DK3104814T3 - Apparat til suprachoroidal indgivelse af terapeutisk middel - Google Patents

Apparat til suprachoroidal indgivelse af terapeutisk middel Download PDF

Info

Publication number
DK3104814T3
DK3104814T3 DK15708368.4T DK15708368T DK3104814T3 DK 3104814 T3 DK3104814 T3 DK 3104814T3 DK 15708368 T DK15708368 T DK 15708368T DK 3104814 T3 DK3104814 T3 DK 3104814T3
Authority
DK
Denmark
Prior art keywords
therapevice
suprachoroidal administration
suprachoroidal
administration
Prior art date
Application number
DK15708368.4T
Other languages
English (en)
Inventor
Brendan J Oberkircher
Daniel W Price
Michael F Keane
Saeed Sokhanvar
Daniel J Yasevac
Michel G Bruehwiler
Leah R Soffer
Isaac J Khan
Benjamin L Ko
Christopher D Riemann
Nathan D Grubbs
Original Assignee
Gyroscope Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gyroscope Therapeutics Ltd filed Critical Gyroscope Therapeutics Ltd
Application granted granted Critical
Publication of DK3104814T3 publication Critical patent/DK3104814T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • A61M2005/1585—Needle inserters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0612—Eyes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
DK15708368.4T 2014-02-12 2015-02-11 Apparat til suprachoroidal indgivelse af terapeutisk middel DK3104814T3 (da)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201461938956P 2014-02-12 2014-02-12
US201462049100P 2014-09-11 2014-09-11
US201462049056P 2014-09-11 2014-09-11
US201462049089P 2014-09-11 2014-09-11
US201462049128P 2014-09-11 2014-09-11
US201562104295P 2015-01-16 2015-01-16
PCT/US2015/015362 WO2015126694A1 (en) 2014-02-12 2015-02-11 Method and apparatus for suprachoroidal administration of therapeutic agent

Publications (1)

Publication Number Publication Date
DK3104814T3 true DK3104814T3 (da) 2021-05-31

Family

ID=53773957

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15708368.4T DK3104814T3 (da) 2014-02-12 2015-02-11 Apparat til suprachoroidal indgivelse af terapeutisk middel

Country Status (10)

