HRP20240115T1 - Povećavanje bioraspoloživosti lijeka u terapiji naltreksonom - Google Patents
Povećavanje bioraspoloživosti lijeka u terapiji naltreksonom Download PDFInfo
- Publication number
- HRP20240115T1 HRP20240115T1 HRP20240115TT HRP20240115T HRP20240115T1 HR P20240115 T1 HRP20240115 T1 HR P20240115T1 HR P20240115T T HRP20240115T T HR P20240115TT HR P20240115 T HRP20240115 T HR P20240115T HR P20240115 T1 HRP20240115 T1 HR P20240115T1
- Authority
- HR
- Croatia
- Prior art keywords
- pharmaceutically acceptable
- acceptable salt
- naltrexone
- bupropion
- use according
- Prior art date
Links
- DQCKKXVULJGBQN-XFWGSAIBSA-N naltrexone Chemical compound N1([C@@H]2CC3=CC=C(C=4O[C@@H]5[C@](C3=4)([C@]2(CCC5=O)O)CC1)O)CC1CC1 DQCKKXVULJGBQN-XFWGSAIBSA-N 0.000 title claims 17
- 229960003086 naltrexone Drugs 0.000 title claims 17
- 238000002560 therapeutic procedure Methods 0.000 title claims 3
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 150000003839 salts Chemical class 0.000 claims 28
- SNPPWIUOZRMYNY-UHFFFAOYSA-N bupropion Chemical compound CC(C)(C)NC(C)C(=O)C1=CC=CC(Cl)=C1 SNPPWIUOZRMYNY-UHFFFAOYSA-N 0.000 claims 14
- 229960001058 bupropion Drugs 0.000 claims 13
- 239000000825 pharmaceutical preparation Substances 0.000 claims 11
- 235000012054 meals Nutrition 0.000 claims 7
- 235000013305 food Nutrition 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 4
- 238000013265 extended release Methods 0.000 claims 3
- 238000009472 formulation Methods 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 208000016261 weight loss Diseases 0.000 claims 3
- 230000004580 weight loss Effects 0.000 claims 3
- 206010056465 Food craving Diseases 0.000 claims 1
- 206010022489 Insulin Resistance Diseases 0.000 claims 1
- 239000002552 dosage form Substances 0.000 claims 1
- 230000002526 effect on cardiovascular system Effects 0.000 claims 1
- 210000001596 intra-abdominal fat Anatomy 0.000 claims 1
- 230000001737 promoting effect Effects 0.000 claims 1
- 230000005586 smoking cessation Effects 0.000 claims 1
- 230000004584 weight gain Effects 0.000 claims 1
- 235000019786 weight gain Nutrition 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M21/00—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Child & Adolescent Psychology (AREA)
- Physics & Mathematics (AREA)
- Acoustics & Sound (AREA)
- Psychology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41939510P | 2010-12-03 | 2010-12-03 | |
| EP21152314.7A EP3884947B1 (en) | 2010-12-03 | 2011-12-02 | Increasing drug bioavailability in naltrexone therapy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20240115T1 true HRP20240115T1 (hr) | 2024-06-07 |
Family
ID=46172304
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20170734TT HRP20170734T1 (hr) | 2010-12-03 | 2011-12-02 | Povećana biodostupnost lijeka u terapiji naltreksonom |
| HRP20240115TT HRP20240115T1 (hr) | 2010-12-03 | 2011-12-02 | Povećavanje bioraspoloživosti lijeka u terapiji naltreksonom |
| HRP20210618TT HRP20210618T1 (hr) | 2010-12-03 | 2021-04-19 | Povećavanje bioraspoloživosti lijeka u terapiji naltreksonom |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20170734TT HRP20170734T1 (hr) | 2010-12-03 | 2011-12-02 | Povećana biodostupnost lijeka u terapiji naltreksonom |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20210618TT HRP20210618T1 (hr) | 2010-12-03 | 2021-04-19 | Povećavanje bioraspoloživosti lijeka u terapiji naltreksonom |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US20130245056A1 (enExample) |
| EP (4) | EP3222280B1 (enExample) |
