HRP20120227T1 - 3-(1,3-benzodioksol-5-il)-6-(4-ciklopropilpiperazin-1-il)piridazin, njegove soli i solvati te njegova uporaba kao antagonista histaminskog h3 receptora - Google Patents
3-(1,3-benzodioksol-5-il)-6-(4-ciklopropilpiperazin-1-il)piridazin, njegove soli i solvati te njegova uporaba kao antagonista histaminskog h3 receptora Download PDFInfo
- Publication number
- HRP20120227T1 HRP20120227T1 HR20120227T HRP20120227T HRP20120227T1 HR P20120227 T1 HRP20120227 T1 HR P20120227T1 HR 20120227 T HR20120227 T HR 20120227T HR P20120227 T HRP20120227 T HR P20120227T HR P20120227 T1 HRP20120227 T1 HR P20120227T1
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- 150000003839 salts Chemical class 0.000 title claims 4
- 239000012453 solvate Substances 0.000 title claims 3
- 229940115480 Histamine H3 receptor antagonist Drugs 0.000 title 1
- 239000003395 histamine H3 receptor antagonist Substances 0.000 title 1
- OMWYTMYLAKPJCE-UHFFFAOYSA-N 3-(1,3-benzodioxol-5-yl)-6-(4-cyclopropylpiperazin-1-yl)pyridazine Chemical compound C1CC1N1CCN(C=2N=NC(=CC=2)C=2C=C3OCOC3=CC=2)CC1 OMWYTMYLAKPJCE-UHFFFAOYSA-N 0.000 claims abstract 2
- 150000001875 compounds Chemical class 0.000 claims 16
- 239000000203 mixture Substances 0.000 claims 11
- 239000008194 pharmaceutical composition Substances 0.000 claims 9
- 239000003814 drug Substances 0.000 claims 4
- 239000013543 active substance Substances 0.000 claims 3
- 208000020401 Depressive disease Diseases 0.000 claims 2
- 208000008589 Obesity Diseases 0.000 claims 2
- 235000019789 appetite Nutrition 0.000 claims 2
- 230000036528 appetite Effects 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 150000004682 monohydrates Chemical group 0.000 claims 2
- 235000020824 obesity Nutrition 0.000 claims 2
- 230000036186 satiety Effects 0.000 claims 2
- 235000019627 satiety Nutrition 0.000 claims 2
- AHOUBRCZNHFOSL-YOEHRIQHSA-N (+)-Casbol Chemical compound C1=CC(F)=CC=C1[C@H]1[C@H](COC=2C=C3OCOC3=CC=2)CNCC1 AHOUBRCZNHFOSL-YOEHRIQHSA-N 0.000 claims 1
- WSEQXVZVJXJVFP-HXUWFJFHSA-N (R)-citalopram Chemical compound C1([C@@]2(C3=CC=C(C=C3CO2)C#N)CCCN(C)C)=CC=C(F)C=C1 WSEQXVZVJXJVFP-HXUWFJFHSA-N 0.000 claims 1
- RTHCYVBBDHJXIQ-MRXNPFEDSA-N (R)-fluoxetine Chemical compound O([C@H](CCNC)C=1C=CC=CC=1)C1=CC=C(C(F)(F)F)C=C1 RTHCYVBBDHJXIQ-MRXNPFEDSA-N 0.000 claims 1
- AHOUBRCZNHFOSL-UHFFFAOYSA-N Paroxetine hydrochloride Natural products C1=CC(F)=CC=C1C1C(COC=2C=C3OCOC3=CC=2)CNCC1 AHOUBRCZNHFOSL-UHFFFAOYSA-N 0.000 claims 1
- 239000000883 anti-obesity agent Substances 0.000 claims 1
- 229940125710 antiobesity agent Drugs 0.000 claims 1
- 235000021407 appetite control Nutrition 0.000 claims 1
- 229960001653 citalopram Drugs 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 229960002464 fluoxetine Drugs 0.000 claims 1
- 230000006698 induction Effects 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 229960002296 paroxetine Drugs 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 229940126570 serotonin reuptake inhibitor Drugs 0.000 claims 1
- 239000003772 serotonin uptake inhibitor Substances 0.000 claims 1
- CMHPUBKZZPSUIQ-UHFFFAOYSA-N 1,3-benzodioxol-5-ylboronic acid Chemical compound OB(O)C1=CC=C2OCOC2=C1 CMHPUBKZZPSUIQ-UHFFFAOYSA-N 0.000 abstract 1
