JP2020526485A5 - - Google Patents
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- Publication number
- JP2020526485A5 JP2020526485A5 JP2019571280A JP2019571280A JP2020526485A5 JP 2020526485 A5 JP2020526485 A5 JP 2020526485A5 JP 2019571280 A JP2019571280 A JP 2019571280A JP 2019571280 A JP2019571280 A JP 2019571280A JP 2020526485 A5 JP2020526485 A5 JP 2020526485A5
- Authority
- JP
- Japan
- Prior art keywords
- substance according
- propionic acid
- butyric acid
- substance
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- FERIUCNNQQJTOY-UHFFFAOYSA-N Butyric acid Chemical compound CCCC(O)=O FERIUCNNQQJTOY-UHFFFAOYSA-N 0.000 claims description 30
- XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 claims description 30
- 239000000126 substance Substances 0.000 claims description 21
- 150000003839 salts Chemical class 0.000 claims description 19
- 235000019260 propionic acid Nutrition 0.000 claims description 15
- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 claims description 15
- 150000002148 esters Chemical class 0.000 claims description 12
- 235000015872 dietary supplement Nutrition 0.000 claims description 9
- 239000002775 capsule Substances 0.000 claims description 5
- 208000018737 Parkinson disease Diseases 0.000 claims description 4
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical group C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 3
- 159000000007 calcium salts Chemical class 0.000 claims description 3
- 230000002265 prevention Effects 0.000 claims description 3
- 239000011734 sodium Substances 0.000 claims description 3
- 229910052708 sodium Inorganic materials 0.000 claims description 3
- 230000003319 supportive effect Effects 0.000 claims description 3
- 239000003826 tablet Substances 0.000 claims description 3
- 238000011282 treatment Methods 0.000 claims description 3
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims description 2
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims description 2
- 239000004480 active ingredient Substances 0.000 claims description 2
- 125000004494 ethyl ester group Chemical group 0.000 claims description 2
- 239000011777 magnesium Substances 0.000 claims description 2
- 229910052749 magnesium Inorganic materials 0.000 claims description 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 2
- 239000011591 potassium Substances 0.000 claims description 2
- 229910052700 potassium Inorganic materials 0.000 claims description 2
- 239000000843 powder Substances 0.000 claims description 2
- 230000001225 therapeutic effect Effects 0.000 claims description 2
- 230000003449 preventive effect Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102017115819.7A DE102017115819A1 (de) | 2017-07-13 | 2017-07-13 | Mittel zur prophylaktischen und/oder unterstützenden therapeutischen Behandlung von Morbus Parkinson |
| DE102017115819.7 | 2017-07-13 | ||
| PCT/EP2018/069089 WO2019012108A1 (de) | 2017-07-13 | 2018-07-13 | Propion- und/oder buttersäure zur verwendung zur prophylaktischen und/oder unterstützenden therapeutischen behandlung von morbus parkinson |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020526485A JP2020526485A (ja) | 2020-08-31 |
| JP2020526485A5 true JP2020526485A5 (enExample) | 2021-02-04 |
| JP7206223B2 JP7206223B2 (ja) | 2023-01-17 |
Family
ID=63108510
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019571280A Active JP7206223B2 (ja) | 2017-07-13 | 2018-07-13 | パーキンソン病の予防および／または支持治療処置のための物質 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20200163914A1 (enExample) |
| EP (1) | EP3651754B1 (enExample) |
| JP (1) | JP7206223B2 (enExample) |
| KR (1) | KR20200027976A (enExample) |
| CN (1) | CN110996933A (enExample) |
| AU (2) | AU2018298862A1 (enExample) |
| BR (1) | BR112020000570A2 (enExample) |
| CA (1) | CA3067728A1 (enExample) |
| DE (1) | DE102017115819A1 (enExample) |
| WO (1) | WO2019012108A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021048440A1 (en) | 2019-09-13 | 2021-03-18 | Basf Se | Composition for the treatment of neurodegenerative diseases |
| CN111450238A (zh) * | 2020-03-31 | 2020-07-28 | 上海交通大学医学院附属瑞金医院 | 骨钙素或丙酸在制备抗帕金森病药物中的应用 |
| CN113332266A (zh) * | 2021-06-10 | 2021-09-03 | 徐州医科大学 | 含丁酸的治疗与预防神经退行性疾病的药物及丁酸的应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19503598A1 (de) * | 1995-02-03 | 1996-08-08 | Zuzana Dr Cully | Verfahren zur fermentativen Herstellung von Propionsäure oder Buttersäure bzw. deren Salze |
| NL1009990C2 (nl) * | 1998-09-02 | 2000-03-15 | Sibeco Chemicals | Voedingssupplement en werkwijze voor het vervaardigen van zulk voedingssupplement. |
| US20060105962A1 (en) * | 2004-11-14 | 2006-05-18 | Robinson Robert O A | Tonic to maintain intestinal flora |
| CN103415218A (zh) * | 2011-01-12 | 2013-11-27 | 阿尔贝特·达克瑟尔 | 饮料 |
| US9764019B2 (en) * | 2013-07-09 | 2017-09-19 | Vedanta Biosciences, Inc. | Compositions containing combinations of bioactive molecules derived from microbiota for treatment of disease |
| CN105055457A (zh) * | 2015-08-06 | 2015-11-18 | 温州医科大学附属第二医院 | 一种防治阿尔茨海默病的药物及其制备方法和应用 |
| DE102016103242A1 (de) * | 2016-02-24 | 2017-08-24 | Flexopharm Brain Gmbh & Co. Kg | Mittel zur unterstützenden Immunmodulation |
| ES2808928T3 (es) * | 2015-11-27 | 2021-03-02 | Birrbeheer B V | Sales de butirato para uso en enfermedades inflamatorias |
| US11065217B2 (en) * | 2017-01-27 | 2021-07-20 | Temple University—Of the Commonwealth System of Higher Education | Use of short chain fatty acids for the treatment and prevention of diseases and disorders |
-
2017
- 2017-07-13 DE DE102017115819.7A patent/DE102017115819A1/de not_active Withdrawn
-
2018
- 2018-07-13 JP JP2019571280A patent/JP7206223B2/ja active Active
- 2018-07-13 KR KR1020207003431A patent/KR20200027976A/ko not_active Ceased
- 2018-07-13 CN CN201880042374.6A patent/CN110996933A/zh active Pending
- 2018-07-13 US US16/627,688 patent/US20200163914A1/en not_active Abandoned
- 2018-07-13 BR BR112020000570-3A patent/BR112020000570A2/pt not_active Application Discontinuation
- 2018-07-13 WO PCT/EP2018/069089 patent/WO2019012108A1/de not_active Ceased
- 2018-07-13 EP EP18750103.6A patent/EP3651754B1/de active Active
- 2018-07-13 CA CA3067728A patent/CA3067728A1/en active Pending
- 2018-07-13 AU AU2018298862A patent/AU2018298862A1/en not_active Abandoned
-
2021
- 2021-11-26 AU AU2021273627A patent/AU2021273627B2/en active Active
-
2022
- 2022-06-20 US US17/807,797 patent/US20220313634A1/en not_active Abandoned
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