DK3303564T3 - Fremgangsmåder til in vitro-differentiering af midthjerne-dopamin-(mda)-neuroner - Google Patents

Fremgangsmåder til in vitro-differentiering af midthjerne-dopamin-(mda)-neuroner Download PDF

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Publication number
DK3303564T3
DK3303564T3 DK16804350.3T DK16804350T DK3303564T3 DK 3303564 T3 DK3303564 T3 DK 3303564T3 DK 16804350 T DK16804350 T DK 16804350T DK 3303564 T3 DK3303564 T3 DK 3303564T3
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mda
neurons
procedures
vitro differentiation
brain dopamine
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DK16804350.3T
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Lorenz Studer
Stefan Irion
Mark Tomishima
Sonja Kriks
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Memorial Sloan Kettering Cancer Center
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0619—Neurons
    • A—HUMAN NECESSITIES
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK16804350.3T 2015-06-01 2016-06-01 Fremgangsmåder til in vitro-differentiering af midthjerne-dopamin-(mda)-neuroner DK3303564T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562169379P 2015-06-01 2015-06-01
US201562169444P 2015-06-01 2015-06-01
PCT/US2016/035312 WO2016196661A1 (en) 2015-06-01 2016-06-01 Methods of in vitro differentiation of midbrain dopamine (mda) neurons

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DK3303564T3 true DK3303564T3 (da) 2022-04-04

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US (2) US10858625B2 (da)
EP (3) EP4070803A1 (da)
JP (4) JP6974180B2 (da)
KR (2) KR102358878B1 (da)
AU (2) AU2016270793B2 (da)
CA (1) CA2987617A1 (da)
DK (1) DK3303564T3 (da)
ES (1) ES2910032T3 (da)
HR (1) HRP20220482T1 (da)
HU (1) HUE058258T2 (da)
IL (2) IL255992B (da)
LT (1) LT3303564T (da)
PL (1) PL3303564T3 (da)
PT (1) PT3303564T (da)
RS (1) RS63157B1 (da)
SI (1) SI3303564T1 (da)
WO (1) WO2016196661A1 (da)

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JP2019503703A (ja) * 2016-02-05 2019-02-14 メモリアル スローン ケタリング キャンサー センター 幹細胞由来外胚葉系統前駆体を分化する方法
CN117467608A (zh) * 2016-08-16 2024-01-30 富士胶片细胞动力股份有限公司 分化多能细胞的方法
KR20190141218A (ko) * 2017-04-26 2019-12-23 메모리얼 슬로안 케터링 캔서 센터 사용 준비된 냉동보존 세포
WO2019016113A1 (en) * 2017-07-17 2019-01-24 Miltenyi Biotec Gmbh METHOD FOR PROFILING EXPRESSION OF UNICELLULAR PROTEIN FROM DOPAMINERGIC PROGENITOR CELLS OF MESENCEPHALIC FLOOR
US20200248139A1 (en) * 2017-08-08 2020-08-06 Regents Of The University Of Minnesota Methods for generating and using organoids and cells thereof
JP2022534693A (ja) * 2019-05-23 2022-08-03 ザ マクリーン ホスピタル コーポレーション パーキンソン病のための自家細胞置換療法
US20220254448A1 (en) 2019-07-25 2022-08-11 The Scripps Research Institute Methods of identifying dopaminergic neurons and progenitor cells
MX2022002532A (es) * 2019-08-29 2022-06-16 Memorial Sloan Kettering Cancer Center Métodos para generar y aislar neuronas de dopamina del mesencéfalo.
CA3155277A1 (en) * 2019-09-20 2021-03-25 Korea Research Institute Of Bioscience And Biotechnology Production method for induced dopaminergic neuronal progenitors, using direct reprogramming
TW202202155A (zh) 2020-03-25 2022-01-16 美商薩那生物科技公司 用於治療神經病症及病況之低免疫原性神經細胞
WO2021216623A1 (en) 2020-04-21 2021-10-28 Aspen Neuroscience, Inc. Gene editing of lrrk2 in stem cells and method of use of cells differentiated therefrom
WO2021216622A1 (en) 2020-04-21 2021-10-28 Aspen Neuroscience, Inc. Gene editing of gba1 in stem cells and method of use of cells differentiated therefrom
CN116635047A (zh) * 2020-06-26 2023-08-22 米纳瓦生物技术公司 用于从多能干细胞衍生多巴胺能神经元的方法
WO2021263241A1 (en) * 2020-06-26 2021-12-30 Minerva Biotechnologies Corporation Methods for deriving dopaminergic neurons from pluripotent stem cells
CA3213988A1 (en) * 2021-04-07 2022-10-13 Christopher MCMAHON Dopaminergic precursor cells and methods of use
WO2023004370A1 (en) 2021-07-21 2023-01-26 Aspen Neuroscience, Inc. Aav-based modulation of gba1 and related compositions and uses thereof
US20230081881A1 (en) 2021-07-21 2023-03-16 Aspen Neuroscience, Inc. Transposon-based modulation of gba1 and related compositions and uses thereof
AU2022387671A1 (en) 2021-11-12 2024-05-16 Axent Biosciences Inc. Methods for production of functional neurons
WO2023201361A1 (en) 2022-04-15 2023-10-19 Aspen Neuroscience, Inc. Methods of classifying the differentiation state of cells and related compositions of differentiated cells

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Publication number Publication date
AU2016270793B2 (en) 2022-06-09
AU2016270793A1 (en) 2017-12-14
JP2020146060A (ja) 2020-09-17
US20210123018A1 (en) 2021-04-29
PL3303564T3 (pl) 2022-05-09
ES2910032T3 (es) 2022-05-11
SI3303564T1 (sl) 2022-07-29
CA2987617A1 (en) 2016-12-08
JP2023181494A (ja) 2023-12-21
AU2022228216A1 (en) 2022-10-06
IL255992B (en) 2022-04-01
HRP20220482T1 (hr) 2022-07-08
EP4079314A1 (en) 2022-10-26
KR20220020416A (ko) 2022-02-18
JP2022031961A (ja) 2022-02-22
EP3303564A1 (en) 2018-04-11
RS63157B1 (sr) 2022-05-31
EP4070803A1 (en) 2022-10-12
PT3303564T (pt) 2022-06-02
IL291532A (en) 2022-05-01
IL255992A (en) 2018-01-31
KR20180014743A (ko) 2018-02-09
US20180094242A1 (en) 2018-04-05
JP6974180B2 (ja) 2021-12-01
EP3303564A4 (en) 2018-10-31
US10858625B2 (en) 2020-12-08
WO2016196661A1 (en) 2016-12-08
EP3303564B1 (en) 2022-02-23
LT3303564T (lt) 2022-05-10
KR102358878B1 (ko) 2022-02-08
HUE058258T2 (hu) 2022-07-28
JP2018522538A (ja) 2018-08-16

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