RU2020101477A - Фармацевтические композиции, содержащие дглк, и их применение - Google Patents

Фармацевтические композиции, содержащие дглк, и их применение Download PDF

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RU2020101477A
RU2020101477A RU2020101477A RU2020101477A RU2020101477A RU 2020101477 A RU2020101477 A RU 2020101477A RU 2020101477 A RU2020101477 A RU 2020101477A RU 2020101477 A RU2020101477 A RU 2020101477A RU 2020101477 A RU2020101477 A RU 2020101477A
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pharmaceutical composition
acid
composition according
dihomogamma
linolenic acid
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RU2020101477A
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Мехар МАНКУ
Дэвид КОГЛЭН
Джон КЛАЙМАКС
Джеймс ДАНН
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Дигнити Сайенсиз Лимитед
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Publication of RU2020101477A publication Critical patent/RU2020101477A/ru

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    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
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    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
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Claims (9)

1. Фармацевтическая композиция для применения при лечении пациента, страдающего кожным заболеванием, где фармацевтическая композиция содержит дигомогамма-линоленовую кислоту, эйкозатетраеновую кислоту, эйкозатриеновую кислоту, олеиновую кислоту, линолевую кислоту и эйкозадиеновую кислоту, инкапсулированную в оболочке капсулы и, где фармацевтическая композиция содержит, по меньшей мере, около 80% дигомогамма-линоленовой кислоты от общей массы жирных кислот.
2. Фармацевтическая композиция по п.1, где пациенту, страдающему кожным заболеванием, вводят фармацевтическую композицию в состоянии натощак.
3. Фармацевтическая композиция по п.2, где состояние натощак означает отсутствие пищи до введения фармацевтической композиции.
4. Фармацевтическая композиция по п.1, где оболочка капсулы содержит желатин и глицерин.
5. Фармацевтическая композиция по п.1, где в оболочку капсулы заключено до 1 г дигомогамма-линоленовой кислоты.
6. Фармацевтическая композиция по п.1, где от приблизительно 200 мг до приблизительно 1 г дигомогамма-линоленовой кислоты инкапсулировано в оболочку капсулы.
7. фармацевтическая композиция по п.1, где оболочка капсулы содержит обработанный известью костный желатин и оболочка капсулы дополнительно содержит один или несколько из: глицерина, очищенной воды, диоксида титана, триглицеридов со средней длиной цепи и/или лецитина.
8. Фармацевтическая композиция по п.1, содержащая от приблизительно 200 мг до приблизительно 1 г дигомогамма-линоленовой кислоты и, где композиция содержит не более 5% любой отдельной жирной кислоты, отличной от дигомогамма-линоленовой кислоты от общей массы жирных кислот.
9. Фармацевтическая композиция по любому из предыдущих пунктов, где фармацевтическая композиция вводится в количестве от 1 до 8 капсул в день.
RU2020101477A 2014-06-04 2015-06-04 Фармацевтические композиции, содержащие дглк, и их применение RU2020101477A (ru)

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US201462007752P 2014-06-04 2014-06-04
US62/007,752 2014-06-04
US201462058469P 2014-10-01 2014-10-01
US62/058,469 2014-10-01

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