HRP20180152T1 - Sojevi bakterija koji su izolirani iz svinja - Google Patents
Sojevi bakterija koji su izolirani iz svinja Download PDFInfo
- Publication number
- HRP20180152T1 HRP20180152T1 HRP20180152TT HRP20180152T HRP20180152T1 HR P20180152 T1 HRP20180152 T1 HR P20180152T1 HR P20180152T T HRP20180152T T HR P20180152TT HR P20180152 T HRP20180152 T HR P20180152T HR P20180152 T1 HRP20180152 T1 HR P20180152T1
- Authority
- HR
- Croatia
- Prior art keywords
- bacterial strains
- ncimb
- lactic acid
- strains according
- acid bacterial
- Prior art date
Links
- 230000001580 bacterial effect Effects 0.000 title claims 15
- 241000282887 Suidae Species 0.000 title 1
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims 20
- 235000014655 lactic acid Nutrition 0.000 claims 10
- 239000004310 lactic acid Substances 0.000 claims 10
- 206010012735 Diarrhoea Diseases 0.000 claims 4
- 208000028774 intestinal disease Diseases 0.000 claims 2
- 208000002551 irritable bowel syndrome Diseases 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 239000006041 probiotic Substances 0.000 claims 2
- 235000018291 probiotics Nutrition 0.000 claims 2
- 208000011580 syndromic disease Diseases 0.000 claims 2
- 208000004998 Abdominal Pain Diseases 0.000 claims 1
- 206010000087 Abdominal pain upper Diseases 0.000 claims 1
- 241000894006 Bacteria Species 0.000 claims 1
- 206010009900 Colitis ulcerative Diseases 0.000 claims 1
- 206010010774 Constipation Diseases 0.000 claims 1
- 208000011231 Crohn disease Diseases 0.000 claims 1
- 241000588724 Escherichia coli Species 0.000 claims 1
- 241000124008 Mammalia Species 0.000 claims 1
- 241001465754 Metazoa Species 0.000 claims 1
- 206010051606 Necrotising colitis Diseases 0.000 claims 1
- 206010039438 Salmonella Infections Diseases 0.000 claims 1
- 241001354013 Salmonella enterica subsp. enterica serovar Enteritidis Species 0.000 claims 1
- 201000006704 Ulcerative Colitis Diseases 0.000 claims 1
- 239000003242 anti bacterial agent Substances 0.000 claims 1
- 230000000845 anti-microbial effect Effects 0.000 claims 1
- 229940088710 antibiotic agent Drugs 0.000 claims 1
- 235000015872 dietary supplement Nutrition 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 208000035475 disorder Diseases 0.000 claims 1
- 230000009429 distress Effects 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 201000006549 dyspepsia Diseases 0.000 claims 1
- 206010016766 flatulence Diseases 0.000 claims 1
- 235000013305 food Nutrition 0.000 claims 1
- 235000013373 food additive Nutrition 0.000 claims 1
- 239000002778 food additive Substances 0.000 claims 1
- 201000000117 functional diarrhea Diseases 0.000 claims 1
- 244000005709 gut microbiome Species 0.000 claims 1
- 230000002757 inflammatory effect Effects 0.000 claims 1
- 208000004995 necrotizing enterocolitis Diseases 0.000 claims 1
- 201000006195 perinatal necrotizing enterocolitis Diseases 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 230000000291 postprandial effect Effects 0.000 claims 1
- 230000000529 probiotic effect Effects 0.000 claims 1
- 206010039447 salmonellosis Diseases 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
- A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
- A23K10/18—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/225—Lactobacillus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/225—Lactobacillus
- C12R2001/23—Lactobacillus acidophilus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/225—Lactobacillus
- C12R2001/25—Lactobacillus plantarum
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Mycology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Food Science & Technology (AREA)
- Epidemiology (AREA)
- Nutrition Science (AREA)
- Animal Husbandry (AREA)
- Physiology (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Rheumatology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Claims (13)
1. Svinjski soj bakterija mliječne kiseline naznačen time da je odabran od
(i) NCIMB 41846;
(ii) NCIMB 41847;
(iii) NCIMB 41848;
(iv) NCIMB 41849;
(v) NCIMB 41850;
(vi) NCIMB 42008;
(vii) NCIMB 42009;
(viii) NCIMB 42010;
(ix) NCIMB 42011;
(x) NCIMB 42012;
ili bilo koja kombinacija dva ili više navedenih.
2. Pripravak naznačen time da sadrži jedan ili više bakterijskih sojeva mliječne kiseline prema zahtjevu 1 i farmaceutski prihvatljiv ekscipijent, nosač ili sredstvo za otapanje.
3. Probiotski pripravak naznačen time da sadrži bakterijske sojeve mliječne kiseline prema zahtjevu 1.
4. Jedan ili više bakterijskih sojeva mliječne kiseline prema zahtjevu 1 naznačen time da je za upotrebu u medicini.
5. Jedan ili više bakterijskih sojeva mliječne kiseline za upotrebu prema zahtjevu 4, naznačen time da su jedan ili više bakterijskih sojeva mliječne kiseline za upotrebu za poboljšanje crijevne mikroflore, te što jedan ili više bakterijskih sojeva mliječne kiseline izražava antimikrobnu aktivnost prema E. coli i/ili S. enteritidis.
