HRP20192182T1 - Agrokemijski pripravci koji sadrže protutijela koja se vežu na sfingolipide - Google Patents

Agrokemijski pripravci koji sadrže protutijela koja se vežu na sfingolipide Download PDF

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HRP20192182T1
HRP20192182T1 HRP20192182TT HRP20192182T HRP20192182T1 HR P20192182 T1 HRP20192182 T1 HR P20192182T1 HR P20192182T T HRP20192182T T HR P20192182TT HR P20192182 T HRP20192182 T HR P20192182T HR P20192182 T1 HRP20192182 T1 HR P20192182T1
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Croatia
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seq
region
cdr1
cdr2
cdr3
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HRP20192182TT
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Peter Verheesen
Chris De Jonghe
Inge Elodie VAN DAELE
Miguel Francesco Coleta De Bolle
João Filipe VELOSO VIEIRA
Karin Thevissen
Bruno Cammue
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Agrosavfe Nv
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Publication of HRP20192182T1 publication Critical patent/HRP20192182T1/hr

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/14—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from fungi, algea or lichens
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A01N37/46—N-acyl derivatives
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/10—Animals; Substances produced thereby or obtained therefrom
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/50—Isolated enzymes; Isolated proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/22—Immunoglobulins specific features characterized by taxonomic origin from camelids, e.g. camel, llama or dromedary
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Claims (8)

1. Agrokemijski pripravak za zaštitu ili tretiranje biljke ili dijela navedene biljke od infekcije ili druge biološke interakcije s biljnom patogenom gljivom, koji sadrži najmanje jedan VHH, koji se specifično veže na glukozilceramid biljne patogene gljive, ili njegov ulomak pri čemu zadržava specifičnost vezanja izvornog VHH, naznačen time što se koncentracija navedenog najmanje jednog VHH u agrokemijskom pripravku kreće u rasponu od 0,001 do 50 masenih%.
2. Agrokemijski pripravak prema patentnom zahtjevu 1, naznačen time što nadalje sadrži agrokemijski prihvatljiv nosač i/ili jednu ili više prikladnih pomoćnih tvari.
3. Agrokemijski pripravak prema patentnom zahtjevu 1, naznačen time što je rod navedene biljne patogene gljive odabran iz skupine koja sadrži rodove Alternaria, Ascochyta, Botrytis, Cercospora, Colletotrichum, Diplodia, Erysiphe, Fusarium, Leptosphaeria, Gaeumanomyces, Helminthosporium, Macrophomina, Nectria, Penicillium, Peronospora, Phoma, Phymatotrichum, Phytophthora, Plasmopara, Podosphaera, Puccinia, Pyrenophora, Pyricularia, Pythium, Rhizoctonia, Scerotium, Sclerotinia, Septoria, Thielaviopsis, Uncinula, Venturia, Verticillium, Magnaporthe, Blumeria, Mycosphaerella, Ustilago, Melampsora, Phakopsora, Monilinia, Mucor, Rhizopus, i Aspergillus.
