HRP20100384T1 - Antibakterijski derivati kvinolina - Google Patents

Antibakterijski derivati kvinolina Download PDF

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Publication number
HRP20100384T1
HRP20100384T1 HR20100384T HRP20100384T HRP20100384T1 HR P20100384 T1 HRP20100384 T1 HR P20100384T1 HR 20100384 T HR20100384 T HR 20100384T HR P20100384 T HRP20100384 T HR P20100384T HR P20100384 T1 HRP20100384 T1 HR P20100384T1
Authority
HR
Croatia
Prior art keywords
alkyl
aryl
mono
het
compound according
Prior art date
Application number
HR20100384T
Other languages
English (en)
Croatian (hr)
Inventor
Emile Georges Guillemont J�r�me
Madeleine Simone Motte Magali
Jozef Lodewijk Marcel Andries Koenraad
Koul Anil
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of HRP20100384T1 publication Critical patent/HRP20100384T1/hr

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • C07D215/227Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465Nicotine; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
HR20100384T 2006-12-06 2007-12-04 Antibakterijski derivati kvinolina HRP20100384T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06125521 2006-12-06
PCT/EP2007/063315 WO2008068269A1 (en) 2006-12-06 2007-12-04 Antibacterial quinoline derivatives

Publications (1)

Publication Number Publication Date
HRP20100384T1 true HRP20100384T1 (hr) 2010-08-31

Family

ID=37944337

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20100384T HRP20100384T1 (hr) 2006-12-06 2007-12-04 Antibakterijski derivati kvinolina

Country Status (29)

Country Link
US (1) US7998979B2 (enExample)
EP (1) EP2086941B1 (enExample)
JP (1) JP5356245B2 (enExample)
KR (1) KR101490221B1 (enExample)
CN (1) CN101541752B (enExample)
AR (1) AR064150A1 (enExample)
AT (1) ATE465994T1 (enExample)
AU (1) AU2007328889B2 (enExample)
BR (1) BRPI0720251B8 (enExample)
CA (1) CA2668520C (enExample)
CL (1) CL2007003516A1 (enExample)
CY (1) CY1110706T1 (enExample)
DE (1) DE602007006231D1 (enExample)
DK (1) DK2086941T3 (enExample)
ES (1) ES2344535T3 (enExample)
HR (1) HRP20100384T1 (enExample)
IL (1) IL199081A (enExample)
JO (1) JO2685B1 (enExample)
ME (1) ME01073B (enExample)
MX (1) MX2009005980A (enExample)
NO (1) NO341995B1 (enExample)
NZ (1) NZ576673A (enExample)
PL (1) PL2086941T3 (enExample)
PT (1) PT2086941E (enExample)
RS (1) RS51390B (enExample)
RU (1) RU2446159C2 (enExample)
SI (1) SI2086941T1 (enExample)
TW (1) TWI412364B (enExample)
WO (1) WO2008068269A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104254527B (zh) 2012-04-27 2017-05-31 詹森药业有限公司 抗菌的喹啉衍生物
AU2013254670B2 (en) 2012-04-27 2017-03-30 Janssen Pharmaceutica Nv Antibacterial quinoline derivatives
CN104650054B (zh) * 2013-11-25 2019-09-13 重庆医药工业研究院有限责任公司 一种抗结核菌的喹啉噻吩芳氧乙胺衍生物
WO2018048882A1 (en) 2016-09-06 2018-03-15 The Research Foundation For The State University Of New York Positron imaging tomography imaging agent composition and method for bacterial infection
JP2025510646A (ja) 2022-03-14 2025-04-15 スラップ ファーマシューティカルズ エルエルシー 多環式化合物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6033389B2 (ja) * 1979-02-22 1985-08-02 日産化学工業株式会社 複素環エ−テル系フェノシキ脂肪酸誘導体、その製造法および該誘導体を含有する除草剤
WO1998018326A1 (en) 1996-10-28 1998-05-07 Department Of The Army, U.S. Government Compounds, compositions and methods for treating antibiotic-resistant infections
KR20040055774A (ko) * 2001-07-31 2004-06-26 웨인 스테이트 유니버시티 퀴놀린 유도체 및 항종양제로서 그의 용도
DK2301544T3 (da) * 2002-07-25 2013-01-02 Janssen Pharmaceutica Nv Quinolinderivater som mellemprodukter til mykobakterielle inhibitorer
WO2005070430A1 (en) * 2004-01-23 2005-08-04 Janssen Pharmaceutica N.V. Quinoline derivatives and use thereof as mycobacterial inhibitors
WO2005070924A1 (en) 2004-01-23 2005-08-04 Janssen Pharmaceutica N.V. Substituted quinolines and their use as mycobacterial inhibitors
ES2306098T3 (es) * 2004-01-29 2008-11-01 Janssen Pharmaceutica Nv Derivados de quinolina para uso como inhibidores de micobacterias.
EP1753427B1 (en) * 2004-05-28 2008-04-02 Janssen Pharmaceutica N.V. Use of substituted quinoline derivatives for the treatment of drug resistant mycobacterial diseases
ME02935B (me) 2004-09-28 2018-04-20 Janssen Pharmaceutica Nv Vezujući domen bakterijske atp sintaze

Also Published As

Publication number Publication date
HK1137428A1 (en) 2010-07-30
NO20092540L (no) 2009-09-07
DK2086941T3 (da) 2010-08-09
JP5356245B2 (ja) 2013-12-04
CN101541752A (zh) 2009-09-23
TW200845987A (en) 2008-12-01
AU2007328889B2 (en) 2012-12-06
BRPI0720251B1 (pt) 2020-10-06
ATE465994T1 (de) 2010-05-15
CA2668520A1 (en) 2008-06-12
PL2086941T3 (pl) 2010-10-29
SI2086941T1 (sl) 2010-08-31
NZ576673A (en) 2011-09-30
AU2007328889A1 (en) 2008-06-12
DE602007006231D1 (de) 2010-06-10
ES2344535T3 (es) 2010-08-30
BRPI0720251A2 (pt) 2014-01-07
WO2008068269A1 (en) 2008-06-12
US7998979B2 (en) 2011-08-16
PT2086941E (pt) 2010-07-14
RU2009125525A (ru) 2011-01-20
CL2007003516A1 (es) 2008-07-11
EP2086941A1 (en) 2009-08-12
CN101541752B (zh) 2013-07-17
JP2010511670A (ja) 2010-04-15
US20100063061A1 (en) 2010-03-11
CY1110706T1 (el) 2015-06-10
TWI412364B (zh) 2013-10-21
NO341995B1 (no) 2018-03-12
EP2086941B1 (en) 2010-04-28
MX2009005980A (es) 2009-06-16
ME01073B (me) 2012-10-20
KR101490221B1 (ko) 2015-02-05
CA2668520C (en) 2016-01-26
AR064150A1 (es) 2009-03-18
RU2446159C2 (ru) 2012-03-27
RS51390B (sr) 2011-02-28
JO2685B1 (en) 2013-03-03
KR20090087071A (ko) 2009-08-14
IL199081A (en) 2013-08-29
BRPI0720251B8 (pt) 2021-05-25

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