- PORBWTUVFNBTAX-UHFFFAOYSA-N 3-chloro-6-(4-cyclopropylpiperazin-1-yl)pyridazine Chemical compound N1=NC(Cl)=CC=C1N1CCN(C2CC2)CC1 PORBWTUVFNBTAX-UHFFFAOYSA-N 0.000 abstract 1
- 230000002194 synthesizing effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Physical Education & Sports Medicine (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Otolaryngology (AREA)
- Child & Adolescent Psychology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06114615 | 2006-05-29 | ||
| EP06120117 | 2006-09-05 | ||
| PCT/EP2007/054940 WO2007137968A1 (en) | 2006-05-29 | 2007-05-22 | 3- (1, 3-benz0di0x0l-5-yl) -6- (4-cyclopropylpiperazin-1-yl) -pyridazine, its salts and solvates and its use as histamine h3 receptor antagonist |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20120227T1 true HRP20120227T1 (hr) | 2012-04-30 |
Family
ID=38458030
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20120227T HRP20120227T1 (hr) | 2006-05-29 | 2012-03-12 | 3-(1,3-benzodioksol-5-il)-6-(4-ciklopropilpiperazin-1-il)piridazin, njegove soli i solvati te njegova uporaba kao antagonista histaminskog h3 receptora |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US8378097B2 (xx) |
| EP (2) | EP2402324A1 (xx) |
| JP (1) | JP5694661B2 (xx) |
| KR (1) | KR20090040259A (xx) |
| CN (2) | CN102295606A (xx) |
| AT (1) | ATE538116T1 (xx) |
| AU (1) | AU2007267197B2 (xx) |
| BR (1) | BRPI0711370A2 (xx) |
| CA (1) | CA2659570C (xx) |
| CY (1) | CY1112455T1 (xx) |
| DK (1) | DK2079732T3 (xx) |
| EA (1) | EA016026B1 (xx) |
| ES (1) | ES2375872T3 (xx) |
| HR (1) | HRP20120227T1 (xx) |
| IL (1) | IL194681A (xx) |
| MX (1) | MX2008014766A (xx) |
| NZ (1) | NZ571972A (xx) |
| PL (1) | PL2079732T3 (xx) |
| PT (1) | PT2079732E (xx) |
| RS (1) | RS52234B (xx) |
| SG (1) | SG163547A1 (xx) |
| SI (1) | SI2079732T1 (xx) |
| WO (1) | WO2007137968A1 (xx) |
| ZA (1) | ZA200808730B (xx) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2375929T3 (es) | 2005-07-04 | 2012-03-07 | High Point Pharmaceuticals, Llc | Antagonistas del receptor histamina h3. |
| CA2615045A1 (en) * | 2005-07-20 | 2007-01-25 | Merck Frosst Canada Ltd. | Heteroaromatic compounds as inhibitors of stearoyl-coenzyme a delta-9 desaturase |
| CA2632936A1 (en) * | 2005-12-20 | 2007-06-28 | Merck Frosst Canada Ltd. | Heteroaromatic compounds as inhibitors of stearoyl-coenzyme a delta-9 desaturase |
| EP2038256A1 (en) * | 2006-05-23 | 2009-03-25 | TransTech Pharma, Inc | 6- (4-cyclopropylpiperazin-1-yl) -2 ' -methyl- [3, 4 ']-bipyridine and its use as a medicament |
| ATE538116T1 (de) | 2006-05-29 | 2012-01-15 | High Point Pharmaceuticals Llc | 3-(1,3-benyodioxol-5-yl)-6- (4- cyclopropylpiperazin-1-yl)-pyridazin, dessen salze und solvate und dessen verwendung als histamin-h3-rezeptorantagonist |
| US9108948B2 (en) | 2006-06-23 | 2015-08-18 | Abbvie Inc. | Cyclopropyl amine derivatives |
| KR20090024811A (ko) | 2006-06-23 | 2009-03-09 | 아보트 러보러터리즈 | 히스타민 ｈ3 수용체 조절제로서의 사이클로프로필 아민 유도체 |
| EP2014656A3 (en) * | 2007-06-11 | 2011-08-24 | High Point Pharmaceuticals, LLC | New heteocyclic h3 antagonists |
| EP2025674A1 (de) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| US9186353B2 (en) | 2009-04-27 | 2015-11-17 | Abbvie Inc. | Treatment of osteoarthritis pain |
| WO2012037258A1 (en) | 2010-09-16 | 2012-03-22 | Abbott Laboratories | Processes for preparing 1,2-substituted cyclopropyl derivatives |