4. Agrokemijski pripravak prema bilo kojem od patentnih zahtjeva 1 do 3, naznačen time što navedeni najmanje jedan VHH sadrži jednu ili više kombinacija odabranih iz skupine koja sadrži: CDR1 regiju koja ima SEQ ID NO: 85, CDR2 regiju koja ima SEQ ID NO: 169, i CDR3 regiju koja ima SEQ ID NO: 253, i/ili CDR1 regiju koja ima SEQ ID NO: 86, CDR2 regiju koja ima SEQ ID NO: 170, i CDR3 regiju koja ima SEQ ID NO: 254, i/ili CDR1 regiju koja ima SEQ ID NO: 87, CDR2 regiju koja ima SEQ ID NO: 171, i CDR3 regiju koja ima SEQ ID NO: 255, i/ili CDR1 regiju koja ima SEQ ID NO: 88, CDR2 regiju koja ima SEQ ID NO: 172, i CDR3 regiju koja ima SEQ ID NO: 256, i/ili CDR1 regiju koja ima SEQ ID NO: 89, CDR2 regiju koja ima SEQ ID NO: 173, i CDR3 regiju koja ima SEQ ID NO: 257, i/ili CDR1 regiju koja ima SEQ ID NO: 90, CDR2 regiju koja ima SEQ ID NO: 174, i CDR3 regiju koja ima SEQ ID NO: 258, i/ili CDR1 regiju koja ima SEQ ID NO: 91, CDR2 regiju koja ima SEQ ID NO: 175, i CDR3 regiju koja ima SEQ ID NO: 259, i/ili CDR1 regiju koja ima SEQ ID NO: 92, CDR2 regiju koja ima SEQ ID NO: 176, i CDR3 regiju koja ima SEQ ID NO: 260, i/ili CDR1 regiju koja ima SEQ ID NO: 93, CDR2 regiju koja ima SEQ ID NO: 177, i CDR3 regiju koja ima SEQ ID NO: 261, i/ili CDR1 regiju koja ima SEQ ID NO: 94, CDR2 regiju koja ima SEQ ID NO: 178, i CDR3 regiju koja ima SEQ ID NO: 262, i/ili CDR1 regiju koja ima SEQ ID NO: 95, CDR2 regiju koja ima SEQ ID NO: 179, i CDR3 regiju koja ima SEQ ID NO: 263, i/ili CDR1 regiju koja ima SEQ ID NO: 96, CDR2 regiju koja ima SEQ ID NO: 180, i CDR3 regiju koja ima SEQ ID NO: 264, i/ili CDR1 regiju koja ima SEQ ID NO: 97, CDR2 regiju koja ima SEQ ID NO: 181, i CDR3 regiju koja ima SEQ ID NO: 265, i/ili CDR1 regiju koja ima SEQ ID NO: 98, CDR2 regiju koja ima SEQ ID NO: 182, i CDR3 regiju koja ima SEQ ID NO: 266, i/ili CDR1 regiju koja ima SEQ ID NO: 99, CDR2 regiju koja ima SEQ ID NO: 183, i CDR3 regiju koja ima SEQ ID NO: 267, i/ili CDR1 regiju koja ima SEQ ID NO: 100, CDR2 regiju koja ima SEQ ID NO: 184, i CDR3 regiju koja ima SEQ ID NO: 268, i/ili CDR1 regiju koja ima SEQ ID NO: 101, CDR2 regiju koja ima SEQ ID NO: 185, i CDR3 regiju koja ima SEQ ID NO: 269, i/ili CDR1 regiju koja ima SEQ ID NO: 102, CDR2 regiju koja ima SEQ ID NO: 186, i CDR3 regiju koja ima SEQ ID NO: 270, i/ili CDR1 regiju koja ima SEQ ID NO: 103, CDR2 regiju koja ima SEQ ID NO: 187, i CDR3 regiju koja ima SEQ ID NO: 271, i/ili CDR1 regiju koja ima SEQ ID NO: 104, CDR2 regiju koja ima SEQ ID NO: 188, i CDR3 regiju koja ima SEQ ID NO: 272, i/ili CDR1 regiju koja ima SEQ ID NO: 105, CDR2 regiju koja ima SEQ ID NO: 189, i CDR3 regiju koja ima SEQ ID NO: 273, i/ili CDR1 regiju koja ima SEQ ID NO: 106, CDR2 regiju koja ima SEQ ID NO: 190, i CDR3 regiju koja ima SEQ ID NO: 274, i/ili CDR1 regiju koja ima SEQ ID NO: 107, CDR2 regiju koja ima SEQ ID NO: 191, i CDR3 regiju koja ima SEQ ID NO: 275, i/ili CDR1 regiju koja ima SEQ ID