6. Jedan ili više bakterijskih sojeva mliječne kiseline prema zahtjevu 1 naznačen time da je za upotrebu u liječenju crijevnog poremećaja kod subjekta.
7. Jedan ili više bakterijskih sojeva mliječne kiseline prema zahtjevu 6, naznačen time da je subjekt sisavac, poželjno čovjek.
8. Jedan ili više bakterijskih sojeva mliječne kiseline prema zahtjevu 6, naznačen time da je crijevni poremećaj salmoneloza, sindrom iritabilnog crijeva (IBS), upalni crijevni poremećaj (IBD), funkcionalna dispepsija, funkcionalna konstipacija, funkcionalna dijareja (uključujući dijareju koja je povezana s antibioticima, dijareju povezanu s putovanjem u pedijatrijsku dijareja), funkcionalna bol u trbuhu, funkcionalna nadutost, sindrom epigastrične boli, postprandijalni distres sindrom, Crohnova bolest, ulcerozni kolitis, nekrotizirajući enterokolitis, te njihove kombinacije.
9. Hrana za životinje naznačena time da sadrži jedan ili više bakterijskih sojeva prema zahtjevu 1.
10. Prehrambeni proizvod naznačen time da sadrži jedan ili više bakterijskih sojeva prema zahtjevu 1.
11. Prehrambeni dodatak naznačen time da sadrži jedan ili više bakterijskih sojeva prema zahtjevu 1.
12. Aditiv za hranu naznačen time da sadrži jedan ili više bakterijskih sojeva prema zahtjevu 1.
13. Postupak za dobivanje probiotika, naznačen time da navedeni postupak sadrži kultiviranje bakterijskog soja prema zahtjevu 1.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1112091.2A GB201112091D0 (en) | 2011-07-14 | 2011-07-14 | Bacterial strains isolated from pigs |
| EP12737592.1A EP2732023B1 (en) | 2011-07-14 | 2012-07-13 | Bacterial strains isolated from pigs |
| PCT/GB2012/051686 WO2013008039A2 (en) | 2011-07-14 | 2012-07-13 | Bacterial strains isolated from pigs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20180152T1 true HRP20180152T1 (hr) | 2018-03-09 |
Family
ID=44586578
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20180152TT HRP20180152T1 (hr) | 2011-07-14 | 2018-01-26 | Sojevi bakterija koji su izolirani iz svinja |
Country Status (20)
| Country | Link |
|---|---|
| US (4) | US9539293B2 (hr) |
| EP (1) | EP2732023B1 (hr) |
| CN (2) | CN109777746A (hr) |
| BR (1) | BR112014000835A2 (hr) |
| CA (1) | CA2841576A1 (hr) |
| CY (1) | CY1119911T1 (hr) |
| DK (1) | DK2732023T3 (hr) |
| ES (1) | ES2656037T3 (hr) |
| GB (1) | GB201112091D0 (hr) |
| HR (1) | HRP20180152T1 (hr) |
| HU (1) | HUE036181T2 (hr) |
| LT (1) | LT2732023T (hr) |
| ME (1) | ME02941B (hr) |
| NO (1) | NO2732023T3 (hr) |
| PL (1) | PL2732023T3 (hr) |
| PT (1) | PT2732023T (hr) |
| RS (1) | RS56853B1 (hr) |
| RU (2) | RU2019100532A (hr) |
| SI (1) | SI2732023T1 (hr) |
| WO (1) | WO2013008039A2 (hr) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201112091D0 (en) * | 2011-07-14 | 2011-08-31 | Gt Biolog Ltd | Bacterial strains isolated from pigs |
| GB201117313D0 (en) * | 2011-10-07 | 2011-11-16 | Gt Biolog Ltd | Bacterium for use in medicine |
| GB201306536D0 (en) | 2013-04-10 | 2013-05-22 | Gt Biolog Ltd | Polypeptide and immune modulation |
| WO2016102951A1 (en) | 2014-12-23 | 2016-06-30 | 4D Pharma Research Limited | Pirin polypeptide and immune modulation |
| ME02997B (me) | 2014-12-23 | 2018-10-20 | 4D Pharma Res Ltd | Soj bacteroides thetaiotaomicron i njegova upotreba u smanjenju inflamacije |
| PL3206700T3 (pl) | 2015-06-15 | 2019-11-29 | 4D Pharma Res Ltd | Kompozycje zawierające szczepy bakteryjne |
| CN115364122A (zh) | 2015-06-15 | 2022-11-22 | 4D制药研究有限公司 | 包含细菌菌株的组合物 |
| MA41060B1 (fr) | 2015-06-15 | 2019-11-29 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
| MA41010B1 (fr) | 2015-06-15 | 2020-01-31 | 4D Pharma Res Ltd | Compositions comprenant des souches bactériennes |
| MD3307288T2 (ro) | 2015-06-15 | 2019-12-31 | 4D Pharma Res Ltd | Compoziții care conțin tulpini bacteriene |