Country Link
US (3) US10226379B2 (da)
EP (2) EP3797742A1 (da)
JP (4) JP6548229B2 (da)
CN (3) CN113855385A (da)
BR (2) BR122020011529B1 (da)
DK (1) DK3104814T3 (da)
ES (1) ES2871138T3 (da)
PL (1) PL3104814T3 (da)
PT (1) PT3104814T (da)
WO (1) WO2015126694A1 (da)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070202186A1 (en) 2006-02-22 2007-08-30 Iscience Interventional Corporation Apparatus and formulations for suprachoroidal drug delivery
BR112013009205A2 (pt) * 2010-10-15 2016-07-26 Iscience Interventional Corp dispositivo para colocação na esclera de um olho, método para acessar o espaço supracoroidal de um olho, para acessar o espaço subretinal de um olho e para colocar um orifício dentro de um trato escleral em um olho.
CA3121759C (en) 2013-05-03 2024-01-02 Clearside Biomedical, Inc. Apparatus and methods for ocular injection
WO2015126694A1 (en) * 2014-02-12 2015-08-27 Ethicon Endo-Surgery, Inc. Method and apparatus for suprachoroidal administration of therapeutic agent
US9925088B2 (en) * 2014-06-06 2018-03-27 Janssen Biotech, Inc. Sub-retinal tangential needle catheter guide and introducer
US9949874B2 (en) 2014-06-06 2018-04-24 Janssen Biotech, Inc. Therapeutic agent delivery device with convergent lumen
US10322028B2 (en) 2014-09-11 2019-06-18 Orbit Biomedical Limited Method and apparatus for sensing position between layers of an eye
US10064752B2 (en) * 2014-09-11 2018-09-04 Orbit Biomedical Limited Motorized suprachoroidal injection of therapeutic agent
US10219936B2 (en) 2014-09-11 2019-03-05 Orbit Biomedical Limited Therapeutic agent delivery device with advanceable cannula and needle
US10258502B2 (en) 2014-09-18 2019-04-16 Orbit Biomedical Limited Therapeutic agent delivery device
WO2017005277A1 (en) * 2015-07-03 2017-01-12 Ophthorobotics Ag Intraocular injection system and methods for controlling such a system
GB2543645B (en) 2015-09-17 2019-01-02 Oxular Ltd Ophthalmic Injection device
US11357912B2 (en) * 2016-01-19 2022-06-14 Unomedical A/S Cannula and infusion devices
US10478553B2 (en) 2016-03-09 2019-11-19 Orbit Biomedical Limited Apparatus for subretinal administration of therapeutic agent via a curved needle
KR102381775B1 (ko) * 2016-03-16 2022-04-04 옥슬러 리미티드 안과용 전달 장치 및 안과용 약물 조성물
CA3062845A1 (en) 2016-05-02 2017-11-09 Clearside Biomedical, Inc. Systems and methods for ocular drug delivery
US11000410B2 (en) 2016-06-17 2021-05-11 Gyroscope Therapeutics Limited Guide apparatus for tangential entry into suprachoroidal space
US10646374B2 (en) 2016-06-17 2020-05-12 Orbit Biomedical Limited Apparatus and method to form entry bleb for subretinal delivery of therapeutic agent
US10806629B2 (en) 2016-06-17 2020-10-20 Gyroscope Therapeutics Limited Injection device for subretinal delivery of therapeutic agent