NO: 108, CDR2 regiju koja ima SEQ ID NO: 192, i CDR3 regiju koja ima SEQ ID NO: 276, i/ili CDR1 regiju koja ima SEQ ID NO: 109, CDR2 regiju koja ima SEQ ID NO: 193, i CDR3 regiju koja ima SEQ ID NO: 277, i/ili CDR1 regiju koja ima SEQ ID NO: 110, CDR2 regiju koja ima SEQ ID NO: 194, i CDR3 regiju koja ima SEQ ID NO: 278, i/ili CDR1 regiju koja ima SEQ ID NO: 111, CDR2 regiju koja ima SEQ ID NO: 195, i CDR3 regiju koja ima SEQ ID NO: 279, i/ili CDR1 regiju koja ima SEQ ID NO: 112, CDR2 regiju koja ima SEQ ID NO: 196, i CDR3 regiju koja ima SEQ ID NO: 280, i/ili CDR1 regiju koja ima SEQ ID NO: 113, CDR2 regiju koja ima SEQ ID NO: 197, i CDR3 regiju koja ima SEQ ID NO: 281, i/ili CDR1 regiju koja ima SEQ ID NO: 114, CDR2 regiju koja ima SEQ ID NO: 198, i CDR3 regiju koja ima SEQ ID NO: 282, i/ili CDR1 regiju koja ima SEQ ID NO: 115, CDR2 regiju koja ima SEQ ID NO: 199, i CDR3 regiju koja ima SEQ ID NO: 283, i/ili CDR1 regiju koja ima SEQ ID NO: 116, CDR2 regiju koja ima SEQ ID NO: 200, i CDR3 regiju koja ima SEQ ID NO: 284, i/ili CDR1 regiju koja ima SEQ ID NO: 117, CDR2 regiju koja ima SEQ ID NO: 201, i CDR3 regiju koja ima SEQ ID NO: 285, i/ili CDR1 regiju koja ima SEQ ID NO: 118, CDR2 regiju koja ima SEQ ID NO: 202, i CDR3 regiju koja ima SEQ ID NO: 286, i/ili CDR1 regiju koja ima SEQ ID NO: 119, CDR2 regiju koja ima SEQ ID NO: 203, i CDR3 regiju koja ima SEQ ID NO: 287, i/ili CDR1 regiju koja ima SEQ ID NO: 120, CDR2 regiju koja ima SEQ ID NO: 204, i CDR3 regiju koja ima SEQ ID NO: 288, i/ili CDR1 regiju koja ima SEQ ID NO: 121, CDR2 regiju koja ima SEQ ID NO: 205, i CDR3 regiju koja ima SEQ ID NO: 289, i/ili CDR1 regiju koja ima SEQ ID NO: 122, CDR2 regiju koja ima SEQ ID NO: 206, i CDR3 regiju koja ima SEQ ID NO: 290, i/ili CDR1 regiju koja ima SEQ ID NO: 123, CDR2 regiju koja ima SEQ ID NO: 207, i CDR3 regiju koja ima SEQ ID NO: 291, i/ili CDR1 regiju koja ima SEQ ID NO: 124, CDR2 regiju koja ima SEQ ID NO: 208, i CDR3 regiju koja ima SEQ ID NO: 292, i/ili CDR1 regiju koja ima SEQ ID NO: 125, CDR2 regiju koja ima SEQ ID NO: 209, i CDR3 regiju koja ima SEQ ID NO: 293, i/ili CDR1 regiju koja ima SEQ ID NO: 126, CDR2 regiju koja ima SEQ ID NO: 210, i CDR3 regiju koja ima SEQ ID NO: 294, i/ili CDR1 regiju koja ima SEQ ID NO: 127, CDR2 regiju koja ima SEQ ID NO: 211, i CDR3 regiju koja ima SEQ ID NO: 295, i/ili CDR1 regiju koja ima SEQ ID NO: 128, CDR2 regiju koja ima SEQ ID NO: 212, i CDR3 regiju koja ima SEQ ID NO: 296, i/ili CDR1 regiju koja ima SEQ ID NO: 129, CDR2 regiju koja ima SEQ ID NO: 213, i CDR3 regiju koja ima SEQ ID NO: 297, i/ili CDR1 regiju koja ima SEQ ID NO: 130, CDR2 regiju koja ima SEQ ID NO: 214, i CDR3 regiju koja ima SEQ ID NO: 298, i/ili CDR1 regiju koja ima SEQ ID NO: 131, CDR2 regiju koja ima SEQ ID NO: 215, i CDR3 regiju koja ima SEQ ID NO: 299, i/ili CDR1 regiju koja ima SEQ ID NO: 132, CDR2 regiju koja ima SEQ ID NO: 216, i CDR3 regiju koja ima SEQ ID NO: 