JP2016053065A5 - - Google Patents
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- Publication number
- JP2016053065A5 JP2016053065A5 JP2015217669A JP2015217669A JP2016053065A5 JP 2016053065 A5 JP2016053065 A5 JP 2016053065A5 JP 2015217669 A JP2015217669 A JP 2015217669A JP 2015217669 A JP2015217669 A JP 2015217669A JP 2016053065 A5 JP2016053065 A5 JP 2016053065A5
- Authority
- JP
- Japan
- Prior art keywords
- dha
- traumatic brain
- brain injury
- risk
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- MBMBGCFOFBJSGT-KUBAVDMBSA-N all-cis-docosa-4,7,10,13,16,19-hexaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC(O)=O MBMBGCFOFBJSGT-KUBAVDMBSA-N 0.000 claims 28
- 239000000203 mixture Substances 0.000 claims 26
- 208000030886 Traumatic Brain injury Diseases 0.000 claims 24
- 235000020669 docosahexaenoic acid Nutrition 0.000 claims 24
- 230000009529 traumatic brain injury Effects 0.000 claims 22
- 229940090949 docosahexaenoic acid Drugs 0.000 claims 14
- DVSZKTAMJJTWFG-SKCDLICFSA-N (2e,4e,6e,8e,10e,12e)-docosa-2,4,6,8,10,12-hexaenoic acid Chemical compound CCCCCCCCC\C=C\C=C\C=C\C=C\C=C\C=C\C(O)=O DVSZKTAMJJTWFG-SKCDLICFSA-N 0.000 claims 10
- GZJLLYHBALOKEX-UHFFFAOYSA-N 6-Ketone, O18-Me-Ussuriedine Natural products CC=CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O GZJLLYHBALOKEX-UHFFFAOYSA-N 0.000 claims 10
- JAZBEHYOTPTENJ-JLNKQSITSA-N all-cis-5,8,11,14,17-icosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 claims 10
- KAUVQQXNCKESLC-UHFFFAOYSA-N docosahexaenoic acid (DHA) Natural products COC(=O)C(C)NOCC1=CC=CC=C1 KAUVQQXNCKESLC-UHFFFAOYSA-N 0.000 claims 10
- 235000020673 eicosapentaenoic acid Nutrition 0.000 claims 10
- 229960005135 eicosapentaenoic acid Drugs 0.000 claims 10
- JAZBEHYOTPTENJ-UHFFFAOYSA-N eicosapentaenoic acid Natural products CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O JAZBEHYOTPTENJ-UHFFFAOYSA-N 0.000 claims 10
- 235000014113 dietary fatty acids Nutrition 0.000 claims 8
- 230000000694 effects Effects 0.000 claims 8
- 229930195729 fatty acid Natural products 0.000 claims 8
- 239000000194 fatty acid Substances 0.000 claims 8
- 150000004665 fatty acids Chemical class 0.000 claims 8
- 230000001575 pathological effect Effects 0.000 claims 6
- 239000002552 dosage form Substances 0.000 claims 4
- 210000004556 brain Anatomy 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 239000006186 oral dosage form Substances 0.000 claims 3
- 208000018652 Closed Head injury Diseases 0.000 claims 2
- 208000028361 Penetrating Head injury Diseases 0.000 claims 2
- 230000037396 body weight Effects 0.000 claims 2
- 125000005907 alkyl ester group Chemical class 0.000 claims 1
- 235000013361 beverage Nutrition 0.000 claims 1
- 230000009514 concussion Effects 0.000 claims 1
- 235000015872 dietary supplement Nutrition 0.000 claims 1
- 235000013305 food Nutrition 0.000 claims 1
- 230000000813 microbial effect Effects 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 238000001356 surgical procedure Methods 0.000 claims 1
- 150000003626 triacylglycerols Chemical class 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25123009P | 2009-10-13 | 2009-10-13 | |
