PL2079732T3 - 3-(1,3-benzodioksol-5-ylo)-6-(4-cyklopropylopiperazyn-1-ylo)-pirydazyna, jej sole i solwaty oraz jej zastosowanie jako antagonisty receptora histaminowego h3 - Google Patents
3-(1,3-benzodioksol-5-ylo)-6-(4-cyklopropylopiperazyn-1-ylo)-pirydazyna, jej sole i solwaty oraz jej zastosowanie jako antagonisty receptora histaminowego h3Info
- Publication number
- PL2079732T3 PL2079732T3 PL07729379T PL07729379T PL2079732T3 PL 2079732 T3 PL2079732 T3 PL 2079732T3 PL 07729379 T PL07729379 T PL 07729379T PL 07729379 T PL07729379 T PL 07729379T PL 2079732 T3 PL2079732 T3 PL 2079732T3
- Authority
- PL
- Poland
- Prior art keywords
- pyridazine
- cyclopropylpiperazin
- histamine
- solvates
- salts
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Immunology (AREA)
- Hospice & Palliative Care (AREA)
- Emergency Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Anesthesiology (AREA)
- Child & Adolescent Psychology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Otolaryngology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06114615 | 2006-05-29 | ||
EP06120117 | 2006-09-05 | ||
EP07729379A EP2079732B9 (en) | 2006-05-29 | 2007-05-22 | 3- (1, 3-benz0di0x0l-5-yl) -6- (4-cyclopropylpiperazin-1-yl) -pyridazine, its salts and solvates and its use as histamine h3 receptor antagonist |
PCT/EP2007/054940 WO2007137968A1 (en) | 2006-05-29 | 2007-05-22 | 3- (1, 3-benz0di0x0l-5-yl) -6- (4-cyclopropylpiperazin-1-yl) -pyridazine, its salts and solvates and its use as histamine h3 receptor antagonist |
Publications (1)
Publication Number | Publication Date |
---|---|
PL2079732T3 true PL2079732T3 (pl) | 2012-05-31 |
Family
ID=38458030
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL07729379T PL2079732T3 (pl) | 2006-05-29 | 2007-05-22 | 3-(1,3-benzodioksol-5-ylo)-6-(4-cyklopropylopiperazyn-1-ylo)-pirydazyna, jej sole i solwaty oraz jej zastosowanie jako antagonisty receptora histaminowego h3 |
Country Status (24)
Country | Link |
---|---|
US (1) | US8378097B2 (pl) |
EP (2) | EP2079732B9 (pl) |
JP (1) | JP5694661B2 (pl) |
KR (1) | KR20090040259A (pl) |
CN (2) | CN101460487A (pl) |
AT (1) | ATE538116T1 (pl) |
AU (1) | AU2007267197B2 (pl) |
BR (1) | BRPI0711370A2 (pl) |
CA (1) | CA2659570C (pl) |
CY (1) | CY1112455T1 (pl) |
DK (1) | DK2079732T3 (pl) |
EA (1) | EA016026B1 (pl) |
ES (1) | ES2375872T3 (pl) |
HR (1) | HRP20120227T1 (pl) |
IL (1) | IL194681A (pl) |
MX (1) | MX2008014766A (pl) |
NZ (1) | NZ571972A (pl) |
PL (1) | PL2079732T3 (pl) |
PT (1) | PT2079732E (pl) |
RS (1) | RS52234B (pl) |
SG (1) | SG163547A1 (pl) |
SI (1) | SI2079732T1 (pl) |
WO (1) | WO2007137968A1 (pl) |
ZA (1) | ZA200808730B (pl) |
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WO2007009236A1 (en) * | 2005-07-20 | 2007-01-25 | Merck Frosst Canada Ltd. | Heteroaromatic compounds as inhibitors of stearoyl-coenzyme a delta-9 desaturase |
EP1966183A4 (en) * | 2005-12-20 | 2010-12-29 | Merck Frosst Canada Ltd | HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A-DELTA-9-DESATURASE |
JP2009537596A (ja) * | 2006-05-23 | 2009-10-29 | ハイ ポイント ファーマシューティカルズ,リミティド ライアビリティ カンパニー | 6−(4−シクロプロピルピペリジン−1−イル)−2’−メチル−[3,4’]−ビピリジン及びその医薬としての使用 |
