
Xencor Inc |
Fc-varianter med ændret binding til fcrn
|
US8802820B2
(en)
|
2004-11-12 |
2014-08-12 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
EP2290086A3
(en)
|
2004-12-22 |
2011-10-19 |
Genentech, Inc. |
Methods for producing soluble multi-membrane-spanning proteins
|
CA2598409A1
(en)
*
|
2005-02-17 |
2006-08-24 |
Icos Corporation |
Phosphoinositide 3-kinase inhibitors for inhibiting leukocyte accumulation
|
US7557190B2
(en)
|
2005-07-08 |
2009-07-07 |
Xencor, Inc. |
Optimized proteins that target Ep-CAM
|
US8008453B2
(en)
|
2005-08-12 |
2011-08-30 |
Amgen Inc. |
Modified Fc molecules
|
WO2007056411A2
(en)
*
|
2005-11-08 |
2007-05-18 |
Genentech, Inc. |
Method of producing pan-specific antibodies
|
PE20070684A1
(es)
|
2005-11-14 |
2007-08-06 |
Amgen Inc |
MOLECULAS QUIMERICAS DE ANTICUERPO RANKL-PTH/PTHrP
|
US7276480B1
(en)
|
2005-12-30 |
2007-10-02 |
Dyax Corp. |
Prevention and reduction of blood loss
|
WO2007102946A2
(en)
|
2006-01-23 |
2007-09-13 |
Amgen Inc. |
Crystalline polypeptides
|
EP2001500A4
(en)
*
|
2006-03-10 |
2010-07-28 |
Dyax Corp |
FORMULATIONS FOR ECALLANTIDE
|
US9283260B2
(en)
|
2006-04-21 |
2016-03-15 |
Amgen Inc. |
Lyophilized therapeutic peptibody formulations
|
US7981425B2
(en)
|
2006-06-19 |
2011-07-19 |
Amgen Inc. |
Thrombopoietic compounds
|
ES2376396T3
(es)
|
2006-06-26 |
2012-03-13 |
Amgen Inc. |
Método para tratar aterosclerosis.
|
ATE531727T1
(de)
|
2006-09-18 |
2011-11-15 |
Compugen Ltd |
Bioaktive peptide und verfahren zu ihrer verwendung
|
US7833527B2
(en)
|
2006-10-02 |
2010-11-16 |
Amgen Inc. |
Methods of treating psoriasis using IL-17 Receptor A antibodies
|
PL2457929T3
(pl)
|
2006-10-04 |
2016-12-30 |
|
Test ELISA dla VEGF
|
WO2008051383A2
(en)
*
|
2006-10-19 |
2008-05-02 |
Amgen Inc. |
Use of alcohol co-solvents to improve pegylation reaction yields
|
AR063384A1
(es)
*
|
2006-10-25 |
2009-01-28 |
Amgen Inc |
Agentes terapeuticos a base de peptidos derivados de toxinas
|
WO2008079322A1
(en)
*
|
2006-12-22 |
2008-07-03 |
Beckman Coulter, Inc. |
Methods, kits and materials for diagnosing disease states by measuring isoforms or proforms of myeloperoxidase
|
AU2008262490B2
(en)
*
|
2007-05-22 |
2011-11-17 |
Amgen Inc. |
Compositions and methods for producing bioactive fusion proteins
|
US8492329B2
(en)
|
2007-07-12 |
2013-07-23 |
Compugen Ltd. |
Bioactive peptides and methods of using same
|
ES2513716T3
(es)
|
2007-07-26 |
2014-10-27 |
Amgen, Inc |
Enzimas lecitina-colesteros acitransferasa modificadas
|
EP2201024A1
(en)
|
2007-08-28 |
2010-06-30 |
Ramot At Tel Aviv University |
Peptides inducing a cd4i conformation in hiv gp120 while retaining vacant cd4 binding site
|
ES2532461T3
(es)
|
2007-12-26 |
2015-03-27 |
Xencor, Inc. |
Variantes de FC con enlazamiento alterado a FCRN
|
WO2010027802A2
(en)
|
2008-08-25 |
2010-03-11 |
New York University |
Methods for treating diabetic wounds
|
US9492449B2
(en)
|
2008-11-13 |
2016-11-15 |
Gilead Calistoga Llc |