| US61/251,230 | 2009-10-13 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012534338A Division JP2013507454A (ja) | 2009-10-13 | 2010-10-13 | 外傷性脳損傷の病理学的影響の危険を軽減する方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017174229A Division JP6544747B2 (ja) | 2009-10-13 | 2017-09-11 | 外傷性脳損傷の病理学的影響の危険を軽減する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016053065A JP2016053065A (ja) | 2016-04-14 |
| JP2016053065A5 true JP2016053065A5 (enExample) | 2016-06-02 |
| JP6516158B2 JP6516158B2 (ja) | 2019-05-22 |
Family
ID=43876523
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012534338A Pending JP2013507454A (ja) | 2009-10-13 | 2010-10-13 | 外傷性脳損傷の病理学的影響の危険を軽減する方法 |
| JP2015217669A Expired - Fee Related JP6516158B2 (ja) | 2009-10-13 | 2015-11-05 | 外傷性脳損傷の病理学的影響の危険を軽減する方法 |
| JP2017174229A Expired - Fee Related JP6544747B2 (ja) | 2009-10-13 | 2017-09-11 | 外傷性脳損傷の病理学的影響の危険を軽減する方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012534338A Pending JP2013507454A (ja) | 2009-10-13 | 2010-10-13 | 外傷性脳損傷の病理学的影響の危険を軽減する方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017174229A Expired - Fee Related JP6544747B2 (ja) | 2009-10-13 | 2017-09-11 | 外傷性脳損傷の病理学的影響の危険を軽減する方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20110257267A1 (enExample) |
| EP (1) | EP2488190B1 (enExample) |
| JP (3) | JP2013507454A (enExample) |
| AU (1) | AU2010306870B2 (enExample) |
| CA (1) | CA2777367A1 (enExample) |
| ES (1) | ES2643628T3 (enExample) |
| PL (1) | PL2488190T3 (enExample) |
| WO (1) | WO2011047095A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2488190B1 (en) | 2009-10-13 | 2017-09-20 | DSM IP Assets B.V. | Reducing the risk of pathological effects of traumatic brain injury |
| WO2012125020A1 (en) * | 2011-03-14 | 2012-09-20 | N.V. Nutricia | Method for treating neurotrauma |
| US9269046B2 (en) * | 2012-01-18 | 2016-02-23 | Brainscope Company, Inc. | Method and device for multimodal neurological evaluation |
| US8792974B2 (en) | 2012-01-18 | 2014-07-29 | Brainscope Company, Inc. | Method and device for multimodal neurological evaluation |
| CA3053187A1 (en) * | 2017-02-09 | 2018-08-16 | Bodhi Research & Development Inc. | Cannabinoid-containing fatty acid formulations for treating disorders of the nervous system |
| BR112020003841A2 (pt) * | 2017-08-25 | 2020-09-08 | Struct Nutrition, Llc | métodos para atenuar uma lesão cerebral relacionada a traumas em um indivíduo e o impacto de impactos repetidos na cabeça no cérebro, e, composição para atenuar lesões no cérebro relacionados a impactos repetidos na cabeça. |
| KR101946362B1 (ko) | 2017-10-27 | 2019-02-11 | 파이코일바이오텍코리아(주) | 뇌 염증성 질환 예방, 개선 또는 치료용 조성물 |
| CN111406110B (zh) * | 2017-11-17 | 2023-08-08 | 广西小藻农业科技有限公司 | 藻类多不饱和脂肪酸的制备 |
| CN112955562A (zh) | 2018-11-02 | 2021-06-11 | 玛拉可再生能源公司 | 具有改进的营养价值的海藻油 |
| CN114286680A (zh) | 2019-06-20 | 2022-04-05 | 阿克海洋生物南极股份公司 | 肠胃外溶血磷脂酰胆碱制剂诸如lpc-dha、lpc-epa及其在治疗中的用途 |
| NL2023407B1 (en) | 2019-06-28 | 2021-02-01 | Aker Biomarine Antarctic As | Parenteral lysophosphatidylcholine formulations |
| US20230398088A1 (en) * | 2020-10-30 | 2023-12-14 | The Trustees Of The University Of Pennsylvania | Lipid Prophylactic Brain Injury Treatment |