CA3072847A1 (en) 2016-08-12 2018-02-15 Clearside Biomedical, Inc. Devices and methods for adjusting the insertion depth of a needle for medicament delivery
CA3036993A1 (en) * 2016-09-02 2018-03-08 Aerie Pharmaceuticals, Inc. Implant applicators
US20190216645A1 (en) * 2016-09-23 2019-07-18 The Regents Of The University Of California Surgical device for ab-externo sub-retinal fluid drainage
US20180092772A1 (en) * 2016-10-04 2018-04-05 Firas Emad Mosalam Automated Eye Drop Dispenser
EP3554401A4 (en) 2016-12-19 2020-08-19 New World Medical, Inc. EYE TREATMENT DEVICES AND ASSOCIATED PROCEDURES FOR USE
US11273072B2 (en) * 2017-01-13 2022-03-15 Gyroscope Therapeutics Limited Suprachoroidal injection device
BR112019017027A2 (pt) * 2017-02-16 2020-04-14 Neomedix Corp dispositivos, sistemas e métodos para cirurgia de glaucoma minimamente invasiva
US11076984B2 (en) 2017-03-13 2021-08-03 Gyroscope Therapeutics Limited Method of performing subretinal drainage and agent delivery
US11033427B2 (en) 2017-04-13 2021-06-15 Alcon Inc. Vitreoretinal instruments for fluid aspiration
WO2018231150A1 (en) * 2017-06-15 2018-12-20 Singapore National Eye Centre Pte Ltd Eye drop guide device for instilling eye drops
US11576816B2 (en) * 2017-10-18 2023-02-14 Jesus Moreno Opthalmic microsurgical instrument
CN112165923B (zh) * 2018-04-19 2023-07-21 埃弗拉兹疗法有限公司 用于将物质注射到身体组织或器官的夹层中的装置
US11338113B2 (en) * 2018-06-07 2022-05-24 Becton, Dickinson And Company Needle position indicator
US11351354B2 (en) 2019-02-20 2022-06-07 Becton, Dickinson And Company Extension tube clamp providing positive displacement
US11759355B1 (en) 2019-02-26 2023-09-19 Gyroscope Therapeutics Limited Method of delivering leading blebs and agent to subretinal space
USD974561S1 (en) 2019-05-17 2023-01-03 Boston Scientific Scimed Inc. Radial ultrasound needle biopsy device
US20200375844A1 (en) * 2019-05-29 2020-12-03 Alcon Inc. Retina massage and smoothing device
CA3155564A1 (en) 2019-10-11 2021-04-15 Gyroscope Therapeutics Limited Dose clip assembly for syringe
WO2021234930A1 (ja) * 2020-05-21 2021-11-25 リバーフィールド株式会社 術具退避機構
WO2022115808A1 (en) * 2020-11-30 2022-06-02 Visionaire Products, Inc. Needle and collection device for ocular biopsy and methods of use
US20230390111A1 (en) 2020-12-22 2023-12-07 Gyroscope Therapeutics Limited Ocular cannula guide
JP2024505605A (ja) 2021-02-09 2024-02-07 ジャイロスコープ・セラピューティクス・リミテッド 脈絡膜上注射デバイス
KR102460395B1 (ko) * 2022-06-23 2022-10-27 이성헌 코 성형 또는 얼굴 리프팅용 리프팅 실의 삽입 장치
WO2024013559A1 (en) 2022-07-11 2024-01-18 Gyroscope Therapeutics Limited Transvitreal subretinal injector
WO2024052733A1 (en) 2022-09-06 2024-03-14 Gyroscope Therapeutics Limited Apparatus for subretinal administration of therapeutic agent via dual-curved needle