| JP (5) | JP6008866B2 (enExample) |
| KR (5) | KR102391511B1 (enExample) |
| CN (1) | CN103313711A (enExample) |
| AR (2) | AR093182A1 (enExample) |
| AU (2) | AU2011336304B2 (enExample) |
| BR (1) | BR112013013390A2 (enExample) |
| CA (2) | CA2819262C (enExample) |
| CL (1) | CL2013001564A1 (enExample) |
| CY (2) | CY1118968T1 (enExample) |
| DK (3) | DK3884947T3 (enExample) |
| ES (2) | ES2866879T3 (enExample) |
| FI (1) | FI3884947T3 (enExample) |
| HR (3) | HRP20170734T1 (enExample) |
| HU (3) | HUE065852T2 (enExample) |
| IL (3) | IL226504B (enExample) |
| LT (3) | LT3222280T (enExample) |
| MX (2) | MX384662B (enExample) |
| PL (3) | PL3884947T3 (enExample) |
| PT (3) | PT3222280T (enExample) |
| RS (3) | RS56014B1 (enExample) |
| RU (1) | RU2640561C2 (enExample) |
| SI (3) | SI3222280T1 (enExample) |
| SM (3) | SMT202100227T1 (enExample) |
| TW (1) | TWI618536B (enExample) |
| WO (1) | WO2012075459A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2639579T3 (es) | 2003-04-29 | 2017-10-27 | Orexigen Therapeutics, Inc. | Composiciones para afectar la pérdida de peso que comprende un antagonista opioide y bupropión |
| JP5180092B2 (ja) | 2005-11-22 | 2013-04-10 | オレキシジェン・セラピューティクス・インコーポレーテッド | インスリン感受性を増すための組成物および方法 |
| WO2007089318A2 (en) * | 2005-11-23 | 2007-08-09 | Orexigen Therapeutics, Inc. | Compositions and methods for reducing food cravings |
| US20110144145A1 (en) | 2008-05-30 | 2011-06-16 | Orexigen Therapeutics, Inc. | Methods for treating visceral fat conditions |
| KR20120124423A (ko) | 2010-01-11 | 2012-11-13 | 오렉시젠 세러퓨틱스 인크. | 주우울증 환자들에 있어서 체중 감량 치료를 제공하는 방법 |
| PL3884947T3 (pl) * | 2010-12-03 | 2024-05-06 | Nalpropion Pharmaceuticals Llc | Wzrost biodostępności leku w terapii naltreksonem |
| RS67076B1 (sr) | 2012-06-06 | 2025-08-29 | Nalpropion Pharmaceuticals Llc | Kompozicija za upotrebu u postupku lečenja prekomerne težine i gojaznosti kod pacijenata sa visokim kardiovaskularnim rizikom |
| WO2016125109A1 (en) * | 2015-02-07 | 2016-08-11 | Intas Pharmaceuticals Ltd. | Pharmaceutical composition for the treatment of obesity |
| CN111050801B (zh) * | 2017-03-28 | 2023-03-28 | Ldn制药有限公司 | 用于治疗癌症的增加bcl2-相关的细胞死亡激动剂表达的药剂 |
| EP3482751A1 (en) | 2017-11-14 | 2019-05-15 | LDN Pharma Limited | Cancer treatment |
| US12303604B1 (en) | 2024-10-16 | 2025-05-20 | Currax Pharmaceuticals Llc | Pharmaceutical formulations comprising naltrexone and/or bupropion |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10129265A1 (de) * | 2001-06-18 | 2003-01-02 | Hf Arzneimittelforsch Gmbh | Wirkstoff-Kombination zur medikamentösen Sucht- oder Rauschmitteltherapie |
| US6972291B2 (en) * | 2002-07-02 | 2005-12-06 | Bernstein Richard K | Method for reducing food intake |
| EP1772147A2 (en) * | 2003-03-17 | 2007-04-11 | Japan Tobacco, Inc. | Method for increasing the oral bioavailability of S-[2-([[1-(2-ethylbutyl)cyclohexyl]carbonyl]amino)phenyl]-2-methylpropanethioate |
| ES2639579T3 (es) | 2003-04-29 | 2017-10-27 | Orexigen Therapeutics, Inc. | Composiciones para afectar la pérdida de peso que comprende un antagonista opioide y bupropión |
| KR20080042092A (ko) | 2005-07-27 | 2008-05-14 | 오렉시젠 세러퓨틱스 인크. | 체중감량 조성물 |
| US8921344B2 (en) * | 2006-11-03 | 2014-12-30 | Salix Pharmaceuticals, Inc. | Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives |
| JP5180092B2 (ja) | 2005-11-22 | 2013-04-10 | オレキシジェン・セラピューティクス・インコーポレーテッド | インスリン感受性を増すための組成物および方法 |
| WO2007089318A2 (en) * | 2005-11-23 | 2007-08-09 | Orexigen Therapeutics, Inc. | Compositions and methods for reducing food cravings |
