HRP20220482T1 - Postupci in vitro diferencijacije neurona dopamina srednjeg mozga (mda) - Google Patents

Postupci in vitro diferencijacije neurona dopamina srednjeg mozga (mda) Download PDF

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Publication number
HRP20220482T1
HRP20220482T1 HRP20220482TT HRP20220482T HRP20220482T1 HR P20220482 T1 HRP20220482 T1 HR P20220482T1 HR P20220482T T HRP20220482T T HR P20220482TT HR P20220482 T HRP20220482 T HR P20220482T HR P20220482 T1 HRP20220482 T1 HR P20220482T1
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Croatia
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cells
signaling
days
activator
stem cells
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HRP20220482TT
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English (en)
Croatian (hr)
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Lorenz Studer
Stefan Irion
Mark Tomishima
Sonja KRIKS
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Memorial Sloan Kettering Cancer Center
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0619—Neurons
    • A—HUMAN NECESSITIES
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    • A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
    • A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
    • A—HUMAN NECESSITIES
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    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/13—Nerve growth factor [NGF]; Brain-derived neurotrophic factor [BDNF]; Cilliary neurotrophic factor [CNTF]; Glial-derived neurotrophic factor [GDNF]; Neurotrophins [NT]; Neuregulins
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/16—Activin; Inhibin; Mullerian inhibiting substance
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40—Regulators of development
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
    • C12N2501/72—Transferases [EC 2.]
    • C12N2501/727—Kinases (EC 2.7.)
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells

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  • Health & Medical Sciences (AREA)
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  • Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Developmental Biology & Embryology (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
HRP20220482TT 2015-06-01 2016-06-01 Postupci in vitro diferencijacije neurona dopamina srednjeg mozga (mda) HRP20220482T1 (hr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562169444P 2015-06-01 2015-06-01
US201562169379P 2015-06-01 2015-06-01
PCT/US2016/035312 WO2016196661A1 (en) 2015-06-01 2016-06-01 Methods of in vitro differentiation of midbrain dopamine (mda) neurons
EP16804350.3A EP3303564B1 (en) 2015-06-01 2016-06-01 Methods of in vitro differentiation of midbrain dopamine (mda) neurons

Publications (1)

Publication Number Publication Date
HRP20220482T1 true HRP20220482T1 (hr) 2022-07-08

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HRP20220482TT HRP20220482T1 (hr) 2015-06-01 2016-06-01 Postupci in vitro diferencijacije neurona dopamina srednjeg mozga (mda)

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US (3) US10858625B2 (https=)
EP (3) EP4070803B1 (https=)
JP (5) JP6974180B2 (https=)
KR (4) KR102358878B1 (https=)
AU (3) AU2016270793B2 (https=)
CY (1) CY1125423T1 (https=)
DK (2) DK4070803T3 (https=)
ES (2) ES2910032T3 (https=)
HR (1) HRP20220482T1 (https=)
HU (1) HUE058258T2 (https=)
IL (4) IL291532B2 (https=)
LT (1) LT3303564T (https=)
PL (1) PL3303564T3 (https=)
PT (2) PT3303564T (https=)
RS (1) RS63157B1 (https=)
SI (1) SI3303564T1 (https=)
SM (1) SMT202200263T1 (https=)
WO (1) WO2016196661A1 (https=)

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KR102625865B1 (ko) * 2016-08-16 2024-01-16 후지필름 셀룰러 다이내믹스, 인코포레이티드 만능 세포를 분화시키는 방법
KR20190141218A (ko) * 2017-04-26 2019-12-23 메모리얼 슬로안 케터링 캔서 센터 사용 준비된 냉동보존 세포
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JP2018522538A (ja) 2018-08-16
DK3303564T3 (da) 2022-04-04
EP3303564B1 (en) 2022-02-23
KR20240101884A (ko) 2024-07-02
KR102679619B1 (ko) 2024-07-01
IL291532B2 (en) 2024-12-01
JP2023181494A (ja) 2023-12-21
AU2022228216B2 (en) 2026-02-19
JP2020146060A (ja) 2020-09-17
IL291532A (en) 2022-05-01
SI3303564T1 (sl) 2022-07-29
IL313799A (en) 2024-08-01
IL320440A (en) 2025-06-01
PL3303564T3 (pl) 2022-05-09
AU2016270793A1 (en) 2017-12-14
PT4070803T (pt) 2026-01-08
EP4070803A1 (en) 2022-10-12
DK4070803T3 (da) 2026-01-12
AU2026200680A1 (en) 2026-02-19
JP2026015509A (ja) 2026-01-29
CY1125423T1 (el) 2024-12-13
WO2016196661A1 (en) 2016-12-08
EP4070803B1 (en) 2025-10-08
EP4079314A1 (en) 2022-10-26
KR102841407B1 (ko) 2025-08-01
SMT202200263T1 (it) 2022-07-21
US20240400987A1 (en) 2024-12-05
AU2016270793B2 (en) 2022-06-09
IL291532B1 (en) 2024-08-01
PT3303564T (pt) 2022-06-02
ES3057638T3 (en) 2026-03-03
IL255992A (en) 2018-01-31
IL255992B (en) 2022-04-01
KR20250118858A (ko) 2025-08-06
JP7737787B2 (ja) 2025-09-11
IL313799B1 (en) 2025-05-01
AU2022228216A1 (en) 2022-10-06
EP3303564A1 (en) 2018-04-11
JP6974180B2 (ja) 2021-12-01
HUE058258T2 (hu) 2022-07-28
JP2022031961A (ja) 2022-02-22
US20180094242A1 (en) 2018-04-05
IL313799B2 (en) 2025-09-01
ES2910032T3 (es) 2022-05-11
EP4079314B1 (en) 2025-10-29
KR20220020416A (ko) 2022-02-18
LT3303564T (lt) 2022-05-10
EP3303564A4 (en) 2018-10-31
RS63157B1 (sr) 2022-05-31
CA2987617A1 (en) 2016-12-08
KR102358878B1 (ko) 2022-02-08
KR20180014743A (ko) 2018-02-09
US10858625B2 (en) 2020-12-08
US12084679B2 (en) 2024-09-10
US20210123018A1 (en) 2021-04-29

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