Therapies for hematologic malignancies
|
CA2975473C
(en)
|
2008-11-13 |
2021-01-19 |
Gilead Calistoga Llc |
Therapies for hematologic malignancies
|
WO2010080833A1
(en)
*
|
2009-01-06 |
2010-07-15 |
Dyax Corp. |
Treatment of mucositis with kallikrein inhibitors
|
JP2012521994A
(ja)
|
2009-03-24 |
2012-09-20 |
ギリアード カリストガ エルエルシー |
2−プリニル−3−トリル−キナゾリノン誘導体のアトロプ異性体および使用方法
|
ES2548253T3
(es)
*
|
2009-04-20 |
2015-10-15 |
Gilead Calistoga Llc |
Métodos para el tratamiento de tumores sólidos
|
CA2768843A1
(en)
|
2009-07-21 |
2011-01-27 |
Gilead Calistoga Llc |
Treatment of liver disorders with pi3k inhibitors
|
TW201117824A
(en)
|
2009-10-12 |
2011-06-01 |
Amgen Inc |
Use of IL-17 receptor a antigen binding proteins
|
WO2011049625A1
(en)
|
2009-10-20 |
2011-04-28 |
Mansour Samadpour |
Method for aflatoxin screening of products
|
HUE033492T2
(en)
*
|
2009-10-26 |
2017-12-28 |
Genentech Inc |
Tests for the detection of antibodies specific for therapeutic anti-verb antibodies and their use in anaphylaxis
|
MY173795A
(en)
|
2009-11-05 |
2020-02-24 |
Incozen Therapeutics Pvt Ltd |
Novel benzopyran kinase modulators
|
RS57870B1
(sr)
|
2010-01-06 |
2018-12-31 |
Dyax Corp |
Proteini koji vezuju kalikrein plazme
|
WO2011097527A2
(en)
|
2010-02-04 |
2011-08-11 |
Xencor, Inc. |
Immunoprotection of therapeutic moieties using enhanced fc regions
|
US20110189178A1
(en)
*
|
2010-02-04 |
2011-08-04 |
Xencor, Inc. |
Immunoprotection of Therapeutic Moieties Using Enhanced Fc Regions
|
EP2547359B1
(en)
|
2010-03-15 |
2016-03-09 |
The Board of Trustees of the University of Illionis |
Inhibitors of beta integrin-g protein alpha subunit binding interactions
|
JP5960688B2
(ja)
|
2010-05-17 |
2016-08-02 |
インコゼン セラピューティクス プライベート リミテッド |
プロテインキナーゼ調節物質としての新規3,5−二置換−3h−[1,2,3]トリアゾロ[4,5−b]ピリジン化合物
|
EP3272352B1
(en)
|
2010-06-17 |
2022-04-13 |
New York University |
Therapeutic and cosmetic uses and applications of calreticulin
|
WO2012030738A2
(en)
|
2010-08-30 |
2012-03-08 |
Beckman Coulter, Inc. |
Complex phosphoprotein activation profiles
|
EP3828205A1
(en)
|
2010-10-01 |
2021-06-02 |
Oxford BioTherapeutics Ltd |
Anti-ror1 antibodies
|
EP2655401B1
(en)
|
2010-12-20 |
2016-03-09 |
The Regents of the University of Michigan |
Inhibitors of the epidermal growth factor receptor-heat shock protein 90 binding interaction
|
JOP20210044A1
(ar)
|
2010-12-30 |
2017-06-16 |
Takeda Pharmaceuticals Co |
الأجسام المضادة لـ cd38
|
KR102107695B1
(ko)
|
2011-01-06 |
2020-05-07 |
다이액스 코포레이션 |
혈장 칼리크레인 결합 단백질
|
EP2686340A2
(en)
|
2011-03-16 |
2014-01-22 |
Amgen Inc. |
Potent and selective inhibitors of nav1.3 and nav1.7
|
BR112013027867A2
(pt)
|
2011-04-29 |
2016-09-06 |
Bristol Myers Squibb Co |
"método de detectar o nível de um anticorpo anti-ip10 em amostra, anticorpo monoclonal isolado ou porção de ligação de antígeno do mesmo, linhagem de célula de hibridoma e kit"
|
MY168757A
(en)
|
2011-05-04 |
2018-12-04 |
Rhizen Pharmaceuticals S A |