| EP1954316A1 (en) | 2005-11-28 | 2008-08-13 | Orexigen Therapeutics, Inc. | Methods of treating anxiety disorders |
| US8916195B2 (en) | 2006-06-05 | 2014-12-23 | Orexigen Therapeutics, Inc. | Sustained release formulation of naltrexone |
| ES2636657T3 (es) * | 2006-06-19 | 2017-10-06 | Alpharma Pharmaceuticals Llc | Composición farmacéutica |
| KR101264789B1 (ko) * | 2006-06-30 | 2013-05-15 | 엘지디스플레이 주식회사 | 횡전계 방식 액정표시장치용 어레이 기판과 그 제조방법 |
| CA2693992C (en) * | 2006-07-20 | 2017-01-31 | Somaxon Pharmaceuticals, Inc. | Methods of improving the pharmacokinetics of doxepin |
| CN101573103A (zh) | 2006-11-09 | 2009-11-04 | 奥雷西根治疗公司 | 用于施用重量减轻药物的单位剂量包装和方法 |
| AR063959A1 (es) * | 2006-11-09 | 2009-03-04 | Orexigen Therapeutics Inc | Formulaciones farmaceuticas en capas |
| DK3461503T3 (da) * | 2007-04-11 | 2022-02-14 | Biomarin Pharm Inc | Fremgangsmåder til indgivelse af tetrahydrobiopterin, associerede sammensætninger og målingsfremgangsmåder |
| DE102007036076A1 (de) | 2007-08-01 | 2009-02-05 | Bayer Healthcare Aktiengesellschaft | Dipeptoid-Produgs und ihre Verwendung |
| WO2009035473A2 (en) * | 2007-09-13 | 2009-03-19 | Sanfilippo Louis C | Method of treating binge eating disorder, obesity resulting from binge eating behavior and depressive disorders |
| US20110144145A1 (en) | 2008-05-30 | 2011-06-16 | Orexigen Therapeutics, Inc. | Methods for treating visceral fat conditions |
| PL3884947T3 (pl) * | 2010-12-03 | 2024-05-06 | Nalpropion Pharmaceuticals Llc | Wzrost biodostępności leku w terapii naltreksonem |
-
2011
- 2011-12-02 PL PL21152314.7T patent/PL3884947T3/pl unknown
- 2011-12-02 RS RS20170491A patent/RS56014B1/sr unknown
- 2011-12-02 MX MX2017013169A patent/MX384662B/es unknown
- 2011-12-02 PT PT171569858T patent/PT3222280T/pt unknown
- 2011-12-02 SM SM20210227T patent/SMT202100227T1/it unknown
- 2011-12-02 EP EP17156985.8A patent/EP3222280B1/en active Active
- 2011-12-02 DK DK21152314.7T patent/DK3884947T3/da active
- 2011-12-02 HU HUE21152314A patent/HUE065852T2/hu unknown
- 2011-12-02 WO PCT/US2011/063177 patent/WO2012075459A1/en not_active Ceased
- 2011-12-02 RS RS20240196A patent/RS65198B1/sr unknown
- 2011-12-02 SM SM20240038T patent/SMT202400038T1/it unknown
- 2011-12-02 ES ES17156985T patent/ES2866879T3/es active Active
- 2011-12-02 AR ARP110104512A patent/AR093182A1/es not_active Application Discontinuation
- 2011-12-02 EP EP23209711.3A patent/EP4349369B1/en active Active
- 2011-12-02 LT LTEP17156985.8T patent/LT3222280T/lt unknown
- 2011-12-02 US US13/991,137 patent/US20130245056A1/en not_active Abandoned
- 2011-12-02 FI FIEP21152314.7T patent/FI3884947T3/fi active
- 2011-12-02 DK DK17156985.8T patent/DK3222280T3/da active
- 2011-12-02 RU RU2013127423A patent/RU2640561C2/ru active
- 2011-12-02 HR HRP20170734TT patent/HRP20170734T1/hr unknown
- 2011-12-02 DK DK11845186.3T patent/DK2646031T3/en active
- 2011-12-02 KR KR1020217015625A patent/KR102391511B1/ko active Active
- 2011-12-02 EP EP11845186.3A patent/EP2646031B9/en active Active
- 2011-12-02 TW TW100144442A patent/TWI618536B/zh active
- 2011-12-02 KR KR1020137017317A patent/KR20140035320A/ko not_active Ceased
- 2011-12-02 HU HUE11845186A patent/HUE034393T2/en unknown
- 2011-12-02 SI SI201131967T patent/SI3222280T1/sl unknown
- 2011-12-02 ES ES11845186.3T patent/ES2625527T3/es active Active
- 2011-12-02 PT PT118451863T patent/PT2646031T/pt unknown
- 2011-12-02 CN CN2011800638854A patent/CN103313711A/zh active Pending
- 2011-12-02 PL PL11845186T patent/PL2646031T3/pl unknown
- 2011-12-02 CA CA2819262A patent/CA2819262C/en active Active