| US20180177833A1 (en) * | 2015-06-30 | 2018-06-28 | Perfect (China) Co., Ltd. | Bifidobacteria as probiotic foundation species of gut microbiota |
| EA034677B1 (ru) | 2015-11-20 | 2020-03-05 | 4Д Фарма Рисёрч Лимитед | Композиции для лечения или профилактики рака, содержащие штамм enterococcus gallinarum |
| GB201520497D0 (en) | 2015-11-20 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
| GB201520631D0 (en) | 2015-11-23 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
| GB201520638D0 (en) | 2015-11-23 | 2016-01-06 | 4D Pharma Res Ltd | Compositions comprising bacterial strains |
| CN105343132B (zh) * | 2015-12-08 | 2019-04-26 | 东北农业大学 | 治疗结肠炎的组合物、药物及其制备方法 |
| CN105343133B (zh) * | 2015-12-08 | 2019-11-19 | 东北农业大学 | 一种治疗溃疡性结肠炎的复合益生菌、药物及其制备方法 |
| DK3313423T3 (da) | 2016-03-04 | 2019-05-20 | 4D Pharma Plc | Sammensætninger omfattende bakterielle blautia-stammer til behandling af visceral hypersensitivitet |
| GB201612191D0 (en) | 2016-07-13 | 2016-08-24 | 4D Pharma Plc | Compositions comprising bacterial strains |
| CN105779350B (zh) * | 2016-04-11 | 2019-10-15 | 北京科拓恒通生物技术股份有限公司 | 一种抗肠炎沙门氏菌感染的植物乳杆菌及其用途 |
| TWI802545B (zh) | 2016-07-13 | 2023-05-21 | 英商４Ｄ製藥有限公司 | 包含細菌菌株之組合物 |
| GB201621123D0 (en) | 2016-12-12 | 2017-01-25 | 4D Pharma Plc | Compositions comprising bacterial strains |
| CN106497854B (zh) * | 2017-01-19 | 2019-10-22 | 南京农业大学 | 乳杆菌d8及其应用 |
| LT3630136T (lt) | 2017-05-22 | 2021-06-10 | 4D Pharma Research Limited | Kompozicijos, apimančios bakterines padermes |
| WO2018215782A1 (en) | 2017-05-24 | 2018-11-29 | 4D Pharma Research Limited | Compositions comprising bacterial strain |
| EP3638271B1 (en) | 2017-06-14 | 2020-10-14 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
| HUE052258T2 (hu) | 2017-06-14 | 2021-04-28 | 4D Pharma Res Ltd | Megasphaera nemzetségbe tartozó baktériumtörzset tartalmazó készítmény, és alkalmazása |
| IL283973B (en) | 2017-06-14 | 2022-08-01 | 4D Pharma Res Ltd | Preparations containing bacterial strains |
| KR102250597B1 (ko) * | 2017-11-20 | 2021-05-11 | 경희대학교 산학협력단 | 신규 유산균 및 이의 용도 |
| WO2019141996A1 (en) | 2018-01-19 | 2019-07-25 | 4D Pharma Research Limited | Combination therapy for treating or preventing cancer |
| CN111902153A (zh) | 2018-01-19 | 2020-11-06 | 4D制药研究有限公司 | 用于治疗或预防癌症的组合疗法 |
| MX2020007681A (es) | 2018-01-19 | 2020-09-14 | 4D Pharma Res Limited | Terapia de combinacion para tratar o prevenir el cancer. |
| MX2020007664A (es) | 2018-01-19 | 2020-09-14 | 4D Pharma Res Limited | Terapia de combinacion para tratar o prevenir el cancer. |
| HUE058151T2 (hu) | 2018-03-19 | 2022-07-28 | 4D Pharma Res Ltd | Enterococcusból származó flagellin készítményei terápiában történõ alkalmazásra |
| CN112601534A (zh) | 2018-05-11 | 2021-04-02 | 4D制药研究有限公司 | 包含细菌菌株的组合物 |
| AU2019287370A1 (en) | 2018-06-14 | 2021-01-07 | 4D Pharma Research Ltd | Compositions comprising bacterial strains |
| EP3922256A1 (en) | 2018-06-25 | 2021-12-15 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
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| WO2013008039A2 (en) | 2013-01-17 |
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| HUE036181T2 (hu) | 2018-06-28 |
| ES2656037T3 (es) | 2018-02-22 |
| US20170173089A1 (en) | 2017-06-22 |
| RU2014105461A (ru) | 2015-08-20 |
| RS56853B1 (sr) | 2018-04-30 |
| GB201112091D0 (en) | 2011-08-31 |
| WO2013008039A3 (en) | 2013-03-21 |
| BR112014000835A2 (pt) | 2017-02-21 |
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| CN104080903B (zh) | 2018-06-22 |
| ME02941B (me) | 2018-04-20 |
| PL2732023T3 (pl) | 2018-04-30 |
| US10183046B2 (en) | 2019-01-22 |
| RU2677890C2 (ru) | 2019-01-22 |
| CN109777746A (zh) | 2019-05-21 |
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