Novel compounds as modulators of protein kinases
|
US20140234330A1
(en)
|
2011-07-22 |
2014-08-21 |
Amgen Inc. |
Il-17 receptor a is required for il-17c biology
|
KR102007055B1
(ko)
|
2011-09-22 |
2019-08-02 |
암젠 인크 |
Cd27l 항원 결합 단백질
|
US10851178B2
(en)
|
2011-10-10 |
2020-12-01 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
WO2013134288A1
(en)
|
2012-03-05 |
2013-09-12 |
Gilead Calistoga Llc |
Polymorphic forms of (s)-2-(1-(9h-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3h)-one
|
US20150079100A1
(en)
|
2012-03-23 |
2015-03-19 |
Bristol-Myers Squibb Company |
Methods of treatments using ctla-4 antibodies
|
US9139659B2
(en)
*
|
2012-03-28 |
2015-09-22 |
Genentech, Inc. |
Idiotypic antibodies and uses thereof
|
WO2013144737A2
(en)
|
2012-03-30 |
2013-10-03 |
Rhizen Pharmaceuticals Sa |
Novel 3,5-disubstitued-3h-imidazo[4,5-b]pyridine and 3,5- disubstitued -3h-[1,2,3]triazolo[4,5-b] pyridine compounds as modulators of c-met protein kinases
|
WO2013155346A1
(en)
|
2012-04-11 |
2013-10-17 |
The Regents Of The University Of California |
Diagnostic tools for response to 6-thiopurine therapy
|
AR091069A1
(es)
|
2012-05-18 |
2014-12-30 |
Amgen Inc |
Proteinas de union a antigeno dirigidas contra el receptor st2
|
TW201425336A
(zh)
|
2012-12-07 |
2014-07-01 |
Amgen Inc |
Bcma抗原結合蛋白質
|
JP6426107B2
(ja)
|
2012-12-20 |
2018-11-21 |
アムジエン・インコーポレーテツド |
Apj受容体アゴニストおよびその使用
|
JO3519B1
(ar)
|
2013-01-25 |
2020-07-05 |
Amgen Inc |
تركيبات أجسام مضادة لأجل cdh19 و cd3
|
WO2014114801A1
(en)
|
2013-01-25 |
2014-07-31 |
Amgen Inc. |
Antibodies targeting cdh19 for melanoma
|
US20150369821A1
(en)
|
2013-02-06 |
2015-12-24 |
Pieris Ag |
Novel lipocalin-mutein assays for measuring hepcidin concentration
|
CA2901226C
(en)
|
2013-02-18 |
2020-11-17 |
Vegenics Pty Limited |
Vascular endothelial growth factor binding proteins
|
TW201446792A
(zh)
|
2013-03-12 |
2014-12-16 |
Amgen Inc |
Nav1.7之強效及選擇性抑制劑
|
US9546203B2
(en)
|
2013-03-14 |
2017-01-17 |
Amgen Inc. |
Aglycosylated Fc-containing polypeptides with cysteine substitutions
|
AU2014232416B2
(en)
|
2013-03-15 |
2017-09-28 |
Xencor, Inc. |
Modulation of T Cells with Bispecific Antibodies and FC Fusions
|
DK2970383T3
(da)
|
2013-03-15 |
2021-07-05 |
Univ Texas |
Fremgangsmåde til behandling af fibrose
|
EP3936521A1
(en)
|
2013-03-15 |
2022-01-12 |
Xencor, Inc. |
Heterodimeric proteins
|
US9260527B2
(en)
|
2013-03-15 |
2016-02-16 |
Sdix, Llc |
Anti-human CXCR4 antibodies and methods of making same
|
ES2753950T3
(es)
|
2013-03-15 |
2020-04-15 |
Amgen Res Munich Gmbh |
Moléculas de unión monocatenarias que comprenden ABP del extremo N
|
WO2014140368A1
(en)
|
2013-03-15 |
2014-09-18 |
Amgen Research (Munich) Gmbh |
Antibody constructs for influenza m2 and cd3
|
PL3456743T3
(pl)
|
2013-05-30 |
2022-03-07 |
Kiniksa Pharmaceuticals, Ltd. |
Białka wiążące antygen receptora onkostatyny m
|
US20160216262A1
(en)
|
2013-09-12 |
2016-07-28 |
Institut National De La Sante Et De La Recherche Medicale |