300, i/ili CDR1 regiju koja ima SEQ ID NO: 133, CDR2 regiju koja ima SEQ ID NO: 217, i CDR3 regiju koja ima SEQ ID NO: 301, i/ili CDR1 regiju koja ima SEQ ID NO: 134, CDR2 regiju koja ima SEQ ID NO: 218, i CDR3 regiju koja ima SEQ ID NO: 302, i/ili CDR1 regiju koja ima SEQ ID NO: 135, CDR2 regiju koja ima SEQ ID NO: 219, i CDR3 regiju koja ima SEQ ID NO: 303, i/ili CDR1 regiju koja ima SEQ ID NO: 136, CDR2 regiju koja ima SEQ ID NO: 220, i CDR3 regiju koja ima SEQ ID NO: 304, i/ili CDR1 regiju koja ima SEQ ID NO: 137, CDR2 regiju koja ima SEQ ID NO: 221, i CDR3 regiju koja ima SEQ ID NO: 305, i/ili CDR1 regiju koja ima SEQ ID NO: 138, CDR2 regiju koja ima SEQ ID NO: 222, i CDR3 regiju koja ima sekvencu aminokiseline NRY, i/ili CDR1 regiju koja ima SEQ ID NO: 139, CDR2 regiju koja ima SEQ ID NO: 223, i CDR3 regiju koja ima SEQ ID NO: 306, i/ili CDR1 regiju koja ima SEQ ID NO: 140, CDR2 regiju koja ima SEQ ID NO: 224, i CDR3 regiju koja ima SEQ ID NO: 307, i/ili CDR1 regiju koja ima SEQ ID NO: 141, CDR2 regiju koja ima SEQ ID NO: 225, i CDR3 regiju koja ima SEQ ID NO: 308, i/ili CDR1 regiju koja ima SEQ ID NO: 142, CDR2 regiju koja ima SEQ ID NO: 226, i CDR3 regiju koja ima SEQ ID NO: 309, i/ili CDR1 regiju koja ima SEQ ID NO: 143, CDR2 regiju koja ima SEQ ID NO: 227, i CDR3 regiju koja ima SEQ ID NO: 310, i/ili CDR1 regiju koja ima SEQ ID NO: 144, CDR2 regiju koja ima SEQ ID NO: 228, i CDR3 regiju koja ima SEQ ID NO: 311, i/ili CDR1 regiju koja ima SEQ ID NO: 145, CDR2 regiju koja ima SEQ ID NO: 229, i CDR3 regiju koja ima SEQ ID NO: 312, i/ili CDR1 regiju koja ima SEQ ID NO: 146, CDR2 regiju koja ima SEQ ID NO: 230, i CDR3 regiju koja ima SEQ ID NO: 313, i/ili CDR1 regiju koja ima SEQ ID NO: 147, CDR2 regiju koja ima SEQ ID NO: 231, i CDR3 regiju koja ima SEQ ID NO: 314, i/ili CDR1 regiju koja ima SEQ ID NO: 148, CDR2 regiju koja ima SEQ ID NO: 232, i CDR3 regiju koja ima SEQ ID NO: 315, i/ili CDR1 regiju koja ima SEQ ID NO: 149, CDR2 regiju koja ima SEQ ID NO: 233, i CDR3 regiju koja ima SEQ ID NO: 316, i/ili CDR1 regiju koja ima SEQ ID NO: 150, CDR2 regiju koja ima SEQ ID NO: 234, i CDR3 regiju koja ima SEQ ID NO: 317, i/ili CDR1 regiju koja ima SEQ ID NO: 151, CDR2 regiju koja ima SEQ ID NO: 235, i CDR3 regiju koja ima SEQ ID NO: 318, i/ili CDR1 regiju koja ima SEQ ID NO: 152, CDR2 regiju koja ima SEQ ID NO: 236, i CDR3 regiju koja ima SEQ ID NO: 319, i/ili CDR1 regiju koja ima SEQ ID NO: 153, CDR2 regiju koja ima SEQ ID NO: 237, i CDR3 regiju koja ima SEQ ID NO: 320, i/ili CDR1 regiju koja ima SEQ ID NO: 154, CDR2 regiju koja ima SEQ ID NO: 238, i CDR3 regiju koja ima SEQ ID NO: 321, i/ili CDR1 regiju koja ima SEQ ID NO: 155, CDR2 regiju koja ima SEQ ID NO: 239, i CDR3 regiju koja ima SEQ ID NO: 322, i/ili CDR1 regiju koja ima SEQ ID NO: 156, CDR2 regiju koja ima SEQ ID NO: 240, i CDR3 regiju koja ima SEQ ID NO: 323, i/ili CDR1 regiju koja ima SEQ ID NO: 157, CDR2 regiju koja