PL2642999T3 - Sposoby leczenia z zastosowaniem selektywnych inhibitorów bcl-2 - Google Patents
Sposoby leczenia z zastosowaniem selektywnych inhibitorów bcl-2Info
- Publication number
- PL2642999T3 PL2642999T3 PL11793928T PL11793928T PL2642999T3 PL 2642999 T3 PL2642999 T3 PL 2642999T3 PL 11793928 T PL11793928 T PL 11793928T PL 11793928 T PL11793928 T PL 11793928T PL 2642999 T3 PL2642999 T3 PL 2642999T3
- Authority
- PL
- Poland
- Prior art keywords
- inhibitors
- treatment
- methods
- selective bcl
- bcl
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41668910P | 2010-11-23 | 2010-11-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2642999T3 true PL2642999T3 (pl) | 2017-04-28 |
Family
ID=45218888
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL11793928T PL2642999T3 (pl) | 2010-11-23 | 2011-11-22 | Sposoby leczenia z zastosowaniem selektywnych inhibitorów bcl-2 |
Country Status (36)
| Country | Link |
|---|---|
| US (5) | US20120129853A1 (pl) |
| EP (2) | EP2642999B1 (pl) |
| JP (2) | JP5876067B2 (pl) |
| KR (3) | KR20190109590A (pl) |
| CN (2) | CN103402521B (pl) |
| AR (1) | AR083946A1 (pl) |
| AU (2) | AU2011332000B2 (pl) |
| BR (1) | BR112013012854B1 (pl) |
| CA (1) | CA2820618C (pl) |
| CL (1) | CL2013001458A1 (pl) |
| CR (1) | CR20130268A (pl) |
| CY (1) | CY1118442T1 (pl) |
| DK (1) | DK2642999T3 (pl) |
| DO (1) | DOP2017000056A (pl) |
| EC (1) | ECSP13012710A (pl) |
| ES (2) | ES2701603T3 (pl) |
| GT (1) | GT201300136A (pl) |
| HR (1) | HRP20161762T1 (pl) |
| HU (1) | HUE031267T2 (pl) |
| IL (2) | IL226490A (pl) |
| LT (1) | LT2642999T (pl) |
| MX (1) | MX346201B (pl) |
| MY (2) | MY191300A (pl) |
| NZ (2) | NZ610746A (pl) |
| PH (1) | PH12016500939B1 (pl) |
| PL (1) | PL2642999T3 (pl) |
| PT (1) | PT2642999T (pl) |
| RS (1) | RS55545B1 (pl) |
| RU (1) | RU2593231C2 (pl) |
| SG (2) | SG190399A1 (pl) |
| SI (1) | SI2642999T1 (pl) |
| TW (2) | TWI620736B (pl) |
| UA (2) | UA119150C2 (pl) |
| UY (1) | UY33746A (pl) |
| WO (1) | WO2012071374A1 (pl) |
| ZA (1) | ZA201303589B (pl) |
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| US8546399B2 (en) | 2009-05-26 | 2013-10-01 | Abbvie Inc. | Apoptosis inducing agents for the treatment of cancer and immune and autoimmune diseases |
| US20220315555A1 (en) | 2009-05-26 | 2022-10-06 | Abbvie Inc. | Apoptosis inducing agents for the treatment of cancer and immune and autoimmune diseases |
| US9034875B2 (en) | 2009-05-26 | 2015-05-19 | Abbvie Inc. | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases |
| NZ702485A (en) | 2010-06-03 | 2016-04-29 | Pharmacyclics Llc | The use of inhibitors of bruton’s tyrosine kinase (btk) |
| US20120277210A1 (en) | 2010-10-29 | 2012-11-01 | Abbott Laboratories | Solid dispersions containing an apoptosis-inducing agent |
| UA113500C2 (xx) | 2010-10-29 | 2017-02-10 | Одержані екструзією розплаву тверді дисперсії, що містять індукуючий апоптоз засіб | |
| NZ610746A (en) | 2010-11-23 | 2015-06-26 | Abbvie Bahamas Ltd | Methods of treatment using selective bcl-2 inhibitors |
| JP6141188B2 (ja) | 2010-11-23 | 2017-06-07 | アッヴィ・インコーポレイテッド | アポトーシス誘導剤の塩および結晶の形態 |
| JP2015502366A (ja) | 2011-12-13 | 2015-01-22 | バック インスティテュート フォー リサーチ オン エイジング | 薬物療法を改善するための方法 |
| CA2879570A1 (en) | 2012-07-24 | 2014-01-30 | Pharmacyclics, Inc. | Mutations associated with resistance to inhibitors of bruton's tyrosine kinase (btk) |
| CA2884307A1 (en) | 2012-09-07 | 2014-03-13 | Genentech, Inc. | Combination therapy of a type ii anti-cd20 antibody with a selective bcl-2 inhibitor |
| US20150241429A1 (en) * | 2012-09-11 | 2015-08-27 | Hospital For Special Surgery | Irhom2 inhibition for the treatment of complement mediated disorders |
| TWI735759B (zh) | 2013-03-13 | 2021-08-11 | 愛爾蘭商艾伯維愛爾蘭無限公司 | 細胞凋亡誘導劑之中間體及其製備方法 |
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| JP2017509336A (ja) | 2014-03-20 | 2017-04-06 | ファーマサイクリックス エルエルシー | ホスホリパーゼｃガンマ２及び耐性に関連した変異 |
| CN106456699B (zh) * | 2014-05-05 | 2021-07-02 | 生物风险投资有限责任公司 | 作为抗老化剂抑制抗凋亡的Bcl-2蛋白的组合物和方法 |
| EP3179991B1 (en) | 2014-08-11 | 2021-10-06 | Acerta Pharma B.V. | Therapeutic combinations of a btk inhibitor and a bcl-2 inhibitor |
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| AU2016349279A1 (en) | 2015-11-03 | 2018-05-10 | Board Of Regents, The University Of Texas System | Combination of Bcl-2 inhibitor and MEK inhibitor for the treatment of cancer |
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| MX2020009757A (es) | 2018-07-31 | 2020-10-08 | Ascentage Pharma Suzhou Co Ltd | Producto combinado de inhibidor de bcl-2 e inhibidor de mdm2 y uso de este en la prevencion y/o tratamiento de enfermedades. |
| AU2019314819A1 (en) | 2018-07-31 | 2020-10-22 | Ascentage Pharma (Suzhou) Co., Ltd. | Combination product of Bcl-2 inhibitor and chemotherapeutic agent and use thereof in the prevention and/or treatment of diseases |
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| CN113825754B (zh) | 2019-05-24 | 2023-09-22 | 正大天晴药业集团股份有限公司 | 包括甲基和三氟甲基的双取代磺酰胺类选择性bcl-2抑制剂 |
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