| FR3132430B1 (fr) * | 2022-02-09 | 2025-04-25 | Polaris | Composition comprenant un melange de dha et/ou d’epa et d’un phospholipide d’orgine vegetale |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5407957A (en) | 1990-02-13 | 1995-04-18 | Martek Corporation | Production of docosahexaenoic acid by dinoflagellates |
| US5506211A (en) * | 1994-05-09 | 1996-04-09 | The Uab Research Foundation | Genistein for use in inhibiting osteroclasts |
| US6681403B2 (en) * | 2000-03-13 | 2004-01-27 | Robert M. Lyden | Shin-guard, helmet, and articles of protective equipment including light cure material |
| US6469049B1 (en) * | 2000-04-21 | 2002-10-22 | The United States Of America As Represented By The Secretary Of The Army | Method of treating, preventing or inhibiting central nervous system injuries and diseases |
| EP1450787A4 (en) * | 2001-11-15 | 2006-01-25 | Galileo Pharmaceuticals Inc | FORMULATIONS AND METHODS FOR THE TREATMENT OR AMELIORATION OF INFLAMMATORY CONDITIONS |
| WO2005063296A2 (en) * | 2003-12-23 | 2005-07-14 | Pfizer Products Inc. | Therapeutic combination for cognition enhancement and psychotic disorders |
| US20050164908A1 (en) | 2004-01-23 | 2005-07-28 | Ginsberg Myron D. | Neuroprotective complex for treatment of cerebral ischemia and injury |
| US20060276373A1 (en) * | 2004-01-23 | 2006-12-07 | Bazan Nicolas G | Neuroprotective complex for treatment of cerebral ischemia and injury |
| US20060059605A1 (en) * | 2004-09-22 | 2006-03-23 | Xenith Athletics, Inc. | Layered construction of protective headgear with one or more compressible layers of thermoplastic elastomer material |
| JP5697293B2 (ja) | 2005-06-30 | 2015-04-08 | サントリーホールディングス株式会社 | 器質的脳障害に起因する高次脳機能の低下に対する改善作用を有する組成物 |
| CN101262863B (zh) * | 2005-07-08 | 2016-08-31 | Dsmip资产公司 | 用于治疗痴呆和前痴呆相关病症的多不饱和脂肪酸 |
| WO2007100892A2 (en) * | 2006-02-28 | 2007-09-07 | The Board Of Trustees Of The Leland Stanford Junior University | Trojan horse immunotherapy |
| CN101049297B (zh) * | 2006-04-06 | 2010-11-24 | 北京百慧生化制药有限责任公司 | 一种高dha型-乙酯和epa-乙酯的脂肪酸乙酯及其制造方法和制剂 |
| MX374545B (es) * | 2007-06-29 | 2025-03-06 | Dsm Ip Assets Bv | Produccion y purificacion de esteres de acidos grasos poliinsaturados. |
| WO2009057994A1 (en) * | 2007-11-02 | 2009-05-07 | N.V. Nutricia | Unit dosage for brain health |
| EP2488190B1 (en) | 2009-10-13 | 2017-09-20 | DSM IP Assets B.V. | Reducing the risk of pathological effects of traumatic brain injury |
| CN109350408B (zh) * | 2018-12-11 | 2024-06-14 | 陶国民 | 过床护理椅 |
-
2010
- 2010-10-13 EP EP10824055.7A patent/EP2488190B1/en active Active
- 2010-10-13 WO PCT/US2010/052564 patent/WO2011047095A1/en not_active Ceased
- 2010-10-13 PL PL10824055T patent/PL2488190T3/pl unknown
- 2010-10-13 US US12/904,049 patent/US20110257267A1/en not_active Abandoned
- 2010-10-13 ES ES10824055.7T patent/ES2643628T3/es active Active
- 2010-10-13 AU AU2010306870A patent/AU2010306870B2/en not_active Ceased
- 2010-10-13 JP JP2012534338A patent/JP2013507454A/ja active Pending
- 2010-10-13 CA CA2777367A patent/CA2777367A1/en not_active Abandoned
-
2015
- 2015-11-05 JP JP2015217669A patent/JP6516158B2/ja not_active Expired - Fee Related
-
2017
- 2017-09-11 JP JP2017174229A patent/JP6544747B2/ja not_active Expired - Fee Related
-
2018
- 2018-10-15 US US16/160,388 patent/US11413263B2/en active Active
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