Method for In Vitro Quantifying Allo-Antibodies, Auto-Antibodies and/or Therapeutic Antibodies
|
WO2015038888A1
(en)
|
2013-09-13 |
2015-03-19 |
Genentech, Inc. |
Methods and compositions comprising purified recombinant polypeptides
|
AR097648A1
(es)
|
2013-09-13 |
2016-04-06 |
Amgen Inc |
Combinación de factores epigenéticos y compuestos biespecíficos que tienen como diana cd33 y cd3 en el tratamiento de leucemia mieloide
|
RU2016107435A
(ru)
|
2013-09-13 |
2017-10-18 |
Дженентек, Инк. |
Композиции и способы обнаружения и количественного определения белка клеток-хозяев в клеточных линиях и рекомбинантные полипептидные продукты
|
LT3055331T
(lt)
|
2013-10-11 |
2021-03-25 |
Oxford Bio Therapeutics Limited |
Konjuguoti antikūnai prieš ly75, skirti vėžio gydymui
|
JP2017502021A
(ja)
|
2013-12-20 |
2017-01-19 |
ギリアード カリストガ エルエルシー |
ホスファチジルイノシトール3−キナーゼ阻害剤のためのプロセス方法
|
AU2014364414A1
(en)
|
2013-12-20 |
2016-06-30 |
Gilead Calistoga Llc |
Polymorphic forms of a hydrochloride salt of (S) -2-(1-(9H-purin-6-ylamino) propyl) -5-fluoro-3-phenylquinazolin-4 (3H) -one
|
WO2015106311A1
(en)
|
2014-01-17 |
2015-07-23 |
Minomic International Ltd. |
Cell surface prostate cancer antigen for diagnosis
|
AU2015218903B2
(en)
|
2014-02-20 |
2020-10-15 |
Allergan, Inc. |
Complement component C5 antibodies
|
KR20160126054A
(ko)
|
2014-02-27 |
2016-11-01 |
알러간, 인코포레이티드 |
보체 인자 Bb 항체
|
BR112016022318A2
(pt)
|
2014-03-27 |
2017-10-31 |
Dyax Corp |
método, composição farmacêutica para uso no tratamento de doenças de retina e uso de um anticorpo
|
KR102497443B1
(ko)
|
2014-03-28 |
2023-02-08 |
젠코어 인코포레이티드 |
Cd38 및 cd3에 결합하는 이중특이적 항체
|
EP4257152A3
(en)
|
2014-06-10 |
2023-12-06 |
Amgen Inc. |
Apelin polypeptides
|
EP3154960A1
(en)
|
2014-06-13 |
2017-04-19 |
Gilead Sciences, Inc. |
Phosphatidylinositol 3-kinase inhibitors
|
AR101669A1
(es)
|
2014-07-31 |
2017-01-04 |
Amgen Res (Munich) Gmbh |
Constructos de anticuerpos para cdh19 y cd3
|
TW201609812A
(zh)
|
2014-07-31 |
2016-03-16 |
安美基研究(慕尼黑)公司 |
最佳化之跨物種特異性雙特異性單鏈抗體構築體
|
WO2016016415A1
(en)
|
2014-07-31 |
2016-02-04 |
Amgen Research (Munich) Gmbh |
Bispecific single chain antibody construct with enhanced tissue distribution
|
US10227411B2
(en)
|
2015-03-05 |
2019-03-12 |
Xencor, Inc. |
Modulation of T cells with bispecific antibodies and FC fusions
|
SI3265557T1
(sl)
|
2015-03-06 |
2020-02-28 |
F. Hoffmann-La Roche Ag |
Ultraprečiščena DsbA in DsbC ter postopki njune izdelave in uporabe
|
WO2016149537A1
(en)
|
2015-03-17 |
2016-09-22 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Bank vole prion protein as a broad-spectrum substrate for rt-quic-based detection and discrimination of prion strains
|
UA126270C2
(uk)
|
2015-04-10 |
2022-09-14 |
Емджен Інк. |
Мутеїни інтерлейкіну-2 для росту регуляторних t-клітин
|
MX2017013348A
(es)
|
2015-04-17 |
2018-08-01 |
Amgen Res Munich Gmbh |
Construcciones de anticuerpos biespecificos contra cdh3 y cd3.