ima SEQ ID NO: 241, i CDR3 regiju koja ima SEQ ID NO: 324, i/ili CDR1 regiju koja ima SEQ ID NO: 158, CDR2 regiju koja ima SEQ ID NO: 242, i CDR3 regiju koja ima SEQ ID NO: 325, i/ili CDR1 regiju koja ima SEQ ID NO: 159, CDR2 regiju koja ima SEQ ID NO: 243, i CDR3 regiju koja ima SEQ ID NO: 326, i/ili CDR1 regiju koja ima SEQ ID NO: 160, CDR2 regiju koja ima SEQ ID NO: 244, i CDR3 regiju koja ima SEQ ID NO: 327, i/ili CDR1 regiju koja ima SEQ ID NO: 161, CDR2 regiju koja ima SEQ ID NO: 245, i CDR3 regiju koja ima SEQ ID NO: 328, i/ili CDR1 regiju koja ima SEQ ID NO: 162, CDR2 regiju koja ima SEQ ID NO: 246, i CDR3 regiju koja ima SEQ ID NO: 329, i/ili CDR1 regiju koja ima SEQ ID NO: 163, CDR2 regiju koja ima SEQ ID NO: 247, i CDR3 regiju koja ima SEQ ID NO: 330, i/ili CDR1 regiju koja ima SEQ ID NO: 164, CDR2 regiju koja ima SEQ ID NO: 248, i CDR3 regiju koja ima SEQ ID NO: 331, i/ili CDR1 regiju koja ima SEQ ID NO: 165, CDR2 regiju koja ima SEQ ID NO: 249, i CDR3 regiju koja ima SEQ ID NO: 332, i/ili CDR1 regiju koja ima SEQ ID NO: 166, CDR2 regiju koja ima SEQ ID NO: 250, i CDR3 regiju koja ima SEQ ID NO: 333, i/ili CDR1 regiju koja ima SEQ ID NO: 167, CDR2 regiju koja ima SEQ ID NO: 251, i CDR3 regiju koja ima SEQ ID NO: 334, i/ili CDR1 regiju koja ima SEQ ID NO: 168, CDR2 regiju koja ima SEQ ID NO: 252, i CDR3 regiju koja ima SEQ ID NO: 335.
5. Upotreba agrokemijskog pripravka prema bilo kojem od patentnih zahtjeva 1 do 4 kao fungicidnog i/ili fungistatskog sredstva.
6. Postupak zaštite ili tretiranja biljke ili dijela navedene biljke od infekcije ili druge biološke interakcije s biljnom patogenom gljivom, koji obuhvaća barem korak primjene na navedenu biljku ili na dio navedene biljke, agrokemijskog pripravka prema bilo kojem od patentnih zahtjeva 1 do 4, pod uvjetima koji su učinkoviti za zaštitu ili tretiranje navedene biljke ili dijela navedene biljke od navedene infekcije ili biološke interakcije s navedenom biljnom patogenom gljivom.
7. Postupak tretmana nakon berbe za zaštitu ili tretiranje ubrane biljke ili ubranog dijela navedene biljke od infekcije ili druge biološke interakcije s biljnom patogenom gljivom, koji barem uključuje korak primjene na navedenu ubranu biljku ili na ubrani dio navedene biljke, agrokemijskog pripravka prema bilo kojem od patentnih zahtjeva 1 do 4, pod uvjetima koji su učinkoviti za zaštitu ili tretiranje navedene ubrane biljke ili ubranog dijela navedene biljke od navedene infekcije ili biološke interakcije s navedenom biljnom patogenom gljivom.
8. Postupak inhibicije ili ubijanja rasta biljne patogene gljive, naznačen time što obuhvaća barem korak primjene na biljku ili na dio navedene biljke, agrokemijskog pripravka prema bilo kojem od patentnih zahtjeva 1 do 4.
HRP20192182TT 2013-04-29 2019-12-04 Agrokemijski pripravci koji sadrže protutijela koja se vežu na sfingolipide HRP20192182T1 (hr)

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