WO2007137968A1 (en) | 2006-05-29 | 2007-12-06 | High Point Pharmaceuticals, Llc | 3- (1, 3-benz0di0x0l-5-yl) -6- (4-cyclopropylpiperazin-1-yl) -pyridazine, its salts and solvates and its use as histamine h3 receptor antagonist |
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EP2014656A3 (en) * | 2007-06-11 | 2011-08-24 | High Point Pharmaceuticals, LLC | New heteocyclic h3 antagonists |
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-
2007
- 2007-05-22 WO PCT/EP2007/054940 patent/WO2007137968A1/en active Application Filing
- 2007-05-22 CN CNA2007800197395A patent/CN101460487A/zh active Pending
- 2007-05-22 CN CN2011101822989A patent/CN102295606A/zh active Pending
- 2007-05-22 AU AU2007267197A patent/AU2007267197B2/en not_active Ceased
- 2007-05-22 BR BRPI0711370-6A patent/BRPI0711370A2/pt not_active IP Right Cessation
- 2007-05-22 SI SI200730845T patent/SI2079732T1/sl unknown
- 2007-05-22 CA CA2659570A patent/CA2659570C/en not_active Expired - Fee Related
- 2007-05-22 PT PT07729379T patent/PT2079732E/pt unknown
- 2007-05-22 RS RS20120078A patent/RS52234B/en unknown
- 2007-05-22 MX MX2008014766A patent/MX2008014766A/es active IP Right Grant
- 2007-05-22 JP JP2009512547A patent/JP5694661B2/ja not_active Expired - Fee Related
- 2007-05-22 DK DK07729379.3T patent/DK2079732T3/da active
- 2007-05-22 EA EA200870586A patent/EA016026B1/ru not_active IP Right Cessation
- 2007-05-22 EP EP07729379A patent/EP2079732B9/en active Active
- 2007-05-22 EP EP11182795A patent/EP2402324A1/en not_active Withdrawn
- 2007-05-22 AT AT07729379T patent/ATE538116T1/de active
- 2007-05-22 ES ES07729379T patent/ES2375872T3/es active Active
- 2007-05-22 PL PL07729379T patent/PL2079732T3/pl unknown
- 2007-05-22 KR KR1020087028536A patent/KR20090040259A/ko active Search and Examination
- 2007-05-22 SG SG201004699-3A patent/SG163547A1/en unknown
- 2007-05-22 US US12/302,132 patent/US8378097B2/en not_active Expired - Fee Related
- 2007-05-22 NZ NZ571972A patent/NZ571972A/en not_active IP Right Cessation
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- 2012-03-12 HR HR20120227T patent/HRP20120227T1/hr unknown
Also Published As
Publication number | Publication date |
---|---|
AU2007267197B2 (en) | 2011-12-01 |
SI2079732T1 (sl) | 2012-03-30 |
NZ571972A (en) | 2011-09-30 |
ZA200808730B (en) | 2010-02-24 |
ES2375872T3 (es) | 2012-03-07 |
JP5694661B2 (ja) | 2015-04-01 |
CN102295606A (zh) | 2011-12-28 |
CY1112455T1 (el) | 2015-12-09 |
WO2007137968A1 (en) | 2007-12-06 |
HRP20120227T1 (hr) | 2012-04-30 |
SG163547A1 (en) | 2010-08-30 |
AU2007267197A1 (en) | 2007-12-06 |
CA2659570C (en) | 2015-10-06 |
EP2079732B9 (en) | 2012-03-21 |
PT2079732E (pt) | 2012-02-02 |
DK2079732T3 (da) | 2012-01-23 |
CN101460487A (zh) | 2009-06-17 |
CA2659570A1 (en) | 2007-12-06 |
ES2375872T9 (es) | 2012-07-19 |
BRPI0711370A2 (pt) | 2011-11-01 |
RS52234B (en) | 2012-10-31 |
US8378097B2 (en) | 2013-02-19 |
MX2008014766A (es) | 2009-03-06 |
EP2079732B1 (en) | 2011-12-21 |
EA016026B1 (ru) | 2012-01-30 |
IL194681A (en) | 2013-09-30 |
EP2402324A1 (en) | 2012-01-04 |
KR20090040259A (ko) | 2009-04-23 |
US20090176793A1 (en) | 2009-07-09 |
JP2009538861A (ja) | 2009-11-12 |
EP2079732A1 (en) | 2009-07-22 |
EA200870586A1 (ru) | 2009-10-30 |
ATE538116T1 (de) | 2012-01-15 |
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