|
TWI744242B
(zh)
|
2015-07-31 |
2021-11-01 |
德商安美基研究(慕尼黑)公司 |
Egfrviii及cd3抗體構築體
|
TWI829617B
(zh)
|
2015-07-31 |
2024-01-21 |
德商安美基研究(慕尼黑)公司 |
Flt3及cd3抗體構築體
|
TWI796283B
(zh)
|
2015-07-31 |
2023-03-21 |
德商安美基研究(慕尼黑)公司 |
Msln及cd3抗體構築體
|
TW202346349A
(zh)
|
2015-07-31 |
2023-12-01 |
德商安美基研究(慕尼黑)公司 |
Dll3及cd3抗體構築體
|
TWI717375B
(zh)
|
2015-07-31 |
2021-02-01 |
德商安美基研究(慕尼黑)公司 |
Cd70及cd3抗體構築體
|
WO2017040342A1
(en)
|
2015-08-28 |
2017-03-09 |
Genentech, Inc. |
Anti-hypusine antibodies and uses thereof
|
BR112018011622A2
(pt)
|
2015-12-11 |
2018-11-27 |
Dyax Corp |
método para tratar ataque de angioedema hereditário (hae) ou reduzir a taxa de ataque de hae
|
TWI797073B
(zh)
|
2016-01-25 |
2023-04-01 |
德商安美基研究(慕尼黑)公司 |
包含雙特異性抗體建構物之醫藥組合物
|
MA43955B1
(fr)
|
2016-02-03 |
2022-02-28 |
Amgen Inc |
Anticorps anti-bcma et anti-cd3 bispécifiques de format bite
|
CN114716557A
(zh)
|
2016-02-03 |
2022-07-08 |
安进研发(慕尼黑)股份有限公司 |
Psma和cd3双特异性t细胞接合抗体构建体
|
EA039859B1
(ru)
|
2016-02-03 |
2022-03-21 |
Эмджен Рисерч (Мюник) Гмбх |
Биспецифические конструкты антител, связывающие egfrviii и cd3
|
JOP20170091B1
(ar)
|
2016-04-19 |
2021-08-17 |
Amgen Res Munich Gmbh |
إعطاء تركيبة ثنائية النوعية ترتبط بـ cd33 وcd3 للاستخدام في طريقة لعلاج اللوكيميا النخاعية
|
KR20180133198A
(ko)
|
2016-05-04 |
2018-12-13 |
암젠 인크 |
T-조절 세포의 증식을 위한 인터류킨-2 뮤테인
|
RU2770006C2
(ru)
|
2016-05-16 |
2022-04-14 |
Такеда Фармасьютикал Компани Лимитед |
Антитела к фактору ix padua
|
CA3030834A1
(en)
|
2016-07-15 |
2018-01-18 |
Takeda Pharmaceutical Company Limited |
Methods and materials for assessing response to plasmablast- and plasma cell-depleting therapies
|
MX2019008348A
(es)
|
2017-01-18 |
2019-10-21 |
Genentech Inc |
Anticuerpos idiotipo contra anticuerpos anti-pd-l1 y usos de estos solicitudes relacionadas.