- 2011-12-02 RS RS20210469A patent/RS62149B1/sr unknown
- 2011-12-02 SI SI201132102T patent/SI3884947T1/sl unknown
- 2011-12-02 PT PT211523147T patent/PT3884947T/pt unknown
- 2011-12-02 HR HRP20240115TT patent/HRP20240115T1/hr unknown
- 2011-12-02 HU HUE17156985A patent/HUE053831T2/hu unknown
- 2011-12-02 LT LTEP21152314.7T patent/LT3884947T/lt unknown
- 2011-12-02 LT LTEP11845186.3T patent/LT2646031T/lt unknown
- 2011-12-02 CA CA3239386A patent/CA3239386A1/en active Pending
- 2011-12-02 EP EP21152314.7A patent/EP3884947B1/en active Active
- 2011-12-02 PL PL17156985T patent/PL3222280T3/pl unknown
- 2011-12-02 SM SM20170232T patent/SMT201700232T1/it unknown
- 2011-12-02 BR BR112013013390A patent/BR112013013390A2/pt not_active Application Discontinuation
- 2011-12-02 SI SI201131199A patent/SI2646031T1/sl unknown
- 2011-12-02 AU AU2011336304A patent/AU2011336304B2/en active Active
- 2011-12-02 MX MX2013006071A patent/MX356801B/es active IP Right Grant
- 2011-12-02 JP JP2013542229A patent/JP6008866B2/ja active Active
- 2011-12-02 KR KR1020187016354A patent/KR101984500B1/ko active Active
- 2011-12-02 KR KR1020207011510A patent/KR102258043B1/ko active Active
- 2011-12-02 KR KR1020197014576A patent/KR102105857B1/ko active Active
-
2013
- 2013-05-23 IL IL226504A patent/IL226504B/en active IP Right Grant
- 2013-05-31 CL CL2013001564A patent/CL2013001564A1/es unknown
-
2016
- 2016-09-12 JP JP2016177391A patent/JP6456890B2/ja active Active
-
2017
- 2017-05-18 CY CY20171100524T patent/CY1118968T1/el unknown
- 2017-06-26 AU AU2017204309A patent/AU2017204309A1/en not_active Abandoned
-
2018
- 2018-12-19 JP JP2018237245A patent/JP7025319B2/ja active Active
-
2019
- 2019-11-21 IL IL270841A patent/IL270841A/en unknown
-
2020
- 2020-12-21 IL IL279626A patent/IL279626A/en unknown
-
2021
- 2021-04-19 CY CY20211100340T patent/CY1124331T1/el unknown
- 2021-04-19 HR HRP20210618TT patent/HRP20210618T1/hr unknown
- 2021-12-23 AR ARP210103655A patent/AR124500A2/es unknown
-
2022
- 2022-02-10 JP JP2022019546A patent/JP2022060331A/ja active Pending
-
2024
- 2024-03-27 JP JP2024051334A patent/JP2024071605A/ja active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HRP20240115T1 (hr) | Povećavanje bioraspoloživosti lijeka u terapiji naltreksonom | |
| AU2023200826B2 (en) | Administration of berberine metabolites | |
| JP6280535B2 (ja) | Ｓ−アデノシルメチオニンおよび没食子酸エステルを含む組成物 | |
| JP2017506651A (ja) | 脂肪肝の低減または予防のための組成物および方法 | |
| JP2015503593A5 (enExample) | ||
| WO2008093848A1 (ja) | ホスファチジルコリンを含有する炎症マーカー低減組成物 | |
| JP2013544290A5 (enExample) | ||
| JP2013516493A5 (enExample) | ||
| JP2010138170A (ja) | 抗疲労組成物 | |
| WO2011019735A3 (en) | Nutritional supplements | |
| JP2020526485A5 (enExample) | ||
| RU2009145804A (ru) | Аксомадол для лечения боли от артроза | |
| RU2014146562A (ru) | Композиция, содержащая альфа-липоевую кислоту и гонокиол, для лечения нейропатий | |
| KR20190134671A (ko) | 체중을 감소시키고 체지방을 감소시키기 위한 조성물 및 그의 제약 생성물 및 적용 | |
| JP2017530142A5 (enExample) | ||
| JP2015507002A5 (enExample) | ||
| EP1949900A3 (en) | Controlled release solid formulation for oral administration as single dose sachet and method of preparation thereof | |
| JP2010090097A (ja) | 抗骨粗鬆症組成物 | |
| JP5734134B2 (ja) | 抗疲労用医薬組成物 | |
| WO2009108067A3 (en) | Fatty acid derivatives for use in the prevention and treatment of hsmi | |
| JP6143215B2 (ja) | 高脂肪食への嗜好性を軽減させるための医薬組成物、飲食品組成物または飲食品添加剤 | |
| TWI604840B (zh) | Fat loss weight loss composition | |
| CN117979971A (zh) | 基于1-甲基黄嘌呤的生物活性组合物及其使用方法 | |
| CN104540509A (zh) | 用于肝脏再生的药物组合物 | |
| JP2014172901A (ja) | 脂肪吸収抑制剤 |