MX361355B - Uso del agonista del receptor tipo toll para el tratamiento del cáncer. - Google Patents

Uso del agonista del receptor tipo toll para el tratamiento del cáncer.

Info

Publication number
MX361355B
MX361355B MX2013007967A MX2013007967A MX361355B MX 361355 B MX361355 B MX 361355B MX 2013007967 A MX2013007967 A MX 2013007967A MX 2013007967 A MX2013007967 A MX 2013007967A MX 361355 B MX361355 B MX 361355B
Authority
MX
Mexico
Prior art keywords
toll
receptor agonist
treating cancer
present
receptor
Prior art date
Application number
MX2013007967A
Other languages
English (en)
Other versions
MX2013007967A (es
Inventor
Anatoli Gleiberman
Lyudmila Burdelya
Andrei Gudkov
Original Assignee
Cleveland Biolabs Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cleveland Biolabs Inc filed Critical Cleveland Biolabs Inc
Publication of MX2013007967A publication Critical patent/MX2013007967A/es
Publication of MX361355B publication Critical patent/MX361355B/es

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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
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    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
    • A—HUMAN NECESSITIES
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    • A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
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    • C07—ORGANIC CHEMISTRY
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants

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  • Health & Medical Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
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  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención se refiere a métodos y agentes utilizados para tratar el cáncer en tejidos que expresan el receptor Tipo Toll 5, mediante la proporción de un agonista del receptor Tipo Toll tal como flagelina. La presente invención se refiere también a la protección del hígado de una toxicidad hepática utilizando un agonista del receptor Tipo Toll.
MX2013007967A 2011-01-10 2012-01-10 Uso del agonista del receptor tipo toll para el tratamiento del cáncer. MX361355B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161431313P 2011-01-10 2011-01-10
PCT/US2012/020844 WO2012097012A1 (en) 2011-01-10 2012-01-10 Use of toll-like receptor agonist for treating cancer

Publications (2)

Publication Number Publication Date
MX2013007967A MX2013007967A (es) 2013-08-21
MX361355B true MX361355B (es) 2018-12-04

Family

ID=46507417

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2013007967A MX361355B (es) 2011-01-10 2012-01-10 Uso del agonista del receptor tipo toll para el tratamiento del cáncer.
MX2018014998A MX2018014998A (es) 2011-01-10 2013-07-08 Uso del agonista del receptor tipo toll para el tratamiento del cancer.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2018014998A MX2018014998A (es) 2011-01-10 2013-07-08 Uso del agonista del receptor tipo toll para el tratamiento del cancer.

Country Status (15)

Country Link
US (7) US9376473B2 (es)
EP (1) EP2663367A4 (es)
JP (1) JP6041444B2 (es)
KR (1) KR20140030132A (es)
CN (1) CN103476458B (es)
AU (1) AU2012205681B2 (es)
BR (1) BR112013017283A2 (es)
CA (1) CA2824438A1 (es)
CL (1) CL2013002001A1 (es)
CO (1) CO6781506A2 (es)
EA (1) EA026524B1 (es)
IL (1) IL227308A (es)
MX (2) MX361355B (es)
SG (1) SG191830A1 (es)
WO (1) WO2012097012A1 (es)

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EA026524B1 (ru) 2017-04-28
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AU2012205681A1 (en) 2013-07-18
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