| WO2013151982A1 (en) | 2012-04-03 | 2013-10-10 | Arena Pharmaceuticals, Inc. | Methods and compounds useful in treating pruritus, and methods for identifying such compounds |
| CN107428729B (zh) | 2015-02-09 | 2021-07-16 | 豪夫迈·罗氏有限公司 | 用于治疗癌症的化合物 |
| US20210355114A1 (en) * | 2018-10-24 | 2021-11-18 | Vanderbilt University | Positive allosteric modulators of the muscarinic acetylcholine receptor m1 |
| WO2022053541A1 (en) * | 2020-09-10 | 2022-03-17 | Eracal Therapeutics Ltd. | Compounds for use as appetite suppressant |
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| US3309370A (en) | 1964-07-16 | 1967-03-14 | Miles Lab | Bicycloalkyl piperazine derivatives and process |
| GB1293565A (en) | 1969-05-03 | 1972-10-18 | Aspro Nicholas Ltd | Aminophthalazines and pharmaceutical compositions thereof |
| US3886161A (en) | 1970-12-14 | 1975-05-27 | Sandoz Ag | 2-Piperazino-3-cyano-5-phenyl-pyridines |
| GB1345880A (en) | 1971-06-18 | 1974-02-06 | Cepbepe | Pyridazine derivatives |
| DE2516040C2 (de) | 1974-06-10 | 1984-12-20 | Dr. Karl Thomae Gmbh, 7950 Biberach | Benzimidazole, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel |
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| EP0204003A4 (en) | 1984-11-27 | 1987-06-03 | Dainippon Pharmaceutical Co | 2- (1-PIPERAZINYL) -4-SUBSTITUTED PHENYLQUINOLINE SCRUBBINGS. |
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| DE3609596A1 (de) | 1986-03-21 | 1987-10-01 | Hoechst Ag | 2-azolylmethyl-2-aryl-1,3-dioxolane und deren salze, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung |
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| DE3803860A1 (de) | 1988-02-09 | 1989-08-17 | Basf Ag | N,n'-disubstituierte piperazine |
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| DK0385237T3 (da) | 1989-03-03 | 1994-07-25 | Dainippon Pharmaceutical Co | 2-(1-Piperazinyl)-4-phenylcycloalkanopyridinderivater, fremgangsmåde til fremstilling deraf og farmaceutisk præparat indeholdende dem |
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| HUP9902056A3 (en) | 1996-01-17 | 2002-02-28 | Novo Nordisk As | Fused 1,2,4-thiadiazine and fused 1,4-thiazine derivatives, their preparation and use |
| EP0923580A1 (en) | 1996-07-26 | 1999-06-23 | Dr. Reddy's Research Foundation | Thiazolidinedione compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions thereof |
| PL192359B1 (pl) | 1996-08-30 | 2006-10-31 | Novo Nordisk As | Pochodna GLP-1(7-37) lub analogu GLP-1(7-37), środek farmaceutyczny oraz zastosowanie pochodnej GLP-1(7-37) lub analogu GLP-1(7-37) |
| DZ2376A1 (fr) | 1996-12-19 | 2002-12-28 | Smithkline Beecham Plc | Dérivés de sulfonamides nouveaux procédé pour leurpréparation et compositions pharmaceutiques les c ontenant. |
| DK0958296T3 (da) | 1996-12-31 | 2003-08-18 | Reddys Lab Ltd Dr | Heterocykliske forbindelser, fremgangsmåde til deres fremstilling og farmaceutiske præparater, der indeholder dem, og deres anvendelse i behandlingen af diabetes og beslægtede sygdomme |
| WO1997041119A1 (en) | 1997-05-02 | 1997-11-06 | Dr. Reddy's Research Foundation | Novel antidiabetic compounds having hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them |
| US6613942B1 (en) | 1997-07-01 | 2003-09-02 | Novo Nordisk A/S | Glucagon antagonists/inverse agonists |