Family Cites Families (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2760483A (en) * 1953-10-29 1956-08-28 Tassicker Graham Edward Retinal stimulator
US5273530A (en) 1990-11-14 1993-12-28 The University Of Rochester Intraretinal delivery and withdrawal instruments
US5653715A (en) * 1993-03-09 1997-08-05 Chiron Vision Corporation Apparatus for preparing an intraocular lens for insertion
US5964740A (en) 1996-07-09 1999-10-12 Asahi Kogaku Kogyo Kabushiki Kaisha Treatment accessory for an endoscope
US6283951B1 (en) * 1996-10-11 2001-09-04 Transvascular, Inc. Systems and methods for delivering drugs to selected locations within the body
DE69633411T2 (de) 1995-10-13 2005-10-20 Transvascular, Inc., Menlo Park Verfahren und vorrichtung zur umgehung von arteriellen verengungen und/oder zur ausführung anderer transvaskularer eingriffe
DE19741487C2 (de) 1997-09-19 2000-08-31 Univ Eberhard Karls Vorrichtung für einen Zugang in den Subretinalraum eines Auges
US6309374B1 (en) * 1998-08-03 2001-10-30 Insite Vision Incorporated Injection apparatus and method of using same
US6143004A (en) * 1998-08-18 2000-11-07 Atrion Medical Products, Inc. Suturing device
US6162197A (en) * 1998-12-22 2000-12-19 Mohammad; Owais Retractable needle assembly and method of making the same
US6368315B1 (en) 1999-06-23 2002-04-09 Durect Corporation Composite drug delivery catheter
CA2383572C (en) 1999-10-21 2007-12-11 Alcon Universal Ltd. Sub-tenon drug delivery
US8574146B2 (en) * 2000-04-14 2013-11-05 Attenuex Technologies, Inc. Implant with high vapor pressure medium
US7357794B2 (en) 2002-01-17 2008-04-15 Medtronic Vascular, Inc. Devices, systems and methods for acute or chronic delivery of substances or apparatus to extravascular treatment sites
US6989004B2 (en) 2001-02-28 2006-01-24 Rex Medical, L.P. Apparatus for delivering ablation fluid to treat lesions
US7122042B2 (en) * 2001-03-15 2006-10-17 Lorusso Frank J Apparatuses and methods for transcleral cautery and subretinal drainage
US7431710B2 (en) * 2002-04-08 2008-10-07 Glaukos Corporation Ocular implants with anchors and methods thereof
JP2005517468A (ja) 2002-02-14 2005-06-16 フォトジェネシス インコーポレイテッド 網膜下移植装置および同装置と共に使用されるカニューレ
US7316676B2 (en) 2002-08-20 2008-01-08 Gholam A. Peyman Treatment of retinal detachment
CA2689424A1 (en) 2002-09-29 2004-04-08 Surmodics, Inc. Methods for treatment and/or prevention of retinal disease
US20040199130A1 (en) * 2003-04-03 2004-10-07 Chornenky Victor I. Apparatus and method for treatment of macular degeneration
JP4289919B2 (ja) 2003-05-06 2009-07-01 朝日インテック株式会社 薬液注入装置
ES2564044T3 (es) 2003-06-27 2016-03-17 DePuy Synthes Products, Inc. Células posparto derivadas de tejido del cordón umbilical y métodos de preparación y uso de las mismas
SG183072A1 (en) 2004-01-23 2012-08-30 Iscience Surgical Corp Composite ophthalmic microcannula
EP1720608B1 (en) * 2004-02-12 2010-11-17 NeoVista, Inc. Apparatus for intraocular brachytherapy
US20080058704A1 (en) 2004-04-29 2008-03-06 Michael Hee Apparatus and Method for Ocular Treatment
EP2380622A1 (en) * 2004-04-29 2011-10-26 iScience Interventional Corporation Method for ocular treatment
US20100173866A1 (en) * 2004-04-29 2010-07-08 Iscience Interventional Corporation Apparatus and method for ocular treatment
US20060047250A1 (en) * 2004-08-30 2006-03-02 Hickingbotham Dyson W Fluid delivery device
WO2007002304A2 (en) 2005-06-22 2007-01-04 Vnus Medical Technologies, Inc. Methods and apparatus for introducing tumescent fluid to body tissue
US20070202186A1 (en) 2006-02-22 2007-08-30 Iscience Interventional Corporation Apparatus and formulations for suprachoroidal drug delivery
US8197435B2 (en) 2006-05-02 2012-06-12 Emory University Methods and devices for drug delivery to ocular tissue using microneedle
US20080004596A1 (en) 2006-05-25 2008-01-03 Palo Alto Institute Delivery of agents by microneedle catheter
US20080281292A1 (en) 2006-10-16 2008-11-13 Hickingbotham Dyson W Retractable Injection Port
US20080161845A1 (en) * 2006-11-16 2008-07-03 Mani, Inc. Trocar
US9011467B2 (en) * 2008-08-13 2015-04-21 Silk Road Medical, Inc. Suture delivery device
US8353862B2 (en) * 2007-11-02 2013-01-15 Allergan, Inc. Drug delivery systems and methods
