CO6781506A2 - Uso del agonista de receptor tipo toll para el tratamiento del cáncer - Google Patents

Uso del agonista de receptor tipo toll para el tratamiento del cáncer

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Publication number
CO6781506A2
CO6781506A2 CO13178553A CO13178553A CO6781506A2 CO 6781506 A2 CO6781506 A2 CO 6781506A2 CO 13178553 A CO13178553 A CO 13178553A CO 13178553 A CO13178553 A CO 13178553A CO 6781506 A2 CO6781506 A2 CO 6781506A2
Authority
CO
Colombia
Prior art keywords
toll
receptor agonist
cancer treatment
type
agonist
Prior art date
Application number
CO13178553A
Other languages
English (en)
Inventor
Anatoli Gleiberman
Lyudmila Burdelya
Andrei Gudkov
Original Assignee
Cleveland Biolabs Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cleveland Biolabs Inc filed Critical Cleveland Biolabs Inc
Publication of CO6781506A2 publication Critical patent/CO6781506A2/es

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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
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    • A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
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    • C07—ORGANIC CHEMISTRY
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants

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  • Health & Medical Sciences (AREA)
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  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
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Abstract

La presente invención se refiere a métodos y agentes utilizados para tratar el cáncer en tejidos que expresan el receptor Tipo Toll 5, mediante la proporción de un agonista del receptor Tipo Toll tal como flagelina. La presente invención se refiere también a la protección del hígado de una toxicidad hepática utilizando un agonista del receptor Tipo Toll.
CO13178553A 2011-01-10 2013-07-29 Uso del agonista de receptor tipo toll para el tratamiento del cáncer CO6781506A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161431313P 2011-01-10 2011-01-10

Publications (1)

Publication Number Publication Date
CO6781506A2 true CO6781506A2 (es) 2013-10-31

Family

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Application Number Title Priority Date Filing Date
CO13178553A CO6781506A2 (es) 2011-01-10 2013-07-29 Uso del agonista de receptor tipo toll para el tratamiento del cáncer

Country Status (15)

Country Link
US (7) US9376473B2 (es)
EP (1) EP2663367A4 (es)
JP (1) JP6041444B2 (es)
KR (1) KR20140030132A (es)
CN (1) CN103476458B (es)
AU (1) AU2012205681B2 (es)
BR (1) BR112013017283A2 (es)
CA (1) CA2824438A1 (es)
CL (1) CL2013002001A1 (es)
CO (1) CO6781506A2 (es)
EA (1) EA026524B1 (es)
IL (1) IL227308A (es)
MX (2) MX361355B (es)
SG (1) SG191830A1 (es)
WO (1) WO2012097012A1 (es)

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CA2824438A1 (en) 2012-07-19
US10034926B2 (en) 2018-07-31
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US20140248260A1 (en) 2014-09-04
US10265390B2 (en) 2019-04-23
US20210169972A1 (en) 2021-06-10
US20190275128A1 (en) 2019-09-12
IL227308A0 (en) 2013-09-30
EA026524B1 (ru) 2017-04-28
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US20160206690A1 (en) 2016-07-21
US10780152B2 (en) 2020-09-22
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