| JP2003514508A (ja) | 1997-07-01 | 2003-04-15 | ノボ ノルディスク アクティーゼルスカブ | グルカゴン拮抗剤／逆作用剤 |
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-
2007
- 2007-05-22 AT AT07729379T patent/ATE538116T1/de active
- 2007-05-22 EP EP11182795A patent/EP2402324A1/en not_active Withdrawn
- 2007-05-22 AU AU2007267197A patent/AU2007267197B2/en not_active Ceased
- 2007-05-22 EA EA200870586A patent/EA016026B1/ru not_active IP Right Cessation
- 2007-05-22 SG SG201004699-3A patent/SG163547A1/en unknown
- 2007-05-22 KR KR1020087028536A patent/KR20090040259A/ko active Search and Examination
- 2007-05-22 NZ NZ571972A patent/NZ571972A/en not_active IP Right Cessation
- 2007-05-22 RS RS20120078A patent/RS52234B/en unknown
- 2007-05-22 WO PCT/EP2007/054940 patent/WO2007137968A1/en active Application Filing
- 2007-05-22 PL PL07729379T patent/PL2079732T3/pl unknown
- 2007-05-22 JP JP2009512547A patent/JP5694661B2/ja not_active Expired - Fee Related
- 2007-05-22 CN CN2011101822989A patent/CN102295606A/zh active Pending
- 2007-05-22 DK DK07729379.3T patent/DK2079732T3/da active
- 2007-05-22 MX MX2008014766A patent/MX2008014766A/es active IP Right Grant
- 2007-05-22 EP EP07729379A patent/EP2079732B9/en active Active
- 2007-05-22 US US12/302,132 patent/US8378097B2/en not_active Expired - Fee Related
- 2007-05-22 ES ES07729379T patent/ES2375872T3/es active Active
- 2007-05-22 CN CNA2007800197395A patent/CN101460487A/zh active Pending
- 2007-05-22 PT PT07729379T patent/PT2079732E/pt unknown
- 2007-05-22 CA CA2659570A patent/CA2659570C/en not_active Expired - Fee Related
- 2007-05-22 SI SI200730845T patent/SI2079732T1/sl unknown
- 2007-05-22 BR BRPI0711370-6A patent/BRPI0711370A2/pt not_active IP Right Cessation
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2008
- 2008-10-12 IL IL194681A patent/IL194681A/en not_active IP Right Cessation
- 2008-10-13 ZA ZA2008/08730A patent/ZA200808730B/en unknown
-
2012
- 2012-03-07 CY CY20121100230T patent/CY1112455T1/el unknown
- 2012-03-12 HR HR20120227T patent/HRP20120227T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2007267197B2 (en) | 2011-12-01 |
| MX2008014766A (es) | 2009-03-06 |
| KR20090040259A (ko) | 2009-04-23 |
| ES2375872T9 (es) | 2012-07-19 |
| BRPI0711370A2 (pt) | 2011-11-01 |
| EP2402324A1 (en) | 2012-01-04 |
| EP2079732B1 (en) | 2011-12-21 |
| SG163547A1 (en) | 2010-08-30 |
| SI2079732T1 (sl) | 2012-03-30 |
| US8378097B2 (en) | 2013-02-19 |
| ATE538116T1 (de) | 2012-01-15 |
| WO2007137968A1 (en) | 2007-12-06 |
| DK2079732T3 (da) | 2012-01-23 |
| CN102295606A (zh) | 2011-12-28 |
| AU2007267197A1 (en) | 2007-12-06 |
| EP2079732A1 (en) | 2009-07-22 |
| CN101460487A (zh) | 2009-06-17 |
| JP2009538861A (ja) | 2009-11-12 |
| PL2079732T3 (pl) | 2012-05-31 |
| NZ571972A (en) | 2011-09-30 |
| RS52234B (en) | 2012-10-31 |
| JP5694661B2 (ja) | 2015-04-01 |
| PT2079732E (pt) | 2012-02-02 |
| EP2079732B9 (en) | 2012-03-21 |
| EA200870586A1 (ru) | 2009-10-30 |
| CA2659570A1 (en) | 2007-12-06 |
| ES2375872T3 (es) | 2012-03-07 |
| ZA200808730B (en) | 2010-02-24 |
| CA2659570C (en) | 2015-10-06 |
| CY1112455T1 (el) | 2015-12-09 |
| EA016026B1 (ru) | 2012-01-30 |
| IL194681A (en) | 2013-09-30 |
| US20090176793A1 (en) | 2009-07-09 |
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