ECSP13012710A - Método de tratamiento con inhibidores selectivos de bcl-2 - Google Patents
Método de tratamiento con inhibidores selectivos de bcl-2Info
- Publication number
- ECSP13012710A ECSP13012710A ECSP13012710A ECSP13012710A EC SP13012710 A ECSP13012710 A EC SP13012710A EC SP13012710 A ECSP13012710 A EC SP13012710A EC SP13012710 A ECSP13012710 A EC SP13012710A
- Authority
- EC
- Ecuador
- Prior art keywords
- bcl
- treatment method
- selective inhibitors
- activity
- treatment
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Abstract
Métodos de tratamiento de lupus eritematoso sistémico, nefritis lúpica o síndrome de Sjogren con compuestos que inhiben selectivamente la actividad de las proteínas anti apoptóticas Bcl 2. Específicamente, la presente invención está dirigida al tratamiento con compuestos que inhiben selectivamente la actividad de proteínas Bcl-2, con una menor afinidad por la inhibición de la actividad de otras proteínas de la familia Bcl-2, incluyendo Bcl- xL.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US41668910P | 2010-11-23 | 2010-11-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
ECSP13012710A true ECSP13012710A (es) | 2013-08-30 |
Family
ID=45218888
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ECSP13012710 ECSP13012710A (es) | 2010-11-23 | 2013-06-21 | Método de tratamiento con inhibidores selectivos de bcl-2 |
Country Status (36)
Country | Link |
---|---|
US (5) | US20120129853A1 (es) |
EP (2) | EP3028702B1 (es) |
JP (2) | JP5876067B2 (es) |
KR (3) | KR20180030257A (es) |
CN (2) | CN103402521B (es) |
AR (1) | AR083946A1 (es) |
AU (2) | AU2011332000B2 (es) |
BR (1) | BR112013012854B1 (es) |
CA (1) | CA2820618C (es) |
CL (1) | CL2013001458A1 (es) |
CR (1) | CR20130268A (es) |
CY (1) | CY1118442T1 (es) |
DK (1) | DK2642999T3 (es) |
DO (1) | DOP2017000056A (es) |
EC (1) | ECSP13012710A (es) |
ES (2) | ES2701603T3 (es) |
GT (1) | GT201300136A (es) |
HR (1) | HRP20161762T1 (es) |
HU (1) | HUE031267T2 (es) |
IL (2) | IL226490A (es) |
LT (1) | LT2642999T (es) |
MX (1) | MX346201B (es) |
MY (2) | MY165884A (es) |
NZ (2) | NZ610746A (es) |
PH (1) | PH12016500939A1 (es) |
PL (1) | PL2642999T3 (es) |
PT (1) | PT2642999T (es) |
RS (1) | RS55545B1 (es) |
RU (1) | RU2593231C2 (es) |
SG (2) | SG190399A1 (es) |
SI (1) | SI2642999T1 (es) |
TW (2) | TWI535701B (es) |
UA (2) | UA113157C2 (es) |
UY (1) | UY33746A (es) |
WO (1) | WO2012071374A1 (es) |
ZA (1) | ZA201303589B (es) |
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