|
JOP20190189A1
(ar)
|
2017-02-02 |
2019-08-01 |
Amgen Res Munich Gmbh |
تركيبة صيدلانية ذات درجة حموضة منخفضة تتضمن بنيات جسم مضاد يستهدف الخلية t
|
GB201703876D0
(en)
|
2017-03-10 |
2017-04-26 |
Berlin-Chemie Ag |
Pharmaceutical combinations
|
CA3060856A1
(en)
|
2017-05-05 |
2018-11-08 |
Amgen Inc. |
Pharmaceutical composition comprising bispecific antibody constructs for improved storage and administration
|
CA3185107A1
(en)
|
2017-10-12 |
2019-04-18 |
Immunowake Inc. |
Vegfr-antibody light chain fusion protein
|
BR112020011627A2
(pt)
|
2017-12-11 |
2020-11-17 |
Amgen Inc. |
processo de fabricação contínuo para produtos de anticorpos biespecíficos
|
UY38041A
(es)
|
2017-12-29 |
2019-06-28 |
Amgen Inc |
Construcción de anticuerpo biespecífico dirigida a muc17 y cd3
|
US11065336B2
(en)
|
2018-04-30 |
2021-07-20 |
Medimmune Limited |
Conjugates for targeting and clearing aggregates
|
GB201809746D0
(en)
|
2018-06-14 |
2018-08-01 |
Berlin Chemie Ag |
Pharmaceutical combinations
|
SG11202013138RA
(en)
|
2018-07-02 |
2021-01-28 |
Amgen Inc |
Anti-steap1 antigen-binding protein
|
TW202021616A
(zh)
|
2018-07-30 |
2020-06-16 |
美商安進公司 |
結合至cd33和cd3的雙特異性抗體構建體之延長投與
|
US20210395298A1
(en)
|
2018-10-11 |
2021-12-23 |
Amgen Inc. |
Downstream processing of bispecific antibody constructs
|
WO2020081493A1
(en)
|
2018-10-16 |
2020-04-23 |
Molecular Templates, Inc. |
Pd-l1 binding proteins
|
MX2021014644A
(es)
|
2019-06-13 |
2022-04-06 |
Amgen Inc |
Control de perfusion basado en biomasa automatizado en la fabricacion de productos biologicos.
|
MX2022001866A
(es)
|
2019-08-13 |
2022-03-11 |
Amgen Inc |
Muteinas de interleucina-2 para la expansion de celulas t reguladoras.
|
WO2021050640A1
(en)
|
2019-09-10 |
2021-03-18 |
Amgen Inc. |
Purification method for bispecific antigen-binding polypeptides with enhanced protein l capture dynamic binding capacity
|
US20220396599A1
(en)
|
2019-11-13 |
2022-12-15 |
Amgen Inc. |
Method for Reduced Aggregate Formation in Downstream Processing of Bispecific Antigen-Binding Molecules
|
CA3162705A1
(en)
|
2019-12-17 |
2021-06-24 |
Amgen Inc. |
Dual interleukin-2 /tnf receptor agonist for use in therapy
|
US20220112308A1
(en)
|
2020-04-30 |
2022-04-14 |
Genentech, Inc. |
Kras specific antibodies and uses thereof
|
EP4153633A1
(en)
|
2020-05-19 |
2023-03-29 |
Amgen Inc. |
Mageb2 binding constructs
|
MX2022014902A
(es)
|
2020-05-29 |
2023-01-04 |
Amgen Inc |
Administracion mitigadora de efectos adversos de un constructo biespecifico que se une a cd33 y cd3.
|
BR112022024472A2
(pt)
|
2020-06-01 |
2022-12-27 |
Genentech Inc |
Métodos para produzir um anticorpo, para detectar um anticorpo em uma amostra, para classificar células produtoras de anticorpos e para produzir uma pluralidade de vesículas, métodos de produção de um anticorpo e de tratamento de um indivíduo com uma doença, anticorpos isolados, ácido nucleico isolado, célula hospedeira, composição farmacêutica, uso do anticorpo isolado e kit
|
CN116670285A
(zh)
|
2020-06-23 |
2023-08-29 |
江苏康缘药业股份有限公司 |
抗cd38抗体及其用途
|
IL299121A
(en)
|
2020-07-14 |
2023-02-01 |
Hoffmann La Roche |
Tests for fixed dose combinations
|
CN116323671A
(zh)
|
2020-11-06 |
2023-06-23 |
安进公司 |
具有增加的选择性的多靶向性双特异性抗原结合分子
|
WO2022212831A1
(en)
|
2021-04-02 |
2022-10-06 |
Amgen Inc. |
Mageb2 binding constructs
|
CN117279947A
(zh)
|
2021-05-06 |
2023-12-22 |
安进研发(慕尼黑)股份有限公司 |
用于在增殖性疾病中使用的靶向cd20和cd22的抗原结合分子
|
CN113372514B
(zh)
*
|
2021-06-22 |
2022-06-14 |
安徽农业大学 |
一种刀豆蛋白聚合物水凝胶的制备方法、制得的水凝胶及其应用
|
TW202346368A
(zh)
|
2022-05-12 |
2023-12-01 |
德商安美基研究(慕尼黑)公司 |
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