ATE465994T1 - Antibakterielle chinolinderivate - Google Patents

Antibakterielle chinolinderivate

Info

Publication number
ATE465994T1
ATE465994T1 AT07847813T AT07847813T ATE465994T1 AT E465994 T1 ATE465994 T1 AT E465994T1 AT 07847813 T AT07847813 T AT 07847813T AT 07847813 T AT07847813 T AT 07847813T AT E465994 T1 ATE465994 T1 AT E465994T1
Authority
AT
Austria
Prior art keywords
quinoline derivatives
antibacterial quinoline
antibacterial
derivatives
quinoline
Prior art date
Application number
AT07847813T
Other languages
English (en)
Inventor
Jerome Emile Georges Guillemont
Magali Madeleine Simone Motte
Koenraad Jozef Lodewijk Marce Andries
Anil Koul
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of ATE465994T1 publication Critical patent/ATE465994T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
AT07847813T 2006-12-06 2007-12-04 Antibakterielle chinolinderivate ATE465994T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06125521 2006-12-06
PCT/EP2007/063315 WO2008068269A1 (en) 2006-12-06 2007-12-04 Antibacterial quinoline derivatives

Publications (1)

Publication Number Publication Date
ATE465994T1 true ATE465994T1 (de) 2010-05-15

Family

ID=37944337

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07847813T ATE465994T1 (de) 2006-12-06 2007-12-04 Antibakterielle chinolinderivate

Country Status (30)

Country Link
US (1) US7998979B2 (de)
EP (1) EP2086941B1 (de)
JP (1) JP5356245B2 (de)
KR (1) KR101490221B1 (de)
CN (1) CN101541752B (de)
AR (1) AR064150A1 (de)
AT (1) ATE465994T1 (de)
AU (1) AU2007328889B2 (de)
BR (1) BRPI0720251B8 (de)
CA (1) CA2668520C (de)
CL (1) CL2007003516A1 (de)
CY (1) CY1110706T1 (de)
DE (1) DE602007006231D1 (de)
DK (1) DK2086941T3 (de)
ES (1) ES2344535T3 (de)
HK (1) HK1137428A1 (de)
HR (1) HRP20100384T1 (de)
IL (1) IL199081A (de)
JO (1) JO2685B1 (de)
ME (1) ME01073B (de)
MX (1) MX2009005980A (de)
NO (1) NO341995B1 (de)
NZ (1) NZ576673A (de)
PL (1) PL2086941T3 (de)
PT (1) PT2086941E (de)
RS (1) RS51390B (de)
RU (1) RU2446159C2 (de)
SI (1) SI2086941T1 (de)
TW (1) TWI412364B (de)
WO (1) WO2008068269A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9617244B2 (en) 2012-04-27 2017-04-11 Janssen Pharmaceutica Nv Antibacterial quinoline derivatives
AU2013254674B2 (en) 2012-04-27 2017-02-02 Janssen Pharmaceutica Nv Antibacterial quinoline derivatives
CN104650054B (zh) * 2013-11-25 2019-09-13 重庆医药工业研究院有限责任公司 一种抗结核菌的喹啉噻吩芳氧乙胺衍生物
US11857352B2 (en) 2016-09-06 2024-01-02 The Research Foundation For The State University Of New York Positron imaging tomography imaging agent composition and method for bacterial infection

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6033389B2 (ja) * 1979-02-22 1985-08-02 日産化学工業株式会社 複素環エ−テル系フェノシキ脂肪酸誘導体、その製造法および該誘導体を含有する除草剤
JP2001503411A (ja) 1996-10-28 2001-03-13 ディパートメント オブ ジ アーミー，ユー．エス．ガバメント 抗生物質耐性感染症の処置のための化合物、組成物および方法
ATE287397T1 (de) * 2001-07-31 2005-02-15 Univ Wayne State Chinoline derivate und ihre anwendung als antitumor agentien
EP1527050B1 (de) * 2002-07-25 2010-04-07 Janssen Pharmaceutica N.V. Chinolinderivate und deren verwendung als mycobakterielle inhibitoren
ES2306082T3 (es) 2004-01-23 2008-11-01 Janssen Pharmaceutica Nv Quinolinas sustituidas y su utilizacion como inhibidores micobacterianos.
CN1909907B (zh) * 2004-01-23 2010-06-23 詹森药业有限公司 喹啉衍生物及其在制备分枝杆菌抑制剂中的用途
KR101160183B1 (ko) 2004-01-29 2012-06-26 얀센 파마슈티카 엔.브이. 마이코박테리아 저해제로서 사용하기 위한 퀴놀린 유도체
KR20130024969A (ko) * 2004-05-28 2013-03-08 얀센 파마슈티카 엔.브이. 약물 내성 마이코박테리아 질환 치료를 위한 치환된 퀴놀린 유도체의 용도
DK1797115T3 (en) 2004-09-28 2017-10-02 Janssen Pharmaceutica Nv BACTERIAL ATP SYNTHASE BINDING DOMAIN.

Also Published As

Publication number Publication date
KR20090087071A (ko) 2009-08-14
WO2008068269A1 (en) 2008-06-12
RU2009125525A (ru) 2011-01-20
NO341995B1 (no) 2018-03-12
CN101541752A (zh) 2009-09-23
CA2668520C (en) 2016-01-26
JP2010511670A (ja) 2010-04-15
TW200845987A (en) 2008-12-01
PT2086941E (pt) 2010-07-14
DE602007006231D1 (de) 2010-06-10
EP2086941B1 (de) 2010-04-28
AU2007328889B2 (en) 2012-12-06
HK1137428A1 (en) 2010-07-30
BRPI0720251B8 (pt) 2021-05-25
RU2446159C2 (ru) 2012-03-27
US20100063061A1 (en) 2010-03-11
KR101490221B1 (ko) 2015-02-05
CY1110706T1 (el) 2015-06-10
JP5356245B2 (ja) 2013-12-04
EP2086941A1 (de) 2009-08-12
DK2086941T3 (da) 2010-08-09
TWI412364B (zh) 2013-10-21
BRPI0720251B1 (pt) 2020-10-06
CN101541752B (zh) 2013-07-17
HRP20100384T1 (hr) 2010-08-31
SI2086941T1 (sl) 2010-08-31
JO2685B1 (en) 2013-03-03
MX2009005980A (es) 2009-06-16
BRPI0720251A2 (pt) 2014-01-07
RS51390B (en) 2011-02-28
AU2007328889A1 (en) 2008-06-12
AR064150A1 (es) 2009-03-18
PL2086941T3 (pl) 2010-10-29
CA2668520A1 (en) 2008-06-12
ES2344535T3 (es) 2010-08-30
ME01073B (me) 2012-10-20
NO20092540L (no) 2009-09-07
CL2007003516A1 (es) 2008-07-11
US7998979B2 (en) 2011-08-16
NZ576673A (en) 2011-09-30
IL199081A (en) 2013-08-29

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