CN110996933A - 用于帕金森病的预防性和/或支持性治疗处理的药剂 - Google Patents

用于帕金森病的预防性和/或支持性治疗处理的药剂 Download PDF

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Publication number
CN110996933A
CN110996933A CN201880042374.6A CN201880042374A CN110996933A CN 110996933 A CN110996933 A CN 110996933A CN 201880042374 A CN201880042374 A CN 201880042374A CN 110996933 A CN110996933 A CN 110996933A
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CN
China
Prior art keywords
medicament
disease
parkinson
salts
butyric acid
Prior art date
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Pending
Application number
CN201880042374.6A
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English (en)
Chinese (zh)
Inventor
H·普兹内泰克
A·哈希基亚
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Individual
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Individual
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Filing date
Publication date
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Publication of CN110996933A publication Critical patent/CN110996933A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12—Fatty acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00—Function of food ingredients
    • A23V2200/30—Foods, ingredients or supplements having a functional effect on health
    • A23V2200/322—Foods, ingredients or supplements having a functional effect on health having an effect on the health of the nervous system or on mental function
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2250/00—Food ingredients
    • A23V2250/02—Acid
    • A23V2250/05—Propionic acid

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
CN201880042374.6A 2017-07-13 2018-07-13 用于帕金森病的预防性和/或支持性治疗处理的药剂 Pending CN110996933A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102017115819.7A DE102017115819A1 (de) 2017-07-13 2017-07-13 Mittel zur prophylaktischen und/oder unterstützenden therapeutischen Behandlung von Morbus Parkinson
DE102017115819.7 2017-07-13
PCT/EP2018/069089 WO2019012108A1 (de) 2017-07-13 2018-07-13 Propion- und/oder buttersäure zur verwendung zur prophylaktischen und/oder unterstützenden therapeutischen behandlung von morbus parkinson

Publications (1)

Publication Number Publication Date
CN110996933A true CN110996933A (zh) 2020-04-10

Family

ID=63108510

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201880042374.6A Pending CN110996933A (zh) 2017-07-13 2018-07-13 用于帕金森病的预防性和/或支持性治疗处理的药剂

Country Status (10)

Country Link
US (2) US20200163914A1 (enExample)
EP (1) EP3651754B1 (enExample)
JP (1) JP7206223B2 (enExample)
KR (1) KR20200027976A (enExample)
CN (1) CN110996933A (enExample)
AU (2) AU2018298862A1 (enExample)
BR (1) BR112020000570A2 (enExample)
CA (1) CA3067728A1 (enExample)
DE (1) DE102017115819A1 (enExample)
WO (1) WO2019012108A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113332266A (zh) * 2021-06-10 2021-09-03 徐州医科大学 含丁酸的治疗与预防神经退行性疾病的药物及丁酸的应用

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021048440A1 (en) 2019-09-13 2021-03-18 Basf Se Composition for the treatment of neurodegenerative diseases
CN111450238A (zh) * 2020-03-31 2020-07-28 上海交通大学医学院附属瑞金医院 骨钙素或丙酸在制备抗帕金森病药物中的应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103415218A (zh) * 2011-01-12 2013-11-27 阿尔贝特·达克瑟尔 饮料
CN105055457A (zh) * 2015-08-06 2015-11-18 温州医科大学附属第二医院 一种防治阿尔茨海默病的药物及其制备方法和应用
JP2016530239A (ja) * 2013-07-09 2016-09-29 ピュアテック ベンチャーズ、エルエルシー 微生物叢由来生物活性分子の組み合わせを含む疾患治療用組成物
WO2017091072A1 (en) * 2015-11-27 2017-06-01 Birrbeheer B.V. Butyrate salts for use in inflammatory diseases

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19503598A1 (de) * 1995-02-03 1996-08-08 Zuzana Dr Cully Verfahren zur fermentativen Herstellung von Propionsäure oder Buttersäure bzw. deren Salze
NL1009990C2 (nl) * 1998-09-02 2000-03-15 Sibeco Chemicals Voedingssupplement en werkwijze voor het vervaardigen van zulk voedingssupplement.
US20060105962A1 (en) * 2004-11-14 2006-05-18 Robinson Robert O A Tonic to maintain intestinal flora
DE102016103242A1 (de) * 2016-02-24 2017-08-24 Flexopharm Brain Gmbh & Co. Kg Mittel zur unterstützenden Immunmodulation
CN110475551A (zh) * 2017-01-27 2019-11-19 英联邦高等教育系统天普大学 使用短链脂肪酸治疗和预防疾病和障碍

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103415218A (zh) * 2011-01-12 2013-11-27 阿尔贝特·达克瑟尔 饮料
JP2016530239A (ja) * 2013-07-09 2016-09-29 ピュアテック ベンチャーズ、エルエルシー 微生物叢由来生物活性分子の組み合わせを含む疾患治療用組成物
CN105055457A (zh) * 2015-08-06 2015-11-18 温州医科大学附属第二医院 一种防治阿尔茨海默病的药物及其制备方法和应用
WO2017091072A1 (en) * 2015-11-27 2017-06-01 Birrbeheer B.V. Butyrate salts for use in inflammatory diseases

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ENIE LEI 等: "Fatty acids and their therapeutic potential in neurological disorders", 《NEUROCHEMISTRY INTERNATIONAL》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113332266A (zh) * 2021-06-10 2021-09-03 徐州医科大学 含丁酸的治疗与预防神经退行性疾病的药物及丁酸的应用

Also Published As

Publication number Publication date
AU2021273627A1 (en) 2021-12-16
DE102017115819A1 (de) 2019-01-17
WO2019012108A1 (de) 2019-01-17
JP2020526485A (ja) 2020-08-31
EP3651754C0 (de) 2025-04-30
US20220313634A1 (en) 2022-10-06
EP3651754B1 (de) 2025-04-30
EP3651754A1 (de) 2020-05-20
BR112020000570A2 (pt) 2020-07-14
KR20200027976A (ko) 2020-03-13
JP7206223B2 (ja) 2023-01-17
AU2018298862A1 (en) 2020-01-23
CA3067728A1 (en) 2019-01-17
AU2021273627B2 (en) 2024-01-25
US20200163914A1 (en) 2020-05-28

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Application publication date: 20200410