CA2714985C (en) 2008-01-07 2018-05-15 Salutaris Medical Devices, Inc. Methods and devices for minimally-invasive extraocular delivery of radiation to the posterior portion of the eye
WO2009089409A2 (en) * 2008-01-10 2009-07-16 Bausch & Lomb Incorporated Intravitreal injection system having coaxial cannulae and use thereof
US20100081707A1 (en) * 2008-02-21 2010-04-01 Ali Robin R Devices and methods for delivering polynucleotides into retinal cells of the macula and fovea
US8425473B2 (en) * 2009-01-23 2013-04-23 Iscience Interventional Corporation Subretinal access device
AU2010213840B2 (en) * 2009-02-10 2014-03-20 Eyepoint Pharmaceuticals Us, Inc. Ocular trocar assembly
EP2429607A4 (en) * 2009-05-15 2014-01-08 Iscience Interventional Corp METHOD AND DEVICE FOR SUBRETINAL CATHETERIZATION
WO2010141837A1 (en) 2009-06-05 2010-12-09 Vance Products Incorporated, D/B/A/ Cook Urological Incorporated Access sheath and needle assembly for delivering therapeutic material
WO2011053908A1 (en) * 2009-11-02 2011-05-05 Salutaris Medical Devices, Inc. Methods and devices for delivering appropriate minimally-invasive extraocular radiation
WO2012019176A2 (en) * 2010-08-05 2012-02-09 Forsight Vision4 Inc. Implantable therapeutic device
BR112013009205A2 (pt) * 2010-10-15 2016-07-26 Iscience Interventional Corp dispositivo para colocação na esclera de um olho, método para acessar o espaço supracoroidal de um olho, para acessar o espaço subretinal de um olho e para colocar um orifício dentro de um trato escleral em um olho.
US8535268B2 (en) * 2010-12-22 2013-09-17 Alcon Research, Ltd. Device for at least one of injection or aspiration
US8852165B2 (en) 2011-06-16 2014-10-07 II Edward G. Mackay Endoluminal drug delivery devices and methods
WO2013059737A2 (en) 2011-10-19 2013-04-25 Nitinol Devices And Components, Inc. Tissue treatment device and related methods
ES2629858T3 (es) * 2011-10-21 2017-08-16 Synergetics, Inc. Sistema de trócar
WO2013123309A1 (en) 2012-02-15 2013-08-22 The Cleveland Clinic Foundation Catheter assembly and method of treating a vascular disease
ES2842454T3 (es) * 2012-03-20 2021-07-14 Sight Sciences Inc Sistemas de entrega ocular
CA2882184C (en) 2012-08-27 2021-09-07 Clearside Biomedical, Inc. Apparatus and methods for drug delivery using microneedles
US9301795B2 (en) 2012-10-29 2016-04-05 Ablative Solutions, Inc. Transvascular catheter for extravascular delivery
AU2013342275B2 (en) 2012-11-08 2017-11-09 Clearside Biomedical, Inc. Methods and devices for the treatment of ocular diseases in human subjects
JP6594869B2 (ja) * 2013-08-02 2019-10-23 テル ハショメール メディカル リサーチ インフラストラクチュアー アンド サービス エルティーディー． 目に組成物を輸送するためのデバイス
WO2015126694A1 (en) 2014-02-12 2015-08-27 Ethicon Endo-Surgery, Inc. Method and apparatus for suprachoroidal administration of therapeutic agent
US9949874B2 (en) 2014-06-06 2018-04-24 Janssen Biotech, Inc. Therapeutic agent delivery device with convergent lumen
US9925088B2 (en) 2014-06-06 2018-03-27 Janssen Biotech, Inc. Sub-retinal tangential needle catheter guide and introducer
KR102511477B1 (ko) 2014-06-17 2023-03-16 클리어사이드 바이오메디컬, 인코포레이드 안구 후부 질환을 치료하기 위한 방법 및 디바이스
RU2710491C2 (ru) 2014-06-20 2019-12-26 Клиасайд Байомедикал, Инк. Устройство для инъекции лекарственного средства в глазную ткань и способ инъекции лекарственного средства в глазную ткань
US10219936B2 (en) 2014-09-11 2019-03-05 Orbit Biomedical Limited Therapeutic agent delivery device with advanceable cannula and needle
US10322028B2 (en) 2014-09-11 2019-06-18 Orbit Biomedical Limited Method and apparatus for sensing position between layers of an eye
US10064752B2 (en) 2014-09-11 2018-09-04 Orbit Biomedical Limited Motorized suprachoroidal injection of therapeutic agent
US10258502B2 (en) 2014-09-18 2019-04-16 Orbit Biomedical Limited Therapeutic agent delivery device
JP6744864B2 (ja) * 2015-07-30 2020-08-19 テルモ株式会社 医療用の穿刺針
GB201516066D0 (en) 2015-09-10 2015-10-28 Young & Co Llp D Treatment of retinitis pigmentosa
US11273072B2 (en) * 2017-01-13 2022-03-15 Gyroscope Therapeutics Limited Suprachoroidal injection device
US10765843B2 (en) * 2018-12-31 2020-09-08 J.D. Franco & Co., Llc Intravascular devices, systems, and methods to address eye disorders

Also Published As

Publication number Publication date
JP7483826B2 (ja) 2024-05-15
US11554042B2 (en) 2023-01-17
PL3104814T3 (pl) 2021-10-11
WO2015126694A1 (en) 2015-08-27
CN113855385A (zh) 2021-12-31
BR112016018570A2 (pt) 2018-06-26
EP3104814A1 (en) 2016-12-21
BR122020011529B1 (pt) 2022-11-29
JP2019147052A (ja) 2019-09-05
JP2021058723A (ja) 2021-04-15
JP7167197B2 (ja) 2022-11-08
EP3797742A1 (en) 2021-03-31
JP6548229B2 (ja) 2019-07-24
US11058576B2 (en) 2021-07-13
JP6995800B2 (ja) 2022-01-17
ES2871138T3 (es) 2021-10-28
PT3104814T (pt) 2021-06-17
US20190142634A1 (en) 2019-05-16
US20210298951A1 (en) 2021-09-30
US10226379B2 (en) 2019-03-12
US20150223977A1 (en) 2015-08-13
CN110680606B (zh) 2023-07-21
CN106687078A (zh) 2017-05-17
US20190142635A1 (en) 2019-05-16
JP2022186880A (ja) 2022-12-15
CN110680606A (zh) 2020-01-14
JP2017505686A (ja) 2017-02-23
EP3104814B1 (en) 2021-04-07
CN106687078B (zh) 2019-10-25
BR112016018570B1 (pt) 2022-08-30

Similar Documents

Publication Publication Date Title
DK3104814T3 (da) Apparat til suprachoroidal indgivelse af terapeutisk middel
DK3722274T3 (da) 2-perfluorbutylpentan til oftalmisk indgivelse
DK3152153T3 (da) Apparat til avanceret behandling
DK3096741T3 (da) Fremgangsmåde til fremstillingen af hybridosomer
DK3192902T3 (da) Fremgangsmåde til fremstilling af graphenholdige viscosefibre
DK3331876T3 (da) Modulators of ror-gamma
DK3204113T3 (da) Apparat til stimulering af biologisk væv
DK3139986T3 (da) System til administration af terapeutisk gas
DK3137169T3 (da) Hæmmere af lysin-specifik demethylase-1
DK3134530T3 (da) Behandling af hyperbilirubinæmi
DK3174858T3 (da) Fremgangsmåde til fremstilling af pyrazoler
DK3198035T3 (da) Fremgangsmåder til forudsigelse af medicinrespons
DK3466432T3 (da) Fremgangsmåder til behandling af pulmonale non-tuberkuløse mykobakterielle infektioner
DK3310316T3 (da) Apparat til extrakorporal understøtning af præmatur foster
DK3204398T3 (da) Fremgangsmåder til fraseparering af gemcitabin-phosphat diastereoisomerer
DK3240612T3 (da) Fremgangsmåder til behandling af nethindesygdomme
DK3191182T3 (da) Apparat til tilvejebringelse af hypertermiterapi
DK3102213T3 (da) Farmaceutiske sammensætninger til behandlingen af inflammatoriske lidelser
DK3169328T3 (da) Quinolinderivater til behandling af inflammationssygdomme
DK3237045T3 (da) Indretning til indgivelse af lægemidler
DK3233813T3 (da) Fremgangsmåder til fremstilling af oxathiazin-lignende forbindelser
DK3197868T3 (da) N-alkylaryl-5-oxyaryl-octahydro-cyclopenta[c]pyrrol-negative allosteriske modulatorer af nr2b
DK3164394T3 (da) Gls1-inhibitorer til behandling af sygdomme
DK2955158T3 (da) Fremgangsmåde til fremstilling af phosgen
DK3098580T3 (da) Kombinationsvægtindretning